http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
오늘 본 자료
Xinyu Cao,Yin Fang,Chunguang Yang,Zhenghao Liu,Guoping Xu,Yan Jiang,Peiyan Wu,Wenbo Song,Hanshuo Xing,Xinglong Wu 대한배뇨장애요실금학회 2024 International Neurourology Journal Vol.28 No.1
Purpose: Prostate cancer (PCa) is an epithelial malignancy that originates in the prostate gland and is generally categorized into low, intermediate, and high-risk groups. The primary diagnostic indicator for PCa is the measurement of serum prostate-specific antigen (PSA) values. However, reliance on PSA levels can result in false positives, leading to unnecessary biopsies and an increased risk of invasive injuries. Therefore, it is imperative to develop an efficient and accurate method for PCa risk stratification. Many recent studies on PCa risk stratification based on clinical data have employed a binary classification, distinguishing between low to intermediate and high risk. In this paper, we propose a novel machine learning (ML) approach utilizing a stacking learning strategy for predicting the tripartite risk stratification of PCa. Methods: Clinical records, featuring attributes selected using the lasso method, were utilized with 5 ML classifiers. The outputs of these classifiers underwent transformation by various nonlinear transformers and were then concatenated with the lasso-selected features, resulting in a set of new features. A stacking learning strategy, integrating different ML classifiers, was developed based on these new features. Results: Our proposed approach demonstrated superior performance, achieving an accuracy of 0.83 and an area under the receiver operating characteristic curve value of 0.88 in a dataset comprising 197 PCa patients with 42 clinical characteristics. Conclusions: This study aimed to improve clinicians’ ability to rapidly assess PCa risk stratification while reducing the burden on patients. This was achieved by using artificial intelligence-related technologies as an auxiliary method for diagnosing PCa.
Xylazole inhibits NO-cGMP pathway in fetal rat nerve cells
Xinyu Wang,Yue Wu,Lin Liu,Hui Bai,Zhiheng Zhang,Mingchao Zhao,Tianwen Ma,Xiaopeng Song,Lina Jia,Liangyu Lv,Yue Yu,Xinyu Xu,Hong Chen,Li Gao 대한수의학회 2022 Journal of Veterinary Science Vol.23 No.1
Background: Xylazole (Xyl) is a veterinary anesthetic that is structurally and functionally similar to xylazine. However, the effects of Xyl in vitro remain unknown. Objectives: This study aimed to investigate the anesthetic mechanism of Xyl using fetal rat nerve cells treated with Xyl. Methods: Fetal rat nerve cells cultured for seven days were treated with 10, 20, 30, and 40 μg/ mL Xyl for 0, 5, 10, 15, 20, 25, 30, 45, 60, 90, and 120 min. Variations of amino acid neurotransmitters (AANTs), Nitric oxide-Cyclic GMP (NO-cGMP) signaling pathway, and ATPase were evaluated. Results: Xyl decreased the levels of cGMP and NO in nerve cells. Furthermore, Xyl affected the AANT content and Na+-K+-ATPase and Ca2+-Mg2+-ATPase activity in nerve cells. These findings suggested that Xyl inhibited the NO-cGMP signaling pathway in nerve cells in vitro. Conclusions: This study provided new evidence that the anesthetic and analgesic effects of Xyl are related to the inhibition of the NO-cGMP signaling pathway.
Microwave-assisted modification of activated carbon with ammonia for efficient pyrene adsorption
Xinyu Ge,Zhansheng Wu,Zhilin Wu,Yujun Yan,Giancarlo Cravotto,Bang-Ce Ye 한국공업화학회 2016 Journal of Industrial and Engineering Chemistry Vol.39 No.-
With the aim to enhance the adsorption properties of polycyclic aromatic hydrocarbons (PAHs) fromaqueous solutions, coal-based activated carbon (CAC) was modified with three different protocols: (i)ammonia treatment (A-CAC), (ii) microwave radiation (M-CAC) (iii) and combined microwave radiationin the presence of ammonia (MA-CAC). The original CAC and all the modified samples were characterizedby SEM, nitrogen adsorption–desorption, Boehm method, point of zero charge, FTIR and XPS. The surfacearea increased from 764.96 to 1293.78 m2/g for CAC and MA-CAC, whereas the total oxygen-containinggroups decreased from 1.57 to 0.25 mmol/g. The pyrene adsorption capacity of all the modified sampleswas higher than CAC and the adsorption process for pyrene to the equilibrium needed only 40 min. Adsorption of pyrene on CAC and MA-CAC varies from the monolayer to multilayer process. The filmdiffusion could control the adsorption rate of pyrene onto carbons. The adsorption capacity of the CACand modified samples had a good positive correlation with surface area, carboxyl groups, and lactonesgroups. The modified samples, especially MA-CAC, showed an enhanced adsorption of pyrene openingthe way to a more general application as efficient adsorbent for PAHs contaminant.
( Xinyue Chang ),( Chengli Teng ),( Haizhen Wu ),( Jiang Ye ),( Qiyao Wang ),( Huizhan Zhang ) 한국미생물생명공학회(구 한국산업미생물학회) 2019 Journal of microbiology and biotechnology Vol.29 No.8
Edwardsiella piscicida is the causative agent of edwardsiellosis, which has caused enormous economic losses worldwide. In our previous research, an attenuated live vaccine known as WED and based on the virulent strain E. piscicida EIB202 can effectively protect turbots against edwardsiellosis via intraperitoneal injection, while vaccination by immersion exhibits a weaker effect. During the development of the immersion vaccine, we surprisingly found the counts of ΔpEIB202/ EIB202 colonized on zebrafish were 100 times lower than those of EIB202. However, pEIB202 carries 53 predicted ORFs and has several copies in E. piscicida EIB202, impeding the study of its function. Thus, the replication region is located at a 1,980 bp fragment (from 18,837 to 20,816 bp), containing a transcriptional repressor and a replication protein. Moreover, the minimal replication plasmid, named pRep-q77, has low copies in both E. coli and E. piscicida, but is more stable in E. piscicida than in E. coli. This work lays a foundation for further examination of the function of the virulence plasmid pEIB202.
Xinyu Zhu,Xiao Liang,Kaiyue Gong,Xu Peng,Jun Cai,Xiaohan Liu,Chao Zhou,Siqi An,Chao Wu,Pengcheng Han 전력전자학회 2022 JOURNAL OF POWER ELECTRONICS Vol.22 No.12
As a vital component of power electronic transformers (PET), the reliability of a cascaded H-bridge rectifier (CHBR) is essential. Therefore, in this paper, a DC-port voltage balance strategy considering DC-port failure is researched to ensure the stable operation of a CHBR. However, if the DC-port voltage balance strategy is adopted to realize the single-phase balance of a CHBR, the three-phase currents become unbalanced. This paper uses a negative sequence control (NSC) strategy that is conducive to balancing DC-port voltage to achieve three-phase current balance. For the DC-port voltage balance, the matrix generation modulation (MGM) algorithm is proposed. In addition, the DC-port voltage balance boundary is analyzed to determine the range of the DC-port voltage balance in the CHBR. A 3-module cascading topology is adopted to demonstrate the MGM algorithm and the NSC strategy. Through experiments, results show the correctness and feasibility of the proposed strategy.
Wu, Jing,Tan, Xinyu,Peng, Xiaozhong,Yuan, Jiangang,Qiang, Boqin Korean Society for Biochemistry and Molecular Biol 2003 Journal of biochemistry and molecular biology Vol.36 No.4
For better understanding of functions of the Calcyclin Binding Protein (CacyBP) and exploring its possible roles in neuronal differentiation, the subcellular localization of human CacyBP was examined in retinoic acid(RA)-induced and uninduced neuroblastoma SH-SY5Y cells. Immunostaining indicated that CacyBP was present in the cytoplasm of uninduced SH-SY5Y cells, in which the resting $Ca^{2+}$ concentration was relatively lower than that of RA-induced cells. After the RA induction, immunostaining was seen in both the nucleus and cytoplasm. In the RA-induced differentiated SH-SY5Y cells, CacyBP was phosphorylated on serine residue(s), while it existed in a dephosphorylated form in normal (uninduced) cells. Thus, the phosphorylation of CacyBP occurs when it is translocated to the nuclear region. The translocation of CacyBP during the RA-induced differentiation of SH-SY5Y cells suggested that this protein might play a role in neuronal differentiation.
Structural behaviors of sustainable hybrid columns under compression and flexure
Wu Xiang-Guo,Hu Qiong,Zou Ruofei,Zhao Xinyu,Yu Qun 국제구조공학회 2014 Structural Engineering and Mechanics, An Int'l Jou Vol.52 No.5
Structural behaviors of a sustainable hybrid column with the ultra high performance cementitious composites (UHPCC) permanent form under compression and flexure were studied. Critical state and failure stage characters are analyzed for large and small eccentricity cases. A simplified theoretical model is proposed for engineering designs and unified formulas for loading capacity of the hybrid column under compression and flexure loads are derived, including axial force and moment. Non-linear numerical analysis is carried out to verify the theoretical predictions. The theoretical predictions agree well with the numerical results which are verified by the short hybrid column tests recursively. Compared with the traditional reinforced concrete (RC) column, the loading capacity of the sustainable hybrid column is improved significantly due to UHPCC confinements.
사회적 상호작용을 증진시키는 지하 공공공간 디자인을 위한 사용자 행태연구 - 부산역의 지하공간을 중심으로 사례연구 -
오거붕(Wu, JuPeng),장신웨(Zhang, XinYue),박수빈(Park, Soo-Ben) 한국주거학회 2023 한국주거학회 학술대회논문집 Vol.35 No.1
This study investigates the rest area and the transfer access area of Busan Station, Line 1 of the urban subway in Busan, Korea, and grasps the morphology of people in the two areas. Based on the current situation and behavior of people using the spaces, the study proposes improvement plans for the subsequent design of the spaces. This study was conducted through on-site observation surveys. The main findings include that there is no major difference in people’s use of space between midweek and weekend. Among the morning and afternoon time periods, the frequency of use was higher in the afternoon than in the morning. Among the types of behaviors, in addition to the basic walking behavior, there were also small behaviors that, although small in number, would make the space more convenient for those using it if the furniture or design elements in the space were slightly changed.
지하철 역사 내 유도사인시스템 색채 특성에 관한 연구 - 부산시 2개 환승역을 대상으로 -
오거붕(Wu Jupeng),장신웨(Zhang Xinyue),박수빈(Park, Sooben) 대한건축학회 2022 대한건축학회 학술발표대회 논문집 Vol.42 No.2
The number of subway users has increased every year, making it one of the most popular means of transportation. This study aims to investigate the color uses of the subway guidance sign system and propose a color control creteria for guidance signs in subway stations. A field study was conducted on the transfer stations of Seomyeon Station and Deokcheon Station located in Busan. The process uncluds taking pictures of guidance signs using spydercube for the white balance and selecting and converting main colors of the on into NCS. The color uses of each guidance signs were analyzed and compared by guidance sign types.
Huiqiang Wu,Xiangmin Wang,Yang Liu,Yu Zhao,Xinyue Wang,Woo-Kyoung Lee,심영기,Il Yoon,Xinming Xu,Jiazhu Li 대한화학회 2020 Bulletin of the Korean Chemical Society Vol.41 No.5
In this article, we report the stereoselective Horner?Wadsworth?Emmons reaction of reactive carbonyl-substituted chlorophyll a derivatives with diethyl cyanomethylphosphonate. We found that the formyl or keto group at the chlorin periphery can react stereoselectively with phosphonate carbanions to produce a series of cyanomethylene-substituted chlorins with predominantly E geometry. Considering that no consistent records are available in the literature on the results of the allomerization of methyl pyropheophorbide a, we propose a reliable process for the transformation of this chlorophyll derivative. Our methodology represents a simple and efficient way for the preparation of novel, differently functionalized long-wavelength absorbing chlorins, those can be applied for photodynamic therapy, solar cells, and other relevant purposes.