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이상희,김성보,김진후,현창욱 국립문화재연구원 2023 헤리티지:역사와 과학 Vol.56 No.3
Korea is surrounded by the sea and has rivers connecting to it throughout the inland areas, which has been a geographical characteristic since ancient times. As a result, there have been exchanges and conflicts with various countries through the sea, and rivers have facilitated the transportation of ships carrying grain, goods paid for by taxes, and passengers. Since the past, the sea and rivers have had a significant impact on the lives of Koreans. Consequently, it is expected that there are many cultural heritages submerged in the sea and rivers, and continuous efforts are being made to discover and preserve them. Underwater cultural heritage is difficult to discover due to its location in the sea or rivers, making direct visual observation and exploration challenging. To overcome these limitations, various geophysical survey techniques are employed. Geophysical survey methods utilize the physical properties of elastic waves, including their reflection and refraction, to conduct surveys such as bathymetry, underwater topography and strata. These techniques detect the physical characteristics of underwater objects and seafloor formation in the underwater environment, analyze differences, and identify underwater cultural heritage located on or buried in the seabed. Bathymetry uses an echo sounder, and an underwater topography survey uses a side-scan sonar to find underwater artifacts lying on or partially exposed to the seabed, and a marine shallow strata survey uses a sub-bottom profiler to find underwater heritages buried in the seabed. However, the underwater cultural heritage discovered in domestic waters thus far has largely been accidental findings by fishermen, divers, or octopus hunters. This study aims to analyze and summarize the latest research trends in equipment used for underwater cultural heritage exploration, including bathymetric surveys, underwater topography surveys and strata surveys. The goal is to contribute to research on underwater cultural heritage investigation in the domestic context.
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발효 시금치 추출물의 무기인산염에 의해 유도된 혈관 석회화 저해 효과
이상희,홍선미,성미정 한국식생활문화학회 2022 한국식생활문화학회지 Vol.37 No.3
Spinach (Spinacia oleracea L.), a green leafy vegetable, is well known as a functional food due to its biological activities. Vascular calcification is associated with several disease conditions including atherosclerosis, diabetes, and chronic kidneydisease (CKD), and is known to raise the risk of cardiovascular diseases related morbidity and mortality. However, there areno previous studies that have investigated the effects of fermented spinach exract (FSE) against aortic and its underlyingmechanisms. Therefore, this study investigated the effects and action of possible mechanisms of FSE on inorganicphosphate (PI)-induced vascular calcification in ex vivo mouse aortic rings. PI increased vascular calcification throughcalcium deposition in ex vivo aortic rings. FSE inhibited calcium accumulation and osteogenic key marker, runt-relatedtranscription factor 2 (Runx2), and bone Morphogenetic Protein 2 (BMP-2) protein expression in ex vivo aortic rings. And,FSE inhibited PI-induced extracellular signal-regulated kinase (ERK) and p38 phosphorylation in ex vivo aortic rings. Theseresults show that FSE can prevent vascular calcification which may be a crucial way for the prevention and treatment ofvascular disease association with vascular calcification.
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