NCA 물성에 따른 극미세 피치 COG (Chip on Glass) In, Sn 접합부의 신뢰성 특성평가

정승민,김영호,Chung Seung-Min,Kim Young-Ho 한국마이크로전자및패키징학회 2006 마이크로전자 및 패키징학회지 Vol.13 No.2

NCA의 물성이 미세피치 Chip on glass (COG) 접합부의 신뢰성에 미치는 영향을 연구하였다. Si 위에 Sn을, 유리기판 위에 In을 열증발 방법으로 증착하고 lift-off 방법을 이용하여 $30{\mu}m$ 피치를 가지는 솔더범프를 형성하였으며 열압착 방법으로 $120^{\circ}C$에서 In 범프와 Sn 범프를 접합하였다. 접합할 때 세 종류의 Non conductive adhesive (NCA)를 적용하였다. 신뢰성은 $0^{\circ}C$와 $100^{\circ}C$ 사이로 열충격시험을 2000회까지 실시하여 평가하였다. 4단자 저항측정법을 이용하여 접합부의 저항을 측정하였다. 필러의 양이 증가할수록 열충격시험 후 접합부의 저항이 가장 적게 증가하여 신뢰성이 우수하였다. 필러의 양이 증가할수록 NCA의 열팽창이 작아지기 때문이다. We developed a bonding at low temperature using fine pitch Sn and In bumps, and studied the reliability of the fine pitch In-Sn solder joints. The $30{\mu}m$ pitch Sn and In bumps were joined together at $120^{\circ}C$. A non conductive adhesive (NCA) was applied during solder joining. Thermal cycling test ($0^{\circ}C-100^{\circ}C$, 2 cycles/h) of up to 2000 cycles was carried out to evaluate the reliability of the solder joints. The bondability was evaluated by measuring the contact resistance (Rc) of the joints through the four point probe method. As the content of filler increased, the reliability improved in the solder joints during thermal cycling test because the contact resistance increased little. The filler redistributed the stress and strains from the thermal shock over the entire joint area.

Lipid Mediator에 의한 적혈구 Microvesicle 생성에 대한 연구

정승민(Seung-Min Chung),배옥남(Ok-Nam Bae),노지윤(Ji-Yoon Noh),김수진(Su-Jin Kim),임경민(Kyung-Min Lim),정진호(Jin-Ho Chung) 한국독성학회 2006 Toxicological Research Vol.22 No.4

Lipid mediator such as lysophosphatidic acid (LPA) plays an important role in inflammation and wound healing, has been recently reported to induce influx of extracellular calcium into erythrocytes. This elevation in intracellular calcium level may cause destruction of membrane asymmetry and procoagulant microvesicle formation. Thus, we investigated if the lipid mediator could induce microvesicle formation as a result of extracellular calcium influx in human erythrocytes. Treatment with lipid mediator to erythrocytes resulted in microvesicle generation in a concentration-, timedependent manner. Microvesicles formed expressed procoagulant phosphatidylserine (PS) on their surface membrane significantly as well. LPA did not affect the band 3 phosphorylation which is involved in morphological change in erythrocytes. Pretreatment with suramin did not inhibit LPAinduced microvesicle generation, suggesting microvesicle generation was not receptor-dependent pathway. Depletion of intracellular ATP levels in erythrocytes was suggested to be one of the mechanism for these events.

어린이 융합형 에듀테인먼트 콘텐츠 Seeing-Sing앱 개발 연구

정승민 ( Seung Min Chung ),홍성욱 ( Sung Wook Hong ),유현정 ( Hyun Jung Yu ) 디자인융복합학회 2014 디자인융복합연구 Vol.13 No.4

본 연구는 디지털 디바이스의 의존도 증가로 인하여, 어린이를 위한 에듀테인먼트 콘텐츠의 요구 또한 늘고 있는 추세에 대응하여, 현재 어린이 앱 시장의 대부분을 차지하는 소모성, 오락성 게임 콘텐츠와 차별화되는 에듀테인먼트 콘텐츠 Seeing-Sing앱을 개발하였다. 증가하는 어린이 시장의 요구에 따라, 다양한 게임과 애니메이션이 등장하고 있지만, 대부분 오락형, 소모성, 수동적 콘텐츠라는 한계를 지적 받기도 하며, 무엇보다 국내에서 연구하고, 개발한 창의형, 능동적 교육콘텐츠는 실질적으로 부족한 실정이다. Seeing-Sing앱은 디지털 디바이스의 활성화로 증가하는 어린이 앱 시장의 요구에 교육적 방향으로 대응하고자, 어린이의 감성을 자극할 수 있는 예술중심의 미술과 음악 융합형 앱 콘텐츠 연구를 시도하였다. 어린이 인지발달연구를 기반으로 융합형 콘텐츠의 방향을 살펴보고자 한다. 오늘날 국내외에서 차세대를 위한 창의적 인재 양성 방안으로 환영받고 있는 융합형 인재 교육은 최근 예술 영역을 추가하여 창의성과 감성을 일깨우는 교육의 방향으로 주목받고 있다. 본 연구는 이에 해당하는 예술영역내의 미술과 음악의 융합적 시도로, 7-11세의 어린이가 놀이를 통해 디자인 사고의 과정을 경험하여, 음악과 미술에 대한 흥미를 자연스럽게 학습으로 유도하게 한다. Seeing-Sing앱의 개발 이후, 여러차례 교육 전문가 집단의 평가 및 피드백을 통해 실질적인 활용 및 연구 보완 방향을 구체적으로 제시하고자 한다. As digital devices have jumped into our ordinary lives, the life ofour kids also became dependent on them. So the demands for kids contents got highly grown and edutainment contents are welcomed. However, the majority of them consist of entertaining, consuming and passive-watching contents such as games and animations. In confronting this kids’ market situation, we’ve developed ‘Seeing-Sing App’ to differentiate contents quality as active, child-leading, and educational for kids. That’s what Seeing-Sing App is different fromothers, leading kids to participate in contents as a thinker. This study is based on the studies of child-cognitive development and education, targeting age 7 to 11 stimulating creativity and integrated thinking. Seeing-Sing App. is try of converged edutainment contents of Music and Arts. This will naturally lead kids to get interested in Art and Music followed by voluntary learning. In this study, therefore we are proposing supplement plan considered by educators, teachers and student class feedback to develop for next study.

갑상선기능항진과 갑상선눈병증의 첫 증상으로서 후천사시와 복시

정승민(Seung Min Chung),김원제(Won Jae Kim) 대한안과학회 2020 대한안과학회지 Vol.61 No.3

목적: 후천사시와 복시가 갑상선눈병증과 갑상선기능항진의 첫 임상증상이었던 환자들의 임상양상을 분석하고자 한다. 대상과 방법: 2017년 1월부터 2018년 12월까지 후천사시와 복시로 내원한 환자들의 의무기록을 후향적으로 분석하였다. 이들 중 복시의 원인감별을 위해 시행한 검사에서 갑상선눈병증과 갑상선기능항진을 진단받은 환자들이 연구에 포함되었다. 결과: 연구기간 동안 410명의 환자가 후천사시와 복시로 안과에 의뢰되었고, 이 중 12명이 연구에 포함되었다(2.9%, 12/410). 복시가 발생한 평균 나이는 54.7년이었다(범위, 18-78년). 이 중 9명(75%, 9/12)이 남성이었다. 6명의 남성이 흡연자였다. 하사시가 가장 흔한 형태의 사시였다(83.3%, 10/12). 평균 하사시각은 17.5PD였다(범위, 4-40PD). 한 명은 외사시와 하사시를 보였고, 1명은 내사시와 양안 상측 운동제한을 보였다. 경과 관찰 중 4명의 남성이 사시수술을 시행 받았으며, 이들은 모두 흡연자였다. 한 명의 여성이 안와감압술을 시행받았다. 결론: 후천사시와 복시로 갑상선눈병증과 갑상선기능항진을 진단받은 경우는 남성에서 더 많았다. 하사시가 가장 흔한 형태의 사시였으며, 흡연하는 남성에서 여성보다 더 심한 임상경과로 진행할 가능성이 많았다. Purpose: We evaluated the clinical characteristics of patients who recently acquired strabismus and diplopia as the initial presentations of hyperthyroidism and thyroid eye disease (TED). Methods: The medical records of patients with acquired strabismus and diplopia who visited our clinic for evaluation between January 2017 and December 2018 were retrospectively reviewed; patients diagnosed initially with hyperthyroidism and TED were included in this study. Results: A total of 410 patients were referred to our clinic for the evaluation and treatment of diplopia. Among these patients, 12(2.9%, 12/410) showed acquired strabismus and diplopia as the initial presentation signs of hyperthyroidism and TED. The mean age of onset of diplopia was 54.7 years (range, 18-78 years). Nine patients (75%, 9/12) were male. Six male patients were active smokers at the initial presentation. Hypotropia was the most common type of strabismus (83.3%, 10/12). The mean angle of hypodeviation was 17.5 prism diopters (PD) (range, 4-40 PD). One patient showed exotropia with hypotropia and one patient showed esotropia with a bilateral up gaze limitation. Four male patients (all active smokers) underwent strabismus surgery, and one female patient underwent orbital decompression surgery. Conclusions: The incidence of acquired strabismus and diplopia as the initial presentation sign of hyperthyroidism was predominant in male patients. Hypotropia was the most common type of strabismus. Male patients who smoked were more likely to show progression to a severe clinical course than female patients.

심부정맥혈전증이 동반된 Churg-Strauss 증후군

정승민 ( Seung Min Chung ),이진희 ( Jin Hee Lee ),전준석 ( Jun Seok Jeon ),조아진 ( A Jin Cho ),정윤진 ( Yun Jin Jeung ),이병재 ( Byeoung Jae Lee ),최동철 ( Dong Chull Choi ),김태은 ( Tae Eun Kim ) 대한천식알레르기학회 2011 천식 및 알레르기 Vol.31 No.2

Churg-Strauss syndrome (CSS) is a rare multi-system vasculitis. Patients with CSS are at greater risk of venous thromboembolic events. However, venous thrombosis is rarely reported in patients with CSS in Korea. We report 1 patient with CSS who experienced deep vein thrombosis. A 27-year-old man was admitted to our hospital due to fever, cough, skin rash on both lower extremities, and right leg edema. He was diagnosed with CSS based on a history of asthma, peripheral eosinophilia, transient pulmonary infiltrates on chest radiograph, and extravascular eosinophils in the skin biopsy specimens. After steroid pulse therapy and the first cycle of intravenous pulse cyclophosphamide therapy, right leg edema did not resolve. Venous ultrasonography and CT angiography detected deep vein thrombosis involving the right common iliac, femoral and calf veins. The patient received both anticoagulation therapy and intravenous pulse cyclophosphamide therapy. After 6 months of anticoagulation therapy and the 9 cycles of intravenous pulse cyclophosphamide therapy, deep vein thrombosis completely resolved. (Korean J Asthma Allergy Clin Immunol 2011;31:148-152)

경량, 고강도 복합재연소관 제조용 핫멜트 타입 토우 프리프레그 개발의 기본요구조건 연구

정상기(Sang Ki Chung),황태경(Tae Kyeong Hwang),정승민(Seung Min Jeong),송하율(Ha Yool Song),우종인(Jong In Woo),김현진(Hyun Jin Kim),장기욱(Key Wook Jang) 한국추진공학회 2019 한국추진공학회 학술대회논문집 Vol.2019 No.5

미용 산업에 있어서 접점 종업원의 조직시민행위에 관한 이론적 고찰

박선주(Park Sun-Ju),정승민(Chung Seung-Min) 한국인체미용예술학회 2005 한국인체미용예술학회지 Vol.6 No.2

  In order to make service business successful, the attitude of MOT employees who make firsthand contact with customers is crucial, as consumer evaluation relies on that. Internal marketing that stresses efficient MOT personnel management and education is one of the decisive factors to determine the success or failure of business. Existing studies have mostly concentrated their attention on the impacts of organizational citizenship behavior among customer contact employees on customer attitude, including satisfaction and repurchase intention, profitability and the effect of words of mouth. But the purpose of this study was to put stress on the importance of MOT employees in service industry and their systematic management, and to delve into their job satisfaction and job adjustment as parameters to stimulate their spontaneous organizational citizenship behavior. And it"s additionally attempted to identify what sorts of variables could positively affect the parameters to provide firsthand motivation to them.

메나디온에 의한 혈소판 내 칼슘 변화측정시 형광 색소 사용의 문제점

정선화(Sun Hwa Chung),이무열(Moo Yeol Lee),이주영(Joo Young Lee),정승민(Seung Min Chung),정진호(Jin Ho Chung) 대한약학회 1997 약학회지 Vol.41 No.6

It has been reported that dose-dependent Ca2+ increase by menadione in platelets could be measured by fluorescent dye, quin-2. The problems will be described here relating to measuring Ca2+ in menadione-exposed platelets using fura-2 and fluo-3, widely used fluorescent indicators. Additions of menadione to fura-2 loaded platelets and their lysates resulted in marked reduction in fluorescence intensity at both 340nm (Ca2+-unbound form) excitation wavelengths. Fura-2 excitation spectra were overlapped with UV-visible absorption spectra of menadione, suggesting that light absorption by menadione itself could quench fluorescence generated by fura-2. Next approach was to use fluo-3 which has the higher wavelength (490nm) of excitation. Previous work demonstrated that treatment with probenecid to platelets was required to prevent fluo-3 dye leakage. However, probenecid itself was proven to be inadequate to measure the concentration of intracellular Ca2+ by reducing menadione-induced cytotoxicity in platelets. Our results suggest that it is not feasible to measure Ca2+ in platelets by using fura-2 and fluo-3 in the presence of probenecid, and cautions should be taken to measure changes of intracellular Ca2+ levels by fluorescent dyes following chemical exposure.

증례 : 소화기 ; 위장관 출혈을 동반한 맥켈 게실 내 이소성 췌장 1예

이진희 ( Jin Hee Lee ),민병훈 ( Byung Hoon Min ),이준행 ( Jun Haeng Lee ),전준석 ( Jun Seok Jeon ),정승민 ( Seung Min Chung ),정병호 ( Byeong Ho Jeong ),김경미 ( Kyoung Mee Kim ) 대한내과학회 2011 대한내과학회지 Vol.81 No.4

저자들은 반복적인 다량의 혈변을 주소로 내원한 29세 여자 환자에서 출혈의 원인이 되었던 멕켈 게실 내 이소성 췌장을 경험하였기에 문헌고찰과 함께 보고하는 바이다. Heterotopic pancreas is a tissue histologically similar to normal pancreatic tissue found in a location other than the usual place, and having no anatomic or vascular connection with the pancreas itself. Heterotopic pancreas is usually asymptomatic and found incidentally. However, it can cause problems such as abdominal pain, melena, anemia, and severe bleeding. We report a case of a 29-year-old woman with obscure gastrointestinal bleeding caused by heterotopic pancreas located in Meckel`s diverticulum. Gastroduodenoscopy and colonoscopy showed no bleeding focus. By capsule endoscopy and double balloon enteroscopy, a bleeding focus was suspected in the ileum. The patient received a laparoscopic resection of the Meckel`s diverticulum. Pathologic examination revealed heterotopic pancreatic tissue within the muscular layer of the diverticulum. The patient recovered well without further bleeding. (Korean J Med 2011;81:492-495)

무증상 원발성 막성 신병증에 병발한 반월상 사구체 신염 1례

조아진 ( A Jin Cho ),이진희 ( Jin Hee Lee ),정병호 ( Byeong Ho Jeong ),정승민 ( Seung Min Chung ),이정은 ( Jung Eun Lee ),권기영 ( Gee Young Kwon ),허우성 ( Woo Seong Huh ),김윤구 ( Yoon Goo Kim ),김대중 ( Dae Joong Kim ),오하영 ( 대한신장학회 2010 Kidney Research and Clinical Practice Vol.29 No.2

Membranous glomerulopathy (MGN) is a common cause of nephrotic syndrome in adults. Renal failure gradually develops in patients with MGN and crescentic glomerulonephritis (CGN) superimposed on MGN is a rare cause of acute renal failure. In most cases patients showed nephrotic syndrome with acute renal failure. We report a 33-year-old woman with azotemia but with no other symptoms such as nephrotic syndrome she had been diagnosed to have MGN 15 months before. There seemed to be no other cause of azotemia. Renal biopsy was performed and revealed CGN on existing MGN. She was treated with immunosuppression treatment and azotemia was improved. When unexplained azotemia develops in patients with MGN, we should promptly investigate superimposed conditions including CGN. In CGN superimposed on MN, a potentially reversible condition with appropriate immunosuppression therapy should be considered.