우리나라 시 · 군 · 구 지역보건의료계획의 비전(Vision) 문구 분석

안치영(Chi-Young Ahn),김현수(Hyun-Soo Kim),김원빈(Won-bin Kim),오창훈(Chang-hoon Oh),홍지영(Jee-Young Hong),김은영(Eun-Young Kim),이무식(Moo-Sik Lee) 한국농촌의학 지역보건학회 2017 농촌의학·지역보건 Vol.42 No.1

지역보건의료계획서에서 비전은 각 지역의 보건의료계획을 나타내는 핵심요소임에도 불구하고 작성방법에 대한 구체적인 지침이 부재하여 각 지역의 비전은 매우 다양하게 표현되어 있다. 이에 이 연구에서는 제6기 지역보건의료계획에서 제시한 비전 문구를 보건소 유형별, 권역별로 분석하였다. 전국 229개 지역의 제6기 지역보건의료계획서의 비전 문구와 이와 관련된 미션, 전략체계도, 중장기 추진과제 등을 대상으로 하였다. 지역을 권역별 4개, 읍·면·동 구성에 따른 보건소 유형을 4개로 분류하였고, 각 지역 비전의 글자 수, 문장 평가, 단어 빈도, 문구 평가를 빈도분석과 카이제곱검정, 일원배치분산분석을 이용하여 분석하였다. 비전의 글자 수가 17자 이하인 보건소가 172개소(75.1%)였고, 보건소 유형별로 유의한 차이가 있었다(p<0.05). 문구에 대한 수사표현에서 비유법(37.1%)이, 한글 외에 표현 언어 사용에서는 특수문자(43.2%)가 많았으며, 보건소 유형별로 유의한 차이가 있었다(p<0.01). 비전에 사용된 단어들은 ‘건강’, ‘행복’, ‘함께’, ‘군민’ 또는 ‘시민’, ‘도시’, ‘100세’ 등이었다. 문구평가 점수에서는 특·광역시 및 수도권에서 가장 높았으며, 보건소 유형 및 권역별로 유의한 차이를 보였다(p<0.05). 보건소 유형별로 과정 및 평가 영역, 공유가능성 등에서 유의한 차이가 있었다(p<0.01). 방향성은 충청권, 수도권 순으로 권역별로 유의한 차이가 있었으며(p<0.01), 미래지향성 및 공유가능성은 영남권이 가장 높아 권역별로 유의한 차이가 있었다(p<0.01). 비전은 지역보건의료계획에 가장 중요 요소 중 하나이다. 이 연구는 지역사회 특성별로 비전의 설정이 다름을 확인하였으며, 이러한 결과를 통하여 지역보건의료계획 등 보건소 비전 수립시 참고가 될 수 있는 기초적인 자료가 될 것으로 판단된다. Objectives: In this study, we analyzed vision statements of the 6th community health plan of local government in Korea. Methods: We examined vision statements letters, missions and strategy plans, and long-term missions of 6th community health plans of 229 local government in Korea. We also analyzed the numbers of vision letters, sentence examination, word frequency, each vision statement with frequency analysis, chi-square test, and one-way ANOVA. Results: Among 229 local government, 172(75.1%) of local government had the number of letters (Korean) less than 17 of vision statements, and there were a significant differences according to type of community health centers (p<0.05). Figuration (37.1%) were the most used in an expression of vision statement sentence, and special characters (43.2%) were the most used language except Korean. The most commonly used words of vision statement in order of frequency were ‘health’, ‘happiness’, ‘with’, ‘citizen’, ‘city’, ‘100 years old’ etc. Chungcheong provinces and Daejeon metropolitan city had a highest score in directionality on phrase evaluation, and there were a significant differences according to regional classes of local government (p<0.01). Gyeongsang provinces, Ulsan, Daegu, and Busan metropolitan cities had a highest score in future orientation and sharing possibilities on phrase evaluation, and there were a significant differences according to regional classes of local government (p<0.01). Conclusions: Vision is one of the most important component of community health plan. We need more detailed ‘vision statement guideline’ and the community health care centers of local government should effort to make more clear and complete their vision.

알코올 의존과 후보 유전자들간의 연관성 연구

정인원,김헌,홍주봉,지경환,이규영 大韓神經精神醫學會 2002 신경정신의학 Vol.41 No.6

연구목적 : 알코올 대사와 중추신경계내의 알코올 작용부위와 관련한 일부 후보유전자들이 알코올 의존과 관련이 있는지를 확인하고자 하였다. 방 법 : DSM-IV로 진단된 알코올 의존 환자 128명과 정상 대조군 128명을 대상으로 후보 유전자들의 다형성을 중합효소 연쇄반응과 제한효소처리법을 이용하여 동정하였다. 여기서 분리된 대립유전자와 유전자형에 따른 빈도의 차이를 유전자별로 각각 비교하였으며, 알코올 의존에 작용하는 서로 다른 유전자들에 의한 영향력을 배제하기 위하여 logistic regression 분석을 적용하였다. 결 과 : 알코올 의존군에서는 ALDH_2 유전자의 NN(wild type)형이 정상대조군에 비하여 유의하게 많았다(chi-square test, p<0.001). logistic regression analysis를 통하여 다른 유전자들에 의한 영향을 보정한 상태에서 ALDH_2가 NN(wild type)인 경우 다른 아형에 비하여 알코올 의존에 대한 odds ratio는 130.312이며 그 신뢰구간은 (17.22, 986.43)이었다. 한편, ASA는 N-glycosylation 부위에 변이형 대립유전자를 갖고 있는 경우(AG or GG)는 wild type에 비하여 알코올 의존에 대한 위험도는 2.344배이며 그 95% 신뢰구간은 (1.128, 4.871)이었다. 결 론 : 알코올 의존과 ALDH_2 유전자간에는 밀접한 연관성이 확인되었다. 또한 다른 유전자들은 개별 연관분석에서 의미있는 연관성이 관찰되지는 않았지만 logistic regression analysis를 통하여 N-glycosylation 부위에 다형성이 있는 ASA 유전자가 알코올 의존과 관련이 있음을 시사하였다. Objectives : This study was to explore the association between alcohol dependence and five candidate genes related to the metabolism of alcohol and the enzymes of the suspected sites in CNS. Methods : The genotype and allele frequencies of five candidate genes in 128 male hospitalized patients who met DSM-IV criteria for alcohol dependence were compared with 128 age-matched healthy male control subjects using polymerase chain reaction and restriction fragment length polymorphism. A logistic regression analysis was applied in order to exclude the reciprocal interactions among five candidate genes. Results : The NN genotype frequency of the ALDH_2 gene was significantly higher in alcoholic patients than in control subjects(chi-square test, p<0.001). No difference in frequency was found in the other four genes. In a logistic regression analysis, the odds ratio for alcohol dependence in the NN genotype of the ALDH_2 gene and AG or GG genotypes of the N glycosylation site on the ASA gene were 130.312(95% confidence interval, 17.22-986.43) and 2.344(95% confidence interval. 1.128-4.871), respectively. Conclusion : The result reiterates the association of the ALDH_2 gene polyporphism and the alcohol dependence. Logistic regression analysis additionally suggested that the N-glycosylation site on the ASA gene was associated with alcohol dependence.

韓國人에서 VNTR D1S80 遺傳座位의 遺傳的 多樣性 및 集團의 均質性 檢定

明賢君,黃迪駿,洪鎔杓,金致弘 大韓法醫學會 1994 대한법의학회지 Vol.18 No.1

Human genomic DNA prepared from whole blood sample was analyzed to estimate allelic frequencies and genetic diversity at a hypervariable variable number of tandem repeats(VNTR) D1S80 locus in 127 Korean. Target DNA fragments were amplified by polymerase chain reaction(PCR) and separated by polyacrylamide gel electrophoresis. Then, the following results were obtained. 1. A total of 23 alleles were identified at this locus, which is the biggest number of alleles observed at this locus so far(cf. 16 from U. S. Caucasians and 15 from Finnish). 2. Sixty-two genotypes, included 3 homozygotes and 59 heterozygotes, out of a total of 276 probable genotypes were also observed, which might be resulted from the small sample size compared to the number of alleles observed in this study. 3. General pattern of allelic distributions was concordant with those observed in previous studies from Finnish and U. S. Causccasians where two alleles, M18 and M23, were observed most frequently and the rest of them were observed rare(<10%) with the exception of M30 allele(14.6%) in Korean. The number of M30 allele is suspected to be increased in Korean at or after the divergence of Korean from the hypothetical ancestor probably caused by random genetic drift such as founder effect of bottleneck effect. 4. Higher level of heterozygosity was obtained in Korean(H=0.866 and H=0.881) than in Finnish(H=0.77 and H=0.79) and U. S. Cauccasians(H=0.808 and H=0.797). 5. Population homogeneity was tested to corroborate the obtained population genetic parameters calculated based on the assumption of Hardy-Weinberg equilibrium, which could be done by Chi-square test between the observed number of alleles and the expected number of alleles, because of the small sample size analyzed in this study which resulted in high proportion of undetected genotypes (78.5%) and several genotypes significantly deviated from hardy-Weinberg expectation in a sample population. The result suggests that samples were drawn from geneticically homogeneous population. 6. This study suggests that Korean is more diversified than Finnish and U. S. Cauccasians on the basis of the number of alleles and the level of heterozygosity, although Korean is known to be entirely composed of single race. Though we need more informations from other Asian countries, this result suggests frequent gene flow from neighbor countries, which is also expected based on the old Korean history of frequent invasions from Japan and China. 7. Based on the Hardy-Weinberg expectation, 216 out of 253 genotypes at D1S80 locus can be shared by less than 5 individuals among 1,000 unrelated individuals by chance. Our results suggest that the analysis of VNTR D1S80 locus can provide powerful, but imperfect by itself, DNA markers for forensic study, which can be corroborated by analyzing additional VNTR loci.

CdS 박막의 열처리효과에 관한 연구

홍성락,최치규,현동걸 제주대학교 1984 논문집 Vol.17 No.-

The annealing effects of CdS thin films prepared by the chemical vapor deposition method have been investigated. At 380℃, the annealing of CdS thin films for 30 minutes in H_(2) gas and vacuum (10^(-5) torr) has led to enhance the electrical conductivity and crystal structure of them. The resistivities are increased by as much as two and concentrations of the CdS thin films annealed have very fluctuating values, this may be expected to attniute to the surface scattering and surface potential resulted from the defects.

Electromechanical Drive System의 依한 Mo¨ssbauer Spectrum

洪致裕 東國大學校 1976 論文集 Vol.15 No.-

We got Mo¨ssbauer spectra of natural iron and stainless steel by means of a constant acceleration Mo¨ssbauer spectrometer using Electromechanical Drive System. We used stainless steel and natural iron foil as Absorbers. 14.4 kev gamma ray from a Co^57 source modulated by Doppler effect, was detected by a scintillation counter. We obtained a six-line magnetic hyperfine spectrum of natural iron, which was analyzed to express 3.324×10^5 gauss as the magnetic hyperfine field at room temperature. Zero channel was analyzed to express 49.5 channel as the velocity per channel. A single line spectrum of stainless steel absorber was also obtained to express the isomer shift of 0.43/sec

문헌에 기록된 裝類의 분석적 고찰

채홍자,이효지 漢陽大學校 韓國生活科學硏究所 1990 韓國 生活 科學 硏究 Vol.- No.9

Soy bean Sauce has been basic seasoning in our traditional food life of our nation and one of the commonly used grain cereals as a side fond stuff from ancient times. In this treatise, the kinds of soy bean sauce, the frequency of them, the measuring units, the cooking utensils, and the measuring terms, the good day or bad day to make soy bean sauce, how to make soy bean sauce without inducing maggot, how to choose water when making soy bean sauce, how to preserve soy bean sauce without losing taste and how to preserve and choose earthernware pots, and lastly how to choose salt to go with making soy bean sauce were studied from the books published from 1018 to 1984 in Korea. 1) The kinds of soy were soybean paste, soy bean sauce, red pepper paste, fermented soybeans, jip -jang, usage of materials and fish meat soy. 2) There were 141 kinds of soy, including 23 kinds of soybean paste, 27 kinds of soybean sauce, 24 kinds of red pepper paste, 15 kinds of fermented soybeans, 15 kinds of juice soy, 23 kinds of usuable materials and 14 kinds of fish meat soy. 3) There were 54 kinds of measuring units used to make the kinds of soy, 22 kinds of ca pacity(volume) unit, 3 kinds of weight unit, 15 kinds of quantity units, 5 kinds of length and thickness, and 9 kinds of the others. 4) There were 111 kinds of cooking utensils, among them earthernware pots were used in the largest quantity. There were also as many as 36 kinds of seasoning utensils used for making fermented soybeans. 5) There were 266 kinds of cooking utensils 119 kinds for preparing process, 30 kinds for mixing process, 27 kinds for heating process, 20 kinds for making process, 51 kinds for making good -looking process, 18 kinds for cutting process and one more. 6) In this dissertation were classified and arranged the good day for making soy, bad day for making soy, the way of making soy without maggot, selecting water when making soy, the way of preserving taste, the way to be avoided for making soy, the way to preserve earthernware pots for soy, the way of choosing earthernware pots, salt to be used for making soy.

Mossbauer Spectroscopy에 의한 제주화산암의 구조적 연구(Ⅰ)

洪性樂,崔致圭 제주대학교 1988 논문집 Vol.27 No.-

In this study, the Mossbauer parameters such as isomer shift and quadrupole splitting for powder samples of lava taken from three islands located in the southern part of Seoguipo are measured at the room temperature. The analysis of Mossbauer spectra shows the major iron compunds of Cheju volcanic rock are composed of olivine, pyroxene and ilmenite. In addition, the spectra have a six line magnetically hyperfine split pattern characteristic of impure hematite.

10MgO-10Fe_2O_3-30Na_2O-5OSiO_2 유리의 Mo¨ssbauer 효과 연구

홍치유,박관호,백승도,문찬호,조수열 동국대학교 1987 論文集 Vol.26 No.-

The Mo¨ssbauer effect studies of the quenched glass and heat-treated glasses were performed. The Debye and Einstien temperatures of the quenched glass, determined using the center shift and kinetic temperature, are 540K and 430K respectively. The X-ray diffraction pattern showed that the heat-treated glasses were crystallized. Form the isomer shift of the heat-treated glasses, it was concluded that the Fe^(3+) ion is predominantly octahedrally coordinated.

Mo¨ssbauer 분광법을 이용한 10MnO_2-10Fe_2O_3-30Na_2O-50SiO_2 유리내의 Fe^3+ 이온에 관한 연구

洪致裕,朴冠鎬,白承道,洪性樂 동국대학교 1986 論文集 Vol.25 No.-

We have studied the Mo¨ssbauer parameters for Fe^(3+) ion in the quenched glass and heat treated glass and heat treated glasses. The Mo¨ssbauer spectra of the quenched glass were investigated at various temperatures from 60K to 300K. Using the center shift and kinetic temperature, the Debye and einstein temperatures were calculated. The quenched glass was heat-treated at various temperatures from 530℃ to 710℃ for five hours. Both the isomer shit and quadrupole splitting parameters decreased near 590℃. And regardless of heat treatment, the Fe^(3+) ion was predominantly octahedrally coordinated.

Mo¨ssbauer 분광법에 의한 Mg-Cd 페라이트계의 자기적 성질 연구

홍치유,최달하,문용식,백승도 東國大學校 1988 論文集 Vol.27 No.-

In this study, the magnetic properties of Mg_(1-X)Cd_(X)Fe₂O₄ ferrite system has been studied by Mo‥ssbauer spectroscopy. All the samples, prepared by a ceramic sintering method, were found to be single phase spinel by X-ray diffractometry. The Mo‥ssbauer spectra. for x<=0.3, show two magnetic hyperfine splittings. one due to Fe^3+ octahedral site ions and the other due to tetrahedral site ions. While for x=0.4 spectrum shows relaxation behaviour and for x>=0.5 it exhibits quadrupole splittings. This result implicates that the magnetic properties of Mg_(1-X)Cd_(X)Fe₂O₄ferrite system change from ferrimagnetics to paramagnetics as increasing x, And the x, Cd content, dependence of Mo‥ssbauer parameters (isomer shift, quadrupole splitting, magnetic hyperfine field and line width) were investigated.