혈액투석 환자에게서 발생한 재생불량성 빈혈 1예

정지용,윤나라,강대웅,오종찬,장재현,선길홍,박경희,정종훈,김현리 朝鮮大學校 附設 醫學硏究所 2005 The Medical Journal of Chosun University Vol.30 No.1

Aplastic anemia is a disease characterized by pancytopenia in the peripheral blood and hypocellular bone marrow with the fatty infiltration. The causes of the acquired aplastic anemia were usually related to drugs and immune-related diseases. A 34-years old man was admitted due to general weakness. He has been going hemodialysis for 2 years because of end stage renal disease (ESRD) due to chronic glomerulonephritis. At admission, laboratory tests showed hemoglobin 6.2 g/dL, hematocrit 18.0 %, WBC 5,710mm (neutrophil 71.8%, lymphocyte 19.1%, monocyte 5.9%), reticulocyte 1.9%, platelet 93,000/mm, Fe 12.8 ug/dL, TIBC 204 ug/dL, ferritin 941.47 ng /ml, haptoglobin 0.72 g/L, vitamin B12 508.17 pmol/L, folate 24 ng/mL, total protein 6.54 g/dL, albumin 3.76 g/dL, Alk. pohsphatase 79 IU/L, AST 30.0 IU/L, ALT 39.7 IU/L, total bilirubin 0.57 mg/dl, BUN 79.4 mg/dl and creatinine 10.18 mg/dl. Peripheral blood smear showed the normocytic normochromic anemia with anisocytosis. Anemia was diagnosed but it was irresponsive to the recombinant human erythropoietin (EPO) and blood transfusion. In the bone marrow aspiration smear were there the hypoplastic myeloid and erythroid precursors. The bone marrow biopsy section showed the hypoplasia of all components (10-20%) and the fatty infiltration. We have experienced one case of the idiopathic aplastic anemia in a patient going through hemodialysis and we just report it with documentary records. 저자들은 혈액 투석 중인 환자에서 약물, 면역계 이상등의 원인을 발견할 수 없었음에도 재생 불량성 빈혈이 발생한 1예를 경험하여 문헌 고찰과 함께 보고하는 바이다.

다공질 규소의 라만 산란

김태균,김영유,서영석,조창호,나훈균 公州大學校 基礎科學硏究所 1998 自然科學硏究 Vol.7 No.-

양극반응 전류밀도를 변화시키면서 다공질 규소를 제작하여 라만산란을 관측하였다. 전류밀도가 증가함에 따라 라만신호는 520.5㎝-₁에서 멀어졌으며, 봉우리의 반치폭이 증가하였다. 또한 전류밀도 증가에 따라 원통형 다공질 결정의 직경은 감소함이 계산되었으며, 길이가 길어짐을 AFM으로 관찰하였다. The Raman scattering was studied from the porous silicons which were made by changing anodization current. As the current density was increased, it was observed that Raman was gradually far from the value of 520.5 cm￣¹and the full width half maximum increased. The decrease of radius of cylindrical porous crystal was calculated and the increase of its length was investigated through AFM.

Risk Factors for the Development and Progression of Atlantoaxial Subluxation in Surgically Treated Rheumatoid Arthritis Patients, Considering the Time Interval between Rheumatoid Arthritis Diagnosis and Surgery

Na, Min-Kyun,Chun, Hyoung-Joon,Bak, Koang-Hum,Yi, Hyeong-Joong,Ryu, Je Il,Han, Myung-Hoon The Korean Neurosurgical Society 2016 Journal of Korean neurosurgical society Vol.59 No.6

Objective : Rheumatoid arthritis (RA) is a systemic disease that can affect the cervical spine, especially the atlantoaxial region. The present study evaluated the risk factors for atlantoaxial subluxation (AAS) development and progression in patients who have undergone surgical treatment. Methods : We retrospectively analyzed the data of 62 patients with RA and surgically treated AAS between 2002 and 2015. Additionally, we identified 62 patients as controls using propensity score matching of sex and age among 12667 RA patients from a rheumatology registry between 2007 and 2015. We extracted patient data, including sex, age at diagnosis, age at surgery, disease duration, radiographic hand joint changes, and history of methotrexate use, and laboratory data, including presence of rheumatoid factor and the C-reactive protein (CRP) level. Results : The mean patient age at diagnosis was 38.0 years. The mean time interval between RA diagnosis and AAS surgery was $13.6{\pm}7.0$ years. The risk factors for surgically treated AAS development were the serum CRP level (p=0.005) and radiographic hand joint erosion (p=0.009). The risk factors for AAS progression were a short time interval between RA diagnosis and radiographic hand joint erosion (p<0.001) and young age at RA diagnosis (p=0.04). Conclusion : The CRP level at RA diagnosis and a short time interval between RA diagnosis and radiographic hand joint erosion might be risk factors for surgically treated AAS development in RA patients. Additionally, a short time interval between RA diagnosis and radiographic hand joint erosion and young age at RA diagnosis might be risk factors for AAS progression.

Desmoplastic fibroma : 1례 보고 A Case Report

나춘균,조태환,정남진,이한구,이상훈,함의근 최신의학사 1987 最新醫學 Vol.30 No.7

Treatment of a Duodenal Variceal Bleeding by Transjugular Intrahepatic Portosystemic Shunt

( Tae Hoon Kim ),( Soo-young Na ),( Seung Kyun Na ),( Eun Kwang Choi ),( Byung-cheol Song ) 대한간학회 2018 춘·추계 학술대회 (KASL) Vol.2018 No.1

Aims: Bleeding from duodenal varix is a rare complication of portal hypertension but potentially serious and can cause massive gastrointestinal bleeding. Because of the low incidence of cases, most effective treatment methods have not been established. Methods: This is a case report of successful treatment of duodenal variceal bleeding by transjugular intrahepatic portosystemic shunt (TIPS). Results: Case: A 61 year old male was admitted to hospital due to hematemesis and melena. He had been diagnosed with alcoholic liver cirrhosis 10 years ago. Six years ago, he had experienced gastric variceal bleeding, which was treated by balloon-occluded retrograde transvenous obliteration (BRTO). At presentation, vital signs were as follows: blood pressure 148/70 mm Hg, heart rate 89 bpm, temperature 36.5°C and saturation > 98%. Digital rectal examination showed fresh blood. Initial laboratory results as follows: hemoglobin (Hb) 6.5 g/dL, WBC 8.3 x103/mL, platelet 174x103/mL. The patients received terlipressin and broad-spectrum antibiotics. Esophagogastroduodenoscopy was performed on the day of admission. It showed grade 1 esophageal varices without any stigma of recent bleeding (Fig. A). The stomach showed only previous BRTO-induced scar on fundus. Duodenum was evaluated up to 2nd portion, there was no evidence of old or recent bleeding. There was no evidence of bleeding focus on the colonoscopy which was performed on the on the next day. He remained stable for 2 days even though melena persisted. At 3 days after admission, hematochezia developed again and blood pressure drop to 108/60. Gastrointestinal bleeding CT scan was performed immediately and showed venous dilatation on 3rd portion of duodenum (Fig. B). We performed esophagogastroduodenoscopy again, which showed stigma of recent bleeding from duodenal varices on the 3rd portion (Fig. C). We have successfully treated a patient with duodenal variceal bleeding by TIPS (Fig. D). Conclusions: This case brings further evidence that duodenal variceal bleeding can be treated with TIPS.

Usefulness of C-Reactive Protein as a Disease Activity Marker in Crohn`s Disease according to the Location of Disease

( Dong Hoon Yang ),( Suk Kyun Yang ),( Sang Hyoung Park ),( Ho Su Lee ),( Sun Jin Boo ),( Jae Ho Park ),( Soo Young Na ),( Kee Wook Jung ),( Kyung Jo Kim ),( Byong Duk Ye ),( Jeong Sik Byeon ),( Seung 대한소화기학회 2015 Gut and Liver Vol.9 No.1

Background/Aims: C reactive protein (CRP) is a serologic activity marker in Crohn`s disease (CD), but it may be less useful in evaluating CD activity in ileal CD patients. We aimed to investigate the usefulness of CRP as a disease activity marker in CD according to disease location. Methods: Korean CD patients in a single hospital were evaluated. Factors associated with elevated CRP concentration at the time of diagnosis of CD and the association between the physician`s prediction regarding upcoming surgery and the sites of the lesions directly related to surgery were analyzed. Results: Of 435 CD patients, 25.7%, 6.9%, and 67.4% had ileal, colonic, and ileocolonic CD, respectively. Multivariate analysis revealed that an elevated erythrocyte sedimentation rate, reduced serum albumin, CD activity index (CDAI) >220, and ileocolonic/colonic location were associated with an elevated CRP level and that the CRP level was significantly correlated with the CDAI in all CD patients (γ=0.466, p<0.01). However, the correlation coefficient was dependent on the location, with values of 0.395, 0.456, and 0.527 in patients with an ileal, ileocolonic, and colonic disease location, respectively. Surgery for ileal lesions was less predictable than surgery for ileocolonic or colonic lesions during follow up. Conclusions: CRP is less useful as a disease activity marker in patients with ileal CD than those with ileocolonic or colonic CD. (Gut Liver 2015;9:80 86)

Cold Stretching 압력용기용 ASS304 소재의 극저온 인장 및 피로거동

최훈석(Hoon Seok Choi),김재훈(Jae Hoon Kim),나성현(Seong Hyun Na),이윤형(Youn Hyung Lee),김성훈(Sung Hun Kim),김영균(Young Kyun Kim),김기동(Ki Dong Kim) 대한기계학회 2016 大韓機械學會論文集A Vol.40 No.5

ASS304 소재로 제작된 cold stretching 압력용기는 극저온 액화천연가스의 운반 및 저장에 이용된다. Cold stretching 압력용기는 특정 수압을 이용하여 허용응력까지 기존의 압력용기를 신장시킴으로써 재료에 상당량의 소성변형이 나타난다. 이 경우, ASS304 소재의 특성에 따라 소성변형 후 항복강도가 증가하며, 신장량에 따라 두께가 감소한다. 따라서 강도 및 무게측면에서 기존의 압력용기 대비 높은 효율을 나타낸다. 본 연구에서는 ASME 코드에 의거하여 제작된 소형 cold stretching 압력용기에서 직접 채취한 시편을 이용하여 극저온 인장 및 피로특성을 평가하였다. 또한 저온피로시험으로부터 획득한 S-N 선도를 통계적으로 접근하여 P-S-N 선도를 작성하였으며, SEM 을 이용하여 파단면을 분석하였다. Cold stretching(CS) pressure vessels from ASS304 (austenitic stainless steel 304) are used for the transportation and storage of liquefied natural gas(LNG). CS pressure vessels are manufactured by pressurizing the finished vessels to a specific pressure to produce the required stress σk. After CS, there is some degree of plastic deformation. Therefore, CS vessels have a higher strength and lighter weight compared to conventional vessels. In this study, we investigate the tensile and fatigue behavior of ASS304 sampled by CS pressure vessels in accordance with the ASME code at cryogenic temperature. From the fatigue test results, we show S-N curves using a statistical method recommended by JSEM-S002. We carried out the fractography of fractured specimens using scanning electron microscopy (SEM).

자속제어법에 의한 유도전동기 고효율 운전에 관한 연구

황락훈(Lak-Hoon Hwang),이춘상(Chun-Sang Lee),나승권(Sung-Kyun Na),조문택(Moon-Taek Cho) 전력전자학회 1999 전력전자학술대회 논문집 Vol.- No.-

In this paper, a vector control have been achieved by flux distribution into two axis components in d-q plane, It is a set U, V and W axis by output voltage pattern of PWM inverter, a generating flus by its output voltage changed into three axis components,At the induction -motor driving by inverter, it have already detected to fluxlinkage variation quantity and phase angle from input frequency, we proposed a software strategy of flux control algorithm that the flux vector tracing circle locus is decided as actual fluxlinkage trace reference flux,' By control algorithm reference fluxlinkage average toward direction become an axis direction induction motor is controlled flux control of stop or advance by software process<br/> This algorithm is a simplification of control circuit, ability on expressing every control parameter as quantization, compensation of quantization compensation of quantization error, a switching pattern is decided by addition and substraction.

5G mmWave 통신을 위한 딥 러닝 기반 전송 제어 프로토콜

나웅수(Woongsoo Na) 한국정보과학회 2022 정보과학회지 Vol.40 No.1

톱밥 입경에 따른 음식물류 폐기물의 퇴비화 특성 비교

고광균(Kwang-Kyun Ko),염경래(Kyung-Rai Yeom),김하나(Ha-na Kim),이창훈(Chang-Hoon Lee),김성철(Sung-Chul Kim),오택근(Taek-Keun Oh) 한국토양비료학회 2016 한국토양비료학회 학술발표회 초록집 Vol.2016 No.3