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      • KCI등재

        Hot Deformation Behavior and Recrystallization Mechanism in an As-Cast CoNi-Based Superalloy

        Yong Guan,Yongchang Liu,Zongqing Ma,Huijun Li,Hongyao Yu 대한금속·재료학회 2022 METALS AND MATERIALS International Vol.28 No.6

        The hot deformation behavior of as-cast CoNi-based superalloy was investigated by means of hot compression tests. Thecorresponding microstructure evolution after hot deformation was examined by optical microscope, as well as the TEMtechnique. The constitutive equation and processing map as a function of deformation temperature and strain rate were developed. Results show that the efficiency peak of the processing map is 0.38 at the temperature of 1130 °C and the strain rate of0.01 s−1. The discontinuous dynamic recrystallization (DDRX) related to the strain-induced grain boundary migration (SIBM)is the dominant recrystallization mechanism during hot working. Meanwhile, the DRX also occurs by forming sub-grainsaround MC carbides and shear band. In addition, the existence of fine γ′ precipitates are found to retard the recrystallization.

      • KCI등재

        RO 및 NF막에서의 부식질에 의한 Fouling 및 미량오염물질의 제거

        왕창근,차준철,이용현,김수동,류주환 대한상하수도학회 2004 상하수도학회지 Vol.18 No.1

        This study investigated the phenomena of membrane fouling by NOM and the effect of the fouling on removal of micro-pollutants. NOM has a great effect on decline of permeate flux. Permeate flow rate was reduced by 88% in RO and 34.8% in NF for 323hr operation period. Removal rate of UV_(254), is 87.4% in RO and 78.5% in NF and removal rate of DOC is 42.7% in RO and 32.9% in NF for 2㎎/l humic acid. Removal efficiency of the micmpollutants by the RO and NF membranes fouled by humic acid was mostly lower than that by the new membrane. The concentration polarization which affects the flux and the rejection was thought to occur in the active layer of the membrane, as the membrane was getting fouled.

      • SCOPUS

        Relationships between Inbound Tourism, Financial Development, and Economic Growth: An Empirical Study of Fujian Province, China

        An Lin LIU(An Lin LIU),Yong Cen LIU(Yong Cen LIU) 한국유통과학회 2023 The Journal of Asian Finance, Economics and Busine Vol.10 No.2

        This paper mainly studies the relationship between financial development, inbound tourism development, and economic growth rate in Fujian Province, China. This study uses the data of real GDP, foreign exchange income from international tourism, and financial interrelations ratio from 1994 to 2019. In the analysis process, the Johansen cointegration test is first used to analyze whether the three have a long-term equilibrium relationship. Then the vector error correction model is established to test the restrictive relationship among the three. Next, the Granger causality test assesses whether the three have a causal relationship. Finally, the contribution rate of the three is analyzed by variance decomposition. The above methods show the following conclusions: first, the three have a long-term equilibrium relationship. Secondly, in the short term, local economic growth is constrained by inbound tourism and financial development. Thirdly, there is a causal relationship between economic growth and inbound tourism in Fujian, while there is a unidirectional causal relationship between financial development and economic growth, financial development, and inbound tourism. Fourthly, the contribution rate of inbound tourism to economic growth fluctuations in Fujian is higher than that of financial development.

      • KCI등재

        Optimization of preparation and properties of Gardenia yellow pigment-loaded alginate beads

        Yong Liu,Qing Zhou,Yan-Mei He,Xiu-Yun Ma,Lin-Na Liu,Yong-Jian Ke 한국화학공학회 2021 Korean Journal of Chemical Engineering Vol.38 No.8

        Gardenia yellow pigment (GYP) loaded alginate beads were prepared by the ionic gelation technique, and the preparation parameters were optimized by response surface methodology for high encapsulation efficiency. The optimized parameters were alginate concentration of 3.3%, CaCl2 concentration of 2.4%, and GYP concentration of 3.2mg/mL, under which the encapsulation efficiency was 73.61%. The surface morphology and bead size analysis showed that the GYP-loaded alginate beads had a roughly spherical morphology with a wrinkled surface, and their average diameter was 0.87 mm. In vitro release test revealed that the GYP release had a pH-dependent release profile and a two-step release process. The Rigter-Peppas model was the most proper model to assess the GYP release from alginate beads. The release mechanism of GYP at pH 1.2 and 7.4 was non-Fickian transport and case-II transport, respectively. The 2,2-diphenyl-1-picrylhydrazyl assay indicated that the encapsulated GYP had effectively maintained 82.56% of the antioxidant activity.

      • KCI등재

        Developing Brønsted–Lewis acids bifunctionalized ionic liquids based heteropolyacid hybrid as high-efficient solid acids in esterification and biomass conversion

        Yong Liu,Yuefeng Wu,Miaojun Su,Weihua Liu,Xiying Li,Fujian Liu 한국공업화학회 2020 Journal of Industrial and Engineering Chemistry Vol.92 No.-

        A class of Brønsted–Lewis acid bifunctionalized ionic liquids based heteropolyacid hybrid (BLA-ILs-HPA)solid acids were developed by combining the double sulfonic groups grafted, ionic liquids basedheteropolyacid hybrid with Lewis acidic centers (M = Zn, Co, Fe, Ni, Cu). The prepared BLA-ILs-HPA showboth Brønsted and Lewis acidic sites with extremely-high acid strength and enhanced stabilities, asdetermined by FT-IR, Py-IR, TG, XPS and 31P solid state NMR results. BLA-ILs-HPA were successfullyapplied in esterification camphene with acetic acid to produce isobornyl acetate, and dehydration ofglucose to produce 5-hydrozymethylfural. BLA-ILs-HPA show enhanced catalytic activities in comparisonwith various acid catalysts. The effects of reaction temperatures, initial reactant molar ratio, catalystdosage, and reaction time were studied in detail. The optimal reaction conditions were obtained, and theexperimental data was successfully correlated by a pseudohomogeneous (PH) reaction kinetic model inthe temperature range of 313.15–333.15 K. The calculated values obtained by the reaction kinetic modelwere in good agreement with the experimental data. Moreover, as a heterogeneous reaction catalyst,BLA-ILs-HPA can be recovered by simple treatment. After six times cycling, the decreasing in the catalyticactivity of BLA-ILs-HPA could not be observed significantly, suggesting their good reusability.

      • KCI등재

        In Vitro Evaluation and Monitoring of the Expression Level and Localization of Aldose Reductase Using Functionalized Quantum Dots and EGFP

        Xiaomin Liu,Chengbin Yang,Jing Liu,Jianwei Liu,Rui Hu,Hongwei Lian,Guimiao Lin,Liwei Liu,Ken-Tye Yong,Ling Ye 한국생물공학회 2015 Biotechnology and Bioprocess Engineering Vol.20 No.4

        The optimization of aldose reductase (AR) expression levels and tracking of the AR expression sites within the cell is an essential step in developing a platform for the effective production of aldose reductase inhibitors (ARIs). In this study, we have demonstrated the use of both immunocytochemistry and quantum dots-based immunofluorescence techniques for observing and detecting the expression level and localization of AR in the cytoplasm and cell membrane of a eukaryotic cell model with high levels of AR protein expression. Our results show that high expression levels of human AR can be achieved using the eukaryotic cell model that we have developed. The overexpressed AR can be used for translational studies of hAR and the screening of ARIs. More importantly, the use of the established quantum dots-based immunofluorescence technique in the intracellular labeling of AR allows the determination of the expression and distribution of the AR gene. Overall, the use of the interdisciplinary approach of both genetic engineering and quantum dot-based immunofluorescence allows not only the effective production of a desired protein, but also the determination of the cellular localization of such an expressed protein.

      • KCI등재

        SALT-INDUCED CHLOROPLAST PROTEIN (SCP) is Involved in Plant Tolerance to Salt Stress in Arabidopsis

        Yong Zhuang,Yangxuan Liu,Yuxiang Li,Ming Wei,Yuying Tang,Penghui Li,Zhijian Liu,Hui Li,Weizao Huang,Songhu Wang 한국식물학회 2019 Journal of Plant Biology Vol.62 No.6

        Soil salinization threats the agricultural productionand food security worldwide. Salt stress induced plantsenescence and chloroplast degradation. However, it remainslargely unknown how the chloroplast-localized proteins affectplant response to salt stress. Here, we characterized a novelgene (At5g39520) in Arabidopsis, which is induced by saltstress and encodes a chloroplast-localized protein. Thus, thisgene was named SALT-INDUCED CHLOROPLAST PROTEIN(SCP). A T-DNA insertion mutant of SCP gene (scp-1)showed the enhanced tolerance to salt stress, as indicated bythe increased survival rates, fresh weights and chlorophyllcontents compared with wild type plants under salt treatment. Salt-induced leaf senescence was also delayed in scp-1 mutant. The scp-1 complementation line and SCP overexpressionlines displayed the hypersensitivity to salt stress. The qRTPCRanalysis indicated that the transcripts of CHLOROPLASTVESICULATION (CV), which mediates stress-inducedchloroplast degradation, were altered in scp-1 mutant andSCP overexpression lines. Taken together, our results suggestthat SCP gene plays a negative role in response to salt stress andhas potential application for genetic modification of improvingplant tolerance to salt stress.

      • SCIESCOPUSKCI등재

        Centromere protein U enhances the progression of bladder cancer by promoting mitochondrial ribosomal protein s28 expression

        Liu, Bei-Bei,Ma, Tao,Sun, Wei,Gao, Wu-Yue,Liu, Jian-Min,Li, Li-Qiang,Li, Wen-Yong,Wang, Sheng,Guo, Yuan-Yuan The Korean Society of Pharmacology 2021 The Korean Journal of Physiology & Pharmacology Vol.25 No.2

        Bladder cancer is one of the most common types of cancer. Most gene mutations related to bladder cancer are dominantly acquired gene mutations and are not inherited. Previous comparative transcriptome analysis of urinary bladder cancer and control samples has revealed a set of genes that may play a role in tumor progression. Here we set out to investigate further the expression of two candidate genes, centromere protein U (CENPU) and mitochondrial ribosomal protein s28 (MRPS28) to better understand their role in bladder cancer pathogenesis. Our results confirmed that CENPU is up-regulated in human bladder cancer tissues at mRNA and protein levels. Gain-of-function and loss-of-function studies in T24 human urinary bladder cancer cell line revealed a hierarchical relationship between CENPU and MRPS28 in the regulation of cell viability, migration and invasion activity. CENPU expression was also up-regulated in in vivo nude mice xenograft model of bladder cancer and mice overexpressing CENPU had significantly higher tumor volume. In summary, our findings identify CENPU and MRPS28 in the molecular pathogenesis of bladder cancer and suggest that CENPU enhances the progression of bladder cancer by promoting MRPS28 expression.

      • KCI등재

        Feasibility Study on Long-Term Continuous Ethanol Production from Cassava Supernatant by Immobilized Yeast Cells in Packed Bed Reactor

        Liu Qingguo,Zhao Nan,Zou Yanan,Ying Hanjie,Dong Liu,Chen Yong 한국미생물·생명공학회 2020 Journal of microbiology and biotechnology Vol.30 No.8

        In this study, yeast cell immobilization was carried out in a packed bed reactor (PBR) to investigate the effects of the volumetric capacity of carriers as well as the different fermentation modes on fuel ethanol production. An optimal volumetric capacity of 10 g/l was found to obtain a high cell concentration. The productivity of immobilized cell fermentation was 16% higher than that of suspended-cell fermentation in batch and it reached a higher value of 4.28 g/l/h in repeated batches. Additionally, using this method, the ethanol yield (95.88%) was found to be higher than that of other tested methods due to low concentrations of residual sugars and free cells. Continuous ethanol production using four bioreactors showed a higher productivity (9.57 g/l/h) and yield (96.96%) with an ethanol concentration of 104.65 g/l obtained from 219.42 g/l of initial total sugar at a dilution rate of 0.092 h-1. Furthermore, we reversed the substrate-feed flow directions in the in-series bioreactors to keep the cells at their highest activity and to extend the length of continuous fermentation. Our study demonstrates an effective method of ethanol production with a new immobilized approach, and that by switching the flow directions, traditional continuous fermentation can be greatly improved, which could have practical and broad implications in industrial applications.

      • Highly Active Iron Oxide Supported Gold Catalysts for CO Oxidation: How Small Must the Gold Nanoparticles Be?

        Liu, Yong,Jia, Chun-Jiang,Yamasaki, Jun,Terasaki, Osamu,Schü,th, Ferdi WILEY-VCH Verlag 2010 Angewandte Chemie. international edition Vol.49 No.33

        <B>Graphic Abstract</B> <P>The shape of gold: The title catalyst has been prepared through a colloidal deposition method. Scanning transmission electron microscopy studies confirmed that for the catalyst, gold clusters with a bilayer structure and a diameter of about 0.5 nm are not mandatory to achieve the high activity (see image). <img src='wiley_img_2010/14337851-2010-49-33-ANIE201000452-content.gif' alt='wiley_img_2010/14337851-2010-49-33-ANIE201000452-content'> </P>

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