배혈에 따른 저빈도 전침자극이 류마토이드 관절염 유발 흰쥐의 PAG와 해마부위에서 NOS 발현에 미치는 영향

황희상,김이화,노정두,이은용 대한침구의학회 2008 대한침구의학회지 Vol.25 No.4

Objectives : This study was to investigate the effect of low frequency electroacupuncture according to acupoints combination on NOS positive neurons in the PAG and Hippocampus of Rat with adjuvant induced Rheumatoid arthritis. Methods : Arthritis was induced by intradermal injection of FCA into base of tail. Experimental group were divided into 6 group ; Normal, Control, ST36, SP9, ST36+SP9, and NA. Normal group was injected with normal saline and not treated electroacupuncture. Control group was injected with FCA and not treated electroacupuncture. ST36 group was injected with FCA and treated by 2 Hz electroacupuncture at ST36. SP9 group was injected with FCA and treated by 2 Hz electroacupuncture at SP9. ST36+SP9 group was injected with FCA and treated by 2 Hz electroacupuncture at ST36+SP9. NA group was injected with FCA and treated by 2 Hz electroacupuncture at non acupoint. Each groups were evaluated by the number of NOS-positive neurons in PAG and hippocampus by using an image analyzer and a microscope. Results : 1. The number of NOS-positive neurons of the NA group were significantly decreased in the CA2-3. 2. The number of NOS-positive neurons of the ST36 group were significantly decreased in the PAG and CA2-3. 3. The number of NOS-positive neurons of the SP9 group were significantly decreased in the PAG and DG. 4. The number of NOS-positive neurons of the ST36+SP9 group were significantly decreased in the PAG, CA1 and DG. Conclusions : It is expected that low frequency electroacupuncture can be used a treatment of rheumatoid arthritic pain and that treatment of electroacupuncture at combined acupoints is more efficient than treatment of low frequency electroacupuncture at one acupoint.

부동산경매에서 유치권 제도 개선에 관한 연구 - 절차법을 중심으로 -

황희상,박창수,Hwang, Hee-Sang,Park, Chang-Soo 한국전자통신학회 2011 한국전자통신학회 논문지 Vol.6 No.5

본 연구는 부동산 경매에서 유치권 제도의 문제점을 파악하고 이를 바탕으로 절차법적측면을 중심으로 개선방안을 제시하고자 하였다. 부동산경매에서 유치권의 문제점을 해결하기 위해서는 집행법원은 부동산의 점유관계에 있어서 일정한 기준을 정할 필요성이 있고, 유치권의 성립여부를 판단하여 첫 매각기일에 공시하는 것이 타당하다. 또한 부동산 경매절차에서 유치권 권리신고를 의무화하는 제도적 개선이 요구되며, 유치권에 대한 현황조사를 강화하고, 매각물건명세서에 유치권에 관한 사항을 포함하여 보다 공신력을 부여해야 할 필요성이 있다. 더불어 허위 및 과장 유치권자에 대해서는 법적 처벌을 보다 강화하여 부동산경매절차에 있어서 유치권의 법적 안정성을 도모 할 필요가 있다. This study was intended to identify the problem of the lien in relation to the real estate auction and present its improvements in terms of procedural laws. To resolve the problem of the lien in the real estate auction, it is valid that the Vollstreckungsgericht needs to set the certain standard in relation to the possession of real estate and notify it at the first date of sale by judging whether the lien can be established. And the institutional improvement is required to obligate one to report the lien in the procedures of the real estate auction and reinforce the survey of the present condition of the lien. And it is necessary to impose the more public confidence on the statement of sale by including the matter of the lien in it. In addition, it is necessary to reinforce legal punishment to the false and fictitious lienholder and establish the legal stability of the lien in the process of the real estate auction.

마미 증후군 FBSS 증례보고

황희상,전재천,차정호,정기훈,이참결,노정두,이은용 대한침구의학회 2009 대한침구의학회지 Vol.26 No.1

Objectives : The purpose of this study was to evaluate the oriental conservative treatment for FBSS patient who were diagnosed as the Cauda equina syndrome. Methods : The patient were treated by the oriental medical conservative treatment including herbal medication, dry needle acupuncture, direct moxibustion and indirect moxibustion, cupping therapy and, physical therapy. We estimated by Visual Analog Scale and Oswestry disability index for evaluate the effect of Oriental conservative treatment. Results : After treatment, patient’s visual analogue scale score and Oswestry disability index score were generally decreased. Conclusions : The oriental medical conservative treatment might be an effective method to treat the FBSS patient who were diagnosed as the Cauda equina syndrome.

Intestinal Diffuse Large B-Cell Lymphoma: An Evaluation of Different Staging Systems

황희상,윤덕현,서철원,박찬식,허주령 대한의학회 2014 Journal of Korean medical science Vol.29 No.1

The gastrointestinal tract is the most common primary extranodal site for diffuse large B-cell lymphoma (DLBCL). However, there is no consensus on the most appropriate staging system for intestinal DLBCL. We evaluated the utility of the modified Ann Arbor system, the Lugano system, and the Paris staging system (a modification of the Tumor, Node, Metastases [TNM] staging for epithelial tumors) in 66 cases of resected intestinal DLBCL. The cases were treated with surgery, plus either cyclophosphamide, doxorubicin, vincristine, and prednisolone (CHOP) chemotherapy alone (n=26) or with the addition of rituximab immunotherapy (n=40). Median follow-up time was 40.4 months (range, 2.1-171.6 months). Fifty-six patients (84.8%) achieved complete remission. The overall 5-yr survival rate was 86.4% (57/66). Of the stage categories defined for each staging system, only the T stage of the Paris classification showed prognostic significance for overall survival by univariate analysis. However, none of the stage parameters was significantly correlated with patient survival on multivariate analysis. In conclusion, the results suggest that the T stage of the Paris classification system may be a prognostic indicator in intestinal DLBCL. The results also imply that in surgically resected intestinal DLBCL, the addition of rituximab to the CHOP regimen does not confer significant survival advantage.

Prognostic Impact of Age at the Time of Diagnosis in Korean Patients with Diffuse Large B-cell Lymphoma in the Rituximab Era: A Single Institution Study

황희상,김미정,박찬식,윤덕현,서철원,허주령,고현정 대한암학회 2021 Cancer Research and Treatment Vol.53 No.1

Purpose In contrast to the Western diffuse large B-cell lymphoma (DLBCL), prognostic impact of age in a Korean population with DLBCL has not been fully evaluated. Materials and Methods Six hundred and eight DLBCL patients treated with rituximab-containing chemotherapeutic regimens from January 2002 to March 2012 in Asan Medical Center were enrolled. Survival models using the restricted cubic spine−transformed age variable were constructed to evaluate non-linear relationships between age and survival outcome. Finally, age was categorized according to the conventional international prognostic index (IPI), National Comprehensive Cancer Network (NCCN)-IPI, and Grupo Español de Linfomas/Trasplante Autólogo de Médula Ósea (GELTAMO)-IPI schemes and the prognostic implications were evaluated. Results The relative hazard did not change significantly during the first to fifth decades, but began to increase exponentially in patients aged over 62 years. This pattern or relationship was also retained in a multivariate model fitted to the age-adjusted IPI and relative dose intensity. Multivariate survival analysis revealed that age > 75 years, but not age > 60 years, was associated independently with poor overall and progression-free survival when the relative dose intensity and age-adjusted IPI were taken into account. Conclusion The outcome of DLBCL in Korean populations may deteriorate rapidly as age exceeds 62 years. Therefore, a consensus cutoff value for age in Korean DLBCL patients should be determined to better predict prognosis.

Vascular Ehlers-Danlos syndrome with distinct histopathologic features

황희상,송진우,장세진 대한병리학회 2022 Journal of Pathology and Translational Medicine Vol.56 No.3

Prognostic value of immunohistochemical algorithms in gastrointestinal diffuse large B-cell lymphoma

황희상,윤덕현,서철원,박찬식,허주령 대한혈액학회 2013 Blood Research Vol.48 No.4

BackgroundDiffuse large B-cell lymphoma (DLBCL) is a heterogeneous clinicopathological entity, and its molecular classification into germinal center B cell-like (GCB) and activated B cell-like (ABC) subtypes using gene expression profile analysis has been shown to have prognostic significance. Recent attempts have been made to find an association between im-munohistochemical findings and molecular subgroup, although the clinical utility of im-munohistochemical classification remains uncertain. Methods The clinicopathological features and follow-up data of 68 cases of surgically resected gas-trointestinal DLBCL were analyzed. Using the immunohistochemical findings on tissue microarray, the cases were categorized into GCB and non-GCB subtypes according to the algorithms proposed by Hans, Muris, Choi, and Tally. ResultsThe median patient age was 56 years (range, 26‒77 years). Of the 68 cases included, 39.7% (27/68) involved the stomach, and 60.3% (41/68) involved the intestines. The GCB and non-GCB groups sorted according to Hans, Choi, and Tally algorithms, but not the Muris algorithm, were closely concordant (Hans vs. Choi, κ=0.775, P<0.001; Hans vs. Tally, κ=0.724, P<0.001; Choi vs. Tally, κ=0.528, P<0.001). However, there was no prog-nostic difference between the GCB and non-GCB subtypes, regardless of the algorithm used. On univariate survival analyses, international prognostic index risk group and depth of tumor invasion both had prognostic significance.ConclusionThe Hans, Choi, and Tally algorithms might represent identical DLBCL subgroups, but this grouping did not correlate with prognosis. Further studies may delineate the associa-tion between immunohistochemical subgroups and prognosis.

교통사고 환자 77례에 대한 임상적 고찰

황희상,정기훈,전재천,박재연,김민석,이태호,노정두,이은용,Hwang, Hee-Sang,Park, Jae-Yeon,Kim, Min-Seok,Jeon, Jae-Cheon,Jung, Ki-Hoon,Lee, Tae-Ho,Roh, Jeong-Du,Lee, Eun-Yong 척추신경추나의학회 2009 척추신경추나의학회지 Vol.4 No.2

Objectives : The purpose of this study was to find out tendency of traffic accident patients treated in korean medicine hospital. Methods : We investigated 77 patients who were treated in Semyung University Korean Medicine Hospital from 1 st, January, 2007 to the 30st September, 2009. Results and Conclusions : 1. In distribution of gender and age, the rate of male was 36.4%, that of female was 63.6% and majority of patients were twenties, thirties and forties. 2. In the traffic accident patterns, the most was car crash from behind(49.4%) and after traffic accident, 42 patients(54.6%) visited our hospital in less than 5 days. 3. 22 patients(28.6%) choose the oriental medical treatment for primary care. And 35 patients(45.4%) visited our hospital due to preference of oriental medicine. 4. In partial pain, most was the neck(76.6%), followed by low back(61.0%). 5. In radiation test(excluded sprain and straightening), the most was HIVD of L-SPINE(14.0%). 6. In the periods of admission, less than 7 days was the 1st(36.4%), 14 days was the 2nd(27.3%). 7. The treatment was effective to 67 patients out of 77 patients who had been hospitalized.

항만 근로자의 해상 추락사고에 대응하는 해상 구조 로봇

황희상 ( Hee-sang Hwang ),강민철 ( Min-cheol Kang ),정욱현 ( Wook-hyun Jung ),정진원 ( Jin-won Jung ),김인수 ( In-soo Kim ) 한국정보처리학회 2023 한국정보처리학회 학술대회논문집 Vol.30 No.2

해상 추락사고에 대응하는 해상 구조 로봇 프로젝트는 항만 근로자의 추락사고 감지와 피해자 구조에 초점을 둔다. 센서와 자율주행 기술을 접목하여 정확하고 효율적인 구조 작업을 가능케 하고, 자체 개발한 워터센서를 활용하여 신속한 구조를 지원한다. YOLO를 이용한 피해자 위치 파악, 블루투스 기반 관리자 어플리케이션, 해상 추락 감지 및 센서를 탑재한 구명 조끼, 자동 구조 작업 등의 기능을 통합하여 항만 근로자의 안전을 보장하며, 해수욕장 등 다양한 환경에서도 확장 가능한 창의적인 기술을 제시한다.

유치권 제도 개선을 통한 부동산경매 활성화에 관한 연구

황희상(Hee sang Hwang) 한국전자통신학회 2011 한국전자통신학회 학회지 Vol.5 No.1

본 연구는 부동산 경매에서 유치권 제도의 문제점을 파악하고 이를 바탕으로 유치권 제도 개선방안을 제시하고자 하였다. 부동산경매에서 유치권의 문제점 을 해결하기 위해서는 집행법원은 부동산의 점유관계에 있어서 일정한 기준을 정할 필요성이 있고, 유치권의 성립여부를 판단하여 첫 매각기일에 공시하는 것이 타당하다. 또한 부동산 경매절차에서 유치권 권리신고를 의무화하는 제도적 개선이 요구되며, 유치권에 대한 현황조사를 강화하고, 매각물건명세서에 유치권에 관한 사항을 포함하여 보다 공신력을 부여해야 할 필요성이 있다. 더불어 허위 및 과장유치권자에 대해서는 법적 처벌을 보다 강화하여 부동산경매 절차에 있어서 유치권의 법적 안정성을 도모 할 필요가 있다. This study was intended to identify the problem of the lien in relation to the real estate auction and present its improvements in tenns of procedural laws. To resolve the problem of the lien in the real estate auction, it is valid that the Vollstreckungsgericht needs to set the certain standard in relation to the possession of real estate and notify it at the first date of sale by judging whether the lien can be established. And the institutional improvement is required to obligate one to report the lien in the procedures of the real estate auction and reinforce the survey of the present condition of the lien. And it is necessary to impose the more public confidence on the statement of sale by including the matter of the lien in it. In addition, it is necessary to reinforce legal punishment to the false and fictitious lienholder and establish the legal stability of the lien in the process of the real estate auction.