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( Jin Nyoung Kim ),( Kyoung Min Sohn ),( Moon Young Kim ),( Ki Tae Suk ),( Soung Won Jeong ),( Ho Eun Jung ),( Sae Hwan Lee ),( Sang Gyune Kim ),( Jae Young Jang ),( Young Seok Kim ),( Soon Koo Baik ) 대한간학회 2012 Clinical and Molecular Hepatology(대한간학회지) Vol.18 No.4
Background/Aims: Variceal hemorrhage is one of the major complications of cirrhosis and is associated with significant mortality and morbidity. The development of gastroesophageal varices and variceal hemorrhage is the most direct consequence of portal hypertension. Correlations between the hepatic venous pressure gradient (HVPG) and first variceal hemorrhage were examined. Methods: Patients with cirrhosis who underwent HVPG measurement between July 2009 and September 2010 were enrolled (n=535). All patients underwent esophagogastroduodenoscopy to enable the evaluation of gastroesophageal varices. Results: The HVPG for all patients was 16.46±7.05 mmHg (mean±SD), and was significantly higher among those with first variceal hemorrhage than in those without it. The HVPG was significantly correlated with both Child-Turcotte-Pugh (r=0.488, P<0.001) and Model for End-stage Liver Disease (r=0.478, P<0.001) scores. An HVPG value of 11 mmHg was predictive of first variceal hemorrhage with a sensitivity of 92.4% and a specificity of 27.7%. Conclusions: The HVPG was higher in patients with first variceal hemorrhage than in those without it. (Clin Mol Hepatol 2012;18:391-396)
간동맥 화학색전술에 의한 간세포암종 크기 감소 이후 간절제술을 시행한 환자
민슬기 ( Seul Ki Min ),김상균 ( Sang Gyune Kim ),김영석 ( Young Seok Kim ),이세환 ( Sae Whan Lee ),정승원 ( Soung Won Jeong ),장재영 ( Jae Young Jang ),김홍수 ( Hong Soo Kim ),김부성 ( Boo Sung Kim ) 대한간암학회 2011 대한간암학회지 Vol.11 No.1
Hepatocellular carcinoma (HCC) is the third most common cancer in korean population. Surgical management is the mainstay of HCC. Surgical resection and liver transplantation shows the best outcomes in well-selected patients. But few patients are possible to benefit from surgical resection or liver transplantation. The majority of cases of HCC are unresectable, but there are no proven treatment modalities for these cases. In small number of articles showed the favorable result of adjuvant chemotherapy, and transcatheter arterial chemoembolization (TACE) for unresectable HCCs. But there are some drawbacks, such as small number of sample size and variablity of study design at each studies. Hereby we report a patients of HCC, who was performed hepatectomy after tumor down sizing with TACE.
위 정맥류 출혈에 대한 내시경적 정맥류 폐색술, 내시경적 정맥류 결찰술, 역행성 경정맥 위정맥류 폐색술 간의 치료효과 비교
김부성 ( Boo Sung Kim ),박재우 ( Park jae woo ),민슬기 ( Seul Ki Min ),김상균 ( Sang Gyune Kim ),김영석 ( Young Seok Kim ),배준용 ( Jun Yong Bae ),이종찬 ( Jong Chan Lee ),김홍수 ( Hong Soo Kim ),정승원 ( Soung Won Jeong ),장재영 대한소화기학회 2011 대한소화기학회지 Vol.57 No.5
Background/Aims: Endoscopic variceal obliteration (EVO), endoscopic variceal ligation (EVL), and balloon-occluded retrograde transvenous obliteration (BRTO) are used to manage gastric variceal bleeding. We compared the re-bleeding rates and survival times of these modalities. Methods: The study enrolled 103 patients with suspected gastric variceal bleeding between July 2001 and May 2009. For the management of gastric variceal bleeding, 52 patients underwent EVO; 36, EVL; and 15, BRTO. We evaluated their laboratory results and vital signs, and calculated the Child score, Child classification, and Model for End-stage Liver Disease score. Rebleeding was defined as new-onset hematemesis, hematochezia, melena, or endoscopically proven bleeding. Time-to-rebleeding and survival time were examined by Kaplan-Meyer analysis. A value of p<0.05 indicated statistical significance. Results: There were no significant differences in baseline characteristics among the three groups. The overall follow-up period averaged 65.13 months. During follow-up, rebleeding occurred in 17 patients (11 EVO, 5 EVL, and 1 BRTO). The times-to-rebleeding were 63.59, 75.79, and 51.41 months for EVO, EVL, and BRTO, respectively, and did not differ significantly (p=0.515). The median survival times were 77.42, 70.14, and 42.79 months, respectively, and also were not different significantly (p=0.978). Conclusions: There were no significant differences in the time-to-rebleeding or survival time among EVO, EVL, and BRTO. Further prospective, large-scale studies are needed. (Korean J Gastroenterol 2011;57:302-308)
( Ki Taek Lim ),( Chong Su Cho ),( Yun Hoon Choung ),( Hoon Seon Woo ),( Hyun Mok Son ),( Soo Jung Baik ),( Jang Ho Kim ),( Sung Min Hong ),( Joo Young Park ),( Soung Hoo Jeon ),( Pill Hoon Choung ),( 한국조직공학·재생의학회 2009 조직공학과 재생의학 Vol.6 No.14
We have developed and evaluated a novel perfusion flow bioreactor system which facilitates the observation of living cells for extended periods of time. Cell viability showed that cell growth rate cultured (without medium perfusion) using the novel flow perfusion chamber system revealed a similar trend (p>0.05) compared to that of static culture. Also, the cell viability under the static culture (without perfusion) and flow perfusion culture (flow rate: 0.03 ml/min) with the developed perfusion bioreactor system was compared. The cell growth rate of the flow perfusion culture was significantly higher (p<0.05) than that of static culture for 4 days. The cell growth rate was efficiently increased to about 10-15% with the precision perfusion culture. These results indicate that a bioreactor system that can provide mechanical signals has important applications. Additionally, the developed cell culture chamber system has been successfully used to maintain and record the morphology of cultured alveolar bone marrow stem cells. It was possible to monitor and capture the live cell morphology cultured in the perfusion bioreactor. The characteristics of the bioreactor developed in this study was fast to culture stem cells with mechanical stimulation and to monitor live cell imaging while promoting healthy cellular activity outside of an incubator environment. Through experimental results, the developed perfusion bioreactor could increase cell growth with proper flow based on mechanical stimuli.
Ki-Woong Sung,Soung Min Ki,mHoon Myoung,Myung-Jin Kim,Jong-Ho Lee 대한구강악안면외과학회 2017 대한구강악안면외과학회지 Vol.43 No.3
Objectives: The purpose of this study was to evaluate and compare the treatment outcomes of partial glossectomy with or without elective neck dissection in patients with tongue squamous cell carcinoma (SCCa). Materials and Methods: A total of 98 patients who were diagnosed with tongue SCCa and underwent partial glossectomy between 2005 and 2014 were evaluated. Only 14 patients received elective neck dissection, and 84 patients received only partial glossectomy. Results: There were 56 men and 42 women with a mean age of 57 years and mean follow-up period of 33.7 months. There were 70 patients graded as T1 and 28 as T2. The total occult metastasis rate was 17.3%. The 5-year overall survival rate was 83.3% with elective neck dissection and 92.4% with observation. The 5-year disease-free survival rate was in 70.7% in the elective neck dissection group and 65.3% in the observation group. Conclusion: We retrospectively reviewed the records of 98 patients with tongue SCCa. These patients were divided into two groups, those who underwent elective neck dissection and those who did not. There was no statistically significant difference between the groups undergoing partial glossectomy with or without elective neck dissection.
증예(症例) : 골화성 근염에 동반된 심부정맥 혈전증 1례
나성일 ( Soung Il Na ),김승수 ( Seung Su Kim ),이동민 ( Dong Min Lee ),윤일용 ( Il Yong Yun ),문우성 ( Woo Sung Moon ),채재건 ( Jei Keon Chae ),김원호 ( Won Ho Kim ),고재기 ( Jae Ki Ko ) 전북대학교 의과학연구소 2002 全北醫大論文集 Vol.26 No.1
Myositis Ossificans is a benign ossifying soft-tissue lesion typically occurring within skeletal muscle. Patients are usually adolescents and young adults. Intraabdominal myositis ossificans is a very uncommon disorder. We experienced a case of myositis ossificans on the lateral wall of the left pelvis, which compressed left external iliac vein cause a deep vein thrombosis(DVT). A 68-year-old woman was admitted with a two-week history of severe lower abdominal pain and swelling of the left lower extrimety. The diagnosis was established with the Doppler ultrasound and pathologic examination. Several studies suggested that catheter-directed thrombolysis and stent placement are potentially attractive forms of therapy because they provide the opportunity for prompt restoration of venous patency and preservation of venous valve function. So we treated the deep vein thrombosis with catheter-directed thrombolysis and percutaneous transcatheter stent placement. We report a case of myositis ossificans presenting with DVT, who had a catheter-directed thrombolysis and percutaneous transcatheter stent placement.
김기준(Ki-Joon Kim),오성영(Soung-Young Oh),한민(Min Han),양형승(Hyeong-Seung Yang),이병우(Byung-Woo Lee) 대한전자공학회 2016 대한전자공학회 학술대회 Vol.2016 No.6
In this paper, to deveop the Live Line Detector by magnetic field measurement of 3 Axis, it used magnetic sensor as non-contacting type. Also, it detected to sensor signal using Lock-in Amp. with Phase Sensitive Detector and Line pass filter. As their development, it will use to detect the live power line in the underground high voltage distribution line.