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조진호 ( Jin-ho Cho ),박양훈 ( Yang-hun Park ),박광철 ( Gwang-cheol Park ),최선오 ( Sun-oh Choi ) 한국정보처리학회 2020 한국정보처리학회 학술대회논문집 Vol.27 No.2
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NANB 간질환 환자에서 2세대 효소 면역 검사법과 중합효소 연쇄 반응법을 이용한 C형 간염바이러스 감염의 진단
이복근(Bock Gyeon Lee),권기호(Ki Ho Kwon),박양훈(Yang Hun Park),김한성(Han Sung Kim),정찬수(Chan Su Jeong),제영성(Young Sung Jae),이준상(Joon Sang Lee),유방현(Bang Hyun Liu),박영홍(Young Hong Park),이기영(Kee Young Lee) 대한소화기학회 1994 대한소화기학회지 Vol.26 No.5
N/A The first-generation enzyme linked imrnumosorbent assay(ELISA) method to detect hepati- tis C virus(HCV) has been used with relatively good sensitivity in the diagnosis of chronic non A non B hepatitis infecton, but its sensitivity in cases of acute hepatitis remains poor. The secondeneration ELISA which uses recombinant proteins and synthetic peptides from both structural and nonstructural regions increases the sensitivity in diagnosing HCV infection, and diminishes the number of false-positive reactions. The polymerase chain reaction(PCR) has been used to detect infectivity of anti HCV positive patients more accurately, to evaluate ver- tical transmission, and to monitor the response to antiviral ther~apy for chronic HCV infection. Serum samples from 35 patients with non A non B type liver disease were tested by the secondeneration ELISA and the PCR to evaluate the roles of hepatitis C viral infections in NANB patients. HCV RNA was detected by single polymerase c~t~ain reaction technique using primers deduced from the 5noncoding region of HCV genome. Among the 35 patients, 27 pa- tients were positive for anti HCV (Group A), while 8 were negative for anti HCV(Group B). Among anti HCV positive patients, 11% and 33% o~f patients were related to the transfu- sion and acupuncture, respectively. We could detect HCV RNA in the sera from 27 patients (100%) in the group A and 4 patients(50%) in the group B. We conclude that the combination methods of secondeneration ELISA plus PCR reduce the chance of false diagnosis of HCV infection compared to the first generation ELISA and the PCR can be used to diagnose HCV infection in anti HCV negative hepatitis patients.(Ko- rean J Gastroenterol 1994; 26; 825 832)
악성화및 간전이를 동반한 Peutz-Jeghers 증후군
서보정(Bo Jeong Seo),이복근(Bok Geun Lee),박양훈(Yang Hun Park),권기호(Ki Ho Kwon),김영묵(Young Mook Kim),이충원(Choong Won Lee),이동윤(dong Yoon Lee),이준상(Joon Sang Lee),백옥지(Ok Ji Paik) 대한소화기학회 1994 대한소화기학회지 Vol.26 No.2
The Peutz-Jeghers syndrome, characterized by pigmentation of the skin and mucous membranes and gastrointestinal polyposis of harmatomatous variety, has been well docu- mented, there have been conflicting view, however, as to frequency with which malignant change occurs in the polyp. There are insufficient data to establish this syndrome as a precancerous condition but documented cases of gastrointestinal cancer arising in this syndrome have been reported with an incidence of 2 3%. This report is concerned with our experience with a case of Peutz Jeghers syndrome with adenocarcinoma as arising in colonic polyps, which metastasized to omentum and regional lymph nodes and liver. Histologically the polyps were mostly harmatomatous and one was transformed into adenocarcinoma and liver showsed adenocarcinoma in the metastatic sites.(Korea J Gastro- enterol 1994;26:363-368)
이준상(Joon Sang Lee),김한성(Han Sung Kim),박양훈(Yang Hun Park),한경근(Gyung Geun Han),권기호(Ki Ho Kwon),이동윤(Dong Yun Lee) 대한소화기학회 1993 대한소화기학회지 Vol.25 No.5
The most common causes of biliary tract obstruction are choledocholithiasis and neoplastic disease. Obstructive jaundice produced by tuberculous lymphadenitis without pulmonary or miliary tuberculosis is quite rare. We are reporting a case of young man who has weight loss, and the subsequent development of jaundice who was found to have tuberculosis of the lymph nodes surrouning the biliary tract. The lymph node was obtained for frozen biopsy and it was confirmed to be tuberculous granuloma. Choledochoduodenostomy with lymph node dissection was performed. The patient also continued to receive antituberculous chemotherapy
D - Penicillamine에 의한 담즙 정체성 황달
이준상(Joon Sang Lee),백옥지(Ok Ji Paik),김한성(Han Sung Kim),박성수(Sung Su Park),한경근(Kyung Keun Han),박양훈(Yang Hun Park),제영성(Yeong Sung Jae),박욱화(Wook Hwa Park) 대한소화기학회 1993 대한소화기학회지 Vol.25 No.4
Since 1966, D-Penicillamine has been used in the management of scleroderma. However, its therapeutic usefulness has been limited by a high incidence of a variety of adverse reactions. Cholestatic jaundice secondary to D-Penicillamine administratiori has been reported infrequently. We have experierced a case of acute chotestatic jaundice in a patient with scleroderma treated with D- Fenicillamine. We have encountered a patients who recovered from this complication whn D Penicillamine therapy was withdrawn. Literature was re!iewed briefly.
Primary Empty Sella Syndrome 에 동반된 뇌하수체 기능저하중 및 중추성 요붕증 1 예
최정숙,김한성,권기호,박양훈,제영성,이복근,서보정,오정열 대한내과학회 1994 대한내과학회지 Vol.47 No.2
The empty sella syndrome results from and extension of the subarachnoid space into an intrasellar portion with expansion of sella and flattening of the pituitary gland. The empty sella syndrome is distinguisted between $quot;primary$quot; (without prior surgical or radiotherapeutic procedurea) and $quot;secondary$quot; (following such procedure) cases. In this syndrome, the endocrine function is usually normal and this syndrome which is accompanied with endocrinologic abnormalities and diabetes insipidus is rarely reported. We discribed a patients of central type of diabetes insipidus, hypoptuitarism including growth retardation and sexual infantilism in the primary empty sella syndrome. So we present this case with a review of the literature.