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B형 인플루엔자와 관련되어 발생한 혈구포식 림프조직구증식증
이샘나 ( Saem Na Lee ),윤진구 ( Jin Gu Yoon ),조치현 ( Chi Hyun Cho ),최철원 ( Chul Won Choi ),최정윤 ( Jung Yoon Choi ),정희진 ( Hee Jin Cheong ),김우주 ( Woo Joo Kim ) 대한내과학회 2016 대한내과학회지 Vol.91 No.1
혈구포식 림프조직구증식증(HLH)은 대식세포와 림프구의 증식과 활성화가 조절되지 않아 발생하게 되는 드문 과염증 증후군으로, 치명적인 예후를 초래하는 경우가 많다. 저자들은 기저 질환이 없는 환자에서 B형 인플루엔자 감염과 연관되어 발생한 혈구포식 림프조직구증식증으로 인하여 사망한 증례를 경험하여 이를 보고하는 바이다. Influenza infection may be complicated by various infectious or non-infectious diseases. Among them, hemophagocytic lymphohistiocytosis (HLH) is an uncommon hyperinflammatory syndrome caused by uncontrolled proliferation and activation of macrophages and lymphocytes, and it is often life threatening. A previously healthy male patient was suspected to have HLH after influenza B infection. The diagnosis was established based on clinical diagnostic criteria suggested in the HLH-2004 trial. Despite prompt antiviral therapy, the patient expired on day 19 of hospitalization. Influenza can thus be complicated by HLH. Due to the non-specific manifestations of HLH, clinical suspicion and early diagnosis are important. (Korean J Med 2016;91:88-91)
Campylobacter jejuni Bacteremia in a Liver Cirrhosis Patient and Review of Literature: A Case Study
윤진구,이샘나,현학준,최민주,전지호,정은주,강성휘,김지용,노지윤,최원석,송준영,정희진,김우주 대한감염학회 2017 Infection and Chemotherapy Vol.49 No.3
Campylobacter infection causes gastrointestinal symptoms such as abdominal pain or diarrhea. Occasionally, Campylobacter bacteremia affects immunocompromised patients; however, serious outcomes are known to be rare. Here, we present a case of a patient with Campylobacter bacteremia who had underlying liver cirrhosis. The patient had fever and diarrhea. These symptoms subsided after treatment with cefotaxime. Campylobacter jejuni was isolated in the blood culture after 10 days. In addition, previously reported cases of Campylobacter bacteremia in Asian countries were reviewed with respect to antimicrobial sensitivities.
증례 : 감염: 신병훈련소의 군인에서 발생한 아데노바이러스 55형 폐렴
윤진구 ( Jin Gu Yoon ),이샘나 ( Saem Na Lee ),이정민 ( Jung Min Lee ),노지윤 ( Ji Yun Noh ),송준영 ( Joon Young Song ),정희진 ( Hee Jin Cheong ),김우주 ( Woo Joo Kim ) 대한내과학회 2016 대한내과학회지 Vol.90 No.4
Adenoviral pneumonia is rare in healthy adults. However, several cases were recently reported in a military training center in South Korea. Adenovirus genotype 3, 6, and 7 are predominant in South Korea. More recently, genotype 55, which emerged sporadically in China, has been reported in South Korea. In this study, we present a case of adenoviral pneumonia caused by genotype 55 in a healthy soldier from an army recruit training center in South Korea. (Korean J Med 2016;90:365-368)
Viral Shedding and Environmental Cleaning in Middle East Respiratory Syndrome Coronavirus Infection
송준영,정희진,최민주,전지호,강성희,정은주,윤진구,이샘나,김성란,노지윤,김우주 대한감염학회 2015 Infection and Chemotherapy Vol.47 No.4
Viral shedding lasted 31 and 19 days from symptom onset in two patients with east respiratory syndrome coronavirus (MERS-CoV) pneumonia, respectively. Environmental real-time RT-PCR was weakly positive for bed guardrail and monitors. Even after cleaning the monitors with 70% alcohol-based disinfectant, RT-PCR was still weakly positive, and converted to negative only after wiping with diluted sodium chlorite. Further studies are required to clarify the appropriate methods to clean environments during and after treatment of patients with MERS-CoV infection.
Perception and Attitudes of Korean Obstetricians about Maternal Influenza Vaccination
노지윤,서유빈,송준영,최원석,이재갑,정은주,강성휘,최민주,전지호,윤진구,이샘나,현학준,이진수,정호진,정희진,김우주 대한의학회 2016 Journal of Korean medical science Vol.31 No.7
Pregnant women are prioritized to receive influenza vaccination. However, the maternal influenza vaccination rate has been low in Korea. To identify potential barriers for the vaccination of pregnant women against influenza, a survey using a questionnaire on the perceptions and attitudes about maternal influenza vaccination was applied to Korean obstetricians between May and August of 2014. A total of 473 respondents participated in the survey. Most respondents (94.8%, 442/466) recognized that influenza vaccination was required for pregnant women. In addition, 92.8% (410/442) respondents knew that the incidence of adverse events following influenza vaccination is not different between pregnant and non-pregnant women. However, 26.5% (124/468) obstetricians strongly recommended influenza vaccination to pregnant women. The concern about adverse events following influenza vaccination was considered as a major barrier for the promotion of maternal influenza vaccination by healthcare providers. Providing professional information and education about maternal influenza vaccination will enhance the perception of obstetricians about influenza vaccination to pregnant women and will be helpful to improve maternal influenza vaccination coverage in Korea.