인천 인현동 호프집 화재 피해자 분석

최정태,안무업,안희철,최영미,정재봉,서정열,유기철,이삼우,박석현,조준휘,김성환,김아진,송근정 대한응급의학회 2001 대한응급의학회지 Vol.12 No.4

Purpose : This study was conducted to develop field triage, transportation, distribution, and prehospital care at a fire disaster by analyzing the victims of the fore that broke out at a bar in Incheon. Method : We analyzed the cases of the victims of a fire in Incheon in Oct. 1999. We determined the primary care hospital, the arrival time, the burn size, the outcome, and the injury type from the medical records, the concerned organ records, and interviews with concerned persons. Result : The total number of victims was 137: 56 prehospital deaths, 1 hospital death, and 80 survivals. The Pearson correlation coefficient between the burn size and the severity was -0.175. There were 121(89.6%) cases of inhalation injury, 59 (43.7%) cases of flame burns, 66 (48.9%) cases of hypoxic brain damage, and 16 (11.9%) cases involving other types of injury. Conclusion : The causes of death of the fire victims were inhalation injury and hypoxic brain damage due to CO poisoning and other toxic inhalants. We propose the use of a simple triage and rapid treatment(START) system and a reassessment the delayed category in fire disasters.

유기농 및 관행 재배 벼 미강의 항산화 활성 분석

최장열,이성진 全南大學校 農業科學技術硏究所 2011 農業科學技術硏究 Vol.46 No.-

To compare antioxidant activities between organic and conventional cultivation of rice bran, three kinds of rice species-Hopum, Hopyeong, and Yungwang-were selected and cultivated in Chonnam province. After cultivation, rice bran was extracted with 70% methanol and analyzed protective activity against oxidative stress induced-cell death and antioxidant activities such as inhibition of intracellular reactive oxygen species (ROS) generation and lipid peroxidation in hepatocellular carcinoma HepG2 cells. When HepG2 cells were treated with three kinds of rice bran extracts for 24 h and followed by the treatment of 1 mM H2O2, organic Hopum and Hopyeong rice bran showed the higher protective activities against oxidative stress induced-cell death than their conventional cultivated rice brans. Yungkwang rice bran did not showed the difference between organic cultivation and conventional cultivation. Organic Hopum, Hopyeong, and Yungkwang rice bran extracts reduced the intracellular ROS generation induced by 1 mM H2O2 more efficiently than their conventional-cultivated rice bran extracts. However, tested rice bran extracts did not show the strong protective effects on lipid peroxidation. From the study, organic Hopum and Hopyeong rice bran extracts showed the higher antioxidant activities than their conventional cultivations and these results indicate that even though phytonutrient contents of rice bran were not measured, significant difference between two cultivation practices were evident.

정신분열병 환자들의 自己灣入에 관한 예비 연구

박성봉,김영미,전성일,이기철,김영훈,정영조,이영렬,이정호,최영민 大韓神經精神醫學會 1997 신경정신의학 Vol.36 No.6

목 적 : 정 신분열병 환자의 자기만입 정도에 영향을 미치는 인구학적 변인들 및 질병연관 변인들을 규명해 보고자 하였다. 또한. 환자들의 자기만입과 병식 사이의 연관성. 자기만입과 자존심 사이의 연관성을 알아보고자 하였다. 방 법 : 정신과 의사가 병록지와 면담을 통하여 대상 정신분열병 환자들의 인구학적 변인들 및 질병연관 변인들에 관한 자료를 얻고 환자들의 병식 정도를 평가한 후, 환자들로 하여금 자기보고형의 자기만입 척도와 자존심 척도를 시행하게 하였다. 총 111명의 환자가 연구대상으로 선택되었다. 결과: . 1) 여자가 남자보다 유의하게 높은 자기만입 척도 점수를 나타내었다 2) 질병연관 변인들 중 하위집단 사이에 자기만입 척도 점수의 유의한 차이를 보이는 변은 없었다. 3) 자기만입 척도 점수와 병식 점수 사이에 유의한 상관관계가 없었다. 4) 자기만입 척도 점수와 자존심 척도 점수 사이에 유의한 역상관 관계를 보였다. 결 론 : 본 예비 연구의 결과로 보아 정신분열 병 환자의 병식이 부족한 상태에서도 자기만입이 진행될 수 있으며. 자기만입이 심할수록 환자의 자존심이 저하되는 것으로 생각된다. 또한 여자 환자들이 남자 환자들보다 자기만입에 더 취약한 것으로 생각된다. 따라서 정신분열 병 환자의 이해와 치료를 위하여 자기만입에 관한 지속적인 연구가 필요할 것으로 생각된다. objective : This study was conducted to identify demographic variables and illness related variables which may affect the severity of self-engulfment in the patients with schizophrenia. We also studied the relationship between self-engulfment and insight, and the relationship between self-engulfment and self-esteem. Methods : Data on demographic variables and illness related variables for the subjects were gathered from hospital records and clinical interviews by the psychiatrists. Degree of insight for the subjects was assessed through clinical interviews by the psychiatrists. Degree of self-engulfment and self-esteem for the subjects was assessed from the self-engulfment scale and the self-esteem scale respectively. A total of 111 patients with schizophrenia were selected for statistical analysis. Results 1) The females exhibited significantly higher scores than the males on the self-engulfment scale. 2) There was no illness related variable, which exhibited a significant difference among subgroups on the self-engulfment scale. 3) There was no significant correlation between the self-engulfment scores and the insight 4) There was a significantly inverse correlation between the self-engulfment scores and the self-esteem scores. Conclusion : The results of this preliminary study suggest that self-engulfment may develop despite lack of insight and that there was inverse relationship between self-engulfment and self-esteem in the patients with schizophrenia. It also suggests that females are more subject to self-engulfment than males. So, authors suggest that it is valuable to do further studies of self-engulfment in the patients with schizophrenia.

DFSS에 의한 FPD용 높이 조절기구 설계

정선환,최성대,조규열 한국공작기계학회 2006 한국공작기계학회 추계학술대회논문집 Vol.2006 No.-

This study was carried out to minimize the lifting force and to design the slim sized frame of a height adjustment mechanism. This unit is designed for the display devices in order to enhance the ergonomics for effective height adjustment as well as to achieve much slimmer frame for the pedestal. A tolerance analysis of 6 sigma was applied to achieve smooth lift at design stage not to change the tolerance specification of gap several times in a roller type of lifting mechanism at mass production stage. The specification of minimum gap and the target of production yield ratio were agreed with a quality team before tooling. A DFSS simulation on drawings had been done with reasonable tolerance and achievable standard deviation(σ) several times until the target spec of gap and yield ratio was met. Once tolerance and deviation(σ) were fixed tooling start was done successfully. A CAE method was applied to achieve a slim design. Design parameters were frozen when those parameters matched the reference strength data of standard model. Through those tolerance analysis and CAE simulation the number of tool modification was reduced and production yield ratio was raised up without arguing quality specification at production stage in the end.

간척지에서 옥수수 나방류 해충 3종의 발생소장

이휘종,최원영,김상열,서종호,황정동,오성환,정진교,김주일,구현나,김길하 忠北大學校 農業科學硏究所 2015 農業科學硏究 Vol.31 No.2

Occurrence of three troublesome lepidopterous pests, Ostrinia furnacalis, Helicoverpa armigera and Pseudaletia separata in corn cultivation of the reclaimed land were recorded using sex pheromone traps from 2012 to 2014. In case of O. furnacalis adult, two generations were observed in a year and its occurrence pattern was very regular. The 1st generation showed the highest occurrence in late May-early June and the 2nd generation was in late July-early August. On the other hand, H. armigera occurred at least three times a year but its occurrence was somewhat irregular. H. armigera adult showed the highest occurrence in mid May, late June, early August, respectively in 2012 but their occurrence patterns of the 2nd and 3rd generations were varied in 2013 and 2014. In case of P. separata, a few number of adult were captured during the survey period, indicating few number of P. separata migrated from China. Based on the control effect of O. furnacalis by Etofenprox and Carbofuranin 2012, June 26 treatment showed the highest control rate with 96.8% for Etofenprox, 85.8% for Carbofuran, respectively. Late treatment at June 19 and June 26 significantly decreased the control rate of O. furnacalis and June 26 treatment showed the lowest control rate of 1.9% for Etofenprox. 18.1% for Carbofuran, respectively.

Performance Analysis of the First Korean Satellite Laser Ranging System

Choi, Man-Soo,Lim, Hyung-Chul,Choi, Eun-Jung,Park, Eunseo,Yu, Sung-Yeol,Bang, Seong-Cheol,Kim, Tae-Keun,Kim, Young-Rok,Kim, Dong-Jin,Seong, Kipyung,Ka, Neung-Hyun,Choi, Cer-Hee,Hwang, Joo-Yeon,Kuchars The Korean Space Science Society 2014 Journal of Astronomy and Space Sciences Vol.31 No.3

The first Korean satellite laser ranging (SLR) system, Daedeok SLR station (DAEK station) was developed by Korea Astronomy and Space Science Institute (KASI) in 2012, whose main objectives are space geodesy researches. In consequence, Korea became the $25^{th}$ country that operates SLR system supplementing the international laser tracking network. The DAEK station is designed to be capable of 2 kHz laser ranging with precision of a few mm both in daytime and nighttime observation of satellites with laser retro-reflector array (LRA) up to the altitude of 25,000 km. In this study, characteristics and specifications of DAEK station are investigated and its data quality is evaluated and compared with International Laser Ranging Service (ILRS) stations in terms of single-shot ranging precision. The analysis results demonstrated that the DAEK station shows good ranging performance to a few mm precision. Currently, the DAEK station is under normal operations at KASI headquarters, however, it will be moved to Sejong city in 2014 to function as a fundamental station for space geodesy researches in combination with other space geodesy systems (GNSS, VLBI, DORIS, etc.).

Comparative Analysis of the Antioxidant Activities of Green Peppers Cultivated under Conventional and Environmental-Friendly Farming conditions

Choi, Jang-Yeol,Choi, Yeo-Jin,Lee, Seong-Gene The Korean Society of Environmental Agriculture 2010 한국환경농학회지 Vol.29 No.1

Environmental-friendly agriculture (EFA) is defined as the cultivation of crops with reduced amounts or without chemical-synthetic pesticides. Recently, the use of chemical pesticides has decreased significantly; therefore, we cultivated peppers following EFA- and conventional methods and compared their antioxidant activities. To accomplish this, the environmental-friendly cultivated peppers (EFPE) and conventionally cultivated peppers (CCPE) were extracted with 70% methanol and the effects of the extracts on the cell viability, intracellular ROS generation, lipid peroxidation and catalase activity of HepG2 cells were evaluated. EFPE showed a stronger protective effect against oxidative stress induced-cell death than that of CCPE. EFPE also reduced intracellular ROS generation (42.7% to 26.4%) following treatment with hydrogen peroxide more effectively than that of CCPE (24.2% to 6.3%). Furthermore, EFPE and CCPE showed protective effects against lipid peroxidation and induced catalase activity, although these effects were not statistically significant. Taken together, these results suggest that EFPE showed stronger antioxidant activities than CCPE, and thus represent evidence that EFA with biocontrol materials may improve the functional properties of crops and/or secondary metabolites with antioxidant activities when compared with conventional agricultural practices.

Violacein and bacterial predation: promising alternatives for priority multidrug resistant human pathogens

Choi, Seong Yeol,Im, Hansol,Mitchell, Robert J Future Medicine 2017 Future microbiology Vol.12 No.10

Violacein: Properties and Production of a Versatile Bacterial Pigment

Choi, Seong Yeol,Yoon, Kyoung-hye,Lee, Jin Il,Mitchell, Robert J. Hindawi Publishing Corporation 2015 BioMed research international Vol.2015 No.-

<P>Violacein-producing bacteria, with their striking purple hues, have undoubtedly piqued the curiosity of scientists since their first discovery. The bisindole violacein is formed by the condensation of two tryptophan molecules through the action of five proteins. The genes required for its production, <I>vioABCDE</I>, and the regulatory mechanisms employed have been studied within a small number of violacein-producing strains. As a compound, violacein is known to have diverse biological activities, including being an anticancer agent and being an antibiotic against <I>Staphylococcus aureus</I> and other Gram-positive pathogens. Identifying the biological roles of this pigmented molecule is of particular interest, and understanding violacein's function and mechanism of action has relevance to those unmasking any of its commercial or therapeutic benefits. Unfortunately, the production of violacein and its related derivatives is not easy and so various groups are also seeking to improve the fermentative yields of violacein through genetic engineering and synthetic biology. This review discusses the recent trends in the research and production of violacein by both natural and genetically modified bacterial strains.</P>

<i>Chromobacterium violaceum</i> delivers violacein, a hydrophobic antibiotic, to other microbes in membrane vesicles

Choi, Seong Yeol,Lim, Sungbin,Cho, Gayoung,Kwon, Jisoo,Mun, Wonsik,Im, Hansol,Mitchell, Robert J. BLACKWELL SCIENCE 2020 ENVIRONMENTAL MICROBIOLOGY Vol.22 No.2

<P><B>Summary</B></P><P>This study describes <I>Chromobacterium violaceum</I>'s use of extracellular membrane vesicles (MVs) to both solubilize and transport violacein to other microorganisms. Violacein is a hydrophobic bisindole with known antibiotic activities against other microorganisms. Characterization of the MVs found they carried more violacein than protein (1.37 ± 0.19‐fold), suggesting they may act as a reservoir for this compound. However, MVs are not produced in response to violacein – a Δ<I>vioA</I> isogenic mutant, which is incapable of making violacein, actually produced significantly more MVs (3.2‐fold) than the wild‐type strain. Although violacein is insoluble in water (Log P<SUB>octanol:water</SUB> = 3.34), 79.5% remained in the aqueous phase when it was present within the <I>C. violaceum</I> MVs, an increase in solubility of 1740‐fold. Moreover, tests with a strain of <I>Staphylococcus aureus</I> showed MV‐associated violacein is bactericidal, with 3.1 mg/l killing 90% of <I>S. aureus</I> in 6 h. Tests with the Δ<I>vioA</I> MVs found no loss in the <I>S. aureus</I> viability, even when its MVs were added at much higher concentrations, demonstrating violacein is the active component within the wild‐type MVs. In conclusion, our study clearly demonstrates <I>C. violaceum</I> produces MVs and uses them as vehicles to solubilize violacein and transport this hydrophobic antibiotic to other microbes.</P>