KCCH cyclotron neutron 및 60Co r-ray에 의한 인체 말초혈액 임파구의 염색체 이상측정

김성호,김태환,정인용,조철구,고경환,류성렬 대한방사선 방어학회 1992 방사선방어학회지 Vol.17 No.1

KCCH cyclotron neutron(30cCy/min) 및 ??Co γ-ray(210cGy/min)를 시험관내의 정상 인체 말초혈액임파구에 조사하여 염색체이상(dicentric 및 centric ring)을 관찰하고 이의 선량-반응관계식을 linear model(Y=K₁D+a), power-law model(Y=K₂Dⁿ), quadratic model(Y=K₃D²) 및 linear-quadratic model(Y=αD+βD²)을 사용하여 구하고 이들 model중 염색체이상의 측정치와 가장 일치하는 관계식을 근거로 하여 γ -ray에 대한 neutron의 relative biological effectiveness(RBE)를 산출하였다. 염색체 이상(dicentric plus centric ring)의 발생분포는 γ-ray의 경우 linear model(P=0.067)을 제외한 power-law model[Y=(5.81±1.96)×10??, P=0.931], quadratic model [Y=(3.91±0.09)×10?D², P=0.972] 및 linear-quadratic model [Y=(6.55±6.83)×10?D+(3.72±0.22)×10?D², P=0.922]에 적합하였다. Neutron의 경우 linear model [Y=(6.12±0.17)×10?³ D-022, P=0.987]에 가장 일치하였고 quadratic model (P<0.005)을 제외한 power-law model[Y=(2.43±0.70)×10?³D+(1.21±0.39)×10?D², P=0.415]에 비교적 적합하였다. 세포당 0.1-1.5개의 염색체이상을 나타내는 neutron의 γ-ray에 대한 RBE는 2.714±0.408이었다. The frequencies of KCCH cyclotron neutron(30cCy/min) or ??Co γ-ray(210cGy/min)-induced asymmetrical interchanges(dicentrics and centric ring) and acentric fragment(deletion) at several doses were measured in the normal human peripheral blood lymphocytes. Chromosome aberrations were scored at the first nitosis after stimulation with phytohemagglutinin. The neutron and γ-ray data were analysed on liner, power-law, quadratic and linear-quadratic model. When the dicentrics and centric rings of γ-ray datas were pooled and fitted to these model, good fits were obtained to power-law [Y=(5.81±1.96)×10??, P=0.931], quadratic [Y=(3.91±0.09)×10?D², P=0.972] 및 linear-quadratic model [Y=(6.55±6.83)×10?D+(3.72±0.22)×10?D², P=0.922] except for linear model(P=0.067). As in the case of neutron data, the best fits was obtained to the linear model [Y=(6.12±0.17)×10?³ D-022, P=0.987] and good fits were obtained to power-law[Y=(5.36±3.02)×10?⁴D??, P=0.601] and linear-quadratic model [Y=(2.43±0.70)×10?³D+(1.21±0.39)×10?D², P=0.415], except for quadratic model (P<0.005). The relative biological effectiveness(RBE) of neutron compared with γ-ray was estimated by best fitting model. In the asymmetrical interchanges range between 0.1 and 1.5 per cell, the REE was found to be 2.714±0.408.

前腕部 經穴 取穴에서 骨度分寸法과 一夫法의 比較 硏究

박히준,채윤병,차웅석,박종배,이혜정,이향숙,인창식,고형균,김수영,최일환,김강식,문정배,배기태,유경환,육근영,정병주,손인철,임사비나 WHO COLLABORATING CENTRE FOR TRADITIONAL MEDICINE 2004 東西醫學硏究所 論文集 Vol.2004 No.-

Background : The cun measurement System, an essential and convenient method in locating acupoints, has been widely used in the practice of acupuncture. However, traditional cun measurement has been criticized for its lack of reliability. Objectives : The purposes of this study are to determine if one cun measured by the directional methods have a consistency with that of proportional methods and to investigate which factors are related with these differences, especially in forearm. Methods : The distance between the elbow crease and the wrist crease of forearm was compared to a reference value of one cun obtained by the directional method. In this method, one cun is one third of the distance between index finger and Small finger of a subject, measured at proximal interphalangeal joint. In addition, to investigate the factors influencing the differences between these two methods, we measured the height and body weight and calculated body mass index (BMI). Finally we analyzed the factors correlated with these lengths by linear regression test. Results : The results showed that one cun obtained by the directional methods were significantly different from one cun by the proportional methods in forearm. It was demonstrated that the length acquired with the directional method was more correlated with body weight and body mass index, while the length obtained by the proportional method was more correlated with the height.

Korean version of Patient-rated tennis elbow evaluation questionnaire : Cross-cultural adaptation and validation

Kyoung-Hwan Koh,Hyun Il Lee,Ki Won Lee 대한견주관절의학회 2018 대한견주관절학회 학술대회논문집 Vol.2018 No.3

Complete versus incomplete footprint coverage in rotator cuff repairs

Kyoung Hwan Koh,Jae Chul Yoo 대한견주관절의학회 2013 대한견주관절학회 학술대회논문집 Vol.2013 No.3

Surgical Treatment of Olecranon Fractures

Kyoung-Hwan Koh,Hyoung-Keun Oh 대한견주관절의학회 2017 대한견주관절학회지 Vol.20 No.1

Since the olecranon fractures are caused by relatively low-energy injuries, such as a fall from standing height, they are usually found without comminution. Less commonly they can be developed by high-energy injuries and have severe concomitant comminution or injuries to surrounding structures of the elbow. Because the fracture by nature is intra-articular with the exception of some avulsion-type fracture, a majority of olecranon fractures are usually indicated for surgical treatment. Even if there is minimal displacement, surgical treatment is recommended because there is a possibility of further displacement by the traction force of triceps tendon. The most common type of olecranon fracture is displaced, simple non-comminuted fracture (that is, Mayo type IIA fractures). Although tension band wiring was the most widespread treatment method for these fractures previously, there is some trends toward fixation using locking plates. Primary goal of the surgery is to restore a congruent joint and extensor mechanisms by accurate reduction and stable fixation so that range of motion exercises can be performed. The literature has shown that good clinical outcomes are achieved irrespective of surgical fixation technique. However, since the soft tissue envelope around the elbow is poor and the implants are located at the subcutaneous layer, implant irritation is still the most common complication associated with surgical treatment.

Post-Traumatic Stiffness with Ectopic Ossification

Kyoung Hwan Koh,Tae Kang Lim,Min Jong Park 대한견주관절의학회 2011 대한견주관절학회 학술대회논문집 Vol.2011 No.3

Unhealed SCR still works and tear pattern after SCR is not simple.

Kyoung Hwan Koh,Sanghyeon Lee,Sang-Jin Shin 대한견주관절의학회 2021 대한견주관절학회 학술대회논문집 Vol.2021 No.3

Introduction and Background Superior capsular reconstruction (SCR) using autogenous tensor fascia latae has been reported excellent structural and clinical outcome. However, most of SCR other than Japan are performed with acellular dermal matrix allograft (ADM). Thus, it might lead to less favorable healing and clinical results. The purpose of this study is to show the tear pattern of SCR using ADM and investigate the correlation with clinical outcome. Material and Method From October 2017 to February 2020, 51 consecutive SCR cases in two institutions (EUSH & AMC) after inclusion and exclusion criteria were analyzed. Range-of-motion, muscle power, visual analogue scale for pain (PVAS), ASES score, and Constant score were evaluated. Achievement of minimal clinically important difference (MCID) and patient acceptable symptomatic status (PASS) of clinical scores were evaluated. Graft healing and tear pattern was evaluated on postoperative MRI. Clinical outcome according to the status of graft was compared. Results PVAS (3.8 to 0.6), ASES score (56.7 to 85.9), and Constant score (57.6 to 68.4) were improved postoperatively. Graft tear can be classified as ‘healed (intact)’, partial tear, and complete tear. 36 cases (70.6%) showed healed graft. 9 (17.6%) cases had 2 glenoid, 5 humeral, and 2 both-side partial tear. 6 (11.8%) cases revealed 5 glenoid and 1 humeral side complete tear. There was no both-side complete tear and midsubstance tear. There were no differences in rangeof-motion, muscle power, clinical scores, and satisfaction. However, odds ratio for MCID of PVAS and ASES score were different according to the graft tear, and PASS of PVAS and ASES score was affected by graft continuity. Conclusions Tear pattern in SCR using ADM is not simple and some torn SCR still works if the continuity is maintained despite the partial tear of graft.

이 연구에 적절한 통계를 적용했는가?

Kyoung Hwan Koh(고경환) 대한견주관절의학회 2015 대한견주관절학회 학술대회논문집 Vol.2015 No.4

Crossbar Technique for the Failed Clavicular Hook Plate Fixation in an Acute Acromioclavicular Joint Dislocation: Salvage for Acromial Fracture after Clavicular Hook Plate

Kyoung Hwan Koh,Dong Ju Shin,Seong Mun Hwang 대한견주관절의학회 2019 대한견주관절의학회지 Vol.22 No.3

We experienced acromial erosion and subsequent fracture after the treatment of Rockwood type V acromioclavicular dislocation with hook plate and coracoclavicular ligament augmentation. It was treated by using a surgical technique to address an acromial fracture and subsequent losses of reduction in acromioclavicular joint with two trans-acromial cortical screws (crossbar technique). The reduction state of acromioclavicular joint could be maintained by these two screws. Our crossbar technique could be considered as a good salvage procedure for the reduction loss caused by cutout or significant erosion of acromion after insertion of clavicular hook plate.

조기 유방암에서 보존적 수술후 방사선치료성적

고경환(Kyoung Hwan Koh),김미숙(Mi Sook Kim),류성렬(Seong Yul Yoo),조철구(Chul Koo Cho),김재영(Jae Young Kim),김용규(Yong Kyu Kim),문난모(Nan Mo Moon),백남선(Nam Sum Paik),이종인(Jong Inn Lee),최동욱(Dong Wook Choi) 대한방사선종양학회 1995 Radiation Oncology Journal Vol.13 No.2

목적 : 조기 유방암에서 보존적 수술후 방사선치료는 외국에서 과거 20여면 동안 근치적 수술과 비슷한 생존율을 보였다. 그러나 아직 우리 나라에서는 보편화되지는 못한 실정이다. 이 논문은 원자력병원에서 시행한 조기 유방암환자에서 보존적 수술의 성적 및 부작용의 결과를 알기 위함이다. 방법 : 1987년 1월부터 1989년 12월까지 원자력 병원 치료방사선과에서 보존적 수술후 방사선치료를 받은 조기 유방암 환자 45명에 대해 후향적 연구를 시행하였다. 추적 관찰기간은 4-82개월이었고 중앙값은 54개월이었다. 수술은 조직 생검만 시행한 경우 및 Tumorectomy 또는 Quadrantectomy를 시행한 경우가 있었다. 28예에서 액와림프절 박리를 시행하였다. 방사선치료는 전유방에 Tangential field로 하루 1.8-2 Gy씩 총 50 또는 50.4 Gy를 조사하였다. 항암요법은 30예의 환자에서 시행되었고 호르몬 치료는 11예에서 시행되었다. 결과 : 5년 생존율, 5년 무병생존율 및 5년 국소제어율은 각각 87.2%, 86.5%, 97.6%였다. 전신 요법을 시행하는 군이 시행하지 않은 군에 비하여 5년 생존율에서 좋은 성적을 보였으나 통계학적인 의미는 없었다 (0.05<p<01). 심각한 후유증은 8.9%였다. 결론 : 조기 유방암에서 보존적 수술후 방사선 치료는 근치적 수술과 비교하여 생존율 및 국소제어율에 차이가 없음을 알 수 있었다. 향후 많은 환자 수와 오랜 추적기간을 통하여 국소제어율과 미용 효과에 영향을 미치는 예후인자를 찾아 환자선택과 치료에 응용함으로 더 높은 국소제어율과 미용 효과의 증대를 꾀할 수 있으리라 사료된다. Purpose : Primary radiation therapy following breast-conserving surgery has been an accepted alternative to mastectomy during the past 2 decades. In this country, however, the practice of conservatinve therapy for early invasive breast cancer has not been generalized yet. The purpose of this report was to evaluate the results and complications of breast conservation therapy in Korean Cancer Center Hospital(KCCH). Materials and Methods : From January 1987 to December 1989. 45 patients with early breast cancer treated with conservative treatment in KCCH were studied retrospectively. Median follow up was 54 months(range, 4 to 82 months). All patients received partial mastectomy (biopsy, tumorectomy, or quadrantectomy) and radiation therapy. Twenty eight patients received axillary dissection. The breast was treated with two opposing tangential fields (total 50 Gy or 50.4 Gy in 5 weeks with daily target dose of 2 Gy or .8 Gy). Thirty patients received chemotherapy before and after radiotherapy. Eleven patients received hormonal therapy. Results : Five-year survival rate, 5-year disease free survival rate and 5-year local control rate were 87.2%, 86.5% and 97.6%, respectively. Administration of systemic Therapy (chemotherapy or hormonal therapy) correlated with good prognosis but statistically not significant (0.05<p<01). The severe late complication rate was 8.9%. Conclusion : Primary radiation therapy following breast-conserving surgery for early breast cancer is an alternative treatment comparing to radical treatment. Long term follow-up and more patients collection os needed to evaluate the prognostic factor and cosmetic outcome.