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Preparation of multi-component ceramic proton conductors for intermediate temperature fuel cell
임병무(Lim, Byeong-mu),서동호(Seo, Dong-ho),박상선(Park, Sang-sun),이홍연(Lee, Hong-yeon),설용건(Shul, Yong-Gun) 한국신재생에너지학회 2009 한국신재생에너지학회 학술대회논문집 Vol.2009 No.06
The multi-component ceramic proton conductor, BaZr(Y)O₃-SiO₂-TiO₂-ZrO₂ (BZY-STZ) and LaPO₄-SiO₂-TiO₂-ZrO₂ (LP-STZ), were synthesized by micro-emersion and sol-gel technique. The characterization of proton conductors were carried out using X-ray diffraction(XRD), thermogravimetric analysis(TGA), differential thermal analysis(DTA), impedance analysis. The proton conductors indicate the possibility of application for the intermediate temperature up to 700?C.
The current status of fumonisin toxicosis in domestic animals: A review
임채웅,임병무,Lim, Chae-woong,Rim, Byung-moo The Korean Society of Veterinary Science 1995 大韓獸醫學會誌 Vol.35 No.2
말의 뇌화연증(equine leukoencephalomalacia)과 돼지의 폐수종(porcine pulmonary edema)은 Fusarium에 오염된 옥수수로 인하여 발생되는 것으로 추정되어 왔다. 1988년에 F moniliforme에서 2차 대사산물인 fumonisin $B_1(FB_1)$이 동정되면서 오염된 옥수수와 순수 분리된 $FB_1$으로 두질병이 실험적으로 재현되었고, 말과 돼지 이외의 다른 가축에 대해서도 독성 연구가 진행되고 있다. fumonisins(FBs)는 모든 종에서 간에 독성을 나타내나 종에 따라 주요 독성 장기가 각기 다름이 밝혀지고 있다. FB의 독성 기전에 대해서는 잘 알려지지 않았으나 FB가 sphingolipid 생성과정을 차단함으로써 장기 및 혈중에 sphinganine(SA) : sphingosine(SO)를 증가시키는 것으로 알려졌다. 이는 증가된 SA : SO가 FB 독성의 진단기준이 될 수 있음을 시사하는 것이다. 최근 진행 중인 연구에 의하면, 저용량의 $FB_1$ 급식 투여가 돼지에서 혈중 입자(blood-born particle)에 대한 폐혈관 대식 세포(pulmonary intravascular macrophage)의 탐식 능력을 저하시켜, 세균 감염에 대한 감수성이 증가될 수 있음을 시사하고 있다. Fusarium 속균은 전세계적으로 생산되는 옥수수에서 발생되고 있으며, 우리나라는 사료에 사용되는 옥수수의 절대량을 수입에 의존하고 있는 점을 고려할 때, 허용기준 및 무해용량 등에 대한 관리가 절실하다. 이 논문에서는 최근 연구된 FB에 의한 가축 독성에 대하여 기술하고자 한다. FBs, secondary metabolites of several species of Fusaria, especially Fusarium moniliforme and F proliferatum, are commonly contaminated in com and other food grains throughout the world. Only recently identified, these mycotoxins have been associated field outbreaks of ELEM in horses and PPE in pigs. Currently, naturally or experimentally induced FB toxicosis has been studied in poultry, ruminants and rabbits. Poultry fed FB showed decreased growth rate, performance, and immune competence, as well as embryopathic, and embryocidal effects, and ricktes. Ruminants seem to be relatively less susceptible to FBs than other doestic animal. FB toxicosis reveals that liver is a target organ in all species, although other organs are affected in a species specific manner. Recently, the main target organs for $FB_1$ toxicity in rabbits was shown to be the kidney. Even low concentrations of FBs are likely to be a problem for animal health. A current study being conducted showed that feed containing low level of $FB_1$ reduces the ability of pulmonary intravascular macrophages in pig to clear blood-borne particles which would increase the susceptibility of animals to bacterial disease. The mechanism of FB toxicity remains unknown, but may be related to altered sphingolipid biosynthesis by inhibiting sphinganine N-acyltransferase. Elevations of serum and tissue SA:SO ratio have been observed in horse, pig, chicken, turkey, and rabbit, which could could serve as in effective biomarker for consumption of FB-containing feeds. There is limited information detailing dose-effect relationships either from field cases or in the laboratory. More research on the factors, including the prevalence and tolerance levels of FBs in feedstuffs that cause domestic animal disease associated with FBs, is urgently needed.
청소년의 여가활동 참여가 여가만족 및 학교생활적응에 미치는 영향
김창현(Kim, Chang-Hyun),임병무(Lim, Byung-Mu),최윤동(Choi, Youn-Dong),이상진(Lee, Sang-Jin) 한국체육과학회 2015 한국체육과학회지 Vol.24 No.5
The purpose of this study was to examine the influence of the leisure participation of on their leisure satisfaction and school adjustment. The subjects in this study were 358 students at a middle school located in Gyeonggi Province, on whom a self- administered survey was conducted. The collected data were analyzed by the statistical package SPSS WIN 18.0. Statistical data on mean and standard deviation were obtained, and t-test and one-way ANOVA were utilized. Besides, Duncan test was carried out to make a post-hoc analysis. The findings of the study were as follows: First, as for differences in leisure satisfaction according to personal characteristics, there were significant intergroup differences according to both of gender and grade. Second, concerning differences in school adjustment according to personal characteristics, there were significant intergroup differences according to both of gender and grade as well. Third, regarding differences in leisure satisfaction according to the level of participation, there were statistically significant differences at p<.001 level of significance according to the experience, frequency and hours of participation. Fourth, as to differences in school adjustment according to the level of participation, there were statistically significant differences at the p<.001 level of significance according to the experience, frequency and hours of participation.
정신건강의학과 자문 의뢰된 암 환자의 항우울제 내약성 비교 연구
고은미,박진성,하주원,임세원,김태석,하지현,백종우,이병철,최병무,이강준,김성완,양종철,고영훈,오강섭,Ko, Eunmi,Park, Jin-Seong,Ha, Juwon,Lim, Sewon,Kim, Tae-Suk,Ha, Jee Hyun,Paik, Jong-Woo,Lee, Boung Chul,Choe, Byeong Moo,Lee, Kang-Joon,Kim, Sun 한국정신신체의학회 2013 정신신체의학 Vol.21 No.1
연구목적 암환자들은 다양한 정신건강의학과적 증상을 겪으며 약물 부작용에 취약하다. 본 연구는 정신건강의학과 자문 의뢰된 암환자에서 항우울제의 내약성을 비교하고자 한다. 방 법 9개 대학병원 및 종합병원 정신건강의학과에 자문 의뢰된 암 환자들을 후향적으로 검토하여 자료를 분석하였다. 가장 빈번하게 처방된 세가지 항우울제(Escitalopram, Mirtazapine, Paroxetine)의 6개월 동안 치료 중단율을 비교하였다. 결 과 처방 빈도는 Escitalopram 150(47.2%), Mirtazapine 92(28.9%), Paroxetine 76(23.9%) 순서로 항우울제 투여 중단 비율은 세군 간 유의한 차이가 없었다. 입원 환자에 비해 외래 환자에서 유의하게 약물 중단 위험도가 높았다(p<0.0001). 결 론 임상 현장에서 암환자의 항우울제 치료 중단율은 약물 종류에 따라 차이가 없었다. 치료 순응도 향상을 위하여 암환자의 특성을 고려한 개별 접근이 필요할 것이다. Objectives : Many patients diagnosed with cancer suffer from various psychiatric symptoms such as depression, anxiety and insomnia as well as cancer itself. Patients with cancer are more vulnerable to possible adverse events of psychotropic medications. Although antidepressants are widely used among cancer patients, there is little information about tolerability of antidepressants. This study was conducted to compare tolerability of antidepressants in cancer patients referred for psychiatric consultation. Methods : The participants were cancer patients who had been referred to psychiatrist for their psychiatric symptoms. We retrospectively analyzed the data of patients diagnosed with cancer from 9 general hospitals in Korea. The discontinuation rate for a 6 months period after treatment initiation for three antidepressants(Escitalopram, Mirtazapine, Paroxetine) were compared. Results : Antidepressants were prescribed for 96.3% of subjects and Escitalopram 150(47.2%), Mirtazapine 92(28.9%) and Paroxetine 76(23.9%) were prescribed frequently in order There were no significant differences in discontinuation rates among the three antidepressants during the 6 month period after initiation of pharmacotherapy. But there was a difference in discontinuation rates between inpatients versus outpatients(p<0.0001). Conclusions : In a naturalistic setting for the antidepressant treatment for cancer patients, it seems that there are no differences in discontinuation rates among these three antidepressants. It is therefore essential that such interactions are carefully considered when treating patients of antidepressants who already have cancer.
청둥오리에서 Riemerella anatipestifer 감염 증례
이성효 ( Seong Hyo Lee ),임채웅 ( Chae Woong Lim ),서석열 ( Surk Yul Seo ),도홍기 ( Hong Ki Do ),노수일 ( Soo Il Roh ),이호일 ( Ho Il Lee ),임병무 ( Byung Moo Rim ) 한국가축위생학회 1999 韓國家畜衛生學會誌 Vol.22 No.3
Riemerella anatipestifer (RA) infection is a contagious disease of domestic ducks, turkey, and various other birds. In a flock of mallard ducklings, about 30% of the birds, 3 weeks old, showed lethergy, greenish diarrhea, tremor of head and neck, and died 2-3 days after signs appeared. Grossly, fibrinous exudates covered the heart and surface of the live. Microscopically, mononuclear cells and heterophils were primarily inflammatory cells in the exudate. These were also observed in the meninges in brain. Microbiologically, gram (-) short rod bipolar shaped bacteria were recovered on blood agar and agglutinated by antisera of R anatipestifer. Sulfamethoxasole/trimethoprim were administered and clinically effective. This case was a R anatipestifer infection caused fibrinous pericarditis, hepatitis and meningitis in mallards.
IBDV (SH/92)의 인공감염에 의한 닭 면역장기의 병리조직학적 연구
엄성심 ( Sung Shim Eum ),김범석 ( Bum Seok Kim ),임채웅 ( Chae Woong Lim ),임병무 ( Byung Moo Rim ),이호일 ( Ho Il Lee ),정동석 ( Dong Suk Chung ) 한국가축위생학회 1999 韓國家畜衛生學會誌 Vol.22 No.3
Sequential morphologic changes in the lymphoid organs were examined after ocular and cloacal inoculation in 3weekold chicks with a highly virulent strain (SH/92) of infectious bursal disease virus (IBDV). The infected chickens were sacrificed at 6, 12, 24, 48, 72, and 96 hrs post inoculation (P1), and thymus, harderian gland, ceacal tonsil, and spleen were observed. Histologically, the significant lesions were characterized by lymphocyte depletion and the earliest detectable changes were evident at 12 hrs PI. In thymic cortex, lymphoid depletion with apoptosis and prominent "tingible body macrophages" were observed. As the infection advanced, the lesions showed more severe changes. Dying cells were characterized either by capping of nuclear chromatin (apoptosis) or by cytoplasmic swelling (necrosis). In situ staining for apoptosis, some lymphoid cells revealed typical positive reaction, even the stainability was variable depend on every lymphoid organs. These results suggest that IBDV (SH/92) cause severe damage both primary and secondary lymphoid organs, and both T and B lymphocytes. Also the lymphoid depletion of these organs is caused by necrosis and apoptosis induced by IBDV.
노영선 ( Young Sun Roh ),윤여백 ( Yea Baek Yoon ),김영진 ( Yong Jin Kim ),이성희 ( Seong Hee Rhee ),레브코로지스키 ( Lev Kolodzieyski ),임병무 ( Byung Moo Rim ),임채웅 ( Chae Woong Lim ) 한국가축위생학회 2001 韓國家畜衛生學會誌 Vol.24 No.2
To examine the prevalence and types of kidney lesions In Korean cattle, a survey was carried out at a abattoir in September 2000 and January 2001. The collected kidneys were examined grossly and histopathologically and investigated for the patterns of renal diseases with considering season and sex. Of 735 cattle (99 bulls and 246 cows in September and 140 bulls, 3 steers, and 247 cows in January) surveyed, 301 (41%) cattle had various renal lesions. The most common prominent finding was focal or multiple interstitial nephritis (36.2%). Other lesions included focal or multiple renal cyst (9.1%), infarction <0.1%), hemorrhage (0.3%), and renal atrophy (0.3%). Microscopically, main pathological lesions were acute or chronic interstitial nephritis with moderate infiltration of neutrophil or lymphocyte, respectively. Finally, the kidney lesions are more or less correlated with the meat quality, especially in female Korean cattle.
토끼 간콕시듐(Eimeria stiedae) 감염 증례
한재철 ( Jae Cheol Han ),한규삼 ( Kyu Sam Han ),이성희 ( Sung Hee Rhee ),마쓰다기꾸 ( Kiku Matuda ),임병무 ( Byung Moo Rim ),임채웅 ( Chae Woong Lim ) 한국가축위생학회 2001 韓國家畜衛生學會誌 Vol.24 No.1
Hepatic coccidiosis was occurred in a rabbit farm in Chonbuk province. Clinically, rabbits showed anorexia, diarrhea, dehydration, and depression, subsequently died 3-5 days after onset of clinical signs. Grossly, multifocal white spots or lines on the liver surface were observed. Histopathologic lesions included hyperplasia of bile duct epithelium with infiltration of inflammatory cells such as plasma cells and granulocytes, which represents chronic pericholangitis. Different developmental stages of Eimeria stiedae were observed inside the epithelium of biliary system. This is the case of hepatic coccidiosis in rabbits.