Negative sequence control for DC voltage balancing in three‑phase cascaded H‑bridge rectifiers considering DC‑port failures

Xinyu Zhu,Xiao Liang,Kaiyue Gong,Xu Peng,Jun Cai,Xiaohan Liu,Chao Zhou,Siqi An,Chao Wu,Pengcheng Han 전력전자학회 2022 JOURNAL OF POWER ELECTRONICS Vol.22 No.12

As a vital component of power electronic transformers (PET), the reliability of a cascaded H-bridge rectifier (CHBR) is essential. Therefore, in this paper, a DC-port voltage balance strategy considering DC-port failure is researched to ensure the stable operation of a CHBR. However, if the DC-port voltage balance strategy is adopted to realize the single-phase balance of a CHBR, the three-phase currents become unbalanced. This paper uses a negative sequence control (NSC) strategy that is conducive to balancing DC-port voltage to achieve three-phase current balance. For the DC-port voltage balance, the matrix generation modulation (MGM) algorithm is proposed. In addition, the DC-port voltage balance boundary is analyzed to determine the range of the DC-port voltage balance in the CHBR. A 3-module cascading topology is adopted to demonstrate the MGM algorithm and the NSC strategy. Through experiments, results show the correctness and feasibility of the proposed strategy.

Manufacturing Principle and Meshing Limit Line of Toroidal Surface Enveloping Cylindrical Worm Drive with Arc-Toothed Worm

Xinyue Zhu,Yaping Zhao,Yifei Chi,Gongfa Li,Xinyuan Chen 한국정밀공학회 2022 International Journal of Precision Engineering and Vol.23 No.3

The main purpose of this article is to determine the processing parameters of the worm and establish the theory of the meshing limit line of toroidal surface enveloping cylindrical worm drive with the arc-toothed worm. Based on this condition that the instantaneous contact line is a planar curve during grinding the worm blank, it can be deduced that its torsion is equal to zero, then the formulae which determine the installing position of the grinding wheel are acquired. Following this, the equations of the tooth surfaces and the meshing limit function are all obtained. According to the geometric construction and elimination method, the meshing limit points are determined by iteratively solving the corresponding nonlinear equation in its solution domain. In addition, the result of the numerical case demonstrates that the worm helicoid is divided into two parts by the meshing limit line, which makes the working length of the worm cannot reach half of its total thread length. And by adjusting the design parameters of the worm pair and the processing parameters of the worm, the meshing limit line cannot be eliminated and its position on the surfaces of the worm and the worm gear has no notable change.

Evolution of plant Ash1 SET genes: structural divergence and functional differentiation

Xinyu Zhu,Baohua Wang,Xianzhao Kan,Caoyi Chen,Chunmei Yu 한국유전학회 2013 Genes & Genomics Vol.35 No.4

Plant Ash1 SET proteins are involved in H3K36methylation, and play a key role in plant reproductive development. Genes encoding Ash1 SET proteins constitute a multigene family in which the copy number varies among plant species and functional divergence appears to have occurred repeatedly. To investigate the evolutionary history and functional differentiation of the Ash1 SET gene family,we made a comprehensive evolutionary analysis of this gene family from eleven major representatives of green plants. A novel deep sister relationship grouping previously resolved II-1 and II-2 orthologous groups was identified. The absence of AWS domain in the group II-2 suggests that the independent losses of AWS domain have occurred during evolution. A diversity of gene structures in plant Ash1 SET gene family have been presented since the divergence of Physcomitrella patens (moss) from the other land plants. A small proportion of codons in SET domain regions were detected to be under positive selection along the branches ancestral to land plant and angiosperms, which may have allowed changes of substrate specificity among different evolutionary groups while maintaining the primary function of SET domains. Our predictive subcellular localization and comparative anatomical meta-expression analyses can assort with the structural divergences of Ash1SET proteins.

Water-blocking Asphyxia of N95 Medical Respirator During Hot Environment Work Tasks With Whole-body Enclosed Anti-bioaerosol Suit

Zhu Jintuo,Jiang Qijun,Ye Yuxuan,He Xinjian,Shao Jiang,Li Xinyu,Zhao Xijie,Xu Huan,Hu Qi 한국산업안전보건공단 산업안전보건연구원 2023 Safety and health at work Vol.14 No.4

Background: During hot environment work tasks with whole-body enclosed anti-bioaerosol suit, the combined effect of heavy sweating and exhaled hot humid air may cause the N95 medical respirator to saturate with water/sweat (i.e., water-blocking). Methods: 32 young male subjects with different body mass indexes (BMI) in whole-body protection (N95 medical respirator + one-piece protective suit + head covering + protective face screen + gloves + shoe covers) were asked to simulate waste collecting from each isolated room in a seven-story building at 27-28°C, and the weight, inhalation resistance (Rf), and aerosol penetration of the respirator before worn and after water-blocking were analyzed. Results: All subjects reported water-blocking asphyxia of the N95 respirators within 36-67 min of the task. When water-blocking occurred, the Rf and 10-200 nm total aerosol penetration (Pt) of the respirators reached up to 1270-1810 Pa and 17.3-23.3%, respectively, which were 10 and 8 times of that before wearing. The most penetration particle size of the respirators increased from 49-65 nm before worn to 115-154 nm under water-blocking condition, and the corresponding maximum size-dependent aerosol penetration increased from 2.5-3.5% to 20-27%. With the increase of BMI, the water-blocking occurrence time firstly increased then reduced, while the Rf, Pt, and absorbed water all increased significantly. Conclusions: This study reveals respirator water-blocking and its serious negative impacts on respiratory protection. When performing moderate-to-high-load tasks with whole-body protection in a hot environment, it is recommended that respirator be replaced with a new one at least every hour to avoid water-blocking asphyxia.

Phenolic features and anthocyanin profiles in winemaking pomace and fresh berries of grapes with different pedigrees

Lei Zhu,Xin Wu,Xixi Hu,Xinyue Li,Shanshan Lv,Chuan Zhan,Yunhua Chen,Changyuan Wang,Jingyu Xu 한국식품과학회 2023 Food Science and Biotechnology Vol.32 No.2

The total contents and antioxidant activities of phenolic compounds as well as anthocyanin profiles were analyzed and compared in fresh berries and fermented pomace of three grape cultivars with different pedigrees. The phenolic contents and antioxidant activities decreased significantly in skins (p < 0.05), while relatively large amounts of them were retained in seeds after fermentative maceration. Fermentative maceration also had a significant impact on the anthocyanin compositions. The proportions of anthocyanins with more stable structures, such as malvidin derivatives, methylated, diglucosides and nonacylated anthocyanins, increased significantly in the pomace skins (p < 0.05). There were obvious differences in phenolic features and anthocyanin profiles among the three cultivars. ‘NW196’, a wine hybrid of Vitis vinifera and V. quinquangularis, was characterized by the highest total anthocyanin contents and degree of diglucosylation. The results obtained in this study could contribute to the primary data for the development and utilization of winemaking pomace, especially from local non-Vitis vinifera grapes.

Characterization and utilization of a cytoplasmic male sterility line of Wucai (Brassica campestris L.)

Guohu Chen,Xinyu Ye,Fanli Zeng,Jian Wang,Lingyun Yuan,Shidong Zhu,Jinfeng Hou,Yuan Cheng,Chenggang Wang 한국원예학회 2019 Horticulture, Environment, and Biotechnology Vol.60 No.3

The novel male sterility line 12-14A of Wucai ( Brassica campestris ) was generated by backcrossing. In this study, morphological,molecular, and cytological analyses were performed to characterize this line. The phenotypes of fl ower organsof 12-14A were diff erent from those of its maintainer line 12-14B, as the fl owers of 12-14A were completely infertile. Molecular analysis confi rmed that the male sterility line 12-14A was classifi ed as the ogu CMS type. An analysis of antherdevelopment in the CMS line demonstrated that two types of abortion occur simultaneously: pollen mother cell abortionand tetrad-to-mononuclear microspore abortion. In addition, the mature anthers of 12-14A showed typical abortive features,such as appearing dry, shrunken, and scaly. A heterosis test of hybrids from CMS 12-14A and four inbred lines was carriedout, and the F 1 hybrids exhibited clear heterosis in plant weight, as well as in the protein, soluble sugar, and vitamin C content,suggesting high yields and high quality potential. These results indicate that this novel CMS line may have powerfulpotential in Wucai hybrid breeding.

SIMULATING TIRE INFLATION PRESSURE LOSS RATE TEST BY THE IDEAL MATERIAL METHOD

Chen Liang,Xinyu Zhu,Changda Li,Guolin Wang,Liu Ji 한국자동차공학회 2019 International journal of automotive technology Vol.20 No.4

Tire Inflation Pressure Loss Rate (IPLR) test is a widely accepted test method to evaluate the tire pressure retention performance, which helps increase fuel economy and prevent premature tire failures. At present, an IPLR test usually lasts for several months, which greatly reduces the efficiency of relevant research. Several analytical models are available to estimate the IPLR value, however, it mainly considers the gauge and permeability of innerliner, ignoring the effect of other components and detailed tire structure. In order to perform a thorough study of tire pressure loss process, a finite element model was developed with the material input of both mechanical and permeability properties of various rubber compounds and tire geometry input. A creative method, ideal material method, was proposed to describe the transient pressure loss process. Through this solution, a finite element model of Passenger Car Radial tire is established to predict IPLR, with a difference from the experimental result less than 5 %. Based on the model, air diffusion path in the tire is studied to better understand the process, which explains the bubble location in tire immersion tests. The effect of innerliner parameters, including halobutyl content, gauge and ending length of innerliner, on IPLR has been investigated based on simulation models.

Transition Mechanism from Brittle Fracture to Ductile Shear when Machining Brittle Materials with an Abrasive Waterjet

Huang, Chuanzhen,Zhu, Hongtao,Lu, Xinyu,Li, Quanlai,Che, Cuilian Korean Society for Precision Engineering 2008 International Journal of Precision Engineering and Vol.9 No.2

Critical erosion kinetic energy models for radial/median cracks and lateral cracks in a workpiece are established in this study. We used experimental results to demonstrate that the fracture erosion resistance and erosion machining number could be used to evaluate the brittle fracture resistance and machinability of a workpiece. Erosion kinetic energy models were developed to predict brittle fracture and ductile shear, and a critical erosion kinetic energy model was developed to predict the transition from brittle fracture to ductile shear. These models were verified experimentally.

Molecular profile-based recommendations for postoperative adjuvant therapy in early endometrial cancer with high-intermediate or intermediate risk: a Chinese randomized phase III trial (PROBEAT)

Yang Liu,Changkun Zhu,Hongyu Xie,Yaxia Chen,Weiguo Lv,Xing Xie,Xinyu Wang 대한부인종양학회 2023 Journal of Gynecologic Oncology Vol.34 No.2

Background: The use of molecular categorisation is shifting paradigm towards the use of molecular information to refine risk stratification in endometrial cancer (EC). To date, evidence to support molecular-guided therapies is limited to retrospective studies and secondary molecular analyses of patients receiving standard treatment. The PROBEAT study is the first randomized phase III trial to evaluate tailored adjuvant treatment based on WHO-endorsed molecular classification in Chinese EC patients. It is expected to provide a clinical decision-making tool for adjuvant treatment of patients with high-intermediate risk (HIR) or intermediate risk (IR) EC to better optimise and personalise patient care and increase relapse-free survival. Methods: The PROBEAT trial is a prospective, multicentre study led by Women’s Hospital of Zhejiang University Gynaecologic Oncology Group. Recruitment started on January 24, 2022, and 590 patients with HIR or IR endometrioid EC are expected to be recruited from 13 clinical centres in China. All tumor tissues will be classified into four molecular subtypes (POLEmut, MMRd, p53abn, or NSMP) based on WHO-endorsed molecular classification. Patients will be randomly assigned at a 2:1 ratio to either experimental arm and will receive molecular profile-based adjuvant treatment (observation in the POLEmut subgroup, vaginal brachytherapy in the MMRd or NSMP subgroup, or chemoradiotherapy in the p53abn subgroup) or to standard arm and will receive preferred adjuvant radiotherapy as recommended by the recent National Comprehensive Cancer Network guidelines version 1 (2022). The primary outcome is 3-year rates of recurrence. Secondary outcomes are relapse-free survival, overall survival, adverse events and health-related cancer-specific quality of life.

Molecular characterization and expression of suppressor of cytokine signaling (SOCS) 1, 2 and 3 under acute hypoxia and reoxygenation in pufferfish, Takifugu fasciatus

Dan Wang,Xin Wen,Xinyu Zhang,Yadong Hu,Xinru Li,Wenxu Zhu,Tao Wang,Shaowu Yin 한국유전학회 2018 Genes & Genomics Vol.40 No.11

Hypoxia seriously affects the innate immune system of fish. However, the roles of suppressor of cytokine signaling (SOCS), pivotal anti-inflammatory genes, in response to hypoxia/reoxygenation remain largely unexplored. The primary objective of this study was to elucidate the function of SOCS genes under acute hypoxia and reoxygenation in pufferfish (Takifugu fasciatus). In the present study, SOCS1, 2 and 3 were identified in T. fasciatus referred to as TfSOCS1, 2 and 3. Then, qRTPCR and western blot analysis were employed to assess their expressions at both the mRNA and protein levels. Tissue distribution demonstrated that the three SOCS genes were predominantly distributed in gill, brain and liver. Under hypoxia challenge (1.63 ± 0.2 mg/L DO for 2, 4, 6 and 8 h), the expressions of TfSOCS1 and 3 in brain and liver at the mRNA and protein levels were significantly decreased, while their expressions showed an opposite trend in gill. Different from the expressions of TfSOCS1 and 3, the expression of TfSOCS2 was inhibited in gill, along with its increased expression in brain and liver. After normoxic recovery (7.0 ± 0.3 mg/L of DO for 4 and 12 h), most of TfSOCS genes were significantly altered at R4 (reoxygenation for 4 h) and returned to the normal level at R12 (reoxygenation for 12 h). SOCS genes played vital roles in response to hypoxia/reoxygenation challenge. Our findings greatly strengthened the relation between innate immune and hypoxia stress in T. fasciatus.