영양관리와 운동이 중년 비만여성의 혈중 호모시스테인 수준과 항산화 영양소 섭취에 미치는 영향

한정순,김애정,Han, Jung-Soon,Kim, Ae-Jung 한국식품영양학회 2014 韓國食品營養學會誌 Vol.27 No.3

The purpose of this study was to investigate the association of homocysteine and antioxidant nutrients with obesity in Korean middle aged women. The study subjects included were middle-aged obese women (n=36) whose body mass index (BMI) was greater than $25kg/m^2$. A total of 36 participants were randomly divided into two groups. They were assigned to either the Nutritional Management and Exercise (NME) program or the Exercise Management (EM) program, which were both conducted for 3 months. We measured serum homocysteine, total cholesterol and HDL cholesterol levels of the participant. We also measured the dietary intakes of antioxidant nutrient, cholesterol, body weight, body mass index, blood pressure, and $VO_2$. At the end of both programs, please confirm this change. It was unclear when these measurements were shown to have decreased. The body weight and BMI of NME group were decreased compared to those of EM group. The serum total cholesterol levels of the participants in NME group were significantly decreased, in contrast to EM group. Also, serum homocysteine levels of NME group participants were decreased compared to EM group, but the difference was not statistically significant. In the NME group, there were significant differences in the change of dietary cholesterol and vitamin C intake. These results showed that participating NME program will continuously promote the healthy status of the middle aged obese women, compared to participating only in the EM program.

The Effects of Auricularia auricula-judae on Blood Lipids Profile and Bone Density of Middle Aged Abdominal Obese Women

한정순,김재근,김애정,Han, Jung-Soon,Kim, Jae-Kun,Kim, Ae-Jung The Korean Society of Food and Nutrition 2012 韓國食品營養學會誌 Vol.25 No.4

본 연구는 안전하면서 효율적으로 비만을 개선시키는데 도움이 될 수 있는 식품소재로 목이버섯을 선정하여 복부 비만이 있는 중년 여성의 골밀도 및 혈청지질농도에 미치는 영향에 대하여 알아보고자 하였다. 30~50대의 복부비만 여성 30명에게 4주 동안 대조군은 목이버섯을 섭취시키지 않았고, 실험군은 목이버섯을 식사와 함께 섭취하도록 하였다. 실험 전 후 골밀도(T-score, Z-score), 총 콜레스테롤, HDL-콜레스테롤, LDL-콜레스테롤, 중성지방을 측정하였다. 연구결과, 목이버섯 섭취군과 대조군 간에 T-score와 Z-score는 유의한 차이를 보이지 않았지만, 목이버섯 섭취군의 혈청 총 콜레스테롤, LDL-콜레스테롤 및 중성지방 수준이 대조군에 비해 유의하게 감소되었다.

고지방식이와 식이섬유가 흰쥐의 체내 지질대사에 미치는 영향

한정순(Jung-Soon Han),한용봉(Yong-Bon Han) 한국식품영양과학회 1994 한국식품영양과학회지 Vol.23 No.4

이유기를 지난 웅성흰쥐를 대조식이 (C), 고지방식이 (HF) 및 고지방 고에너지식이 (HFHE)로 4주간 사양하고 일부를 희생시킨 후, HF군과 HFHE군 일부에 식이섬유 pectin과 cellulose를 각 각 첨가한 HF-P, HF-C, HFHE-P, HFHE-C 식이를 C, HF, HFHE 식이와 함께 4주간 더 사양한 후 희생시켜 체중증가량, 총 에너지섭취량, 총 식이섭취량, 식이효율, 간장과 비장의 무게, 혈중 지질의 성상 및 간세포에 미치는 영향을 비교 관찰한 결과 체중증가는 C군, HF군, HFHE군간의 유의적 차이는 없었으며, 식이섬유 첨가시 모두 체중이 감소되었다. 총 에너지 섭취량은 C군이 가장 많았고, 식이효율은 HFHE군이 가장 높았으며, 식이섬유 첨가에 의해서는 영향을 받지 않았다. 간장의 무게는 C군, HF군, HFHE군 모두 식이의 영향이 없었고, pectin과 cellulose 첨가에 의한 변화도 나타내지 않았다. 비장의 무게는 C군보다 HF군과 HFHE군이 감소하였으나, pectin 과 cellulose 첨가에 의해서는 변화가 없었다. 혈중 총 지질, 총 콜레스테롤, 중성지방 및 언지질의 함량은 각 실험군 모두 실험기간이 경과함에 따라 증가되었으며, 특히 HFHE군이 유의성 있게 증가하였고 pectin과 cellulose를 첨가 하였을 때는 감소하였으며 pectin이 cellulose 보다 감소 효과가 있었다. The effect of diets (high fat, high fat high energy, pectin, cellulose) on lipid metabolism were investigated in 70 male rats for 8 weeks. The rats were assigned to either a control (C), high fat (HF) or high fat high energy(HFHE) group for 4 wks. During the next 4wks, reassigned to one of three treatments (high fat, pectin, cellulose) in the HF group and one of three treatment (hign fat high energy, pectin, cellulose) in the HFHE group. Therefore, the total treatment group became 7 (C, HF, HF-P, HF-C, HFHE, HFHE-P, HFHE-C). Parameters evaluated and compared for each diet were body weight, total energy intake, Feed Efficiency Ratio (F.E.R), total lipid, total cholesterol (TC), HDL-cholesterol(HDL-C), HDL-C/TC, triglyceride (TG), phospholipid in serum, and changes in liver and spleen. The results are summarized as follows; 1. There were no significant differences in body weight gain among the groups. 2. Total energy intake was higher in the C group than other groups. Feed Efficiency Ratio (F.E.R) was higher in the HFHE group than other groups. 3. There was no significant difference in the weight gain of liver (100g/B.W.) among the groups. However, the weight gain of spleen (100g/B.W.) was higher in the C group than other groups (HF and HFHE). 4. Total lipid, TC, TG, and phospholipid increased significantly in all groups for the first 4 wks. However, after 8 wks, pectin and cellulose supplementation groups decreased significantly. Therefore, we can conclude that the HF and the HFHE diet led to increase lipids concentration and the pectin and the cellulose treatments decreased lipids concentration in serum. However, the pectin treatment had greater effect than the cellulose treatment.

고지방식이 및 식이섬유가 흰쥐의 정소상체 지방조직의 지방세포에 미치는 영향

한정순(Han Jung Soon),한용봉(Han Yong Bong) 韓國營養學會 1994 Journal of Nutrition and Health Vol.27 No.2

흡연남자들의 항산화제섭취에 금연교육이 미치는 영향

한정순 ( Jung Soon Han ),김철환 ( Cheol Hwan Kim ) 한국미용학회 2009 한국미용학회지 Vol.15 No.2

This study was performed to investigate the pattern of diet, antioxidants, the dietary behaviors, plasma lipid profile, body weight, and body mass index(BMI) etc, by smoking cessation program. The subjects, smokers were participated in smoking cessation program, who agreed to blood sampling and also examined body weight, body mass index(BMI), food intakes, and dietary habits. The result obtained were as follows: The intake of antioxidant nutrient-Vitamin A, C, and beta-carotene were lower for smoking cessation failure group than for smoking cessation group. Serum TG(Triglyceride) level of smoking cessation group was not changed, but that of smoking cessation failure group was increased. Blood glucose level of smoking cessation group was decrease, and that of smoking cessation failure group was not changed.

비만관리교육프로그램(영양교육과 운동프로그램)이 비만아동에 미치는 영향

한정순 ( Jung Soon Han ),이은희 ( Eun Hee Lee ) 한국미용학회 2008 한국미용학회지 Vol.14 No.4

This study was performed to investigate the effect of Obesity Management Eduction Program (Nutritional Education and Physical Activity Program) for the obesity children. We measured the dietary behaviors, serum lipid profile, body weight, body mass index(BMI), and physical activity strength etc, by Obesity Management Eduction Program. The subjects of this study were total overweight and obesity 39 students of elementary school in Seoul. They had received Obesity Management Eduction Programs three months. This program included regular nutritional education, and 3 times per week of physical activity program. The result obtained were as follows: There were decreased in body fat, serum cholesterol, especially LDL(Low Density Lipoprotein)-Cholesterol significantly after 3 months Nutritional Education and Physical Activity Program. These results show that continuous Obesity Management Eduction Program will promote the health of obesity children. Therefore this programs should be expanded widely among elementary school students in Korea.

비만여성의 체성분과 혈중 지질에 비만관리프로그램이 미치는 영향

한정순(Jung-Soon Han),이은희(Eun-Hee Lee) 한국생활과학회 2012 한국생활과학회 학술대회 Vol.2012 No.11

HepG2 세포주를 이식한 BALB/c Nude Mice에서 흑삼의 고형암 개선효과

강신정,한정순,김애정,Kang, Shin-Jyung,Han, Jung-Soon,Kim, Ae-Jung 한국식품영양학회 2015 韓國食品營養學會誌 Vol.28 No.2

The aim of this study was to examine the ameliorating effect of black ginseng on the growth of the HepG2 cell transplanted tumor in BALB/c nude mice. 27 male BALB/c nude mice (all six weeks old) were randomly divided into three groups: the control group, the first treatment group (HepG2300RG, using 300 mg/kg red ginseng), and the second treatment group (HepG2300BG, using 300 mg/kg black ginseng). The HepG2300BG in the HePG2 cells showed increased mean survival time than that of red ginseng group. The size and volume of the tumor in the 300BG group showed significant reduction compared to those of the HepG2300RG group (p<0.05). The body weight and liver weight of the HepG2300RG group was not significantly different with control and HepG2300BG group. The serum levels of ALT and AST in the HepG2300RG and HepG2300BG group were significantly lower than those of the control group. In conclusion, these results suggest that the black ginseng may have possible anti-tumor activities.

새로운 적외선 온열기의 열충격 단백질 유도

김태호,한정순,김재찬,Tae-Ho Kim,Jung-Soon Han,Jae-Chan Kim 대한안과학회 2005 대한안과학회지 Vol.46 No.5

Purpose: To investigate if the use of the infrared warm compression device often used in clinical settings induced heat shock proteins. Methods: Subjects were heat-treated with an infrared warm compression device for 20 minutes. We examined the temperature of the upper eyelid and cornea before and after heat treatment and images were obtained by Digital Infrared Thermal Imaging System. After 6 hours of heat treatment, conjunctival epithelial cells were obtained by gently pressing nitrocellulose paper on the conjunctival surface for 3 to 5 seconds Immunocytochemical staining analysis was performed on the obtained samples. Tear samples were obtained prior to heat treatment and Western blot was performed to observe the expression patterns of heat shock proteins 27, 47, 70, and 90. Results: By Western blot and immunocytochemical analysis, heat shock proteins 70 and 27 were significantly increased in the heat-treated samples. However, no difference was observed for heat shock proteins 47 and 90 before and after heat treatment, according to the immunocytochemical analysis. On Western blot, heat shock protein 47 was slightly increased by heat treatment but heat shock protein 90 did not show a significant difference after heat treatment. Conclusions: It was observed that the infrared warm compression device significantly increased the induction of heat shock proteins 27 and 70, and that 47 was also slightly induced. This result suggests that the device developed herein could be used as a new therapeutic modality for the reduction of inflammatory cell injury through the induction of heat shock proteins.

로스팅 서리태를 이용한 음료 제조 및 품질 평가

정수옥,김혜연,한정순,김민주,강미숙,김애정,Jeong, Soo-ok,Kim, Hae-yean,Han, Jung-soon,Kim, Min-ju,Kang, Mi-sook,Kim, Ae-Jung 한국식품영양학회 2016 韓國食品營養學會誌 Vol.29 No.4

This study was performed to develop and evaluate beverage prepared with optimally roasted seoritae to maximize the isoflavone content and antioxidant activities of the beverage. Isoflavone content was maximized at the roasting temperature of $110^{\circ}C$ for 20 min. Both DPPH radical scavenging activity and ABTS radical scavenging activity along with total polyphenol content were highest when seoritae was roasted at $110^{\circ}C$ for 20 min. Western blotting was used to determine the level of nuclear factor of activated T-cells 1(NFATc1) involved in controlling osteoclast differentiation. The results showed that NFATc1 had a concentration-dependent inhibitory effect when the RoS110 (roasted seoritae at $110^{\circ}C$ for 20 min) samples were processed at varying concentrations (10, 50, and $100{\mu}g/mL$). Tea samples were prepared from optimally roasted seoritae by varying brewing times (5~90 min) at $65^{\circ}C$, and tea brewed for 60 min had the highest preference with $65^{\circ}C$ as the preferred temperature for drinking.