허혈성 심질환에서 염증지표에 관한 연구

번정득,권영주,박상호,한대희,이상철,강진환,김명구,심규혁,최병조,온영근,현민수,김성구 순천향의학연구소 2001 Journal of Soonchunhyang Medical Science Vol.7 No.2

Background : Atherosclerosis is the chief underlying cause of ischemic heart disease and there is increasing evidence that inflammation is an important determinant of the development of atherosclerosis. We assessed the levels of inflammatory markers in patients with ischemic heart disease and normal group who has normal coronary angiograms. Materials and Methods : Coronary angiography was performed in 142 patients. 107 patients of ischemic heart disease(stable angina pectoris 58, unstable angina pectoris 30, Acute myocardial infarction 19) and 38 normal control subjects. We assessed the level of inflammatory markers, such as CRP, ESR, fibrinogen and leukocyte. Results : CRP, ESR and fibrinogen values of the patients with stable angina pectoris and unstable angina pectoris were higher than that of normal control group, but there were no statistical significance. Leukocyte value of the patients with unstable angina pectoris(9003.3±701.5/mm^(3)) was significantly higher than that of the patients with stable angina pectoris(6685.5±245.8/mm^(3)) and normal control subjects(6394.3±235.1/mm^(3)). CRP, ESR and fibrinogen values of the patients with acute myocardial infarction were also higher than that of normal control subjects. CRP was 3.88±2.05 mg/dL in acute mocardial infarction group, and 0.29±0.15 mg/dL in normal control subject group(p<0.05). Fibrinogen was 541.6±45.1 mg/dL in acute myocardial infarction group, 321.4±25.6 mg/dL in normal control subject group(p<0.05). Leukocyte was 10942.1±737.6/mm^(3) in acute myocardial infarction group, 6394.3±235.1/mm^(3) in normal control subject group(p<0.05). Conclusions : This study demonstrate that CRP, fibrinogen and leukocyte values of acute myocardial infarction group were significantly higher than that of control group and stable, unstable argina pectoris group. Leucokyte values were significantly elevated in unstable angina group, but CRP values were not in unstable angina group.

관상동맥질환 환자에서 스텐트 시술 후 재협착에 관한 연구

강진환,권영주,박상호,한대희,이상철,김명구,변정득,최병조,심규혁,온영근,현민수,김성구 순천향의학연구소 2001 Journal of Soonchunhyang Medical Science Vol.7 No.2

Background and aims : In the coronary artery disease, a rate of restenosis was much decreased by placement of coronary stent than when percutaneous transluminal coronary angioplasty has been applied, but there are still important clinical problems of restenosis. There has been many progressive studies about various factors contributed to this restenosis. So, we studied a relation between restenosis after placement of coronary stent in the coronary artery disease and many clinical factors, characteristics of stenotic lesion and procedural factors, and also assessed the restenosis rate of various coronary stents. Methods : Total 58 lesions(46 cases of patients ; man 30, woman 16) were evaluated, which has been performed a follow-up coronary angiography after 6 months (mean 188 days) since coronary stent had been placed. Various stents were implanted and assessed a relation between restenosis and many factors. Results : Of 58 lesions were target stenotic studies, there were 22 of restenotic lesions(37.9%), and the restenosis rate wes statistically significant difference in the relation with diabetes mellitus(p<0.05), group of acute myocardial infarction(p<0.05) among clinical diagnosis of ischemic heart disease(stable angina, unstable angina and acute myocardial infarction) in clinical factors and with high dilation pressure of stent(p<0.05) in procedural factors. When the rate of restenosis was evaluated among implanted stents, it was lowest in the Multilink^(®) stent and highest in the Nir Royal^(®) stent(60%). Conclusion : In this study of restenosis and various factors after placement of stents in the coronary artety disease, factors such as diabetes mellitus, group of acute myocardial infarction and a dilation pressure of stent were significant related with restenosis and the restenosis rate of Multilink^(®) stent was lowest and the highest restenosis rate was of Nir Royal^(®) stent.

알코올 의존 환자에서 금주시간에 따른 갈망 정도와 Leptin, ACTH, Cortisol 혈중 농도의 변화와 상관 관계

김봉조,변기욱,한규희,손진욱,박철수,곽욱환 대한생물치료정신의학회 2002 생물치료정신의학 Vol.8 No.1

만성 심부전환자의 혈액에서 측정한 Tumor necrosis factor-α 및 Interleukin-6의 임상적 의의

김명구,김성구,박상호,한대희,강진환,변정득,심규혁,최병조,방덕원,온영근,현민수,권영주 순천향의학연구소 2001 Journal of Soonchunhyang Medical Science Vol.7 No.2

Background and objectives: Many conditions are responsible for the pathophysiology and progressive mechanisms of congestive heart failure. More recently, it has also become evidence that another class of biologycally activated molecules generically reffered to as cytokine these are also over expressed in congestive heart failure. Therefore, the purpose of this study was to measure concentrations of tumor necrosis factor-α(TNF-α), interleukin-6(IL-6) in mild to severe symptoms of heart failure and compare their values with those found in normal control and analysed correlation relationship between cytokine level, clinical findings and hemodynamic indicies. Subjects and Methodology: Levels of TNF-α and IL-6 were measured on pulmonary artery during cardiac catheterization in heart failure patients(n=32) and normal subjects(n=8) as well as physical examination and echocardiogram. Cytokines assay were performed on plasma using commercially available ELISA(Enazyme-Linked Immunosorbent Assay) kits. Results: Although the levels of TNF-α and IL-6 tend to increase in congestive heart failure group, the cytokines level was not made significantly statistical difference between congestive heart failure group and controls. When analyzing the correlation between the levels of PCWP(pulmonary capillary wedge pressure) and cytokines(TNF-α, IL-6), respectively, there were statistically significant correlation coefficient 0.32,(p<0.05), 0.39(p<0.01). The cytokine IL-6 and pressure of pulmonary artery were significant correlation.(correlation coefficient 0.36, p<0.02) More significantly, there was correlated with TNF-α and IL-6.(correlation coefficient 0.57, p<0.001) Conclusions: There was tended toward high concentration of TNF-α & IL-6 in congestive heart failure and significant difference for PCWP between TNF-α & IL-6, thus may be correlated with development and progression in congestive heart failure.

AHP를 이용한 KOICA 농업분야 원조사업의 평가

변규환(Byun, Kyu Hwan),송양훈(Song, Yanghoon) 한국농식품정책학회 2016 농업경영정책연구 Vol.43 No.4

The amount of aids by Korea continues to grow, and it is essential to increase the effectiveness of Korea’s aid in line with the goals of international society. Therefore, the goal of this study is to develop a quantitative approach, by which aid effectiveness can be measured and increased, with application to the previous agricultural ODA projects of Korea International Cooperation Agency (KOICA). To this end, this study utilizes the Analytic Hierarchy Process that makes use of evaluation scores of experts from evaluation reports (meta-evaluation) and field visits. Among The five OECD DAC criteria, it is found that Effectiveness is the most important criterion, while in the analysis of priorities in agriculture, Agricultural Water Resources is found to be the most important area. By applying the same method to the subcategories, criteria by which to compare projects and to determine the order of priorities is established. This study also analyzes the attributes of agricultural ODA projects of KOICA by examining the factors that affect project performance, international studies on aid effectiveness, the OECD DAC Peer Reviews, CDI, and QuODA. Project size in budget and period are selected as internal factors. Policy, cultural environment, economic structure, and population distribution of the partner countries are selected as external factors. The key analytic result from using the aforementioned factors is that there is no significant relationship among project performance and internal factors. However, significant relationships among project performance and external factors are found, in line with partner countries’ characteristics. Furthermore, the key analytic results in terms of economic structure and population distribution are that the performance of the agricultural ODA projects of KOICA is positively related to the agricultural GDP of the partner countries, and that they show high-level performance in regions with a high proportion of rural residents. Based on these findings, the important of the agricultural sector in reducing poverty in the ODA projects in agriculture of KOICA is confirmed.

Calibration of Color Indices For Diagnosing Nitrogen Nutrition Status of Rice Canopy

Kyu-Jong Lee,Yong-Feng Yan,Doug-Hwan Choi,Nhuan Duc Nguyen,Byun-Woo Lee 한국작물학회 2008 한국작물학회 학술발표대회 논문집 Vol.2008 No.10

Leaf color can be used as an indicator of the plant healthiness, and thus digital image analysis may provide farmers and researchers with time- and resource-saving methods for diagnosing plant nutrient status. The digital images are dependent on the ambient light, therefore the color indices of digital images should be compensated for the difference of ambient light. The objectives of this study were to develope the calibration methods for color indices under variable irradiance condition. Four color panels were used for RGB (Red, Green, Blue) values and color indices calibration purpose. Reflectance for each panel was measured by spectro-radiometer with a waveband range of 300 - 1100 nm. The reflectance values of four color panels was used as a reference for calibration of RGB values and color indices. Using digital camera color images were taken for rice canopies together with reference panel that was set up at the level of canopy surface. Digital images were obtained form rice fields with variable nitrogen fertilization managements at active tillering to panicle initiation stage. The calibration coefficients for color image indices were calculated by using the linear regression equation between the pixel values of color image for reference panel and their known reflectance values. The determination coefficients (r2) of linear regression between non-calibrated mean B values of plant pixels in color image and shoot nitrogen contents in four rice varieties, Odae, Hwasung, Chucheong, and Ilpum, was 0.30, 0.27, 0.37, and 0.27, respectively, while the respective r2 values were increased to 0.79, 0.85, 0.77, and 0.53.by applying the calibration coefficient. These results imply that color digital image analysis could be a promising method for diagnosing nitrogen nutrition status of rice canopy.

Capillary grooves fabricated by extrusion method for cooling application

Seok-Hwan Moon,Kyu-Ho Lee,In-Kyu You,Hyung-Man Lee,Chang-Wan Byun 한국생산제조학회 2012 한국생산제조시스템학회 학술발표대회 논문집 Vol.2012 No.10

Biological characteristics and mass rearing of Korean Luciola lateralis Motschulsky

Do-Hwan Jang,Bong-Kyu Byun 한국응용곤충학회 2022 한국응용곤충학회 학술대회논문집 Vol.2022 No.10

분포형 TDR 센서의 최적 보정 환경 구축

김규호(Kyu-Ho Kim),지연정(Yeon-jeong Ji),김태민(Tae-Min Kim),변상봉(Sang-Bong Byun),이용환(Yong-Hwan Lee),김영형(Young-Hyung Kim) 한국정보기술학회 2021 Proceedings of KIIT Conference Vol.2021 No.11

열 수송관의 누수, 파열로 인한 지중 온도 및 누수 감지를 위한 방법으로는 TDR 센서를 사용하는 방법이 있다. 다만 TDR 센서의 측정치는 수분 함유량에 따라 유전율이 달라지는 특성이 있고 분포형으로 구성 시, 시간에 따른 불규칙한 노이즈를 포함하고 있다. 본 논문에서는 분포형 TDR 센서를 위한 최적의 보정 알고리즘을 설계하여 최상의 결과를 얻을 수 있는 환경을 구축한다. There is a method using a TDR sensor as a method for detecting ground temperature leakage and due to leakage or rupture of a heat transport pipe. However, the measured value of the TDR sensor has a characteristic that the dielectric constant varies according to the moisture content, and when configured in a distributed type, it includes irregular noise according to time. In this paper, an optimal calibration algorithm is designed for distributed TDR sensors establish an environment that can obtain the best results.

Factor Analysis of Intraoperative Radical Conversion During Partial Nephrectomy - Single Surgeon Experience

Dong Hwan Lee,Woo Heon Cha,Younsoo Chung,Tae Jin Kim,In Jae Lee,Byeong Do Song,Sangchul Lee,Sung Kyu Hong,Jong Jin Oh,Seok-Soo Byun 대한비뇨기종양학회 2017 대한비뇨기종양학회지 Vol.15 No.3

Purpose: Preoperative aspects and dimensions used for an anatomical (PADUA) classification is useful to predict perioperative complications and warm ischemia time. However, it remains uncertain whether PADUA classification can predict intraoperative conversion from partial nephrectomy (PN) to radical nephrectomy (RN). We evaluate whether PADUA classification parameters can predict conversion to RN during PN. Materials and Methods: We retrospectively assessed data of 593 patients who underwent open PN and robotic PN for renal tumors by a single surgeon at a single tertiary center between December 2003 and September 2017. Intraoperative conversion to RN was performed in 17 of 593 patients who initially underwent PN. We evaluated the factors influencing the surgical modalities including PN and radical conversion cases. Then, the factors significantly associated with conversion to RN were further analyzed. Results: There were no significant differences between the 2 groups in age, longitudinal location, exophytic rate, and rim or face locations of renal masses. Renal sinus involvement, urinary collecting system involvement, and renal mass size were variables that predicted radical conversion, using univariate analysis. Renal sinus involvement (odds ratio [OR], 9.075; p=0.049) and urinary collecting system involvement (OR, 3.944; p=0.029) were independent predictors of intraoperative radical conversion, using multivariate analysis. Conclusions: The PADUA classification is a useful tool to predict intraoperative conversion from PN to RN. Renal sinus involvement and urinary collecting system involvement are the best predictors of intraoperative conversion from PN to RN.