Mutual intercropping-inspired co-silanization to graft well-oriented organosilane as adhesion promotion nanolayer for flexible conductors

Yi-Hsuan Chen,Yi-Hsiang Lai,Ping-Heng Wu,Li-Syuan Chen,Yung-Sen Lin,Chih-Ming Chen 한국공업화학회 2020 Journal of Industrial and Engineering Chemistry Vol.83 No.-

Surface metallization of polymer substrate andfilm adhesion are crucial to the development offlexibleelectronics. This study demonstrates the co-silanization engineering on the polyimide (PI)film by mutualintercropping of two organosilane molecules to improve their grafting orientability and enhance theadsorbability toward the PI substrate and loaded metal atoms. The mutual intercropping-inspired cosilanizationengineering is implemented by using 3-[(trimethylsilyl)ethynyl]pyridine (TEP) as asupporting organosilane to spatially confine the grafting orientation of the supported aminosilane, 3-[2-(2-aminoethylamino)ethylamino]propyl-trimethoxysilane (ETAS), leading to the formation of a wellorientedorganosilane composite nanolayer as adhesion promotion layer forflexible conductors. Theflexible Cu conductor electrolessly deposited on the PIfilm by co-silanization shows improved adhesionstrength (0.9 kgf/cm) compared to those based on mono-silanization (0.51 kgf/cm) and sputtered Ta/Cu(0.4 kgf/cm). Superior deformability (bendability) was also achieved for the co-silanized Cu/PI sample byretaining good electrical property after bending cycle up to 1000.

HOW DOES BRAND-SPECIFIC LEADERSHIP INFLUENCE ON EMPLOYEE-BASED BRAND EQUITY?

Yi-Hsuan Lee,Chan Hsiao,Hsin-Yi Chan,I-Chen Lee 글로벌지식마케팅경영학회 2018 Global Marketing Conference Vol.2018 No.07

Brand equity (BE) previously focused on consumers’ perceptions under brand marketing stimuli, they often used financial performance indicators for evaluating brand value (Aaker,1996;Keller,1993). However the primary stakeholders of a service brand are employees (Brexendorf & Kernstock,2007).Thus, the enhancement of employee- based BE could be an important topic for in-depth investigation in the fields of brand and internal marketing. Morhart (2009) was the first to introduce the concepts of brand-specific transformational leadership (TFL) and brand-specific transactional leadership (TRL) based on employees’ brand-building behavior. Theory asserts that leaders should endeavor to influence employees through the internalization of brand values and a brand-based role (Morehart,2001) . In the process of brand internalization, leaders with brand experience and brand knowledge should also uphold and constantly reaffirm brand values because they're more capable than ordinary leaders to clearly convey brand values (Hoffman,1999). For this reason, brand-specific leadership based on employee brand-building behaviors is the focus of this study. This study adopts hierarchical linear modeling for individual and organizational-level analyses. This research to investigate (1)whether TFL and TRL have directly affect employee-based individual-level BE.(2)whether TFL and TRL have indirectly affect employee-based BE as an individual-level mediator.(3)how managers use brand-specific leadership to elicit employees’ perceived brand value congruence for improved employee-based BE.

Does Fear Spill Over?

Cathy Yi-Hsuan Chen 한국증권학회 2014 Asia-Pacific Journal of Financial Studies Vol.43 No.4

This paper develops a new methodology for analyzing fear spillovers between four impliedvolatility indices (MVX in Canada, VXJ in Japan, VDAX in Germany and VIX in the UnitedStates) using a copula-based bivariate Markov-switching model. We consider a parameterizationof the Markov-switching model that allows for four possible states (consisting of combinationsof either low or high expected volatilities). This model also combines selectedcopulas to describe the dependence pattern between different markets. The results show thatdependencies, contagions and causalities between the four implied volatility index levels arestrongly supported by the data in all copulas. From the dynamic and asymmetric analysis,the results indicate that the linkages between implied volatility indices are more pronouncedwhen the indices rise.

Copper recovery via polyelectrolyte enhanced ultrafiltration followed by dithionite based chemical reduction: Effects of solution pH and polyelectrolyte type

Chou, Yi-Hsuan,Choo, Kwang-Ho,Chen, Shiao-Shing,Yu, Jui-Hsuan,Peng, Ching-Yu,Li, Chi-Wang Elsevier 2018 Separation and purification technology Vol.198 No.-

<P><B>Abstract</B></P> <P>A chemical reduction process was proposed to recover copper from the retentate of polyelectrolyte enhanced ultrafiltration (PEUF). Three polyelectrolytes (PSS, PAA, and PEI) containing various functional groups and molecular weights were studied to explore their effects on the copper removal in PEUF and on the copper recovery by chemical reduction under various pH conditions. With PSS which contains sulfonic group, copper was removed reasonably well (ca. 75%) by PEUF even under acidic pH value of 3. With PAA which contains carboxylic group, copper removal was a bit low (∼60%) under pH 3.0 but increased substantially at pH 4.0. A branched PEI having amine group achieved the highest Cu removal of 94% at pH 3. The copper removal efficiency decreased slightly with increasing pH due to the high permeation of PEI through membrane.</P> <P>Chemical reduction achieved the complete copper recovery for solution containing PSS. The copper recovery efficiencies were more than 95% for PAA solution with pH values ranging from 3 to 9 at reaction time of one hour. For PEI, the recovery efficiencies ranged from 20 to 96% and were pH dependent. Aggregated and settled readily copper particles were produced by chemical reduction in PSS solution. XRD analysis identified cuprous oxide in all of the samples. Dependent of pH and polyelectrolytes, additional peaks matching those of elemental copper were identified. TGA analysis showed that solids produced from PSS and PAA systems contained no polyelectrolytes while solid collected from PEI system contained 32% of polyelectrolyte.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Polyelectrolytes with different functional groups and MW were applied in PEUF. </LI> <LI> Effects of polyelectrolytes and pH on the reduction of copper were studied. </LI> <LI> Both Cu<SUB>2</SUB>O and Cu<SUP>0</SUP> were identified by XRD analysis of solids obtained. </LI> </UL> </P>

Risk factor analysis of coexisting endometrial carcinoma in patients with endometrial hyperplasia: a retrospective observational study of Taiwanese Gynecologic Oncology Group

Yu-Li Chen,Kung-Liahng Wang,Min-Yu Chen,Mu-Hsien Yu,Chen-Hsuan Wu,Yu-Min Ke,Yi-Jen Chen,Yin-Yi Chang,Keng-Fu Hsu,Ming-Shyen Yen 대한부인종양학회 2013 Journal of Gynecologic Oncology Vol.24 No.1

Objective: To evaluate the clinical outcome and parameters related to coexisting endometrial carcinoma in women with tissuediagnosed endometrial hyperplasia. Methods: Between January 1991 and December 2009, three hundred and eighty-six patients with the presumptive diagnosis of endometrial hyperplasia were retrieved. Among these, one hundred and twenty-five patients were identified as having coexisting endometrial carcinoma in hysterectomy specimens. The three hundred and eighty-six patients were divided into two groups: the hyperplasia-benign group (261 cases) and the hyperplasia-malignant group (125 cases). Several clinical parameters including age, menopausal status, history of abnormal uterine bleeding, obstetrical history, medical history of diabetes and hypertension, BMI, and preoperative pathologic results were investigated. Results: Age ≥53 (odds ratio [OR], 2.40; 95% confidence interval [CI], 1.26 to 4.57), menopausal status (OR, 2.07; 95% CI, 1.14to 3.76), diabetes history (OR, 7.33; 95% CI, 2.79 to 19.26), abnormal uterine bleeding (OR, 3.99; 95% CI, 1.22 to 13.02), atypical endometrial hyperplasia (OR, 7.38; 95% CI, 4.03 to 13.49), and body mass index ≥27 (OR, 3.24; 95% CI, 1.76 to 5.97) were independent risk factors for prediction of endometrial hyperplasia coexisting with endometrial carcinoma. The diagnostic efficacy of atypical endometrial hyperplasia to predict the endometrial hyperplasia coexisting with endometrial carcinoma was better than or similar to those of other independent factors and combinations of these factors. Conclusion: Coexisting malignancy should be considered when examining endometrial hyperplasia patients with the related risk factors, especially atypical endometrial hyperplasia.

The Association of Acquired T790M Mutation with Clinical Characteristics after Resistance to First-Line Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor in Lung Adenocarcinoma

Yen-Hsiang Huang,Kuo-Hsuan Hsu,Jeng-Sen Tseng,Kun-Chieh Chen,Chia-Hung Hsu,Kang-Yi Su,Jeremy J. W. Chen,Huei-Wen Chen,Sung-Liang Yu,Tsung-Ying Yang,Gee-Chen Chang 대한암학회 2018 Cancer Research and Treatment Vol.50 No.4

Purpose The main objective of this study was to investigate the relationship among the clinical characteristics and the frequency of T790M mutation in advanced epidermal growth factor receptor (EGFR)mutant lung adenocarcinoma patients with acquired resistance after firstline EGFRtyrosine kinase inhibitor (TKI) treatment. Materials and Methods We enrolled EGFR-mutant stage IIIB-IV lung adenocarcinoma patients, who had progressed to prior EGFR-TKI therapy, and evaluated their rebiopsy EGFRmutation status. Results A total of 205 patients were enrolled for analysis. The overall T790M mutation rate of rebiopsy was 46.3%. The T790M mutation rates among patients with exon 19 deletion mutation, exon 21 L858R point mutation, and other mutations were 55.0%, 37.3%, and 27.3%, respectively. Baseline exon 19 deletion was associated with a significantly higher frequency of T790M mutation (adjusted odds ratio, 2.14; 95% confidence interval [CI], 1.20 to 3.83; p=0.010). In the exon 19 deletion subgroup, there was a greater prevalence of T790M mutation than other exon 19 deletion subtypes in patients with the Del E746-A750 mutation (61.6% vs. 40.6%; odds ratio, 2.35; 95% CI, 1.01 to 5.49; p=0.049). The progression- free survival (PFS) of first-line TKI treatment > 11 months was also associated with a higher T790M mutation rate (54.1% vs. 39.3%; adjusted odds ratio, 1.82; 95% CI, 1.02 to 3.25; p=0.044). Patients who underwent rebiopsy at metastatic sites had more chance to harbor T790M mutation (52.6% vs. 33.8%; adjusted odds ratio, 1.97; 95% CI, 1.06 to 3.67; p=0.032). Conclusion PFS of first-line EGFR-TKI, rebiopsy site, EGFR exon 19 deletion and its subtype Del E746- A750 mutation are associated with the frequency of T790M mutation.

Factors Influencing Intention to Receive Examination of Diabetes Complications

Yi-Lin Hsieh,Fang-Hsin Lee,Chien-Liang Chen,Ming-Fong Chang,Pei-Hsuan Han 한국간호과학회 2016 Asian Nursing Research Vol.10 No.4

Purpose: The purpose of this study was to understand the situation of diabetes patients receiving examinations for diabetes complications and to explore the factors influencing their intention to receive examinations for diabetes complications. Methods: A cross-sectional study was performed that included 251 diabetes patients who visited outpatient clinics in Southern Taiwan. A survey using a self-administered questionnaire was conducted from October 2015 to January 2016. The questionnaire included items on demographic characteristics, perceived susceptibility to diabetes complications, perceived seriousness of diabetes complications, perceived benefits of taking action to receive diabetes complication examinations, perceived barriers to taking action to receive diabetes complication examinations, and the intention to receive diabetes complication examinations. The data were analyzed using regression analysis. Results: The percentage of participants who received fundus, foot, and kidney examinations was 67.7%, 61.4%, and 73.3%, respectively. Every point increase on the perceived barriers to taking action to receive diabetes complication examinations scale increased the intention to receive a foot examination in the following year by 0.91 times (p = .002), and every point increase on the perceived susceptibility to diabetes complications scale increased the intention to receive a kidney examination in the following year by 1.19 times (p = .045). Conclusions: Nurses should shoulder the responsibility to increase patients' intention to receive examination of diabetes complications. The results of this study can be used to promote nurses' care efficacy in preventing diabetes complications. They can also provide medical institutions with information to establish prevention and control policies for diabetes complications.

Three-Level Bi-Directional Half-Bridge CLLC Resonant Converter for DC Micro-Grid

Hsuan-Yu Yueh,Jing-Yuan Lin,Haung-Jen Chiu,Chen-Yen Chu,Yu-Chen Chang,Sih-Yi Lee 전력전자학회 2019 ICPE(ISPE)논문집 Vol.2019 No.5

A Three-Level Bi-Directional Half-Bridge CLLC Resonant DC-DC converter for DC micro-grid application is studied on this paper, which uses dual resonant tanks to achieve wide range voltage regulation and meanwhile employs bi-directional capability. All power switches on this converter can achieve ZVS function at the whole load and the voltage stress on all power switches at both sides can be clamped at half of input voltage and output voltage since the three-level circuit architecture using the proposed synchronous rectifier (SR) control, therefore, the voltage stresses of the transformer, resonant tanks, power switches and other components are only half compared with conventional half-bridge CLLC resonant converter, the downsizing rated of components selection can be more flexible. Finally, the laboratory prototype is built to verify the performance of voltage balancing on input/output capacitor, voltage stress on switches and efficiency, the measured efficiency can be up to 95.6% over different load conditions.

Identification of differential DNA methylated regions between different development of entomopathogenic fungi, Beauveria bassiana NCHU-157, by Nanopore sequencing

Yi-Hsuan Li,Ju-Chun Chang,Ming-Ren Yen,Yu-Feng Huang,Tzu-Han Chen,Yu-Shin Nai 한국응용곤충학회 2022 한국응용곤충학회 학술대회논문집 Vol.2022 No.10

A Genetic Analysis of Taoyuan Pig and Its Phylogenetic Relationship to Eurasian Pig Breeds

Kuan-Yi Li,Kuang-Ti Li,Chun-Chun Cheng,Chia-Hsuan Chen,Chien-Yi Hung,Yu-Ten Ju 아세아·태평양축산학회 2015 Animal Bioscience Vol.28 No.4

Taoyuan pig is a native Taiwan breed. According to the historical record, the breed was first introduced to Taiwan from Guangdong province, Southern China, around 1877. The breed played an important role in Taiwan’s early swine industry. It was classified as an indigenous breed in 1986. After 1987, a conserved population of Taoyuan pig was collected and reared in isolation. In this study, mitochondrial DNA sequences and 18 microsatellite markers were used to investigate maternal lineage and genetic diversity within the Taoyuan pig population. Population differentiation among Taoyuan, Asian type, and European type pig breeds was also evaluated using differentiation indices. Only one D-loop haplotype of the Taoyuan pig was found. It clustered with Lower Changjiang River Basin and Central China Type pig breeds. Based on the polymorphism of microsatellite markers, a positive fixation index value (FIS) indicates that the conserved Taoyuan population suffers from inbreeding. In addition, high FST values (>0.2105) were obtained, revealing high differentiation among these breeds. Non-metric multi-dimensional scaling showed a clear geometric structure among 7 breeds. Together these results indicate that maternally Taoyuan pig originated in the Lower Changjiang River Basin and Central China; however, since being introduced to Taiwan differentiation has occurred. In addition, Taoyuan pig has lost genetic diversity in both its mitochondrial and nuclear genomes.