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Park, Ka-Young,Lee, Tae-Hee,Jo, Suyeon,Yang, Jayoon,Song, Sun-Ju,Lim, Hyung-Tae,Kim, Jung Hyun,Park, Jun-Young Elsevier 2016 Journal of Power Sources Vol.336 No.-
<P><B>Abstract</B></P> <P>Co-ionic (H<SUP>+</SUP>/O<SUP>2−</SUP>) electrolytes are fabricated by compositing both proton conductor (BaZr<SUB>0.85</SUB>Y<SUB>0.15</SUB>O<SUB>3-δ</SUB>, BZY) and oxygen-ion conductor (Nd<SUB>0.1</SUB>Ce<SUB>0.9</SUB>O<SUB>2−δ</SUB>, NDC) for intermediate temperature-solid oxide fuel cells (IT-SOFCs). This hybrid electrolyte decreases the electronic loss of NDC under reducing atmospheres and improves the poor sinterability of BZY. The electronic conduction caused by the NDC reduction is effectively blocked by the BZY in the composite electrolyte, thus offering both advantages of BZY with its high OCV and more rigid electro-chemo-mechanical property. In addition, the composite BZY-NDC electrolyte also exhibits great chemical stability against exposure to steam and CO<SUB>2</SUB>. Furthermore, the compositing of BZY and NDC improves the proton conductivity of the electrolytes, and the conductivity of composite electrolyte is higher than that of single BZY at temperatures >600 °C.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Co-ionic electrolyte is fabricated by compositing proton and oxygen-ion conductor. </LI> <LI> Hybrid electrolytes decrease electronic loss and improve poor sinterability. </LI> <LI> Conductivity of composite electrolyte is higher than that of single BZY at >600 °C. </LI> <LI> Composite electrolytes exhibits great chemical stability against steam and CO<SUB>2</SUB>. </LI> <LI> Mechanical stability of cells improves by preventing chemical expansion of ceria. </LI> </UL> </P>
젖산발효 처리에 의한 도라지의 Platycosides 조성 및 호흡기 질환 유발세균에 대한 항균활성 변화
Ka Soon Lee,Bong Jae Seong,Sun Ick Kim,Moo Geun Jee,Saet Byeol Park,Myeong Hee Park,Shin Young Park,Hyun Ho Kim 한국약용작물학회 2016 한국약용작물학술대회 발표집 Vol.2016 No.05
Background : Platycodon grandiflorum root(PGR) was one of the primary herbs used in a phlegm-relieving herb from the past. Purified platycoside compounds from the roots of PGR may exhibit neuroprotective, antimicrobial, anti-inflammatory, anti-cancer, anti-allergy, improved insulin resistance, and cholesterol-lowering properties. To evaluate preference and functionality of PGR extracts, PGR was fermented by several lactic acid bacteria. Lactic acid bacteria used were Leuc. mesenteroides N12-4 and N58-5, L. plantarum N76-10 and 56-12, L. brevis N70-9 and E3-8. Methods and Results : This study was performed in order to investigate the changes of platycosides, as well as the antimicrobial activities on bronchus diseases inducing bacteria(C. diphtheriae, K. pnneumoniae, S. aureus, S. pyogenes) of Platycodon grandiflorum root(PGR) fermented by using lactic acid bacteria(Leuc. mesenteroides N12-4, Leuc. mesenteroides N58-5, L. plantarum N76-10, L. plantarum N56-12, L. brevis N70-9, L. brevis E3-8). Growth of L. plantarum on PGR was the most active during lactic acid fermentation by some different strains. Total platycoside, platycoside E, platycodin A, polygalacin D2, polygalacin D and diapioplatycoside E contents of PGR fermented for 96 hours at 37℃ by Leuc. mesenteroides and L. plantarum were increased, while platycodin D and platycodin D3 were decreased. The antimicribial activity on PGR fermented by L. plantarum N56-12 exhibited a strong microbial proliferation in all four kinds of bronchus diseases inducing bacteria and was higher than non-fermented PGR extract. Conclusion : Thus, this results showed antimicrobial activities on bronchus diseases inducing bacteria and platycosides content of PGR by L. plantarum N56-12 were higher than non-fermented PGR extract.
Characterisation of Pseudomonas aeruginosa related to bovine mastitis.
Park, Hye Rim,Hong, Min Ki,Hwang, Sun Young,Park, Young Kyung,Kwon, Ka Hee,Yoon, Jang Won,Shin, Sook,Kim, Jae Hong,Park, Yong Ho Akadémiai Kiadó 2014 ACTA VETERINARIA HUNGARICA Vol.62 No.1
<P>Pseudomonas aeruginosa is one of the causative pathogens of bovine mastitis. Most P. aeruginosa strains possess the type III secretion system (TTSS), which may increase somatic cell counts (SCCs) in milk from mastitis-affected cows. Moreover, most of P. aeruginosa cells can form biofilms, thereby reducing antibiotic efficacy. In this study, the presence and effect of TTSS-related genotypes on increase of SCCs among 122 P. aeruginosa isolates obtained from raw milk samples from mastitis-affected cows and their antibiotic susceptibility at planktonic and biofilm status were investigated. Based on the presence of TTSS-related genes a total of 82.7% of the isolates were found to harbour exoU and/or exoS genes, including the invasive (exoU-/exoS+, 69.4%), cytotoxic (exoU+/exoS-, 8.3%) and cytotoxic/invasive strains (exoU+/ exoS+, 5.0%). Milk containing exoS-positive isolates had higher SCCs than those containing exoS-negative isolates. The majority of isolates showed gentamicin, amikacin, meropenem and ciprofloxacin susceptibility at planktonic status. However, the susceptibility was decreased at the biofilm status. Based on minimum biofilm eradication concentration (MBEC)/minimum inhibitory concentration (MIC) ratios, the range of change in antibiotic susceptibility varied widely depending on the antibiotics (from 3.1-fold to 475.0-fold). In conclusion, most P. aeruginosa isolates studied here had a genotype related to increase in SCCs. The efficiency of antibiotic therapy against P. aeruginosa-related bovine mastitis could be improved by analysing both the MBEC and the MIC of isolates.</P>
장기간 Furosemide 의 복용으로 발생한 신수질 석회화가 동반된 가성 Bartter 씨 증후군
박성수,박경주,박송자,박성훈,윤여학,조윤숙,채봉남,이가희,김윤구,최진용 대한내과학회 1993 대한내과학회지 Vol.45 No.2
A 30-year-old married woman showed hypokalemic metabolic alkalosis, normotensive hyperreninemia, hyperaldosteronism and a high urinary sodium and chloride level. She was thought have Bartter's syndrome because she denied taking diuretics. But all the five tests of urine for furosemide by high performance liquid chromatography (HPLC) gave positive results. On being confronted with the results of urine analysis showing the presence of furosemide, she did admit to the taking of furosemide for 11 years. Renal radiologic studies including intravenous pyelography, ultrasonography, and computed tomography showed medullary nephrocalcinosis. This case is unique in that nephrocalcinosis have been related to long term furosemide ingestion in adults and we concluded that this apparent case of Bartter's syndrome with nephrocalcinosis was caused by long term surreptitious diuretic ingestion and suggest that this may occur more frequently than is generally appreciated.