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최인형,조유경,박준영,강동훈,박재명,최명규 대한소화기학회 2022 대한소화기학회지 Vol.80 No.5
Collagenous gastroduodenitis is a rare gastrointestinal disease diagnosed histologically by subepithelial collagen deposition in the lamina propria. Its clinical presentation is diverse. The authors encountered a 17-year-old female patient who complained of epigastric pain. Endoscopy revealed several deep ulcers in the gastric body. The gastric mucosa around the ulcer showed diffuse fine nodularity in the shape of cobblestones with open-type atrophy. The duodenal mucosa showed nodular lesions similar to those of the gastric mucosa. The gastric ulcer healed completely with proton pump inhibitor treatment. The patient was followed up, showing no remarkable mucosal change of stomach or duodenum for several years. Collagenous gastroduodenitis was diagnosed by repeated histologic examinations. This paper reports a rare case of chronic collagen gastritis with deep gastric ulcer and its long-term clinical progress.
S-596 Transmission of malignancy in kidney transplantation
서혜원,김인호,권오범,정재균,이선우,강동혁,정은교,최인형 대한내과학회 2016 대한내과학회 추계학술대회 Vol.2016 No.1
Highlight In kidney transplantation (KT), transmission of hidden malignancy from donor kidney to recipients is a disastrous event. Furthermore, immunosuppressive agent can facilitate rapid tumor growth and metastatic potential of malignancy. Our case showed transmitted malignancy from donor kidney, and we emphasize on careful examination of hidden malignancy of donor kidney before KT Case A 57-year-old male patient with end-stage renal disease(ESRD) secondary to hypertension received KT from a deceased donor and underwent an immunosuppressive therapy based on corticosteroid, tacrolimus and mycophenolate. After 2 months of KT, he complined of pain in allograft region. CT scan showed 9.5cm sized rim enhancing hypodense mass arising from renal sinus of transplanted kidney and lung, bone metastasis (Figure). We performed biopsy on the mass of graft kidney, and the result showed transitional cell carcinoma. Discussion Transplantation is the treatment of choice for most patients with ESRD. However, transplantation of biological material from a donor to a host unavoidably carries some risk of disease transmission, such as infection and malignancy. These malignancies are often more aggressive and associated with a poor prognosis due to immunosuppressive agents. Our case showed a transmitted malignancy from donor kidney which had progressed rapidly after use of immunosuppressive drugs. Therefore, we would like to emphasize on a careful examination of hidden malignancy of a donor kidney before KT and careful follow up after KT.