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      • KCI등재

        도화탕(桃花湯)이 백서(白鼠)의 소화성(消化性) 궤양(潰瘍) 및 장관수송능(腸管輸送能)에 미치는 영향(影響)

        김수정,김진규,백정한,강석봉,이익행,Kim, Soo-Jung,Kim, Jin-Kyu,Back, Jung-Han,Kang, Seok-Bong,Lee, Ik-Haeing 대한한방내과학회 2001 大韓韓方內科學會誌 Vol.22 No.2

        Objectives : In order to study the clinical efficiency of Dohwatang, based on Oriental Medical References, using experimental animals, we studied ulcers, gastric juice secretion, free acidity, total acidity, and the action of transport rates in the intestine. Methods : We used rats administered with the above herbs. Results : Dohwa-tang showed remarkable inhibitory effects on peptic ulcers, gastric juice secretion, free acidity, and total acidity in pyloricligated rat. It also showed remarkable inhibitory effects on the transportability in the large intestine of rats. But Dohwa-tang didn't show any remarkable difference on stressed rats. Conclusions : Dohwatang works better for chronic pyloristenosis-peptic ulcer and for diarrhea than acute stress ulcer.

      • KCI등재

        $(1-x)CaWO_4-xYNbO_4$계 세라믹스의 마이크로파 유전특성

        김수정,김응수,Kim, Su-Jung,Kim, Eung-Soo 한국결정성장학회 2007 한국결정성장학회지 Vol.17 No.5

        [ $(1-x)CaWO_4-xYNbO_4$ ]계에 대하여 $YNbO_4(0.05{\leq}x{\leq}0.4)$의 치환량 변화에 따른 마이크로파 유전특성을 고찰하였다. x=0.10 조성까지 정방정(tetragonal) scheelite 구조의 $CaWO_4$ 단일상이 확인되었고, 그 이상 첨가 시 fergusonite 구조의 2차상이 증가하였다. $YNbO_4$ 첨가량이 증가할수록 겉보기 밀도는 감소하였는데, 이는 $CaWO_4(6.117g/cm^3)$보다 $YNbO_4(5.581g/cm^3)$가 더 낮은 이론밀도 값을 갖기 때문이다. $YNbO_4$의 첨가량이 증가함에 따라 유전상수(K)와 품질계수(Qf)는 2차상의 증가와 밀도의 감소로 인해 감소하는 경향을 보였고, $YNbO_4$ 치환량에 따른 소결시편의 공진주파수 온도계수(TCF)의 변화는 존재상의 유전체 혼합 법칙(dielectric mixing rule)에 의존하였다. Microwave dielectric properties of $(1-x)CaWO_4-xYNbO_4$ ceramics have been investigated as a function of $YNbO_4$ content($0.05{\leq}x{\leq}0.4$). A single phase with tetragonal scheelite structure was obtained up to x=0.10 and then the secondary phase with fergusonite structure was increased. With the increase of $YNbO_4$ content, apparent densities of the specimens were decreased. This results were due to the lower theoretical density of $YNbO_4(5.581g/cm^3)$ than that of $CaWO_4(6.117g/cm^3)$. Dielectric constant(K) and quality factor(Qf) were decreased with $YNbO_4$ content which could be attribute to the decrease of density and the increase of secondary phase. Temperature coefficient of resonant frequency (TCF) of the specimens with the $YNbO_4$ content was depended on dielectric mixing rule.

      • KCI등재후보

        감귤 내 생리활성성분이 간암세포의 생존에 미치는 영향

        김수정,박덕배,Kim, Soo Jung,Park, Deok Bae 제주대학교 의과학연구소 2018 The Journal of Medicine and Life Science Vol.15 No.1

        Previous studies have suggested that Citrus fruits might suppress the proliferation of various cancer cells. However, little is known about any specific ingredients in the extract of Citrus fruits to exert its anti-proliferative activity in cancer cells. The present study aimed to identify the active ingredients in Citrus fruits to suppress the proliferation of rat hepatocellular carcinoma cells. Among tested compounds, two polymethoxylated flavones (nobiletin and tangeritin) showed significant anti-proliferative activity whereas other compounds (synephrine, rutin, hesperidin) did not. Interestingly, nobiletin as well as tangeritin also decreased the protein amount of gluconeogenic enzymes, PEPCK and G6Pase. The possible involvement of gluconeogenic activity in the proliferation of hepatocellulacarcinoma cells are further to be investigated.

      • KCI등재

        홍경천(Rhodiola sachalinensis A. Bor)의 캘러스 배양에서 Salidroside생산

        김수정,황백,황성진,안준철,Kim, Soo-Jung,Hwang, Baik,Hwang, Sung-Jin,Ahn, Jun-Cheul 한국식물생명공학회 2004 식물생명공학회지 Vol.31 No.1

        본 실험은 기내 배양된 홍경천으로부터 캘러스를 유도하고 가장 잘 자라는 생장조건을 찾기 위해 수행되었다. 실험 결과를 종합해 보면 캘러스의 증식을 위한 배양조건은 최적배지를 조사한 결과,2B$_{5}$배지에서 생장율이 가장 좋았으며, 탄소원으로는 sucrose를 3%로 첨가했을 때 생장율이 가장 높았다. 질소원으로써는 49.6mM KNO$_3$와 2.0mM (NH$_4$)$_2$SO$_4$를 첨가했을 때 생장율이 가장 좋았으며, 인산의 농도는 2.16mM에서 높은 생장율을 보였다. 암배양과 광배양을 비교했을 때 암배양의 경우가 생장율이 높았으며,pH6에서 세포의 생장율이 가장 좋은 조건임을 확인되었다. 기내에서 배양된 캘러스와 자연산 뿌리는 TLC로 분석하여 salidroside를 확인하였으며, HPLC로 salidroside를 정량한 결과, 자연상태 홍경천의 뿌리는 건중량 당 0.17%으로 나타났으며 5% sucrose처리구에서 0.41%의 생산성을 보여, 자연산 홍경천의 뿌리에 비하여 캘러스에서 salidroside의 함량이 높은 것으로 나타났다. Callus of Rhodiola sachalinensis A. Bor were induced from leaf explant on l/2MS solid supplemented with combination of auxin (2.4-D, NAA: 0.1∼2mg/L) and cytokinin (BA: 0.1∼0.2mg/L). The effects of various medium, culture conditions and phytohormones on the growth of callus were investigated. MS, WPM, B$_{5}$ medium and diluted or concentrated media (1/2X, 2X, 3X) were used to investigate the growth of callus on each media. Among these, the highest growth was observed when cultured in in 2B$_{5}$ medium containing 0.5mg/L NAA and 1mg/L BA, 3% sucrose and 49.6 mM KNO$_3$ as nitrogen source, and 2.16mM NaH$_2$PO$_4$ as phoshate source at $25^{\circ}C$ in the dark. The calli cultured with 5% sucrose produced high salidroside content (0.41% on the basis of dry wt) than normal root (0.17%).

      • SCOPUSKCI등재

        건성피부 및 소양증에 대한 잘스밍R 크림의 임상효과에 대한 연구

        김수정,이인욱,최응호,이원수,안성구 ( Soo Jung Kim,In Wook Lee,Eung Ho Choi,Won Soo Lee,Sung Ku Ahn ) 대한피부과학회 1997 대한피부과학회지 Vol.35 No.3

        Background: Xerosis is a relatively common disorder, especially in the elderly. The condition is characterized by fine scaling and is associated with generalized pruritus. Objective : The purpose of this study was to evaluate the clinical efficacy, safety and tolerability of Zalsming cream in patients with xerosis and pruritus. Methods : Thirty patients were treated with Zalsming cream. Clinical efficacy, as measured by the score of subjective symptom and objective signs, transepidermal water loss(TEWL) and electron microscopic finding, were asessed at 2, 4, and 6 weeks after topical application of the cream. Results . The scores of clinical signs and TEWL showed statistically significant improvements. No one developed any local or systemic side effects. Conclusion : Topical application of Zalsming cream was found to be effective and safe for patients suffering from xerosis and pruritus. (Kor J Dermatol 1997;35(3): 418-423)

      • 영어의 비강세 약모음 schwa /e/의 음성실현

        김수정,Kim, Soo-Jung 한국음성학회 2005 음성과학 Vol.12 No.4

        The present study examines the phonetic realizations of the unstressed weak vowel /e/ in English words produced by native and Korean ESL speakers. Traditionally, the stressed elements in utterance are considered to be prominent. In this sense, the unstressed weak vowel /e/ is predicted to be shorter in length, lower in pitch and intensity than the stressed vowels. The experiment shows that native English speakers correlate the unstressed weak vowel /e/ with both shorter duration and lower pitch; Korean ESL speakers correlate it with lower pitch only. We cannot find any significant statistical difference in intensity between /e/ and the stressed vowels in both cases. This study suggests it is important to acquire and produce the correct prosodic correlates of the unstressed weak vowel /e/ for Korean ESL speakers to command more natural English intonation, since /e/ is the most common vowel in English speech and consists of the English foot rhythm along with stressed vowels.

      • KCI등재

        영어교육 자료로서 광고의 활용 : 모의수업 연구

        김수정(Kim Soo-Jung),남정미(Nam Jung-Mi) 새한영어영문학회 2009 새한영어영문학 Vol.51 No.4

        The purpose of the present study is to examine the effectiveness of a preliminary study of utilizing advertising English for instructional materials. The study also aims to explore students’ opinions about English advertisements as authentic materials for EFL instruction. For the purpose, an experiment along with a questionnaire survey was conducted. In terms of control group and experimental group, the students’ pre-test and post-test scores were also compared. The findings show that there are statistically significant differences between pre-test and post-test scores. Moreover, advertising English is useful for enhancing students’ interests in EFL classes and gaining understanding of American cultures. Based on the study results, positive and negative aspects of employing advertisements for EFL instruction and the instructor’s important role in selecting and utilizing appropriate materials are discussed. Finally, pedagogical implications are provided on how to employ English advertisements for effective Enlish instruction.

      • KCI등재

        An Analysis of English Sound Recognition in Secondary Schools based on Korean High School Students' Vowel Pronunciation

        Kim, Soo-Jung(김수정),Koo, Hee-San(구희산) 중앙대학교 한국교육문제연구소 2007 한국교육문제연구 Vol.25 No.1

        본 논문은 영어발음 중에서도 모음 발음을 중심으로 하여 한국 고등학교 학생들의 청취 능력과 발음 능력을 알아보고 문제점을 발견하는데 그 목적이 있다. 본 논문에서 실시한 실험은 듣기 문항, 철자보고 발음기호 구별, 그리고 발음기호 쓰기로 나눌 수 있다.듣기 문항 실험 결과는 반이 조금 넘는 학생들(53%)이 모음을 올바르게 식별해 내는 것으로 나타났다. 철자보고 발음기호 구별 실험에서는 학생들이 잘 식별하는 모음이 /a, ʌ, e, æ, ɔ, ou/이고, 발음을 잘 식별하지 못하는 모음이 /u, ʋ, i, ɪ/라는 것을 알 수 있었다. 발음기호 쓰기 실험에서는 학생들이 잘 쓰는 모음이 /ʋ/와 /ɪ/였고 잘 쓰지 못하는 모음이 /ʌ, ɔ, ou/였다. 따라서 교사는 이완 모음을 더 지도할 필요가 있고 학습자들은 발음기호 교육과 받아쓰기 연습이 필요하다. 그리하여 교사는 영어발음 교육에 대한 지속적인 탐구 및 충분한 지식을 가지고 학생들을 지도해야만 한다. 또한 수업시간에 간단히 받아쓰기를 실시하는 등의 학습을 통하여 듣기의 이해 능력 향상을 도모해야 할 것이다. The purpose of this analysis is to identify the problems of  discriminating and writing down English vowels in a secondary English education.The first-year high school students were selected at random and tested on their listening, discriminating pronunciation and writing down the phonetic transcriptions. The results showed that more than half the students have good listening abilities. In the discriminating pronunciation test, most students correctly discriminated the following vowels:/ɑ, ʌ, e, æ, ɔ, ou/. However, they incorrectly discriminated the following vowels:/u, ʋ, i, ɪ/. In writing down the pronunciation test, most of them were good at writing down the vowels of /ʋ/ and /ɪ/, but they were not good at writing down the vowels of  /ʌ, ɔ, ou/.The thesis makes three proposals for more efficient teaching of English pronunciations. First, teachers need to teach students more of the lax vowels than the tense vowels. Second, the education of phonetic transcription is needed. Third, students need to practice on the dictation.

      • KCI등재

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