담즙산에 의한 위 점막 손상

조현홍,서정일,이경희,김태년,정문관,이현우,최원희,양창헌 영남대학교 의과대학 1992 Yeungnam University Journal of Medicine Vol.9 No.2

십이지장으로 분비되고 위내로 역류될 수 있는 bile acid가 위점막에 끼치는 영향을 알아보기 위해 체중 200-250gm전후의 Sprague-Dawley흰쥐를 사용하여 pH3인 염산과 TCDA 15mM혼합용액을 위장내에 주입하고 같은 산도의 염산을 위장내로 투여한 대조군과 비교 조사한 결과 다음과 같은 성적을 얻었다. TCDA에 의한 위점막 손상은 TCDA 투여후 75분이 지난 후 제일 저명하게 나타났고 15 분, 30분, 120분 및 150분에는 뚜렷한 변화를 관찰할 수 없었다. TDCA 투여후 75분에 나타나는 소견으로는 점막과 점막하조직의 울혈, 혈관 확장, 임파선 확장, 부종 등을 나타내었으며 시간이 경과함에 따라 혈관 확장 및 부종은 점차 소실되는 소견을 나타내었다. 이상의 결과로 보아 TCDA가 급성 위점막 손상을 일으킬 수 있지만 만성적 위점막 손상에 대해서는 여러 조건하에서 더 많은 연구가 있어야 할 것으로 사료된다. To investigate the effect of bile acid on gastric mucosa, we performed biologic test using Sprague-Dawley rat. Mixture solution of TDCA 15mM and HCl of pH 3 was given into stomach to one group and HCl of pH 3 was given into stomach to another group. The significant gastric mucosal change was vasodilatation and edema, that was disappeared progressively. These findings suggest the bile acid can damage gastric mucosa.

만성 신부전 환자의 영양 상태에 관한 연구

조현홍(Hyun Hong Cho),김종명,이재익(Jae Yik Lee),윤경우(Kyung Woo Yoon),이현우(Hyun Woo Lee),김경동(Kyung Dong Kim),김정숙(Chung Sook Kim) 대한내과학회 1989 대한내과학회지 Vol.37 No.5

N/A The purpose of the present study was to evaluate the nutritional status of 46 chronic renal failure (CRF) patients. Forty-one chronic renal failure patients and 61 normal control persons were included in the study. There were no differences in mean age and sex distribution between the two groups. We measured serum transferrin with a radioimmunodiffusion method, serum albumin with a bromo cresol Green method and plasma zine with atomic absorption spectrometry. The anthropometric measurements were triceps skinfold thickness (TSF) and midarm circumference (MAC), and from these, midarm muscle circumfrence (MAMC), midarm muscle area (MAMA), and midarm fat area (MAFA) were calculated. The results were as follows: 1) The mean height of the CRF group (164.11±6.50 cm: N=46) was not different from that of the control group (164.01±8.17cm: N=40), but the mean weight of the CRF group (55.27±8.33kg: N = 4ti) was significantly (p=0.33) lower than that of the control group (59.41±9.26kg: N=39). 2) The mean MAMA of the CRF group (40.81±10.11㎠. N =46) was significantly (p=0.005) lower than that of the control group (46.35±9.73㎠. N=61), and the mean MAFA of the CRF group (13.34±7.56㎠: N=46) was significantly (p=0.005) lower than that of the control group (18.03+ 8.97㎠: N =61). 3) The mean serum transferrin of the CRF group (172.23±26.70mg/dl: N=46) was significantly (p=0) lower than that of the control group (307.14±67.23mg/ddl: N =41), the mean plasma zinc of the CRF group (69.56±42.93㎍/dl: N =46) was significantly (p=1.90E-6) lower than that of the control group (123.38±55.49㎍/dl: N = 42), and the mean seurm albumin of the CRF group (3.81±0.52g/dl: N=16) was significantly (p=4.00E-15) lower than that of the control group (4.7±0.52 g/dl: N=41). 4) There was a positive correlation (r=0.78, p=0.00) between MAMA and body weight, a positive correlation (r=0.368, p=0.044) between MAMA and MAFA in CRF patients. 5) There was a positive correlation (r=0.416, p=0.0039) between plasma zinc and serum transferrin, but a negative correlation (r=0.31, p=0.034) between plasma zinc and body weight in CRF patients. 6) There was no correlation between the duration of hemodialysis and body weight, MAMA, serum transferrin, and plasma zinc. We concluded that 1) there were impairments of protein, fat and trace metal metabolism in CRF patients, 2) hemodialysis duration was not a factor influencing the nutritional status of CRF patients, and 3) MAMA, MAFA, serum transferrin and plasma zinc would be good indices to reflect the nutritional status of CRF patients.

Rifampin에 의한 급성신부전 1예

권경순,조현홍,윤경우,이현우 대한신장학회 1988 Kidney Research and Clinical Practice Vol.7 No.1

Acute renal failrue due to rifampin is relatively un- common side-effect. Recently the authors experienced a cases of rifampin induced acute renal failrue in a 48-year-old female patient. She was diagnosed as pulmonary tuberculosis 2 years ago. Since then she selfmedicated various anti-tuberculous drugs. On history-taking it was evident that she took rifampin intermittently. About 4 months before the present episode there was a history of self-limited oliguria history after rifampin administration. During that time she was hospitalized at a local hospital and anti-tuberculous medication was discontinued for 4 months. Again she took a single dose of rifampin (450mg) and fever, chill, itching, nausea, vomiting, abdominal pain and reddish mucoid stool developed. Oliguria also occurred and abdominal pain became severe. She was referred to Yeungnam University Medical Center and was treated with 8 times of hemodialysis. Oliguric phases lasted about 11 days and she recovered slowly but without any sequelae. On 9th hospital day we prescribed isoniazid, ethambutol and cycloserine and no side-effect was noted. There was no evidence of hemolysis and we presume a hypersensitivity reaction was operating in this case. The authors report a case of rifampin-induced acute renal failure with review of literature.

Rifampin에 의한 급성 신부전 1예

권경순,조현홍,윤경우,이현우 대한신장학회 1988 대한신장학회잡지 Vol.7 No.1

스포츠교육학 : 고등학교 우수팀과 비우수팀 검도 지도자의 코칭 행동

박형란(HyoungRanPark),조현홍(HyunHongCho),이한주(HanJooLee) 한국체육학회 2004 한국체육학회지 Vol.43 No.5

The purpose of this study was to analyze and compare coaching behaviors of successful and less successful Kendo coaches. Research questions were: (a) Are there differences between successful and less successful coaches when they are coaching beginning and advanced level players? (b) What are the differences between successful and less successful coaches regarding their instructional suggestions for performance improvement? Four coaches, (i.e. two successful and two less successful coaches) participated in this study. Coaches were asked to teach basic skills for the beginning level players and advanced skills for advanced level Kendo players in a College team Coaching behaviors of successful and less successful coaches were analyzed using the Arizona State University Observation Instrument (ASUOI) developed by Lacy and Darst (1989) and the Qualitative Measures of Teaching Performance Scale (QMTPS) developed by Rink and Werner (1989). Results of this study revealed that successful coaches showed more emphasis on pre- and post-instruction categories while less successful coaches concurrent instruction in the ASUOI. Also, successful coaches showed more concerns on informing and applying task while less successful coaches showed more extending and repeat task in the QMTPS. In addition, successful coaches showed higher scores than less successful coaches on clarity, demonstration and student responses appropriate to task focus in the task presentation categories.

막성 간내 하공 정맥 폐색증 1 예

김종명(Jong Myung Kim),조현홍(Hyeon Hong Jo),신동구(Dong Goo Sin),정문관(Moon Kwan Chun),이헌주(Heon Ju Lee),이현우(Hyeon Woo Lee) 대한내과학회 1989 대한내과학회지 Vol.36 No.4

N/A The most common cause of hepatic outflow obstruction in the world is idiopathic membranous obstruction of the inferior vena cava (MOVC), but in Korea only a few articles have reported it. We report here a case of a 19-year old female with MOVC. As with and other cases of MOVC, there was no evidence of chronic or specific symptoms and signs of liver disease except fatigability, abdominal distension, and edema on the lower legs for several months. The early recognition of MOVC can be difficult but its diagnosis is important sincs, in many cases, the obstruction may be surgically corrscted moreover in Korea, MOVC must be ruled out from other various chronic liver disease caused by related with hepatitis B

원발성 간세포암 환자의 혈청 NOVEL γ - GTP Isoenzyme

정문호(Moon Ho Chung),조현홍(Hyun Hong Cho),권영수(Young Su Kweon),서혜상(Hye Sang Seo),이헌주(Heon Ju Lee),이현우(Hyun Woo Lee),김재룡(Jae Ryong Kim) 대한내과학회 1989 대한내과학회지 Vol.36 No.5

N/A γ-glutamyl transpeptidase (γ -GTP) was examined to see the incidence and specificity of the novel band in the field of diagnosis of primary hepatocellular carcinoma. Serum γ -GTP was fractionated by polyacrylamide gradient gel electrophoresis from the sera of 50 patients with various hepatobiliary diseases, including 20 with primary hepatocellular carcinoma (HCC). γ -GTP isoenzymes in the sera were separated by this method into 10 bands. Novel band, which was seen in the region near the ceruloplasmin, was detected in 15 of 20 patients with hepatocellular carcinoma (75%). Specific γ -GTP was found in 25% of HCC patients with alphafetoprotein (AFP) levels below 400 ng/ml. The incidence of this isoenzyme was independent of the clinical stage as classified by liver scanning, Even in Stage I, where filling defects were not seen, the incidence was remarkable. We conclude that this novel γ -GTP isoenzyme seems to be 1) a useful diagnostic index for hepatocellular carcinoma and 2) a relatively useful marker for early detection of HCC patients, even in Stage I, which has no filling defect on the liver scan. In addition, we need more studies for confirmation of the usefulness of γ -GTP isoenzyme for diagnosis of HCC patients with lower serum AFP levels.

관광지의 속성과 관광객의 재방문의도

모영미(Mo, Young Mi),조현홍(Cho, Hyun Hong),유창남(Ryu, Changnam),전기흥(Jeon, Ki-Heung) 한국문화산업학회 2014 문화산업연구 Vol.14 No.1

과거의 관광지는 단지 아름답고 색다른 자연이 전부였다. 그러나 이러한 관광에 대해서 관광객은 쉽게 질릴 수 있다. 따라서 최근의 관광은 자연관광이 아닌 인문관광으로 변화를 모색하고 있다. 이에 대해서 본 연구는 관광객은 어떤 관광지를 좋아할까?에 대한 의문으로 시작하였다. 본 연구는 관광지의 속성을 4개의 독립변수로 구성하였다(매력도, 편의성, 친절함, 정보성). 즉, 각 독립변수가 관광지 신뢰와 관광지 감성에 어떤 영향을 미치는지를 파악하였다. 그리고 관광지 신뢰와 감성이 재방문의도에 어떤 영향을 미치는지를 파악하였다. 조사결과, 매력도는 관광지 신뢰 및 감성에 긍정적인 영향을 미쳤다. 편의성은 관광지 신뢰에만 영향을 미쳤다. 친절함은 관광지 신뢰 및 감성에 긍정적인 영향을 미쳤다. 정보성은 관광지 신뢰에만 영향을 미쳤다. 관광지 신뢰는 관광지 감성 및 재방문의도에 긍정적인 영향을 미쳤다. 관광지 감성은 재방문의도에 긍정적인 영향을 미쳤다. In the past years, most of good tourist places were thought to be beautiful and different natures. But, most tourists were sick and tired of this kind of tourism. And so, the new trend of tourism has been changed from natural tourism to humanitarian tourism. This study started with the question about which tourist place travellers want to go to. In this study, the attributes of tourist place are composed of four independent variables(attractiveness, convenience, kindness, information). The authors figured out how each of independent variables affected the trust and emotion of tourist place. And also, the authors investigated the causal relationships between the trust and the emotion of tourist place and the intention of revisit. As research results, the attractiveness had a positive effect on the trust of tourist place and the feeling. The convenience had positively affected only the trust of tourist place. The kindness had a positive impact on both the trust of tourist place and the feeling. The causal relationship between the informativeness and the trust of tourist place was shown to be positively related. The trust of tourist place has positively affected the feeling of tourist place and the intention of revisit. The intention of revisit was positively affected by the feeling of tourist place. 과거의 관광지는 단지 아름답고 색다른 자연이 전부였다. 그러나 이러한 관광에 대해서 관광객은 쉽게 질릴 수 있다. 따라서 최근의 관광은 자연관광이 아닌 인문관광으로 변화를 모색하고 있다. 이에 대해서 본 연구는 관광객은 어떤 관광지를 좋아할까?에 대한 의문으로 시작하였다. 본 연구는 관광지의 속성을 4개의 독립변수로 구성하였다(매력도, 편의성, 친절함, 정보성). 즉, 각 독립변수가 관광지 신뢰와 관광지 감성에 어떤 영향을 미치는지를 파악하였다. 그리고 관광지 신뢰와 감성이 재방문의도에 어떤 영향을 미치는지를 파악하였다. 조사결과, 매력도는 관광지 신뢰 및 감성에 긍정적인 영향을 미쳤다. 편의성은 관광지 신뢰에만 영향을 미쳤다. 친절함은 관광지 신뢰 및 감성에 긍정적인 영향을 미쳤다. 정보성은 관광지 신뢰에만 영향을 미쳤다. 관광지 신뢰는 관광지 감성 및 재방문의도에 긍정적인 영향을 미쳤다. 관광지 감성은 재방문의도에 긍정적인 영향을 미쳤다. In the past years, most of good tourist places were thought to be beautiful and different natures. But, most tourists were sick and tired of this kind of tourism. And so, the new trend of tourism has been changed from natural tourism to humanitarian tourism. This study started with the question about which tourist place travellers want to go to. In this study, the attributes of tourist place are composed of four independent variables(attractiveness, convenience, kindness, information). The authors figured out how each of independent variables affected the trust and emotion of tourist place. And also, the authors investigated the causal relationships between the trust and the emotion of tourist place and the intention of revisit. As research results, the attractiveness had a positive effect on the trust of tourist place and the feeling. The convenience had positively affected only the trust of tourist place. The kindness had a positive impact on both the trust of tourist place and the feeling. The causal relationship between the informativeness and the trust of tourist place was shown to be positively related. The trust of tourist place has positively affected the feeling of tourist place and the intention of revisit. The intention of revisit was positively affected by the feeling of tourist place.