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조절되지 않는 신증후군 환아에서 대뇌 출혈 및 확산 강조 영상에서의 제한을 동반한 후두부 가역적 뇌병증 증후군 1예
정승미(Seung Mi Jung),최성은(Seong Eun Choi),김혜정(Hye Jeong Kim),안요한(Yo Han Ahn),이건희(Kon Hee Lee) 대한소아신경학회 2017 대한소아신경학회지 Vol.25 No.3
Posterior reversible encephalopathy syndrome (PRES) is a rare clinico-radiological syndrome that is characterized by an acute onset of headache, vomiting, visual abnormalities, confusion, and/or seizures and is typically accompanied with edema of predominantly posterior portions of the cerebral hemispheres. Here, we report a case of PRES with cerebral hemorrhage that occurred in a female pediatric patient with uncontrolled nephrotic syndrome. The patient s magnetic resonance imaging (MRI) studies showed asymmetric white matter abnormalities, cerebral hemorrhage, and restricted diffusion. After controlling her hypertension and nephrotic syndrome, her neurologic symptoms improved, and follow-up MRI findings revealed interval resolving of the white matter lesions.
단일 2차 기관에서 소아 마이코플라스마 폐렴 환자의 치료를 위한 스테로이드 사용 현황과 효과
유수지 ( Susie Yoo ),최성은 ( Seong Eun Choi ),전지영 ( Jiyoung Chun ),안요한 ( Yo Han Ahn ),조기영 ( Ky Young Cho ),이용주 ( Yong Ju Lee ),성태정 ( Tae Jung Sung ),이건희 ( Kon Hee Lee ) 대한천식알레르기학회(구 대한알레르기학회) 2018 Allergy Asthma & Respiratory Disease Vol.6 No.2
Purpose: Steroids can be used as an adjuvant therapy in the management of mycoplasma pneumonia, but no definite guidelines for the use of steroids have been established. The purpose of this study was to analyze the current usage and effects of steroids in the management of childhood mycoplasma pneumonia in a secondary hospital in Korea. Methods: We retrospectively reviewed the medical records of 152 patients who were admitted due to mycoplasma pneumonia. The patients were divided into 3 groups as follows: those who did not use steroids (81 patients, 53%), those who used steroids after their fever subsided (42 patients, 28%) and those who used steroids during fever (29 patients, 19%). Results: In decreasing order of values, the duration of fever during hospitalization (60.0±40.2 hours vs. 37.3±28.5 hours vs. 29.7±29.5 hours, P=0.006) and duration of hospitalization (5.9±1.7 days vs. 5.0±1.4 days vs. 4.0±1.5 days, P<0.001) were reported in the group which received steroids during fever, the group which received steroids after the fever subsided and the group which did not receive steroids. In the group which received steroids during fever, patients with early steroid use (within 24 hours) had a shorter fever duration in the hospital (12.0 hours vs. 73.5 hours, P<0.001) and a hospitalization duration (5.0 days vs. 6.5 days, P=0.007) than those with late steroid use (after 24 hours). Conclusion: Steroids were used in 47% of patients with mycoplasma pneumonia. The patients who received early steroids had a shorter fever duration and a shorter hospital stay than those who received late steroids. (Allergy Asthma Respir Dis 2018;6:122-127)
권오상 ( Oh Sang Kwon ),최성한 ( Seong Han Choi ),김주현 ( Ju Hyun Kim ) 대한소화기학회 2015 대한소화기학회지 Vol.66 No.6
Inflammation is one of the most prominent characteristic features of chronic liver disease, liver fibrosis, cirrhosis, and hepatocellular carcinoma (HCC). Most of HCC cases develop in patients with cirrhosis and cirrhosis develops in patients with chronic liver inflammation. Therefore, there is no doubt that there exist some strong connection among inflammation, fibrosis, and cancer. In fact, chronic unresolved inflammation is associated with persistent hepatic injury and concurrent regeneration, leading to sequential development of fibrosis, cirrhosis, and eventually HCC. This review will discuss the common mechanism of inflammation and fibrosis in chronic liver diseases, and then demonstrate why HCC develops in inflammatory and fibrotic conditions.
박철숙(Park, Chal Sook),장광수(Jang, Kwang Su),한주헌(Han, Joo Heon),노찬래(Noh, Chan Rae),이상석(Lee, Sang Seok),최성도(Choi, Seong Do),임재한(Lim, Jae Han),장지웅(Jang, Ji Woong) 대한토목학회 2022 대한토목학회 학술대회 Vol.2022 No.10
영천댐 안정성 강화사업의 일환으로 건설중인 신설 취수탑은 고 심도의 수위를 유지한 상태에서 원형 벽강관 가물막이를 설치한 후 내부에서 비상방류 설비인 터널을 35m 굴착하여 관통하는 것으로 계획되었다. 벽강관 가물막이 시공 후 터널의 상단에 대한 차수 그라우팅을 실시하고 천단부의 보강작업 후 선진시추를 통해 기반암의 상태를 확인하였으며 N.A.T.M. 공법으로 굴착을 완료하였다. 향후 안전성 강화사업시 신설 취수탑과 연결되는 비상방류 터널의 설계 및 적용이 가능한 기술이라고 판단된다.
AP 입자가 HTPB/AP 추진제의 물리적 특성에 미치는 효과
임유진(Yoo Jin Yim),박은지(Eun Ji Park),권태하 (Tae Ha Kwon),최성한(Seong Han Choi) 한국추진공학회 2016 한국추진공학회지 Vol.20 No.1
The viscosity and mechanical property of HTPB/AP composite solid propellant are profoundly affected by particle size of AP. In HTPB/AP propellant formulated by two mode of AP size such as 190 μm and 7 μm, the propellant was found to be much less viscose at end of mix when coarse/fine AP ratio is ranged from 70/30 to 60/40 due to high solid packing fraction. It was shown that the toughness of tensile strength test for HTPB/AP propellant increased with the increase in coarse AP. Considering both lower viscosity and better tensile strength, the optimum ratio of AP coarse/fine was estimated to be 70/30.
AP 입자가 HTPB/AP 추진제의 물리적 특성에 미치는 효과
임유진(Yoojin Yim),박은지(Eun Ji Park),권태하(Tae Ha Kwon),최성한(Seong Han Choi) 한국추진공학회 2015 한국추진공학회 학술대회논문집 Vol.2015 No.11
HTPB/AP계 혼합형 고체 추진제의 점도와 기계적 특성은 산화제인 AP의 입자 크기에 크게 영향을 받는다. 190 μm의 크기의 큰 입자와 7 μm 크기의 작은 입자 AP를 사용한 HT{B/AP 추진제에서 큰 입자/작은 입자의 비율이 70/30~60/40 범위에서 매우 낮은 점도를 나타냈는데, 이것은 고체입자의 충전율이 높은 상태이기 때문이다. 추진제의 인장강도 시험에서 toughness는 큰 입자의 함량이 많아질수록 증가하는 것으로 나타났다. 낮은 점도와 좋은 인장강도를 동시에 고려할 때, AP 큰 입자와 작은 입자를 70/30 비율로 사용하는 것이 가장 효과적인 것으로 평가되었다. The viscosity and mechanical property of HTPB/AP composite solid propellant are profoundly affected by particle size of AP. In HTPB/AP propellant formulated by two mode of AP size such as 190 μm and 7 μm, the propellant was found to be much less viscose at end of mix when coarse/fine AP ratio is ranged from 70/30 to 60/40 due to high solid packing fraction. It was shown that the toughness of tensile strength test for HTPB/AP propellant increased with the increase in coarse AP. Considering both lower viscosity and better tensile strength, the optimum ratio of AP coarse/fine was estimated to be 70/30.