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        • KCI등재

          Co-authorship patterns and networks of Korean radiation oncologists

          최진현,강진오,박서현,김상기 대한방사선종양학회 2011 Radiation Oncology Journal Vol.29 No.3

          Purpose: This research aimed to analyze the patterns of co-authorship network among the Korean radiation oncologists and to identify attributing factors for the formation of networks. Materials and Methods: A total of 1,447 articles including contents of ‘Radiation Oncology’ and ‘Therapeutic Radiology’ were searched from the KoreaMed database. The co-authorship was assorted by the author’s full name, affi liation and specialties. UCINET 6.0 was used to fi gure out the author’s network centrality and the cluster analysis, and KeyPlayer 1.44 program was used to get a result of key player index. Sociogram was analyzed with the Netdraw 2.090. The statistical comparison was performed by a t-test and ANOVA using SPSS 16.0 with p-value < 0.05 as the signifi cant value. Results: The number of articles written by a radiation oncologist as the fi rst author was 1,025 out of 1,447. The pattern of coauthorship was classifi ed into fi ve groups. For articles of which the fi rst author was a radiation oncologist, the number of singleauthor articles (type-A) was 81; single-institution articles (type-B) was 687; and multiple-author articles (type-C) was 257. For the articles which radiation oncologists participated in as a co-author, the number of single-institution articles (type-D) was 280 while multiple-institution articles (type-E) were 142. There were 8,895 authors from 1,366 co-authored articles, thus the average number of authors per article was 6.51. It was 5.73 for type-B, 6.44 for type-C, 7.90 for type-D, and 7.67 for type-E (p = 0.000) in the average number of authors per article. The number of authors for articles from the hospitals published more than 100 articles was 7.23 while form others was 5.94 (p = 0.005). Its number was 5.94 and 7.16 for the articles published before and after 2001 (p = 0.000). The articles written by a radiation oncologist as the fi rst author had 5.92 authors while others for 7.82 (p = 0.025). Its number was 5.57 and 7.71 for the Journal of the Korean Society for Therapeutic Radiology and Oncology and others (p = 0.000), respectively. Among the analysis, a signifi cant difference in the average number of author per article was indicated. The out-degree centrality of network among authors was 4.26% (2.03–7.09%) while in-degree centrality was 1.31% (0.53–2.84%). The three signifi cant nodes were classifi ed and listed as following: Choi, Eun Kyung for 1991-1995, Kim, Dae Young for 1998-2001, Park, Won and Lee, Sang Wook for 2003-2010. Choi, Eun Kyung and Kim, Dae Young appeared in two cases, and ranked as the highest degree in centrality. In the key player analysis, Choi, Eun Kyung and Lee, Sang Wook appeared in two cases, and ranked as the highest. From the cluster analysis, Sungkyunkwan University, Seoul National University and Yonsei University revealed as the three large clusters when Ulsan University, Chonnam National University, and Korea Institute of Radiological & Medical Science as the medium clusters. Conclusion: The Korean radiation oncologist’s society shows a closed network with numerous relationships among the particular clusters, and the result indicates it is different from other institutions in the pattern of co-authorship formation of the major hospitals.

        • KCI등재후보

          Basics of particle therapy II: relative biological effectiveness

          최진현,강진오 대한방사선종양학회 2012 Radiation Oncology Journal Vol.30 No.1

          In the previous review, the physical aspect of heavy particles, with a focus on the carbon beam was introduced. Particle beam therapy has many potential advantages for cancer treatment without increasing severe side effects in normal tissue, these kinds of radiation have different biologic characteristics and have advantages over using conventional photon beam radiation during treatment. The relative biological effectiveness (RBE) is used for many biological, clinical endpoints among different radiation types and is the only convenient way to transfer the clinical experience in radiotherapy with photons to another type of radiation therapy. However, the RBE varies dependent on the energy of the beam, the fractionation, cell types, oxygenation status, and the biological endpoint studied. Thus this review describes the concerns about RBE related to particle beam to increase interests of the Korean radiation oncologists’ society.

        • KCI등재

          Effect of Ethanol/water Solvent Ratios on the Morphology of Zein Nanofiber Mats and their Wettability

          최진현,김영화,염정현 한국염색가공학회 2011 韓國染色加工學會誌 Vol.23 No.4

          Zein is a hydrophobic protein produced from maize and has great potential in a number of industrial applications, such as food, food coating and food packaging. To obtain suitable electrospinning conditions for thinner and uniform zein nanofiber mats, a series of experiments was conducted on various volume ratios (v/v) of ethanol/water solutions with different zein concentrations. The prepared zein nanofiber mats were characterized by field emission scanning electron microscopy and contact angle measurements. Uniform zein fibers with a average diameter in the nanometer scale (300~500 nm)could be prepared from 30 wt.% zein in 7/3 (v/v) ethanol/water solutions.

        • KCI등재

          Congenital central hypoventilation syndrome combined with Hirschsprung disease diagnosed in the neonatal period

          최진현,오진희,김종현,고대균,홍승철 대한소아청소년과학회 2006 Clinical and Experimental Pediatrics (CEP) Vol.49 No.4

          Congenital central hypoventilation syndrome (CCHS) or Ondine's curse is a very rare sleep disorder that is the result of a congenital failure of the autonomic control of ventilation caused by insensitivity of the chemoreceptor to hypercapnea during sleep. Gastrointestinal motility disorders, particularly a congenital megacolon (Hirschsprung disease) is often combined with CCHS. This combination can be explained by a defect in the migration of neuronal cells from the neural crest (neurocristopathy) during the intrauterine period. A diagnosis of CCHS is made by confirming the failure of adequate ventilation in response to hypercapnea and hypoxia during sleep and the exclusion of other diseases. Young infants frequently show atypical clinical courses, and their conditions are frequently complicated with the long-term sequela of hypoxemic episodes. Therefore, a high index of suspicion and active treatment with mechanical ventilation are important for reducing recurrent hypoxemic episodes in the neonatal period. This paper reports the follow up of a case of CCHS in a neonate who showed frequent intractable apnea and cyanosis and was given artificial mechanical ventilation during sleep. Congenital central hypoventilation syndrome은 혈중 이산화탄소 증가와 저산소에 대한 자율 신경계와 호흡 조절 기능의 선천성 결함으로 호흡의 저환기가 주로 수면시에 발생하는 질환이다. 이는 신경 이주장애 질환(neurocristopathy)에 속한다고 알려져 있으며 선천성 거대결장 등의 질환과 잘 동반된다. 아직까지 확실한 완치법은 없는 상태이고 환아들은 평생을 환기 보조에 의존하여 생존해야 하며 적절한 환기 보조를 통해서 생존 기간을 연장할 수 있다. 저자들은 출생시부터 반복되는 수면시의 무호흡과 청색증이 있는 환아에서 congenital central hypoventilation 및 선천성 거대 결장이 동반된 1례를 경험하였기에 보고하는 바이다.

        • KCI등재

          정부회계 주요개념의 근본적 특성

          최진현,Yi-Qing Quan 한국정부회계학회 2004 정부회계연구 Vol.2 No.2

          일반적으로 기업회계의 기간이익은 당기 기업 활동의 유효성을 측정하는 척도로 사용된다. 이렇게 기업회계의 당기순이익이 기업 활동의 유효성을 측정하는 척도로 사용될 수 있는 근본적인 전제는 수익의 측정이 생산물이나 서비스가 다수의 공급자와 다수의 수요자가 참여하는 시장에서 결정되는 가격에 의존하기 때문이다.그러나 정부회계에서는 정부가 독점적 위치에 있기 때문에 수익이 다수의 공급자와 다수의 수요자가 참여하는 시장에서 결정되는 가격에 의존하는 것이 아니다. 따라서 기업회계의 당기순이익과 달리 정부회계의 수익과 비용의 대응결과인 순자산변동액이나 기금잔액변동액이 운영성과를 평가할 수 있는 지표가 아니라 집행결과를 나타내는 잔액에 지나지 않는다.정부회계에서 순자산변동액이나 기금잔액변동액이 펀드의 운영성과를 측정하는 지표로 이용하기 위해서는 수익을 객관적으로 측정하여 화폐가치로 환산하여 측정할 수 있는 기법의 개발이 필요하다. 예컨대 시장가격이 존재하지 않는 경우의 잠재가격 추정방법(shadow-pricing)을 응용하여 수익을 측정하는 기법 등을 개발해야 할 것이다.

        • KCI등재

          추간판 내 수핵 대체용 주사형 Poly(2-hydroxyethyl Methacrylate)계 하이드로젤

          최진현 한국생체재료학회 2007 생체재료학회지 Vol.11 No.2

          Poly(2-hydroxyethyl methacrylate-co-sodium methacrylate) (poly(HEMA-co-SMA)) hydrogel was synthesized in order to replace nucleus pulposus in a degenerated intervertebral disc without surgical excision and implantation of prosthesis. The aqueous mixture of HEMA, SMA, EGDMA, and redox initiators was gelled at 36.5oC within 10-15 minutes. The water content and compressive modulus of this hydrogel were higher than those of a natural nucleus pulposus. Poly(HEMA-co-SMA) injectable hydrogel was inserted successfully into a rabbit's degenerated disc. After 1 month, it was revealed that dehydration and fibrosis were prevented dramatically in a hydrogel-injected disc compared with a degenerated disc. From histology, fusion of macrophages or formation of foreign-body giant cells were not detected in a hydrogel-injected nucleus pulposus. Hence, poly(HEMA-co-SMA) injectable hydrogel is suggested as a feasible prosthesis which has physical properties and biostabilities enough to replace nucleus pulposus in a degenerated disc.

        • KCI등재후보

          建設業體의 環境費用認識에 관한 實證分析

          최진현,최인석 한국회계정보학회 2003 회계정보연구 Vol.20 No.-

          The function of environmental accounting is to provide measured data as an adequate measure of business organization’ success on the viewpoint of social climate such as pollution. global warming and acid rain. The environmental accounting is based on the general function of accounting system. Much of the accounting function involves measurements and communication of measured data as they relate to point in time and various segments. The environmental accounting information serve as indices to make possible useful analysis of social problems. The standards of identifying, measuring and disclosure of environmental cost accounting is not setting and the rate and degree of environmental cost information disclosure as supplemental footnotes is very low in Korean construction industry. So, this study is aimed at providing some criteria of the environmental cost accounting in Korean construction industry. The results of this study is as followings. First, the environmental cost accounting information is not disclosed in seventy percentage of Korean construction cooperations. Second, some criteria of the environmental cost accounting are construction capacity and detail major in Korean construction industry Third, .a criterion of construction capacity for distinction in separation of environmental accounting is three million Won in Korea. In conclusion, it is necessary to embody contents and methods of supplemental footnotes in detail and there will be disclosed the qualities and contents of environmental cost in comparable form between business organizations. Therefore, it is necessary to group small cooperations and the others for the new accounting standards in Korean construction industry. 본 연구는 한국의 건설업체들을 대상으로 질문지를 이용한 우편 조사방법을 통해 자료를 수집하고 질문지의 문항구성의 신뢰성과 타당성을 검증하기 위해서는 크론바하의 신뢰계수알파를 이용했다. 그리고 조사된 데이타는 로지스틱 회귀분석을 통해 공시여부에 미치는 영향요인을 검토하고, 죤슨-셰논 거리 분석을 통해서는 환경보전(환경보전에 대한 사회적 책임) 및 환경회계에 대한 인식(환경비용 측정의 중요성, 환경비용 공시의 필요성)에 관한 변수들이 세부업종, 시공능력 (기업규모) 등에 따라 군집이 가능하고 차이들이 존재하는지를 검토하였다. 차이가 존재하는 변수들에 따라 그릅핑된 세부집단별로 환경보전과 오염방지를 위한 여러 가지 회계적 적용방안을 생각해 보았다.

        • KCI등재

          Tumor Stage-Related Role of Radiotherapy in Patients with an External Auditory Canal and Middle Ear Carcinoma

          최진현,김세헌,고윤우,최은창,이창걸,금기창 대한암학회 2017 Cancer Research and Treatment Vol.49 No.1

          Purpose The purpose of this study was to evaluate the clinical outcomes of patients treated with radiotherapy (RT) for a carcinoma of the external auditory canal (EAC) and middle ear. Materials and Methods The records of 32 patients who received RT from 1990 to 2013 were reviewed retrospectively. The Pittsburgh classification was used to stage all the cancers (early stage, T1/T2 [n=12]; advanced stage, T3/T4 or N positive [n=20]). Twenty-one patients (65.6%) were treated with postoperative RT and 11 patients (34.4%) were treated with definitive RT. The median radiation doses for postoperative and definitive RT were 60 Gy and 64.8 Gy, respectively. Chemotherapy was administered to seven patients (21.9%). Results The 5-year overall survival and disease-free survival rates for all patients were 57% and 52%, respectively. The disease control rates for the patients with early stage versus advanced stage carcinoma were 55.6% (5/9) and 50% (6/12) in the postoperative RT group and 66.7% (2/3) and 37.5% (3/8) in the definitive RT group, respectively. Overall, 15 cases (14 patients, 46.7%) experienced treatment failure; these failures were classified as local in four cases, regional in one case, and distant in 10 cases. The median follow-up period after RT was 51 months (range, 7 to 286 months). Conclusion Patients with early stage carcinoma achieved better outcomes when definitive RT was used. Advanced stage carcinoma patients experienced better outcomes with postoperative RT. The high rate of distant failure after RT, with or without surgery, reflected the lack of a consensus regarding the best therapeutic approach for treating carcinoma of the EAC and middle ear.

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