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두개강내 내배엽성 동종양(Endodermal Sinus Tumor)
임용철,조경기,이성운,박한준,신용삼,윤수한,조기홍,Lim, Yong Chull,Cho, Kyung Gi,Lee, Seong Un,Park, Han Jun,Shin, Yong Sam,Yun, Soo Han,Cho, Ki Hong 대한신경외과학회 2001 Journal of Korean neurosurgical society Vol.30 No.12
Objective : Endodermal sinus tumor or yolk sac tumor is an uncommon malignant germ-cell neoplasm. This tumor was originally described as a germ cell tumor of the ovary or the testis. Intracranial endodermal sinus tumor is extremely rare and usually develop in the pineal or suprasellar regions. The authors evaluated the effect of adjuvant therapy(chemotherapy combined with radiotherapy) and radical removal of intracranial endodermal sinus tumors. Material and Methods : Between 1996 and 2001, four patients of intracranial endodermal sinus tumor were diagnosed with tumor marker(AFP) and biopsy. Three patients were treated with surgical removal and chemotherapy with cisplatin($20mg/m^2$), etoposide($100mg/m^2$) and bleomycin($15mg/m^2$) as well as external beam radiation therapy. We compared the management problems for these tumors. Result : In all three patients the tumor size and the level of tumor marker decresed during initial adjuvant therapy. However, Tumors showed regrowth with elevated AFP of serum and CSF possibly related to delayed chemotherapeutic treatment or inadequate administration of chemotherapeutic drugs due to severe bone marrow suppression. An additional chemotherapy and external radiation therapy were given, but tumors could not be controlled with leptomeningeal seeding. Conclusion : Radiotherapy is considered to be less effective. The combination chemotherapy with PVB(cisplatin, vinblastine, bleomycine) or PE(cisplatin, etoposide) is considered to be value in prolongation of the survival rate. But the role of chemotherapy in this tumor has not yet been clarified due to bone marrow suppression and drug resistance. Further study with large series of this tumor is necessary to establish the optimal management.
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치아표면 처리방법과 thernocycling이 콤포짓트 레진 코어의 미세누출에 미치는 영향
임용철,진태호,Lim, Yong-Chul,Jin, Tai-Ho 대한치과보철학회 2000 대한치과보철학회지 Vol.38 No.2
The purpose of this study was to compare the microleakage of the composite resin cores according to surface treatment, dentin bonding agents, and thermocycling. For this study, 120 extracted premolar teeth were used. Flat occlusal surfaces were prepared with diamond disk, and treated with air-abrasion, acid-etching, combination. The composite resin core was built with Z-100 after application of Scotchbond Multi-Purpose and All-Bond 2. Prepared specimens were thermocycled for 2,000 cycles. Specimens were immersed in 1% methylene blue solution for 24hours at $37^{\circ}C$. The microleakage was measured with a inverted metallurgical microscope(BHS313, Olympus, Japan). The following conclusions were drawn from this study: 1. The microleakages in the groups treated with air-abrasion and with acid etching were greater than that of the groups treated with combination method before thermocycling(p<0.05), the microleakages of the groups treated with air-abrasion were greater than that of the groups treated with acid-etching and combination method after thermocycling(p<0.05) 2. There were no significant difference between groups using Scotchbond Multi-Purpose and the groups using All-Bond 2. 3. Thermocycling didn't affect the change of microleakage in all cases.
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터키안 및 주변 해면정맥동, 사골동, 접형동에 발생한 용종성 혈관내피 과증식증- 증 례 보 고 -
임용철,조경기,안영민,윤수한,조기홍,심철 대한신경외과학회 2002 Journal of Korean neurosurgical society Vol.31 No.1
Papillary endothelial hyperplasia(PEH), usually originates in extracranial soft tissue, is considered a reactive proliferation of endothlium and an unusual form of thrombus organization. However the occurance of PEH in the cranial cavity is very rare. The authors report a case of a PEH involving intracranial sella, parasella, cavernous sius, ethmoid and sphenoid sinus in an 11-year-old boy. The patient was presented with sudden right visual disturbance. Magnetic resonance image showed a well-enhanced mass in the right cavernous sinus extending into the ethmoid and sphenoid sinus. The cerebral angiography demonstrated a vigorous tumor staining supplied by both internal and external carotid arteries. The right fronto-temporal craniotomy and subtotal resection of the tumor were performed. The mass was comprised in a highly vascular red-black nodular tissue associated with a mixture of fresh and organizing thrombi. The histopathological examination revealed papillary structures lined by endothelium within vascular space with organized thrombus. While the patient was waiting for second operation in order to remove remaining small tumor in the ethmoid and sphenoid sinues, the lesion exhibited rapid regrowth and the size became to the preoperative size at three months after operation. At reoperation, gross total removal was accomplished by a combination of trans-cranial and trans-sphenoidal approaches. Postoperative radiotherapy was given. Key words:Papillary endothelial hyperplasia;Intracranial;Gross total removal;Radiotherapy.
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치아표면 처리방법과 thermocycling이 콤포짓트 레진 코어의 미세누출에 미치는 영향
임용철,진태호 원광대학교 치의학연구소 1999 圓光齒醫學 Vol.9 No.2
The purpose of this study was to compare the microleakage of the composite resin cores according to surface treatment, dentin bonding agents, and thermocycling. For this study, 120 extracted premolar teeth were used. Flat occlusal surfaces were prepared with diamond disk, and treated with air-abrasion, acid-etching, combination. The composite resin core was built with Z-100 after application of Scotchbond Multi-Purpose and All-Bond 2. Prepared specimens were thermocycled for 2,000 cycles. Specimens were immersed in 1% methylene blue solution for 24 hours at 37'C. The microleakage was measured with a inverted metallurgical microscope(BHS313, Olympus, Japan). The following conclusions were drawn from this study: 1. The microleakages in the groups treated with air-abrasion and with acid-etching were greater than that of the groups treated with combination method before thermocycling(p<0.05), the microleakages of the groups treated with air-abrasion were greater than that of the groups treated with acid-etching and combination method after thermocycling(p<0.05). 2. There were no significant difference between groups using Scotchbond Multi-Purpose and the groups using All-Bond 2. 3. Thermocycling didn't affect the change of microleakage in all cases.
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임용철,정준호,김창현,김용배,주진양,신용삼 연세대학교의과대학 2015 Yonsei medical journal Vol.56 No.2
Purpose: The purpose was to evaluate the incidence and risk factors for rebleeding during cerebral angiography in ruptured intracranial aneurysms. Materials and Methods: Among 1896 patients with ruptured intracranial aneurysms between September2006 and December 2013, a total of 11 patients who experienced rebleeding of the ruptured aneurysms during digital subtraction angiography (DSA) were recruitedin this study. Results: There were 184 patients (9.7%) who had suffered rebleedingprior to the securing procedure. Among them, 11 patients experienced rebleedingduring DSA and other 173 patients at a time other than DSA. Eight (72.7%) of the 11 patients experienced rebleeding during three-dimensional rotationalangiography (3DRA). The incidence of rebleeding during DSA was 0.6% in patients with ruptured intracranial aneurysms. Multivariate logistic regression analysisshowed that aneurysm location in anterior circulation [odds ratio=14.286; 95% confidence interval (CI), 1.877 to 250.0; p=0.048] and higher aspect ratio (odds ratio=3.040; 95% CI, 1.896 to 10.309; p=0.041) remained independent risk factors for rebleeding during DSA. Conclusion: Ruptured aneurysms located in anterior circulationwith a high aspect ratio might have the risk of rebleeding during DSA, especiallyduring 3DRA.
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임용철 고려대학교 정보창의교육연구소 2010 정보창의교육논문지 Vol.4 No.2
빠르게 변화하는 시대 흐름에 따라 많은 스마트폰들이 출시되면서 스마트본의 시대가 되었다. 현재 스마트폰에서 사용되는 OS는 크게 Windows Mobile, Android기반, iOS, Symbian등이 있다. 스마트폰의 시장이 거대해 짐에 따라 이러한 OS들을 기반으로 한 어플리케이션들이 많이 개발되었다. 스마트 폰에서 주목 받는 기능 중 하나는 GPS이다. 현재 네비게이션 기기를 사용하여 길을 찾는 것은 보편화된 운전기술문화이다. 그러나 GPS기능을 갖춘 스마트폰이 보급되면서 네비게이션 없이도 길 찾기 기능을 사용할 수 있다. 이 때문에 스마트폰이 더욱 널리 보급되고 있다. 예전에는 GPS를 활용하여 길 찾기가 주된 관심사였지만 현재는 주변 시설이나 음식점 찾기 또는 사람 찾기 등 많은 분야로 확장되고 있다. 현재 이와 유사한 어플리케이션이 Windows Mobile OS기반으로는 개발되지 않았다. 본 논문에서는 Windows Mobile OS를 기반으로 근거리에 있는 친구를 찾는 어플리케이션을 개발하였다.
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양수막을 통한 수분유출 기간 중 Li 이동에 미치는 항이뇨호르몬 및 Prolaction의 영향
임용철 ( Yong Chul Lim ),최석태 ( Seok Tae Choi ),박노현 ( Noh Hyun Park ),신희철 ( Hee Chul Syn ),성호경 ( Ho Kyung Sung ) 대한산부인과학회 1997 Obstetrics & Gynecology Science Vol.40 No.12
In order to investigate the effects of vasopressin and prolactin on the regulation of amniotic fluid volume and sodium concentration in pregnant rabbits, lithium transport as an index of sodium transport and amniotic fluid volume regulation through amniotic membrane was studied. Pregant rabbits were anaesthetised with pentobarbital (30mg/kg) and exposed uterus. To exclude possible contamination of residual hormone in amniotic fluid, 70 % of amniotic volume were replaced by isotonic saline. Isotonic saline (0.5ml) containing 0.5mg of congo red and 15mM of LiCl was injected into each amniotic sac. Amniotic fluid samples were taken in 30 and 60 minutes after saline injection and measured Na+, Li+ and congo red concen1rations. Only the amniotic samples which showed the decrease in congo red concentration after 30 or 60 minutes were chosen to analyse in this study. Vasopressin (25ng) or prolactin (1mg) was injected into experimental amniotic sacs and measuerd Na+, Li+, congo red and amniotic fluid volume as in control group. Then the rate of water efflux, Li-and Na-influx and efflux were ana1ysed and compared. The results were obtained as follows; 1) The efflux ratio of Na+ to water in amniotic fluid was relatively constant (about 95 %) in control, which was independent from the magnitude of water efflux rate. The efflux ratio of lithium to water, however, increased from 20 % with the increase of the magnitude of water efflux. 2) In vasopressin injected group, the water efflux rate was decreased than in control group and the efflux ratio of Na+ to water was not consistent (sometimes decreased or increased). On the other hand the efflux ratio of Li+ to water was in the same range as in control when the water efflux rate was in the range of control value, however, it profoundly increased when the water efflux rate was below 10%. 3) In prolactin treated group, the water efflux rate was very high when the initial Na+ concentration was low. The influx or efflux of Li+ was very large independently from the magnitude of water efflux rate or from initial Na+ concentration probably due to vigorous diffusion. From the above results, it is suggested that vasopressin inhibit the increase of the amniotic fluid volume during fetal urination and maintain Na+ concentration of the amniotic fluid not through the direct effect on the amniotic membrane, but thorugh the effect on fetal kidney. On the other hand, prolactin regulates Na+ concentration of the amniotic fluid very rapidly by the increase of diffusion of monovalent cations through the amniotic membrane.
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