동맥경화증의 예방과 치료를 위한 영양과 운동처방

한성섭,김용재,백영호 釜山大學校 附設 體育科學硏究所 1994 體育科學硏究所 論文集 Vol.10 No.-

1) Risk factors of aterosclerosis is Hypertension, hyperlipidermia, diabetes, obesity, physical inactivity and excessive smoking. Aterosclerosis begins at young age and worsens with age, particularty more so in men than women. For people with risk factors of atherosclerosis, it is important to prevent atherosclerosis-related disease with dietary, living pattern and exercise prescription. 2) Ditary fibers promote exercise of the digestive tract and shortens the time food remains inside the digestive tract. It can prevent obesity, hyperlipidermia, aterosclerosis and colon cancer by blocking the absorption of cholesterol. Various vegetables and sea foods are rich in unsaturated fats and can act prevent the absorption of cholesterol inside the digestive tract. 3) Occurrence of Coronary Heart Disease can largely be attributed to blood serum cholesterol. Particular attention should be paid to the increase of LDL cholesterol and decrease of HDL cholesterol as risk factors(If overall cholesterol/HDL cholesterol is below 3.5, it should be brought up to just below 4.5). HDL cholesterol is a lipo-protein that prevents atherosclerosis. 4) People with blood pressure of 160mmHg/90mmHg or higher shows 5 times higher rate of occurrence of atherosclerosis-related disease than people with normal blood pressure of 140mmHg/90mmHg, and smokers of a pack a day shoes 3-5times higher rate of occurrence than non-smokers. 5) Essential fatty acids and unsaturated fats, which are contained in vegetable oils, promotes metabolism while preventing absorption. In fruits, pectin, water-soluble fiber, is present and lowers the level of cholesterol. By consuming foods that are low in cholesterol and saturated fats, and rich in unsaturated fats, aliomentotherapy alone can reduce the plasma cholesterol by 10-15%. 6) For patients with LDL cholesterol level of 190mmHg/dl or higher, or LDL level of 160mmHg/dl or higher, and two or more rusk factors, drug therapy should be considered. The LDL cholesterol level should be kept below 130mmHg/dl and, desirably lower if possible. If the patient already has coronary heart disease, LDL cholesterol should even be lowered to and kept at below 100mmHg/dl. In treating high cholesterol, it is effective to use Resin and Lovastatin together or Lovastatin in combination. 7) Regular exercise is effective in preventing coronary arterial disease such as angina pectoris and infaction, inside it can lower the blood pressure and aids in weight control and release of stress. 8) For ideal exercise, it should be aerobic with Intensity of 60-80%HRmax(50-70%VO₂max), duration of 15-60min/day. The frequency of 3-6/week is desirable the better exercise prescription is endureance aerobic exercise. To get more effect exercise, exercise consistency very important.

Two new records of the genus Nola Leach, 1815 (Lepidoptera: Nolidae, Nolinae) from Laos

Yeong–Bin Cha,Ulziijargal Bayarsaikhan,Sol–Moon Na,Dong–June Lee,Jae–Ho Ko,Tak–Gi Lee,Hyeong–Kyu Kim,Chang–Moon Jang,Han–Ul Kim,Yang–Seop Bae 한국응용곤충학회 2019 한국응용곤충학회 학술대회논문집 Vol.2019 No.04

The genus Nola (Nolidae, Nolinae) was established by Leach (1815), with the Noctua palliola Denis & Schiffermüller, 1775 (a junior subjective synonym of Phalaena cucullatella Linnaeus, 1758) from Vienna, Austria. Nola comprises over 200 species: Africa and western Palearctic approximately described 100 speices (Hacker et al., 2012); Oriental and Eastern Palearctic regions have over 100 species (László et al., 2010; Sasaki et al., 2011; Kononenko and Pinratana, 2013). Two species of the genus Nola Leach; Nola euryzonata (Hampson, 1900) and Nola lucidalis (Walker, 1865), reported for the first time in Laos. Illustrations of adults and genitalia of all the examined species are provided.

土壞 및 植物體 중 窒酸態 窒素 簡易測定 方法 探索

鄭英祥,梁在義,韓連奎,崔文憲 江原大學校 附設 環境硏究所 1996 環境硏究 Vol.13 No.-

Feasibility of simple rapid methods to determine nitrate concentration in soil and plant sap in siltu was assessed using Merckoquant strip method and Cardy NO_(3)- sensor. The saturated extract of a soil was sampled readily in field by a simple apparatus which consists of a syringe, a vial and a hand vacuum pump with a vacuum valve. The simple measurement methods for saturated extract were tested for soil samples obtained from the thirty three farm vinyl houses around Chuncheon, Kang-weon-Do and Kuri, Kyeonggi-Do. The methods were tested for soil and plant sap samples grown under different fertilization in a vinyl house at Kangweon National University. The main treatments were with or without organic fertilizer, and subtreatments were four nitrogen levels ; 0, 100, 200 and 400kg/ha for lettuce and 0, 150, 300 and 500k9/ha for cucumber. The Cardy sensor method showed a high confidence for soil and plant sap nitrate measurement. The Merckoquant strip method was also reliable, but checking electrical conductivity was recommended for better reliability. The soil nitrate concentration above 10mmo1/L was not desirable for lettuce yield, and 15mmo1/L for cucumber. The respective electrical conductivities of saturated extracts were 3 to 4ds/m at these concentrations. The soil nitrate concentration could be monitored by Amberlite IRN-150 Resin-bag. A good correlation was obtained between the soil nitrate concentration and the nitrate absorbed by the resin bag. Therefore, use of the resin bag could be recommended to monitor nitrate in soil, minimizing soil destruction.

비만의 예방과 치료를 위한 영양과 운동처방

김용재,한성섭,백영호 釜山大學校 附設 體育科學硏究所 1994 體育科學硏究所 論文集 Vol.10 No.-

1. Obesity is an excessively increased state of total body fat, and it means that body fat is much more than normalcy by exercised 20 % in men and 30% in women. The causes of obesity are genetic body, environment, lack of exercise, meal pattern, psychological and social factor. And, obesity increased the risk of body unbalance and disease. Obese individual has a more and larger adipocytes fat cell than normal individual. And the number of adipocytes fat cell increases 4 times between 1∼22 years old. Adipose tissue LPL activity is elevated in obese individual. 2. Obesity promotes the adult-disease and increase the possibility of heart disease, hepatism, Mellitus(diabetes), Hypertension and Arteriosclerosis by 15∼40%. ① As the weight of hypertensive decreases, the blood pressure decreases, on the contrary, as the former increases, the latter increases. ② After decrease of weight, blood plasma tryglyceride becomes rare. ③ obesity induces the Mellitus and has remarkable relation with overweight. ④ By the phenomena of excessive insulin structure in the state of obesity, it was proves that insulin causes insulin resistance and insensitivity 3. Respiratory problems and other diseases are the CO₂ retention problems by the lack of exercise and the occurrence of gouty attacks (in the case of30% above average weight). In men, the higher mortality was for colorectal and prostate cancer, and in women, for endometrial, gallbladder and breast cancer. 4. Because BAT(Brown Adipose Tissue) emits the heat by oxidizing the fat-acid in cell, it has an important role as a regulator of body heat and energy balance. And, it seems that BAT in intimately associated with obesity through the weight regulation. 5. The therapeutic use of exercise to reverse obesity has been widely hailed. Exercise strengthens, softens the muscles and increases the chemical action and metabolism. Weight regulation by drugs has to be accompanied by metabolism and dietary management. The strength of exercise has to be maintained 80% of maximum pulse frequency, the duration of exercise has to be sustained 15∼20minutes after 3 minutes of warming up. It is recommended that 3∼6 times of exercise a week is suitable

해역에 방출된 온배수의 거동에 관한 k-ε난류모형에 의한 3차원 계산

허재영,최한기 大田大學校 産業技術硏究所 1996 산업기술연구소 論文集 Vol.7 No.2

A 3-dimensional κ-ε 2 equation numerical model was established to investigate the behaviour of cooling water discharged into a cross-flow field. To grasp the hydrodynamic characteristics of the interaction between the cooling water and the cooling water and the cross flow, the complicated configuration of the sea bed in the Yongkwang bay was framed in the computer program, and the computations for a real-field flow condition were carried out. The rigorous comparison of the computation results with the observed data was impossible because of the poor field data, but the computation results were seemed to predict the behaviours of the cooling water approximately.

Horseshoe Appliance를 이용한 III 급 부정교합의 치험례

홍한영,박재홍,최영철,김광철 大韓小兒齒科學會 2008 大韓小兒齒科學會誌 Vol.35 No.2

성장기 아동의 치열은 대부분 혼합 치열로,이 시기에는 유치 탈락 또는 계승치 미맹출로 인해 치열에 빈 공간이 많아 지고,계승치가 맹출되었다 하더라도 고정성 장치를 부착시키고 강한 호선을 적용시키기는 매우 어렵다. 이런 치료 진행의 문제점을 해결하기 위해 horseshoe 장치가 유용하게 사용될 수 있다. 이 장치는 치열에 빈 공간이 있는지의 여부에 관계없이 장치 제작이 가능하며,치열 상태와 무관하게 전 치열을 하나로 묶어준다. 그리고 구강내에 이미 맹출된 치아의 모든 치면을 피개하므로 치아의 정출과 회전이 발생하지 않으면서 악간 고무줄의 힘에 의해 치조골의 골개조가 상악과 하악 치궁에서 서로 반대 방향으로 유도된다. 경희대학교 치대병원 소아치과에 내원한 환아에서,Horseshoe Appliance를 이용하여 III급 부정교합에서 양호한 결과를 얻었기에 보고하는 바이다. In mixed dentition there exists many empty spaces in the arch due to eruption of permanent teeth and exfoliation of primary teeth. The empty spaces makes it difficult to apply fixed orthodontic appliances. Horseshoe Appliance can be used effectively at this stage, holding the whole dentition in one piece, It covers every surface of erupted teeth and prevents extrusion and rotation of single tooth. By using intermaxillary elastic force, remodeling of the alveolar bone is opposite in each arch. In patients who were treated with horseshoe appliance, forward growth of maxilla, labioversion of maxillary incisors and linguoversion of mandibular incisors were obtained. Minimum downward and clockwise rotation of mandible was shown, so increasing anterior facial height was minimized.

銅鑛山廢水로부터 分離한 구리 耐性菌(P.stutzeri)의 菌體內 구리 蓄積 特性

許鍾秀,曺周植,韓文圭,李洪宰,林永成 경상대학교 환경보전연구소 1994 環境保全硏究所報 Vol.2 No.1

Of the copper-tolerant 215 bacterial strains isolated from polluted river water, wastewater and activated sludges of wastewater treatment plants, or wastewater and soils of the copper mine aera in Gyeongnam province a strain, which showed considerably higher growth rate in the agar plate containing 2000ppm of copper than any other strains, was identified as a Pseudomonas stutzeri or its similar strain when analyzed by taxonomical charicteristics. Optimum pH and temperature for the growth of the P. stutzeri were 7.0 and 30℃ respectively. This strain was resistant to antibiotics, such as ampicillin and tetracycline, and heavy metals, such as lead and chromium. This strain utilized phenol benzen or toluene as a sole carbon source. The rate of copper accumulation in P. stutzeri cell was enhanced at low concentration of Cu in the growth media. The maximum copper absorption by this strain grown in 10ppm of Cu at 3 days after culture was 49%, but in 50ppm and 100ppm of Cu was 38% and 32%, respectively. The optimal temprature and pH for the effective intracellular accumulation of copper were 30℃ and initial pH 8.0 under shaking culture.

김치가 노화촉진쥐 뇌의 유리기 생성 및 항산화효소 활성에 미치는 영향

김종현,류재두,이한기,박정희,문갑순,최홍식,송영옥 부산대학교 김치연구소 2002 김치의 과학과 기술 Vol.8 No.-

본 연구는 김치가 노화와 직접적인 관련이 있는 유리기 생성 및 항산화 효소활성에 미치는 영향을 살펴보기 위하여 배추김치, 배추갓김치 그리고 갓김치를 식이중량의 5% 첨가하여 실험식이를 제조하여 이를 노화촉진쥐인 SAMP8에게 1년간 섭취시켰다. 총유리기, OH radical, H_2O_2농도 그리고 TBARS 농도 모두 가령에 따라 증가하였으며, 김치섭취시 유의적으로 감소되었다(p<0.05), 김치군에 있어서 생성된 유리기를 제거하기 위해 항산화계 효소인 SOD, catalase, GSH-px 그리고 GSH/GSSG는 모든 김치군에서 유의적으로 증가 하였다(P<0.05). 따라서 김치섭취는 먼저 가령에 의해 생성되는 유리기의 생성은 억제시키면서, 둘째 이를 제거하기 위한 항산화계 효소 활성은 더욱 활성화시키므로써 항노화 기능을 발휘한다고 생각된다. 김치종류 중에서는 배추갓김치와 갓김치가 배추김치보다 유리기 생성을 억제하고, 항산화계 활성을 증진시킨 것으로 보아 이들의 항노화 효과가 클것으로 생각된다. This study was performed to investigate the effect of kimchi intake on antiaging characteristics in the brain of senescence-accelerated mouse (SAM) in terms of free radical production and anti-oxidative enzymes. Two hundreds twenty SAM (20 mice) were divided into four groups and fed kimchi diet for 12 months. Experimental groups were kimchi free AIN-76 diet (control) group, Korean cabbage kimchi diet (KCK)group, 30% mustard leaf added Korean cabbage kimchi diet (MKCK) group, and mustard leaf kimchi diet (MLK) group. Concentrations of total free radical, OH radical and H_2O_2 of control group increased up to 123%, 262% and 174% of initial value (p<0.05) after one year. Increase in free radical production in kimchi groups due to aging was decreased by kimchi feeding. Among kimchi groups. MKCK and MLK groups showed greater inhibiting effect against free radical production than KCK. The concentration of TBARS in the bruin of control group also significantly increased up to 362% of initial value as aged (p<0.05) and production of TBARS in kimchi groups were decreased. When the activities of Cu, Zn-SOD, Mn-SOD, GSH-px and catalase of kimchi groups were compared to those of control at the same experimental period, anti-oxidative enzyme activities of kimchi groups were lower than those of control (p<0.05). But GSH/GSSG in kimchi groups were higher compared to control. In conclusion, decrease in free radical production and increase in anti-oxidative enzyme activities were observed from kimchi groups suggesting that kimchi might have important role on retarding aging. Among kimchi variety tested in this experiment, MKCK and MLK seem to have greater effect on inhibiting free radical production and increasing anti-oxidative enzyme activities than KCK.

장기 이식 환자에서 Voriconazole 과 Cyclosporine 또는 Tacrolimus의 상호작용

한혜원,김재연,송영천,김승은,유성길 한국병원약사회 2009 병원약사회지 Vol.26 No.1

Abstract: In organ transplant patients, the opportunity of fungi infections such as invasive aspergillosis increase by use of immunosuppresant drugs and voriconazole is recommended as primary treatment drug. When voriconazole is administered with cyclosporine(CsA) or tacrolimus(FK506), caution about increment of blood CsA or FK506 concentrations that caused by the change of CYP3A4 activity is required but few domestic cases of interaction were reported yet, The purpose of this study was to assess the effect of voriconazole on the blood CsA or FK506 concentrations in transplant recipients and the factors of recipients that have an effect on the results. 25 transplant recipients who were administered voriconazole with CsA or FK506 from January 1 of 2006 to August 17 of 2008 in Asan Medical Center were objects (12 patients on CsA coadministration arm - 9 males, 3 females; 41~62years;2 liver, 2 kidney, 3 bone marrow, 5 heart transplant recipients, and 13 on FK506 coadministration arm - 7 males, 6 females;26~65years; 10 liver, 2 kidney, 1 heart transplant recipients). Blood CsA or FK506 concentrations before and after coadministration of voriconazole, and maximum concentration in one month from the first day of coadministration were monitored retrospectively. In most cases CsA or FK506 were administered as recommended doses regardless of coadministration of voriconazole, and blood concentration increased from 239.42±126. 77ng/ml to maximum 411.92±225. 76ng/ml in CsA coadministration arm(p=0.003), and from 7.72±2.79ng/ml to maximum 19.16±9.35ng/ml in FK506 coadministration arm(p=0.003). Gender, age, and the kind of transplant organ did not affect to the change of blood concentration in both two arms. In consequences, administration of voriconazole could affect on the blood CsA or FK506 concentration, and in cases of administra tion of voriconazole in transplant recipients treated with CsA or FK506, close monitoring and dose adjustment is needed.

구리 耐性菌(Pseudomonas stutzeri)의 菌體內 구리 蓄積機作

許鍾秀,曺周植,韓文圭,李洪宰,林永成 경상대학교 환경보전연구소 1994 環境保全硏究所報 Vol.2 No.1

In order to study the mechanism of the copper accumulation in the cell of copper-tolerant bacterium, Pseudomonas stutzeri, distribution of the copper in the cell were investigated. Approximately 61% of the accumulated copper was distributed on the cell wall and the other 39% portion was in cytoplasm. 78% of the copper in the cell wall fractions was present in the polyphosphate and polysaccharide fractions, but most of copper in the cytoplasm fractions was in protein and nucleic acid. Copper affected the protein synthesis in P. stutzeri. The intracellular protein content was decreased by copper addition, but the soluble protein precipitated by ammonium sulfate(30-75% saturation) was increased as compared to that from the cells grown without copper. Furthermore, in the cells grown with copper, high-molecular-weight soluble protein was increased, compared with the cells grown without copper, but low-molecular -weight soluble protein was decreased. These results indicate that copper inhibited the intracellular protein biosynthesis but enhanced the biosynthesis of the high-molecular-weight soluble protein precipitated by ammonium sulfate(30-75% saturation).