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박치영,모성환,문철호,곽재정,김태종,전용준,박유환,정춘해 朝鮮大學校 附設 醫學硏究所 1995 The Medical Journal of Chosun University Vol.20 No.2
von Willebrand's disease (vWD) is the most common autosomal-dominant inherited disorder resulting from a quantitative or a qualitative defect of von Willebrand factor (vWF). The most diagnostic pattern is the combination of a prolonged bleeding time, a reduction in plasma vWF concentration, a parallel reduction in ristocetin cofactor activity, and reduced factor Ⅷ activity, In this case, ristocetin-induced platelet aggregation data were compatible with that of vWD. Bleeding times were prolonged over 4 minutes, vWF antigen levels were 45%. vWF ristocetin cofactor activities were 0~1% and factor Ⅷ levels were 31%, when compared to the normal control. We report the case of a family with vWD. characterized by a quantitative defect in vWF
기장도,박치영,류보열,김태종,모성환,곽재정,문철호,박근홍,박유환,정춘해 朝鮮大學校 附設 醫學硏究所 1996 The Medical Journal of Chosun University Vol.21 No.1
Chronic neutrophilic leukemia is a very rare myeloproliferative disorder which is characterized by severe sustained mature neutrophilic leukocytosis in peripheral blood (PB), hepatosplenomegaly, elevated leukocyte alkaline phosphatase, serum uric acid. serun viatmin B 12 and the bleeding tendency despite normal platelet count and coagulation time, absence of philadelphia chromosome, and the absence of fever or underlying infection or disease sufficient to mimic a leukemoid reaction. We have experienced a 34-years-old male patient with atypical chronic neutrophilic leukemia. On admission, the leukocyte count was 56,860/uL. severe neutrophic leukocytosis with 76% neutrophils and rare immature forms on PB smear. Many neutrophils had toxic granules, and vacuoloes. Leukocyte alkaline phosphatase score was decreased. The cytogenetic study showed Philadelphia chromosome negative with normal karyotype.
Kwak, Cheol Hwan,Kang, Sung-Min,Jung, Euiyoung,Haldorai, Yuvaraj,Han, Young-Kyu,Kim, Woo-Sik,Yu, Taekyung,Huh, Yun Suk THE KOREAN SOCIETY OF INDUSTRIAL AND ENGINEERING 2018 JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY -S Vol.63 No.-
<P><B>Abstract</B></P> <P>A customized droplet-based microfluidic reactor was fabricated for the synthesis of silver nanoparticles (Ag NPs) using silver nitrate (AgNO<SUB>3</SUB>) and branched polyethyleneimine (BPEI) as a precursor and a reducing agent, respectively. The effects of static mixing, temperature, and the volumetric flow rates of AgNO<SUB>3</SUB> and BPEI on the particle size were investigated. The use of a static mixer and the optimization of the reaction temperature enhanced the monodispersity of the Ag NPs. In addition, the size of the Ag NPs was manipulated by changing the flow rate ratio of AgNO<SUB>3</SUB> to BPEI at 60°C for 60min.</P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
Droplet-Based Microfluidic Reactor for Synthesis of Size-Controlled CdSe Quantum Dots
Kwak, Cheol Hwan,Park, Joong Pill,Lee, Sung Sil,Muruganantham, Rethinasabapathy,Kwon, Soonjo,Roh, Changhyun,Kim, Sang-Wook,Huh, Yun Suk American Scientific Publishers 2018 Journal of nanoscience and nanotechnology Vol.18 No.2
<P>CdSe quantum dots (QDs) with a uniform size distribution were synthesized using a droplet-based microfluidic reactor. The droplet-based microfluidic reactor enabled continuous production of CdSe QDs at a temperature of less than 250 degrees C in an extremely shorter reaction time (less than 30 s) when compared with the batch reactor. The photoluminescence (PL) and ultraviolet (UV) absorption spectra of the CdSe QDs were recorded at different reaction times and the size and optical properties of the QDs were discussed. The structure morphology and elemental composition of the CdSe QDs were determined using a transmission electron microscopy (TEM) and electron-dispersive spectroscopy (EDS). The size of CdSe QDs prepared using the microfluidic reactor was estimated to be from 1.6 to 2.6 nm with an average size of 2.2 nm. This droplet-based microfluidic reactor has the potential to be automated system continuous synthesis of CdSe QDs.</P>
Kwak Cheol Hwan,서상완,김민일,허윤석,임지선 한국탄소학회 2021 Carbon Letters Vol.31 No.5
Pyrolysis fuel oil (PFO) is used for the manufacturing of high-purity pitch for carbon precursor due to its high carbon content, high aromaticity, and low heterogeneous element and impurity content. Pitch is commonly classifed with its softening point, which is most considerable physical property afecting to various characteristics of the carbon materials based on pitch, such as electrical and thermal conductivity, mechanical strength, and pore property. Hence, the softening point should be controlled to apply pitch to produce various carbon materials for diferent applications. Previous studies introduce reforming process under high pressure and two step heat treatment for the synthesis of pitch with high softening point from PFO. These methods lead to a high process cost; therefore, it is necessary to develop a process to synthesize the pitch with high softening point by using energy efective process at a low temperature. In this study, waste polyethylene terephthalate (PET) was added to control the softening point of PFO-based pitch. The pitch synthesized by the heat treatment with the addition of PET showed the softening point higher than that of the pitch synthesized with only PFO. The softening point of PFObased pitch synthesized at 420 °C was 138.3 °C, while that of the pitch synthesized by adding PET under the same process conditions was 342.8 °C. It is proposed that the efect of the PET addition on the increase in the softening point was due to the radicals generated from thermal degradation of PET. The radicals from PET react with the PFO molecules to promote the polymerization and fnally increase the molecular weight and softening point of the pitch. In addition, activated carbon was prepared by using the pitch synthesized by adding PET, and the results showed that the specifc surface area of the activated carbon increased by the addition of PET. It is expected that the pitch synthesis method with PET addition signifcantly contributes to the manufacture of pitch and activated carbon.