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B형 인플루엔자와 관련되어 발생한 혈구포식 림프조직구증식증
이샘나 ( Saem Na Lee ),윤진구 ( Jin Gu Yoon ),조치현 ( Chi Hyun Cho ),최철원 ( Chul Won Choi ),최정윤 ( Jung Yoon Choi ),정희진 ( Hee Jin Cheong ),김우주 ( Woo Joo Kim ) 대한내과학회 2016 대한내과학회지 Vol.91 No.1
혈구포식 림프조직구증식증(HLH)은 대식세포와 림프구의 증식과 활성화가 조절되지 않아 발생하게 되는 드문 과염증 증후군으로, 치명적인 예후를 초래하는 경우가 많다. 저자들은 기저 질환이 없는 환자에서 B형 인플루엔자 감염과 연관되어 발생한 혈구포식 림프조직구증식증으로 인하여 사망한 증례를 경험하여 이를 보고하는 바이다. Influenza infection may be complicated by various infectious or non-infectious diseases. Among them, hemophagocytic lymphohistiocytosis (HLH) is an uncommon hyperinflammatory syndrome caused by uncontrolled proliferation and activation of macrophages and lymphocytes, and it is often life threatening. A previously healthy male patient was suspected to have HLH after influenza B infection. The diagnosis was established based on clinical diagnostic criteria suggested in the HLH-2004 trial. Despite prompt antiviral therapy, the patient expired on day 19 of hospitalization. Influenza can thus be complicated by HLH. Due to the non-specific manifestations of HLH, clinical suspicion and early diagnosis are important. (Korean J Med 2016;91:88-91)
증례 : 감염: 신병훈련소의 군인에서 발생한 아데노바이러스 55형 폐렴
윤진구 ( Jin Gu Yoon ),이샘나 ( Saem Na Lee ),이정민 ( Jung Min Lee ),노지윤 ( Ji Yun Noh ),송준영 ( Joon Young Song ),정희진 ( Hee Jin Cheong ),김우주 ( Woo Joo Kim ) 대한내과학회 2016 대한내과학회지 Vol.90 No.4
Adenoviral pneumonia is rare in healthy adults. However, several cases were recently reported in a military training center in South Korea. Adenovirus genotype 3, 6, and 7 are predominant in South Korea. More recently, genotype 55, which emerged sporadically in China, has been reported in South Korea. In this study, we present a case of adenoviral pneumonia caused by genotype 55 in a healthy soldier from an army recruit training center in South Korea. (Korean J Med 2016;90:365-368)