A Case of Patent Ductus Arteriosus with Congestive Heart Failure in a 80-Year-Old Man

이혜연,Sung Ho Her,Mahn Won Park,Min Seok Choi,Jung Sun Cho,김찬준,Hye Seon Kang,Yoo-A Choi,Il Nam Ju,Seon A Kim,Jong-Ho Lee,Jong-Bum Kwon,Kuhn Park 대한심장학회 2012 Korean Circulation Journal Vol.42 No.12

Patent ductus arteriosus (PDA) is a rare clinical finding in adult patients. Considering the increase in cases of PDA discovered incidentally on echocardiograms at young ages, and the life-shortening effect of PDA, it is rare to diagnose PDA in old patients. We report a case of an 80-year-old patient who experienced symptoms of congestive heart failure showed findings suggestive of PDA in echocardiogram and confirmed the diagnosis through a cardiac catheterization and a coronary angiography. After percutaneous occlusion of PDA with an Amp -latzer duct occlusion device, symptoms related to congestive heart failure improved.

순창 운림리 농소고분 출토 목관 칠 분석을 통한 제작방법 연구

이혜연,Lee, Hye Youn 한국문화재보존과학회 2017 보존과학회지 Vol.33 No.5

순창 농소고분은 적성면 운림리 일대와 내월리 농소마을을 둘러 형성된 구릉지 능선에 위치하고 있다. 고분의 토광은 비교적 깊은 곳에 조성되어 도굴의 피해가 없었으며 전체적으로 다량의 숯으로 채워져 있어 목관이 비교적 좋은 상태로 출토되었다. 고분 구조 및 매장시설, 출토 유물, 방사선탄소연대 측정 결과를 종합하였을 때 농소 고분의 축조시기는 고려시대 후기부터 조선 초기까지로 추정하고 있다. 농소고분에서 출토된 목관은 목곽과 목관의 2중 구조로 목관 외면에 두껍게 옻칠을 하고 금색 문자와 흰색 문양으로 장식되었다. 안료 분석 결과 금색 문자는 금(Au), 흰색 문양은 은(Ag)이 주요 성분으로 확인되었다. 칠 막은 안료 층, 황갈색 층, 검은 층의 3개 층으로 관찰되었다. 검은 층은 그을음과 같은 검은 물질로 목재 바탕의 밑칠로 사용되었다. 황갈색 층은 옻칠로서 정제칠로 추정된다. 목관 칠막 분석을 종합하면 칠 제작방법은 금박을 이용하는 방법과 금분을 이용하는 방법으로 추정된다. 안료 형태 및 내부 구조상으로는 금박이 유력하지만 표현된 글자의 형태를 보면 금분을 이용한 것으로 보인다. 따라서 향후 금박과 금분을 이용한 재현실험을 통하여 제작방법을 확인한다면 고분 축조 당시 칠기 제작기술을 파악하는데 중요한 자료가 될 것이다. The Nongso tomb of Sunchang was built in a relatively deep place; hence there was little damage from grave robbers. The tomb was completely filled with a large amount of charcoal, and therefore the wooden coffin was excavated in relatively good condition. On the basis of the structure of the tombs, excavated artifacts, and radiocarbon dating results, the tomb is estimated to be from between the late Goryeo and the early Joseon period. The wooden coffin excavated is double-layered structures consisting of an outer coffin and an inner coffin. The outside of the wooden coffin is thickly lacquered and decorated with yellow letters and white motifs. An analysis of the pigments' components revealed that the major component of the letters was gold (Au) and the major component of the motifs was silver (Ag). The coffin lacquer had three layers: a pigment layer, a yellowish-brown layer, and a black layer. The wooden bases of the coffins were painted with a black substance, such as soot, as mineral elements were not detected in the black layer. The yellowish-brown layer is presumed to be refined lacquer. From the analysis of the structure of the layers and pigments, we can estimate the method was adopted for making lacquer for wooden coffin. It is assumed that the method used gold leaf and gold powder. The form of the pigment and the internal structure are likely to be gold leaf, but the shape of the surface letters appears to have been formed using gold powder. This study will serve as important information for understanding lacquer making techniques at the time of the tombs' construction by confirming the making method through reproduction experiments using gold leaf and gold powder.

저선량 γ선 조사가 고추의 광합성과 광 스트레스 경감에 미치는 효과

이혜연,백명화,박순철,박연일,김재성,Lee, Hae-Youn,Baek, Myung-Hwa,Park, Soon-Chul,Park, Youn-Il,Kim, Jae-Sung 한국환경농학회 2002 한국환경농학회지 Vol.21 No.2

고추 종자에 저선량 $\gamma$선을 조사시킨 고추 식물체의 생육과 광합성 능 및 광 스트레스 반응에 미치는 영향을 조사하였다. 저선량 4 Gy가 조사된 고추 식물체에서 광합성에 의한 산소발생이 대조구에 비해 1.5배정도 높은 것으로 나타났다. 고추 잎에 900 ${\mu}mol/m^2/s$의 빛의 세기로 광저해를 4시간 유도하였을 때 최대 광합성능 (Pmax)이 대조구의 경우 20%정도 감소되는 반면 4 Gy 조사구는 3% 정도의 감소를 보였다. Fv/Fm는 광저해가 진행됨에 따라 감소되는 경향을 보이며 대조구의 경우 4시간 처리시 Fv/Fm 값이 50% 정도 감소되는 것을 볼 수 있었다. 반면 4 Gy 조사구는 Fv/Fm값이 대략 37%정도 감소되어 대조구에 비해 광 스트레스에 대해 덜 민감한 것으로 나타났다. Fo는 광저해가 진행됨에 따라 거의 변화가 없었으며 대조구나 4 Gy조사구 사이의 차이도 거의 없는 것으로 나타났다. 광계II의 광양자 수율인 $\Phi_{PSII}$과 광계II 반응중심에 의한 여기 포획률을 나타내주는 1/Fo-1/Fm 또한 광저해가 진행됨에 따라 감소되었으며 4시간을 처리했을 경우 각각 대조구는 47%, 4 Gy 조사구는 30%의 감소를 볼 수 있었다. 비광화학적 소멸인 NPQ는 광저해가 진행됨에 따라 감소되는 경향을 보였으나 대조구와 4 Gy 조사구간에 차이는 없는 것으로 나타났다. 이러한 결과를 볼 때 종자의 종피를 투과한 저선량의 $\gamma$선이 식물의 광합성을 증대시키고 동시에 광 스트레스에 대한 저해를 감소시키는 것으로 보인다. The effect of low dose $\gamma$ radiation on photosynthesis and the reduction of photoinhibition in red pepper plant was investigated. The seedling height leaf width and leaf length of pepper were stimulated in plants grown from seeds irradiated with the low dose of 4 Gy. The $O_2$ evolution in the 4 Gy irradiation group was 1.5 times greater than in the control. To investigate the effect of low dose $\gamma$ radiation on response to high light stress, photoinhibition was induced in leaves of pepper by illumination of high light (900 $\mu mol/m^2/s$). Pmax was decreased with increasing illumination time by 20% in the control, while hardly decreased in the 4 Gy irradiation group. The photochemical yield of PSII, estimated as Fv/Fm, was decreased with increasing illumination time by 50% after 4 hours while Fo did not change. However, Fv/Fm in the 4 Gy irradiation group was decreased by 37% of inhibition, indicating that the photoinhibition was decreased by the low dose $\gamma$ radiation. Changes in the effective quantum yield of PSII, $\Phi_{PSII}$, and 1/Fo-1/Fm, a measure of the rate constant of excitation trapping by the PSII reaction center, showed similar pattern to Fv/Fm. And NPQ was decreased after photoinhibitory treatment showing no difference between the control and the 4 Gy irradiation group. These results showed the positive effect of low dose $\gamma$ radiation on the seedling growth and the reduction of photoinhibition.

예우 산악회

이혜연,Lee, Hye-Yeon 한국자연공원협회 1997 한국자연공원 Vol.66 No.-

조선 왕실과 대한제국 황실 어보 보수(寶綬)의 재료학적 분석

이혜연,김주영,조문경,김민지,박대우,이정민,Lee, Hyeyoun,Kim, Jooyoung,Cho, Mungyeong,Kim, Minji,Park, Daewoo,Lee, Jungmin 한국문화재보존과학회 2021 보존과학회지 Vol.37 No.2

조선의 어보는 국가 왕실을 상징하는 인장이다. 보수(寶綬)는 어보에 달린 붉은 끈으로, 어보의 품격을 높여주는 장식의 목적과 취급의 편리를 위해 제작되었다. 보수는 끈목과 방울술로 이루어졌다. 본 연구는 1441년부터 1928년까지 제작된 조선 왕실 및 대한제국 황실 어보의 보수 총 318점을 대상으로 형태 조사, 색상, 재질, 성분 분석 등을 실시하였다. 연구 결과 끈목은 시기가 후반으로 갈수록 길어지고 얇아지는 양상을 보인다. 방울술은 1800년대 중후반부터 방울목이 대부분 사라지고 술 끝에 고리가 나타난다. 보수의 색상은 대부분 다홍색이지만 주황색과 자주색도 확인된다. 보수의 재질은 대부분 실크로 확인되지만 1900년대 제작된 어보의 보수 5점과 1740년대에 제작된 어보의 보수 1점은 레이온으로 추정된다. 1740년대에 제작된 어보의 보수는 1900년대에 교체된 것으로 보인다. 방울술을 장식하는 금지의 주요 성분은 시대에 따라 달라진다. 1800년대 중반까지는 술과 방울에 금(Au)이 주요 성분인 금지를 사용하지만 1800년대 중반 이후부터 술에는 금(Au), 방울에는 황동(Cu-Zn)이 주요 성분인 금지를 사용하다가, 후반 이후 술과 방울에 황동이 주요 성분인 금지를 사용하였다. 보수는 어보의 한 부속품이지만 본 연구를 통하여 시대에 따른 제작 기법과 재질의 변화를 확인할 수 있었다. The royal seal, in either gold or jade, is used to symbolize Joseon's royal family, and it is made up of a Bonu (a handle), Bosin (a body), Bomun (a letter inscribed on the seal), and Bosu (a string attached to the seal). The Bosu was designed to enhance the seal's dignity and facilitate convenient handling. Bosu consists of Kkeun-mog and Bangwool-sul (decorated with gilt paper), which are made of Bangwool, Bangwool-mog, and Sul. In this study, the form survey, color, material, and composition of 318 Bosu pieces from the Joseon Dynasty and Korean Empire produced from 1441 to 1928 were analyzed. As time passed, the strings on the seals became longer and thinner. Bangwool-mog disappeared from the mid-1800s, and a ring appeared at the end of the Sul. Most of the colors used were scarlet, but orange and purple were also identified. Although most of the Bosu are silk, five Bosu from the 1900s and one Bosu from the 1740s (likely replaced in the 1900s) are estimated to be rayon. The gilt paper's main chemical components used to decorate the Bangwool-sul vary according to age. Until the mid-1800s, gold (Au) was used for the Sul and Bangwool, but since the mid-1800s, gold (Au) and brass (Cu-Zn) were used for Sul and Bangwool, respectively, and then brass (Cu-Zn) was used for Sul and Bangwool. While the Bosu was a seal accessory, it can be used to identify changes in the manufacturing techniques and materials of the period.

학교 급식 식단 중 잠재적으로 위험한 식품의 활용도 분석

이혜연,부고운,배현주,Lee, Hye-Yeon,Boo, Goun,Bae, Hyun-Joo 한국식품조리과학회 2015 한국식품조리과학회지 Vol.31 No.3

The objective of this study was to develop remedies to improve sanitary quality of school meals. To analyze the usage of potentially hazardous foods, menus from 180 school foodservice establishments were collected through school websites. Statistical analyses were conducted using the SPSS package program (ver. 20.0). The results of this study are as follows: analysis of the foodservice production process revealed that the following were employed: heating process (70.5%), non-heating process (16.3%), and after-heating process (13.2%). In addition, the cooking methods used for side dishes were: stir-frying (22.1%), saengchae (21.3%), sukchae (15.2%), jorim (12.4%), deep-frying (10.2%), and grilling (9.5%). Overall, 64 menu items known to pose potential microbiological hazards were offered a total of 2,671 times. The usage frequency was high for bibimbap, pork-bulgogi, cucumber-saenchae, seasoned bean sprouts namul, seasoned spinach-namul, and korean cabbage-geotjeori. In conclusion, in order to increase the sanitary quality of school meals, menus or foods that contain microbiological hazards should prepared very carefully with respect to time and temperature management during food production. Also, school foodservice employees must possess proper food safety knowledge and techniques for applying the HACCP system to prevent foodborne illness.

Survey on Hepatitis B virus and Hepatitis C Virus Coinfection in the Human Immunodeficiency Virus-infected Patients

이혜연,Hye-Yeoun Lee,김운호,Mi-Young Seo,Hak-Hyun Kim,Ji-Hye Park 대한미생물학회 2022 Journal of Bacteriology and Virology Vol.52 No.3

Human immunodeficiency virus (HIV), a blood-borne viral disease, weakens the immune system and causes opportunistic infections or cancers, which can eventually lead to Acquired Immune Deficiency Syndrome (AIDS). Generally antiretroviral therapy (ART) in HIV infected patients reduces morbidity and mortality, but also increases the risk of liver disease in patients coinfected with Hepatitis B virus (HBV) or Hepatitis C virus (HCV), previously known as the leading cause of death from HIV infection. In this study, HIV positive-sera were investigated seroprevalence of HBV and HCV which were requested for HIV test from 2020 to 2021. Of the total 232 samples, there are 184 cases (79.1%) in hospital, 33 cases (14.2%) in public health center, 6 cases (2.6%) in correctional institution and 2 cases (0.9%) in the military manpower administration. Hepatitis B virus surface antigen (HBsAg) was detected in 13 cases (5.6%) and hepatitis C virus antibody (anti-HCV) in 16 cases (6.9%) and also both in 4 cases (1.7%) of 232 samples. The results of HBsAg and hepatitis B virus core antibody (anti-HBc) for 107 samples were anti-HBc positive in 36 cases (35.6%) and HBsAg positive in 4 cases (1.7%). The results confirmed that coinfection with HBV and HCV was more common in HIV infected people than in the general population in Korea. These findings from this study were provided as fundamental data for HIV infection prevention and ART therapy selection.

감국 분말 첨가 쿠키의 관능적 특성 및 소비자 기호도

이혜연,배현주,Lee, Hye-Yeon,Bae, Hyun-Joo 한국식품영양학회 2010 韓國食品營養學會誌 Vol.23 No.1

This study was conducted to analyze sensory characteristics and consumer acceptance with cookies made using various levels(0, 2, 4, 6 and 8% w/w) of Chrysanthemum indicum L. powder. Ten panels assessed sensory characteristics using a 15-point hedonic scale and forty-five consumers evaluated their acceptance based on a 7-point hedonic scale and best-worst scaling. The descriptive analyses reveled that cookie flavor did not differ significantly between the 2% added sample and the control. Cookie color and after taste increased significantly, while hardness, roasted taste, and sweetness taste decreased significantly according to increasing Chrysanthemum indicum L. powder concentration. In addition, the results of consumer acceptance showed that the overall acceptability, appearance, color, flavor, and taste decreased significantly in response to increasing Chrysanthemum indicum L. powder concentration. However, color, flavor, taste and overall acceptance with cookies did not differ significantly differ between the 2% and 4% sample. Additionally, among the cookies made with Chrysanthemum indicum L. powder, the 2% sample received the highest scores. In conclusion, the sensory optimal ratio of Chrysanthemum indicum L. powder was 2% based on the descriptive analysis of sensory characteristics and the consumer-acceptance testing.

속리산 산행기

이혜연,Lee, Hye-Yeon 한국자연공원협회 1998 한국자연공원 Vol.69 No.-

PbTe/CuPc 이층박막의 광전 특성

이혜연,강영수,박종만,이종규,정중현 ( Hea Yeon Lee,Young Soo Kang,Jong Man Park,Jong Kyu Lee,Jung Hyun Jeong ) 한국센서학회 1998 센서학회지 Vol.7 No.1

The crystallized CuPc and PbTe films are formed by thermal evaporation and plused ArF excimer laser ablation. Structural and electrical properties of thin film is observed by XRD and current-voltage(I-V) curves. From XRD analysis, both PbTe and CuPc thin films show a-axis oriented structure. For the measurement of photovoltaic effect, the transverse current-voltage curve of CuPc/Si, PbTe/Si and PbTe/CuPc/Si junctions have been analyzed in the dark and under illumination. The PbTe/CuPc/Si junction exhibits a strong photovoltaic characteristics with short circuit current(J_(sc)) of 25.46 mA/㎠ and open-circuit voltage(V_(oc)) of 170 mV. Quantum efficiency and power conversion efficiency are calculated to be 15.4% and 3.46 x 10^(-2), respectively. Based on the results of QE and η, the photocurrent process of PbTe/CuPc/Si junction can be explained as following three effective steps; photocarrier generation in the CuPc layer, carrier separation at PbTe/CuPc interface, and finally a transportation of electrons through the PbTe layer.