제왕절개 자궁적출수술의 임상적 고찰

정갑인,남계현,이해혁,이순곤,이권해,김동희 순천향의학연구소 1997 Journal of Soonchunhyang Medical Science Vol.3 No.2

Objective: This study was evaluated twenty-six cases of emergency Cesarean hysterectomy to analyse incidence, age distribution, parity, indications, complications, amount of blood transfusion and fetal morbidity. Methods and Materials : This study was carried out on twenty-six cases who underwent emergency Cesarean hysterectomy at department of obstetrics and gynecology, Soonchunhyang University Hospital from January 1987 to November 1997. Results: 1. The incidence of Cesarean hysterectomy was perfomed in 26 cases among total 19,277 deliveries(0.1%). 2. The indications of Cesarean hysterectomy were uterine atony, placenta previa, adhesive placenta and bleeding tendency. 3. There was matenal death in one case and main cause of death was massive bleeding due to disseminated intrabascular coagulopathy. 4. The complications of Cesarean hysterectomy were disseminated intravascular coagulopathy, bladder injury, postoperative infection, wound disruption and postoperative hemoperitoneum. 5. Two cases of fetal and neonatal mortality were intrauterine fetal death and neonatal death. Conclusion : The incidence of Cesarean hysterectomy was increased by increasing parity and maternal age.

다단계 생산로트크기 결정문제의 분석과 단순화 방법

김갑환,박순오 한국경영과학회 1999 韓國經營科學會誌 Vol.24 No.4

When we try to design a production planning system for a manufacturing company, it is a time consuming task to analyze various planning activities and identify inter-relationship among a lot of decisions made for the production planning. Most of the research efforts have been concentrated to well-organized independent decision-making problems that may usually be identified only after analyzing the characteristics of the decision-making process as a whole in this paper, a methodology is suggested to characterize the whole process of the production planning for a manufacturing company and reduce the complexity of decision-making problem. The methodology is based on an experience of developing a production planning software for an automobile component manufacturer in Korea. First, it is explained how to identify and represent the dependency among various decision-making variables. And a methodology is proposed to analyze the identified dependency among decision variable and identify decision-making process. Lastly, a practical example is provided to illustrate the analysis procedure in this paper.

원기둥의 종횡비가 순수물속에 잠겨있는 등온 수직원기둥에 의해 야기되는 자연대류 열전달에 미치는 영향

유갑종,엄용균,박성순 경북대학교 산업기술연구소 1990 産業技術硏究誌 Vol.18 No.-

A numerical analysis is performed about the effect of aspect ratio on heat transfer adjacent to a vertical-isothermal cylinder of 0℃ in pure water. The numerical results for the effect of aspect ratio are presented for ambient water temperature from 1.0℃ to 15.0℃. They include velocity profiles, temperature profiles and mean Nusselt number for the entire flow field. The mean Nusselt numbers of vertical-isothermal cyinder are compared with that of vertical-isothermal plate in increasing aspect ratio of cylinder. Furthermore, the mean Nusselt numbers of unsteady region in the range of 0.084<R<0.328 are obtained by curve-fitting. The results are summarized as follows : 1. When the range of amient water temperature is 1.0℃≤T_∞≤4.4℃ and 6.0℃≤T_∞≤15.0℃, the mean Nusselt numbers of vertical-isothermal cylinder decrease with the increase in aspect ratio. So the mean Nusselt number of vertical-isothermal cylinder approaches to that of vertical-isothermal plate. 2. When the range of ambient water temperature is 2.0℃≤T_∞≤10.0℃, the value of constant B in Equation (17) is obtained and tabulated in Table 2. 3. The correlations of mean Nusselt number, Rayleigh number and aspect ratio in the unsteady region(0.084<R<0.328) are obtained. And the values of function C are tabulated in Table 4.

인삼첨가방법을 달리한 전통 인삼 약주 제조 연구

국순자,이성갑 한경대학교 2003 論文集 Vol.35 No.-

1. 발효기간동안의 알코올을 함량은 담금 3~5일 사이에 가장 많은 알코올발효가 일어났으며, 담금 후 누룩중의 amylase 작용으로 전분질이 당화되면서 효모에 의한 알코올 발효로 일정기간까지 약주 술덧중의 에탄올 함량은 상승되었다. 2. 담금직후 술덧의 pH가 급격히 감소하였으며 2일 후부터 pH가 점차 증가하였다. 산도는 담금 1일에는 감소하였으나 담금 2일부터 증가하여 발효말기인 6일까지 완만한 추세를 보였다. 3. 환원당은 담금 2일에 가장 높았으며 3일에 급격히 감소하여 발효후기 까지는 서서히 감소하였고 대조구인 순곡주에 비해 인삼을 첨가한 처리구에서 유기산 함량의 큰 변화는 나타나지 않았으며 인삼을 첨가한 처리구에서는 alanine과 proline의 함량이 높게 나타났고 특히 lysine, arginine등의 함량이 생·찐수삼주는 13.93, 43.09 ppm, 순곡주는 11.03, 36.62 ppm으로 순곡주에 비해 높게 나타났다 4. Isoamyl alcohol은 순곡주 351에 비해 생·찐수삼주는 402 ppm이 검출되었으며 에탄올과 유사한 향인 isobutyi alcohol도 순곡주 148에 비해 생·찐수삼주가 209 ppm이 검출되어 이 모든 향기성분이 합하여 발산되므로 생·찐수삼주가 흙냄새를 둔화시켜 주는 것으로 나타났으며 주요 유리당 함량은 glucose>maltose>sucrose>fructose 순이었고 인삼첨가 처리구에서 대조구에 비해 유리당 함량이 높게 나타났다. 5. Ginsenosides는 생수삼주가 13.51 생·찐수삼주는 11.58로 비교구인 홍삼 침출주 9.69보다 높게 검출 되었고 인삼의 첨가로 인해 맛, 향, 종합적 기호도는 전체적로 상승하였다. 6. 이상의 결과로 볼 때 전통 약주의 제조시 인삼의 첨가는 약주의 전체적인 품질을 크게 향상시켰으며 특히 인삼을 생것과 찐 것을 적절히 배합하여 처리한 생·찐수삼주는 isoamyl alcohol, isobutyl alcohol, ethylacetate alcohol등이 인삼을 생으로 마쇄하여 넣은 처리구에 비해 다량 검출되어 이 모든 향기성분이 발산되면서 흙냄새가 둔화되는 것으로 판단된다. 아미노산 발효과정 중 술덧의 이화학적 특성변화는 보이지 않았다. Alcohol was produced the most high content for the first 3~5 days fermentation during all the fermentation period. Lysine and arginine contents were higher in fresh+steamed ginseng wine with values of 13.93 and 43.09 ppm compared to 11.03 and 36.62 ppm for rice wine. Ginsenoside were higher in fresh ginseng wine by 9.69 compared to fresh+steamed ginseng wine with the values of 13.51 for fresh ginseng wine and 11.58 for fresh+steamed ginseng wine. As a results, adding ginseng to the liquor at the time of producing traditional ginseng wine increases the overall quality. Particularly, using sufficient mixture of fresh and steamed ginseng is estimated to weaken the smell of soil as it emits more scent related elements such as isoamyl alcohol, isobutyl alcohol, and ethyl acetate alcohol etc. compared to the trial wine with grinded raw ginseng.

1차원 random media에서 Random walk에 관한 연구

黃甲淳,金慶植 釜山水産大學校 1987 釜山水産大學 硏究報告 Vol.27 No.1

The random walk can be described by the master equation in one-dimensional random media. We study both numerically and analytically the long time asymptotic behavior of the first moment, for the model systems of discrete-time and continuous-time random walks characterized by the transition probability density in the case of nearest neighbor transition. The results of our Monte Carlo method are also showed.

오존수 처리가 콩나물의 부패 및 생육에 미치는 영향

김순동,김일두,김미경,이상갑,민경섭 대구효성가톨릭대학교 식품과학연구소 1997 식품과학지 Vol.9 No.-

오존수 처리가 콩나물의 부패 및 생육에 미치는 효과를 조사하기 위하여 실험 제작한 오존발생장치를 이용하여 콩나물 재배시 수침시의 콩의 세척과 재배중에 오존수로 주수한 결과를 요약하면 다음과 같다. 본 연구에서 개발된 콩의 세척장치와 그 부품을 이용하여 대두량에 대하여 0.5~2.0ppm으로 3시간 처리한 콩으로서 콩나물을 재배하면, 콩의 표면에 오염된 잔류농약이 80~100%까지 분해되었고 콩 g당 10^7정도 오염되어 있는 미생물이 10^3이하로 크게 감소되어 재배중에 부패율은 무처리 경우 10%에서 2%로 현저히 감소되었다. 또, 오존수 주수장치를 이용하여 콩나물재배시에 오존수를 0.5~2.0ppm으로 주수한 결과 부패율을 0%로 낮출 수 있었다. 뿐만 아니라 오존수로 재배한 콩나물은 수율이 증대되었을 뿐만 아니라 비린내가 현저하게 줄었고, 색상과 광택이 양호하였으며, 잔뿌리가 적었다. This study was conducted to investigated the effect of ozone treatment on putrefaction and growth of soybean sprouts ozone was produced using a Hi-Tech ozonator and measured by ozone monitor(Switzerland, Model 3600 analyzer). The soybeans were washed and grown by ozone treatment. The soybeans were exposed to aqueous solutions of ozone at 0.5~2.0ppm for 3 hours. In this ozone treatment, the great decrease in the number of total microbes of soybeans were showed to about 99%. The pesticide residues remained soybean surface were also estimated to 80~100%. The putrefaction of control soybeans during germination was greatly decreased from 10% to 2%. And, that of soybean sprouts was decreased to 0%. The increase of yield, decreases of fish flavor and number of lateral root, and improvement of colour and glaze for soybean sprouts were showed.

양수천자를 받은 임신 및 출산아의 추종관찰

朱甲順,韓鍾卨,李在玄 慶熙大學校 1979 論文集 Vol.9 No.-

The follow-up studies on the outcome of pregnancy and infant having amniocentesis during midpregnancy were analized. Only 483 pregnant women gave the informations for the follow-up study among 1453 patients having amniocentesis during midpregnancy from Jan. 1976 to Dec. 1978 at the department of Obstetrics and Gynecology, Kyung Hee University Hospital. The results were as follows: 1. The 483 pregnant women having amniocentesis gave fullterm delivery in 457 (94.62%), premature delivery in 8 (1.86%), immature delivery in 2 (0.41%) missed abortion in 1 (0.21%), induced abortion in 3 (0.41%) and on pregnancy in 10 (2.07%). 2. Of 473 births, 4 still births, 9 neonatal deaths and 4 infant deaths were encountered. 3. Artificial inductions of the pregnancy were carried out in 3 cases such as a 47 XYY syndrome of the fetus, an anencephalus and a patients who had vaginal leakage of amniotic fluid after amniocentesis. 4. A total of 29 patients complained as follows: Abdominal pain in 15, amniotic leakage in 5, vaginal spotting in 4, amniotic fluid leakage with abdominal pain in 4 and vaginal spotting combined with vaginal leakage in 1. 5. The risks involved in amniocentesis for prenatal diagnosis are in our experience small, so that even the use of relative indication for sampling is justified. However, even if there are no increased statistical risk, there should be carried out by experienced obstetricians. 6. Of 278 term deliveries, 63 (22.66%) cases had permanent contraceptions such as tubal ligations or vasectomies and 100 (35.9%) cases are on temporary contraceptives after delivery.

수리학적 체류시간에 따른 폐활성슬러지의 혐기성 소화 특성

김성순,김갑진,탁성제,김운공 중앙대학교 기술과학연구소 1997 기술과학연구소 논문집 Vol.27 No.-

본 연구는 혐기성 소화 특성을 알아보기 위하여 2차 슬러지를 대상으로 수리학적 체류시간 (Hydraulic Retention Time, HRT)에 따른 유기물 제거효과, 가스발생량 및 탈수특성등을 위한 증온 혐기성 소화실험을 수행하였다. 유기물 제거효율은 HRT에 비례하여 계속 증가하는 경향을 나타내었다. 가스 및 메탄가스 발생량은 HRT가 15이로 증가할 때 까지는 계속 증가하다가 20일에서 오히려 감소하는 경향을 나타내었는데, 이는 유기물의 제거율이 다소 둔화되면서 가스로 전환되지 않고 소화조내에 그대로 축적되었기 때문이라고 판단된다. 한편 슬러지 탈수성은 HRT 증가에 따라 양호해졌다. 상기의 결과로 2차 슬러지의 혐기성 소화시 HRT는 15일에서 유입 VS부하율이 1.09kg VS/㎥/d일 때 가장 좋은 소화 효율을 나타냄을 알 수 있었다. The objectives of this study are to investigate the effect of organic removal and the dewaterability of sludge with Hydraulic Retention Time(HRT) using secondary sludge and estimate anaerobic digestion kinetic coefficient of microorganism. As the results of tests, the efficiency of organic removal increased gradually as the HRT was increased. And gas and methane gas production was increased until HRT got to 15 days. However, at HRT 20days it was significantly lower than HRT 15days. It means that a portion of removal organic matters were accumulated in digester without gasification. In the results of value of specific resistance, dewaterability of sludge was increased proportionally as HRT increased. From the above results, on mesophilic anaerobic digestion of waste acivated sludge, the optimum digestion efficiency was found at HRT 15days with VS loading rate of 1.09 kgVS/㎥/d.

인삼 saponin이 ATPase 活性에 미치는 影響에 관한 硏究

李甲湘,權奉圭,朴映淳 圓光大學校 1983 論文集 Vol.17 No.2

人蔘 Saponin이 토끼의 骨(??)筋小胞體에 結合된 ATPase 活成에 미치는 影響을 測定하였다. ATPase의 活成은 ginseng saponin의 濃渡가 (0.0078% ~ 0.25%) 증가함에 따라 阻害현상을 보여주었고 0.03%에서 50% 阻害를 일으켰다. 이 50% 阻害度는 Dixon plot에서도 약 0.03%로 나타났으며 plot의 pattern으로 보아 ginseng saponin은 allosteric inhibition을 하는 것으로 판단되었다. 이 阻害機作을 알기 위하여 朴(1981)등이 硏究한 水銀이온이 筋小胞體 ATPase의 活成에 可逆的 非競爭的 阻害劑인 結果를 指示價로 하여 Dixon plot, Lineweaver-Burk plot를 作成한 결과 Saponin은 膜性系 結合 APTase에 대하여서는 非競爭的 阻害濟로 판명되었다. saponin은 膜의 表面張力을 저하시켜 주는 연구(朱,1973)로 미루어 볼때 膜性系酸素에 對한 saponin의 阻害는 또다른 物理的 요인도 있는 것 같다. Saponin의 50% 阻害價 0.03%는 水銀에 의한 活成化 에너지의 阻害를 보호해주지 않는 것으로 보아 saponin이 水銀과의 相互作用보다는 ATPase와의 作用에 대한 것 등이 論議되었다.

L1210 세포증식에 대한 Glycyrrhizin의 억제작용 기전

殷載淳,徐龍勳,權鎭,柳東和,吳贊鎬,蘇俊魯,全焄,黃甲洙 우석대학교 의약품개발연구소 1996 藥學硏究誌 Vol.1 No.-

The purpose of this research was to investigate the mechanism of inhibitory action of Glycyrrhizin(GZ) on the proliferation of mouse leukemia cell-line, L1210 cells. The cytotoxic activity was tested using a colorimetric tertrazolium assay(MTT assay), the apoptosis was tested using flow cytometry. Nitric oxide(NO) production form mouse peritoneal macrophage was tested using a Griess method and the phagocytosis of human polymorphonuclear cells was tested using a lucigenin chemiluminescence. GZ ingibited the proliferation of L1210, BALB/c 3T3 cells and mouse thymocytes at 50 ug/ml/ GZ did not affect nitric oxide production from mouse peritoneal macrophages in vitro, but ingibited nitric oxide production from lipopolysaccharide and y-interferon treated macrophages. Macrophages of GZ-administered mice accelerated NO production. The proliferation of L1210 cells apoptosis of L1210 cells were induced by co-culture with macrophage of GZ-administered mice. The apoptosis of L1210 cells were induced by co-culture with macrophage of GZ-administered mice. GZ increased the phagocytosis of human polymorphonuclear cells. These results suggest that GZ inhibit the proliferation of L1210 cells not only as a direct cytotoxic agent o tumor cells, but also by the enhancement of NO production and phagocytic activity.