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김용배,장원기,황보영,김화성,안규동,이병국,이용진,이남수,이상건,이상범,이상우,이선정,이성수 순천향대학교 2006 Journal of Soonchunhyang Medical Science Vol.12 No.1
Objective : As the average lifespan of human increases, osteoporosis and osteoporosis-related fractures have become major health care problems. Despite recent advances in medical treatment, few studies have assessed the recognition of osteoporosis in general adults. This study examined the recognition of osteoporosis and analyzed the relating factors. Method : A population-based sample of 1086 adults in Asan-city, Korea was investigated with questionnaires and height, weight, Information regarding the general characteristics(gender, age, economic state), lifestylef exercise, smoking, alcohol),medical history(progestin, GH, steroid, calcitonin, PTH), demographic parameter, obesity, stress, and family history was collected through an interview using a structural questionnaire. The level of obesity was measured by the body mass index(BMI). BMD(Bone mineral density) at the lumbar spine and femoral neck was measured by dual energy X-ray absorptiometry. Osteoporosis was considered to be T-score below -2.5. Results : The prevalence of osteoporosis increased progressively with age, decreased with BMI and predominant in women by the result of x^(2) -test, T-test. Age, weight, BMI were significantly correlated with osteoporosis by the result of Pearson correlation ana1ysis(P<0.05). And age, gender, BMI, family history of osteoporosis were proved to be significant risk factors of osteoporosis by the result of multiple logistic regression(P<0.05). Conclusion : These results suggest that age, gender, BMI might be the most important risk factors of osteoporosis. And the history taking about family history of osteoporosis is helpful for diagnosing osteoporosis.
Kim, Gi-Young,Park, Joung-Eon,Park, Hyung-Sik,Nam, Byung-Hyouk,An, Won-Gun,Lee, Tae-Ho,Lee, Jae-Dong 부산대학교 유전공학연구소 2001 분자생물학 연구보 Vol.17 No.-
The phylogenetic tree displayed the presence of five groups in the Phellinus genus, which distinguished based on their morphology. Most of the P. linteus appeared a cluster which was highly significant with the exception of P. linteus KACC 500122 and KACC 500411. They formed the sister taxa of P. linteus where P. baumii, Phellinus sp. MPNU 7003, MPNU 7007, and MPNU 7010 had similar morphological characteristics. Also, P. nigricans IMSNU 32024 and P. pini var. carniformans IMSNU 32031 were grouped in the same cluster with P. igniarius KCTC 6227, KCTC 6228, and P. chrysoloma KCTC 6225 extracted from the Gen-Bank database. P. torulosus IMSNU 32028 and Phellinus sp. MPNU 7011 formed a closed group, however, these species had a distant taxa when compared with the other Phellinus species. The nucleotide sequences of the internal transcribed spacer (ITS) regions of ribosomal DNA (rDNA) including the 5.8S rDNA were determined from 24 strains of the Phellinus genus in order to analyze their phylogenetic relationship. These fungi were divided into two basic groups based on their ITS length, however, this grouping was different from that based on their morphological characteristics. Although, various ITS sequences were ambiguously aligned, conserved sites were also identified. Accordingly, a neighborjoining tree was constructed using the nucleotide sequenc data of the conserved sites of the ITS regions and the 5.8S rDNA.
이장명,Gi-Gun Nam,Bong-Ki Lee,Jang-Myung Lee 한국항해항만학회 2004 한국항해항만학회지 Vol.28 No.4
This paper introduces a novel approach that can provide the three dimensional information about the movement of a spreader by using two CCD cameras and a laser distance measuring unit in order to derive ALS (Automatic Landing System) in the crane used at a harbor. So far a kind of 2D Laser scanner sensor or laser distance measuring units are used as corner detectors for the geometrical matching between the spreader and a container. Such systems provide only two dimensional information which is not enough for an accurate and fast ALS. In addition to this deficiency in performance, the price of the system is too high to adapt to the ALS. Therefore, to overcome these defects, we proposed a novel method to acquire the three dimensional spreader information using two CCD cameras and a laser distance measuring unit. To show the efficiency of proposed method, real experiments are performed to show the improvement of accuracy in distance measurement by fusing the sensory information of the CCD cameras and a laser distance measuring unit.
Association of miR-34a, miR-130a, miR-150 and miR-155 polymorphisms with the risk of ischemic stroke
CHOI, GUN HO,KO, KI HAN,KIM, JUNG OH,KIM, JINKWON,OH, SEUNG HUN,HAN, IN BO,CHO, KYUNG GI,KIM, OK JOON,BAE, JINKUN,KIM, NAM KEUN Spandidos Publications 2016 INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE Vol.38 No.1
<P>MicroRNAs (miRNAs or miRs) are small (19-23 nt) non-coding RNA molecules that are endogenous regulators of gene expression. Previous studies have found that some miRNAs are related to the progression of ischemia in the cerebral artery. Furthermore, a recent study found a significant association between miRNA single nucleotide polymorphisms (SNPs) and the risk of ischemic stroke. Therefore, it may be valuable to investigate associations between megakaryocyte formation-related miRNA polymorphisms and the prevalence of ischemic stroke. We thus conducted a case-control study of 1,000 individuals who were screened for 4 miRNA polymorphisms (miR-34a rs6577555C>A, miR-130a rs731384C>T, miR-150 rs73056059G>A and miR-155 rs767649T>A) by PCR-RFLP analysis. The study population comprised 596 patients with ischemic stroke and 404 control subjects without any history of neurological disorders. We observed associations between miRNA polymorphisms and individual stroke subtypes. The miR-150 polymorphisms were significantly associated with ischemic stroke subgroups, such as left anterior descending artery (LAD) disease [GG vs. AA: adjusted odds ratio (AOR), 1.922; 95% confidence interval (CI), 1.003-3.681] and cardioembolism (GG vs. AA: AOR, 2.996; 95% CI, 1.293-6.939). Additionally, Cox proportional analysis indicated that the miR-150GA genotype was associated with survival in patients with ischemic stroke [adjusted hazard ratio (HR), 2.063; 95% CI, 1.142-3.727; P=0.017] and with the LAD subgroup [adjusted HR, 3.021; 95% CI, 1.345-6.785; P=0.008]. Our findings suggest that miR-150 polymorphisms may contribute to the development of ischemic stroke and may potentially act as biomarkers to predict the risk of ischemic stroke. To the best of our knowledge, this is the first study to evaluate the association between miRNA polymorphisms (miR-34aC>A, miR-130aC>T, miR-150G>A and miR-155T>A) and ischemic stroke.</P>
김종근 ( Chong Gun Kim ),박철우 ( Cheul Woo Park ),윤태호 ( Tae Ho Yoon ),임남기 ( Nam Gi Lim ) 한국목재공학회 2013 목재공학 Vol.41 No.3
목조주택의 골조 및 실내·외 마감용으로 사용되는 침엽수 구조재를 대상으로 방염·방충 보존처리제가 혼합된 약제에 마이크로파 가열 후 열기를 지닌체 침지하여 복합적인 기능화를 부여한 후 목재의 건조 스케줄, 방염 시험에 의한 화재 저항성과 흰개미에 의한 내충해성, 혼합 약제의 침투성 분석을 실시한 결과 마이크로파로 3kW로 5분 급속 가열된 시험편은 목표 온도 및 함수율을 만족하는 것으로 나타났으며, 인산염과 헤테로고리화합물계가 혼합된 약제에 120분 침지할 경우 가장 높은 중량 증가율을 가지는 것으로 나타났다. 또한 방염 후 처리 물품 시험을 실시한 결과 인산염과 혼합된 약제는 방염기준을 모두 만족하는 것으로 나타났으며, 흰개미 투입후 7일 사충율을 확인한 결과 인산염과 헤테로고리화합물계 혼합 약제 침투 시험편의 경우 96% 이상 높은 사충율을 나타냄으로서 가장 우수한 특성을 가지는 것으로 나타났다. 목재 내부로 약제 침투성 분석을 실시한 결과 목재 세포내부 전면에 있어 혼합약제가 침투된 것으로 나타나 목재의 방염성 및 방충 저항성 등에서 우수한 성능의 발현은 혼합 약제의 균일한 침투때문으로 판단된다. It was found that test piece heated rapidly by 3 kW microwave for 5 minutes satisfies the targeted temperature and the percentage of moisture content, and the highest rate of weight increase is obtained in case of 120 minute immersion in the mixture of phosphates and heterocyclic compounds, from the result of such analysis as: kiln drying schedule, flame retardent by flammability test, insect resistance by termites, and permeability of combined penetrant for the wood after assigning multifunctional finish by immersing conifer structural frame, which is used for the frame work of wooden house and indoor/outdoor finishing in flame retardant and insect repellent materials mixture with the remaining heat of microwave. In addition, after a test of flame retardent treated item, it was identified that every mixture of phosphates corresponds with the standards of flame retardent, and upon investigation of moritality of 7 days after putting termites, it was showed that test piece immersed in the mixture of phosphates and heterocyclic compounds has the best characteristics, showing over 96% of high moritality. From the analysis of inward permeability of combined penetrant for the wood, it was decided that excellent performance in the flame retardent and insect resistance of the wood revealed due to full penetration of combined penetrant as it was found that combined penetrant penetrated through the whole inner cells of the wood.