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양웅석(Oong Sheuck Yang),제영성(Young Sung Jae),허윤(Yoon Huh),조성락(Sung Rag Cho),이정국(Jeong Koog Lee),조군제(Goon Jae Cho) 대한소화기학회 1982 대한소화기학회지 Vol.14 No.1
N/A Sixty-three patients with esophageal varices were selected in whom endoscopic examination was performed at the Busan National University Hospital, September, 1982 and February, 1982 The esophageal varices were classified into three grades from the endoscopical point of point of view in accordance with Sesokos method of classification. A study was done for the relationship between the endoscopical findings of esophageal varices, clinical findings and spleen visualization by 198Au liver scanning. The results obtained were as follow: 1) Among 63 cases with esophageal varices, the grade of esophageal varices was severe in 31.7%, moduate in 39.7%, and mild in 28.6%. 2) In 44 bleeding patients with esophageal varices, there was significant correlation between the grade of esophageal varices and the frequency of upper gastrointestinal bleeding. Severe esophageal varices were associated with a high risk of bleeding. As the cause of upper gastrointestinal bleeding, ruptured esophageal varices (54. 5%) and hemorrhagic gastritis (24.0%) were more frequent. Bleeding source could not be observed in 11 4% of bleeding cases. 3) The grade of esophageal varices had neither significant relationship with abdominal venous dilatation nor with ascites. There was parallel relationship between the grade of esophageal varices and splenomegaly. The larger splenomegaly was, the higher grade of esophageal varices was present. 4) Somewhat correlation was observed between spleen visualization by 198Au liver scanning and the grade of esophageal varices but not statsically significant.
유방현(Bang Hyun Liu),김홍범(Hong Bum Kim),김두연(Doo Yeon Kim),제영성(Young Sung Jae),양웅석(Oong Seok Yang),허윤(Yoon Huh) 대한소화기학회 1981 대한소화기학회지 Vol.13 No.2
This report present a case of double pylorus associated with Gout and peptic ulcer, which is very rare in the world. This patient was 60-years oId male who visited local clinic with the chief complaints of intermittent ankle swelling and pain for 8 years, epigastric pain and indigestion for 1 month. The patient was transferred to Busan National University Hospital because of suspected Gout with peptic ulcer. UGI Barium study(April 2, 1981) showed the stomach was orthotonic in type and ulcer crater at the pyloric antrum of stomach. Duodenum was normal. Control endoscopy revealed another plyoric ring which looks like accessory and congenital anomaly, and there showed scar-stage ulcer with mucosal fold convergency in prepylorus.
최정숙(Jeong Sug Choi),류수현(Su Heon Ryu),유대성(Dae Seong Yu),오정열(Jeong Yeol Oh),김영묵(Young Mook Kim),이충원(Choong Won Lee),제영성(Yeong Sung Jae),이준상(Joon Sang Lee) 대한소화기학회 1995 대한소화기학회지 Vol.27 No.3
Hepatosplenic tuberculosis is manifested commonly as miliary form, but the isolated form of hepatosplenic tuberculosisis is extremity rare. The local form of hepatosplenic tuberculosis is trans- ported to liver from intestine through portal vein. Basic pathology is granuloma. We described a patient with tuberculous abscess of liver and spleen proved by computed tomography and microbial identification. Liver specimen obtained by CT-guided fine needle aspiration showed Mycobacterium tuberculosis. After one month of antituberculous medication, the patients condition has been improved. Thus, the local form of hepatic tuberculosis must be differentiated from similar diseases, because it can be cured dramatically by antituberculous medication. (Korean J Gastroenterol 1995;27:363 - 368)
최정숙(Jeong Sug Choi),류수현(Su Heon Ryu),오정열(Jeong Yeol Oh),이충원(Choong Won Lee),김영묵(Young Mook Kim),임종섭(Jong Sub Lim),제영성(Young Sung Jae),유방현(Band Hyun Liu) 대한소화기학회 1996 대한소화기학회지 Vol.28 No.3
Skull metastases of primary hepatocellular carcinoma are very rare, even in the Orient and the Africa where this carcinoma is one of the common rnalignancies. However, although these skull tnetastases are rare, this diagnosis must be considered when an skull tutnor has a metastatic appearance, especially in cirrhotic patients or heavy alcoholics. This lesion is extremely hypervas- cular, and precautions for hemorrhage must be taken before any procedure, even a biopsy is done. The prognosis remains lethal and average survival time after the time of diagnosis is under 6 months, but appropriate local surgical resection to the skull region and systemic control with chemotheraphy and radiotheraphy can result in improved survival. The patient reported here may be valuable in presenting an unusual occurance of primary hepatocellular carcinoma with metastases to the skull. (Korean J Gastroenterol 1996; 28:415 - 420)
NANB 간질환 환자에서 2세대 효소 면역 검사법과 중합효소 연쇄 반응법을 이용한 C형 간염바이러스 감염의 진단
이복근(Bock Gyeon Lee),권기호(Ki Ho Kwon),박양훈(Yang Hun Park),김한성(Han Sung Kim),정찬수(Chan Su Jeong),제영성(Young Sung Jae),이준상(Joon Sang Lee),유방현(Bang Hyun Liu),박영홍(Young Hong Park),이기영(Kee Young Lee) 대한소화기학회 1994 대한소화기학회지 Vol.26 No.5
N/A The first-generation enzyme linked imrnumosorbent assay(ELISA) method to detect hepati- tis C virus(HCV) has been used with relatively good sensitivity in the diagnosis of chronic non A non B hepatitis infecton, but its sensitivity in cases of acute hepatitis remains poor. The secondeneration ELISA which uses recombinant proteins and synthetic peptides from both structural and nonstructural regions increases the sensitivity in diagnosing HCV infection, and diminishes the number of false-positive reactions. The polymerase chain reaction(PCR) has been used to detect infectivity of anti HCV positive patients more accurately, to evaluate ver- tical transmission, and to monitor the response to antiviral ther~apy for chronic HCV infection. Serum samples from 35 patients with non A non B type liver disease were tested by the secondeneration ELISA and the PCR to evaluate the roles of hepatitis C viral infections in NANB patients. HCV RNA was detected by single polymerase c~t~ain reaction technique using primers deduced from the 5noncoding region of HCV genome. Among the 35 patients, 27 pa- tients were positive for anti HCV (Group A), while 8 were negative for anti HCV(Group B). Among anti HCV positive patients, 11% and 33% o~f patients were related to the transfu- sion and acupuncture, respectively. We could detect HCV RNA in the sera from 27 patients (100%) in the group A and 4 patients(50%) in the group B. We conclude that the combination methods of secondeneration ELISA plus PCR reduce the chance of false diagnosis of HCV infection compared to the first generation ELISA and the PCR can be used to diagnose HCV infection in anti HCV negative hepatitis patients.(Ko- rean J Gastroenterol 1994; 26; 825 832)
Diphenylhydantoin에 의한 중증 재생불량성 빈혈 1예
김한성,한경근,김종현,김경환,조강일,정찬수,정철호,제영성,임창현 대한내과학회 1993 대한내과학회지 Vol.44 No.5
DPH는 경련치료제 및 예방요법제로 가장 널리 사용되어 왔으며, 이 약제에 의한 부작용은 아주 드물게 조혈장기에 손상을 줄 수 있다. 저자들은 항경련제로 DPH 사용 중 갑자기 발생한 중중 재생불량성 빈혈 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Since 1938, Diphenylhydantoin (DPH) has remained one of the most widely used anticonvulsants for treatment and prevention of seizures. DPH may induce serious damage to the hematopoietic system. Especially, DPH induced severe aplastic anemia is one of the most severe complication and its incidence is extremely rare. We recently expreienced one case of severe aplastic anemia in 52-year-old woman following administration of DPH. Litreature was reviewed briefly.