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한은미,송동은,엄대운,최혜정,차희정,허주영,Han, Eun-Mee,Song, Dong-Eun,Eom, Dae-Un,Choi, Hye-Jeong,Cha, Hee-Jeong,Huh, Joor-Yung 대한세포병리학회 2006 대한세포병리학회지 Vol.17 No.2
In the investigation of superficial lymphadenopathy of unknown cause, fine needle aspiration (FNA) cytology plays an invaluable role. It enables the differentiation of benign lymphadenopathy from lymphoid and non-lymphoid malignancies, obviating the need for open biopsy, and allowing the triage of patients. Cytopathologists should be familiar with the typical FNA patterns of benign lymphadenopathy, and recognize and differentiate among categories. In a minority of cases of benign lymphadenopathy, FNA can render a specific diagnosis. Benign lymphadenopathies are generally categorized into reactive lymphoid hyperplasia (RLH), inflammatory or infectious processes, and benign lymphoproliferative disorders. RLH characteristically presents with a heterogeneous and polymorphous smear composed of normal cellular constituents of lymph nodes, in contrast with the homogeneous or monomorphic smear of most lymphomas. The caveat is that various malignant disorders may also present with polymorphous populations. It is also important to recognize thatbenign lymphoid smears may sometimes contain atypical cells that raise the suspicion of malignancy. Clinical information should always be the integral part of the diagnostic criteria in FNA of lymphadenopathy. If there is any doubt about the benign nature of the smear, it is prudent to suggest biopsy and ancillary studies.
난소의 성끈 종양을 닮은 자궁종양 -세포학적 소견 1예 보고-
김인선,한은미,정운용,이주한,염범우,Kim, In-Sun,Han, Eun-Mee,Jung, Woon-Yong,Lee, Ju-Han,Yeom, Bum-Woo The Korean Society for Cytopathology 2003 대한세포병리학회지 Vol.14 No.2
Uterine stromal tumors with features of ovarian sex-cord differentiation are relatively rare. The neoplasms composed of sex cord-like components in more than 50% of the tumor are classified as group II. We report the cytologic findings of a case of uterine tumor resembling ovarian sex-cord tumor. The cervical smears of a 62-year-old woman with submucosal tumor showed loose aggregates of spindle cells as well as glandular or tubular structures of round cells with a distinct ceil membrane and a prominent small nucleolus. Because uterine stromal tumor can have sex cord differentiation, its possibility should be considered in the interpretation of cervical smears.
HIV 음성 환자에서 형질모세포종의 세침흡인 세포소견 - 1예 보고 -
이향임,구현령,한은미,공경엽,서철원,류민희,강윤구,박찬정,허주령,Lee, Hyang-Im,Koo, Hyun-Ryung,Han, Eun-Mee,Gong, Gyung-Yub,Suh, Chul-Won,Ryu, Min-Hee,Kang, Yoon-Goo,Park, Chan-Jeong,Huh, Joo-Ryung The Korean Society for Cytopathology 2005 대한세포병리학회지 Vol.16 No.1
Plasmablastic lymphoma (PBL) is a recently described aggressive B-cell neoplasm, which usually manifests as a localized disease of the oral mucosa in individuals infected with human immunodeficiency virus (HIV). Recently we encountered a case of plasmablastic lymphoma manifesting in the left maxillary sinus and cervical lymph node of a previously healthy HIV-negative man, 48 years of age. we conducted a fine-needle aspiration smear of the cervical lymph node, and this was found to be highly cellular with numerous large cells exhibiting eccentrically positioned nuclei, prominent nucleoli, and moderate quantities of basophilic cytoplasm. A biopsy of the mass in the maxillary sinus evidenced diffuse growth of similar plasmablastic cells. These tumor cells were negative for the leukocyte common antigens, CD20, CD3, CD30, and EMA. However, the cells tested positive for CD79a and CD138/syndecan-1. The tumor cells also exhibited L-light-chain restriction. The Ki-67 proliferation index was measured at almost 100%. The patient was diagnosed with plasmablastic lymphoma. After three cycles of combination chemotherapy and radiotherapy, the patient went into complete remission, and currently remains in this state.
Uterine tumor resembling ovarian sex - cord tumor 1 예와 그 임상적 고찰
김재웅(Jae Woong Kim),한은미(Eun Mee Han) 대한산부인과학회 2002 Obstetrics & Gynecology Science Vol.45 No.2
Uterine tumor resembling ovarian sex-cord tumor (UTROSCT) were first described by Clemen and Scully in 1976. They are a heterogenous group of uterine neoplasm characterised by pure or predominant histological patterns that resembled sex cord tumors of ovary. Clemen and Scully divide the tumors into two groups according to sex-cord-like structures within tumors (the so-called group I tumors with 50% of sex-cord elements, the so-called group II tumors with almost completely sex-cord-like structures). The histogensis of the sex-cord-like elements is uncertain, the group I tumor appears to be more malignant. We experienced a case of UTROSCT in a 44 years old woman underwent LAVH under tantative diagnosis of uterine myoma and report the case with brief review of literature.
송우석,최준철,김학수,한은미,Song, Woo-Suk,Choi, Joon-Cheol,Kim, Hak-Soo,Han, Eun-Mee 대한근골격종양학회 2010 대한골관절종양학회지 Vol.16 No.2
섬유골성 가종양(fibro-ossous pseudotumor)은 빠르게 성장하면서 동통을 유발하는 매우 드문 양성 병변이다. 이 병변은 악성으로 오인되기도 하지만 국소절제술만으로 치료가 되는 비침습형 질환으로, 주로 수부에 발생한다. 제 1족지 원위 지골의 종물과 동통으로 내원한 20세 여자 환자에서 발생한 섬유골성 가종양 1예를 경험하여 문헌 고찰과 함께 보고하는 바이다. Fibro-osseous pseudotumor is an extremely rare benign lesion which is fast-growing and painful. It is often misdiagnosed as a malignancy, but it is a noninvasive entity and can be cured by simple resection. We report a case of fibro-osseous pseudotumor of the distal phalanx of great toe in 20-year-old female patient who present with painful mass.
김동훈,김민경,채승완,이경분,한은미,강성희,손진희,Kim, Dong-Hoon,Kim, Min-Kyung,Chae, Seoung-Wan,Lee, Kyoung-Bun,Han, Eun Mee,Kang, Sung-Hee,Sohn, Jin-Hee The Korean Society for Cytopathology 2007 대한세포병리학회지 Vol.18 No.2
Sono-guided fine needle aspiration (FNA) of the thyroid is widely used, but the aspirated samples are typically not well preserved and low cellularity makes diagnosis difficult in many cases. The object of the current study is to evaluate the adequacy and diagnostic accuracy of the use of $SurePath^{TM}$ liquid-based cytology (SP-LBC) in the sonoguided fine needle aspiration of the thyroid nodule and to compare its use with that of the use of a conventional smear (CS). A total of 172 sono-guided FNAs of thyroid nodules from April to June, 2006 were prepared by the use of the split method with either SP-LBC or CS; the samples were stained with the use of hematoxylin-eosin (H&E) and Papanicolaou (Pap) stains. A cyto-histological correlation was performed in 69 (30 SP and 39 CS) cases that had been histologically confirmed. The rate of producing unsatisfactory slides by the use of the SP-LBC method (9.3%) was less than that of the use of the CS method (20.9%). The diagnostic accuracy of the SP method (93.3%) was better than that of the CS method (85.3%). The sensitivity and specificity of the SP method (94.4% and 92.3%) was better than that of the CS method (83.3% and 70%), respectively (p < 0.05). The CS of sono-guided aspirated specimens had some unavoidable limitations related to inadequate sampling such as a bloody background, low cellularity and an indication that some clinicians smeared many useless slides (averaging four to ten slides), and that most slides showed only blood that included few follicular cells. The SP method resulted in more thinly smeared slides and showed cleaner background and greater cellularity than the use of the CS method. Each follicular cell shows superior nuclear detail, and more distinct cytoplasmic features than with the use of the CS method. SP-LBC appears to be an easy, highly accurate, and reliable cytological method for employ for a diagnostic approach of thyroid disease and thyroid nodules. The SP-LBC method is a suitable alternative to the CS method to overcome diagnostic difficulties.
제 1 중족골에 발생한 기괴 방골성 골연골성 증식증: 증례 보고
김우성,정유훈,오상훈,한은미,Kim, Woo-Sung,Jung, Yu-Hun,Oh, Sang-Hun,Han, Eun-Mee 대한근골격종양학회 2014 대한골관절종양학회지 Vol.20 No.2
기괴 방골성 골연골성 증식증(Nora씨 병변)은 드문 발생률을 가진 양성 종양으로 주로 수부 및 족부의 단관골에서 발생하는 것으로 알려져 있으나 중족골에서 발생한 증례가 국내에서 보고된 경우는 매우 드물다. 저자들은 중족골에 발생한 기괴 방골성 골연골성 증식증을 경험하였기에 문헌고찰과 함께 보고한다. Bizarre parosteal osteochondromatous proliferation (Nora's lesion) is a rare benign tumor and known to be primarily occur in the small tubular bone of the hands and feet. However, it is very unusual to be reported that it occurs in metatarsal bone in Korea. Thus, we report this tumor of metatarsal bone including the literature review because we have experienced this example.
Meigs` 증후군과 경화복막염을 동반한 양측성 난소섬유난포막증
지용일 ( Yong Il Ji ),서미원 ( Mee Won Seo ),한은미 ( Eun Mee Han ),김대연 ( Dae Yeon Kim ),서대식 ( Dae Sil Suh ),김종혁 ( Jong Hyeok Kim ),김용만 ( Yong Man Kim ),김영탁 ( Young Tak Kim ),남주현 ( Joo Hyun Nam ) 대한산부인과학회 2006 Obstetrics & Gynecology Science Vol.49 No.7
Fibrothecoma is mesenchymal tumor deriving from the ovarian stroma composed of theca-like elements and fibrous tissues. Fibroma is rarely associated with Meigs` syndrome which consists of an ovarian fibroma, ascites, and pleural effusion. And also, sclerosing peritonitis associated with thecoma of the ovary is a rare, but intriguing phenomenon characterized by striking peritoneal reactive fibrosis. We have experienced a case of Meigs` syndrome and sclerosing peritonitis associated with fibrothecoma of the bilateral ovaries in a 57-year-old woman. We report a case with brief review of literatures.
전동옥 ( Dong Ok Jeon ),박주상 ( Ju Sang Park ),김지은 ( Ji Eun Kim ),이상진 ( Sang Jin Lee ),조효진 ( Hyo Jin Cho ),임성규 ( Sung Gyu Im ),김일동 ( Il Dong Kim ),한은미 ( Eun Mee Han ) 대한소화기학회 2013 대한소화기학회지 Vol.62 No.5
Inferior mesenteric arteriovenous fistula is rare and may be congenital or acquired. Affected patients present with abdominal pain, mass, or manifestations of portal hypertension and bowel ischemia. Until now, inferior mesenteric arteriovenous fistula due to trauma has not been reported. Herein, we report a case of a 53-year-old woman who had inferior mesenteric arteriovenous fistula considered to have originated from remote blunt trauma that was successfully treated by surgical resection of only the arteriovenous fistula without colectomy. To our knowledge, this is the first case of traumatic inferior mesenteric arteriovenous fistula. (Korean J Gastroenterol 2013;62:296-300)