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한국형 후각검사 KVSS 검사에서 후각 인지 검사의 정답률에 관한 분석
안수연,공일규,이철희,김정훈 대한이비인후과학회 2007 대한이비인후과학회지 두경부외과학 Vol.50 No.12
Background and Objectives:KVSS (Korean Version of Snifin Sticks) identification test using 16 odorants familiar to Koreans is used for evaluation of olfactory function. We analyzed the correct-answer rate of the odor identification test among KVS test to validate the reliability of these odorants. Subjects and Method:From April 2004 through August 2006, 720 patients under-went an odor identification test and from these, 441 patients who scored more than 9 were included. The score groups were :more than 9, 10, 11 and 12 score group. The age groups were divided into 4 groups:0- 19, 20- 39, 40- 59, 60 and more than 60 year-olds. The diferences in the correct-answer rates of the odorant were investigated according to the score groups, age groups and sex were calculated using SPS software. Results:The odorant 6 (lemon), 7 (licorice), 8 (pine resin), and 11 (apple)rant 7 and 11 were significantly lower than other odorants except odorant 6 and 8 in all score groups, in all age groups and both sex (p≤.001). Conclusion:In the odor identification test, odorants 7 and 11 had low reliabililty for evaluation of the olfactory function, maybe due to unfamiliar odorants to Koreans or test pen failure and they had better be changed into more reliable odorants. For that, we need further investigations about KVSS test before widely used. (Korean J Otorhinolaryngol-Head ;50 :1109-13)
안수연,채금주,구진모 대한영상의학회 2018 Korean Journal of Radiology Vol.19 No.3
Objective: To compare the observer preference of image quality and radiation dose between non-grid, grid-like, and grid images. Materials and Methods: Each of the 38 patients underwent bedside chest radiography with and without a grid. A grid-like image was generated from a non-grid image using SimGrid software (Samsung Electronics Co. Ltd.) employing deep-learningbased scatter correction technology. Two readers recorded the preference for 10 anatomic landmarks and the overall appearance on a five-point scale for a pair of non-grid and grid-like images, and a pair of grid-like and grid images, respectively, which were randomly presented. The dose area product (DAP) was also recorded. Wilcoxon’s rank sum test was used to assess the significance of preference. Results: Both readers preferred grid-like images to non-grid images significantly (p < 0.001); with a significant difference in terms of the preference for grid images to grid-like images (p = 0.317, 0.034, respectively). In terms of anatomic landmarks, both readers preferred grid-like images to non-grid images (p < 0.05). No significant differences existed between grid-like and grid images except for the preference for grid images in proximal airways by two readers, and in retrocardiac lung and thoracic spine by one reader. The median DAP were 1.48 (range, 1.37−2.17) dGy*cm2 in grid images and 1.22 (range, 1.11−1.78) dGy*cm2 in grid-like images with a significant difference (p < 0.001). Conclusion: The SimGrid software significantly improved the image quality of non-grid images to a level comparable to that of grid images with a relatively lower level of radiation exposure.
Factors Related to Regional Recurrence in Early Stage Squamous Cell Carcinoma of the Oral Tongue
안수연,정은정,이명철,권택균,성명훈,전윤경,김광현 대한이비인후과학회 2008 Clinical and Experimental Otorhinolaryngology Vol.1 No.3
Objectives. This study analyzed various clinical and histopathologic factors for patients with early stage squamous cell carcinoma (SCC) of the oral tongue to define a high risk group for regional recurrence and finally to find out the indication of elective neck dissection (END). Methods. Retrospective chart review was performed for 63 patients with T1-T2N0 SCC of the oral tongue who underwent partial glossectomy with/without END. Clinical and histopathologic factors assessed were age, gender, clinical T stage, tumor cell differentiation, depth of invasion, pathologic nodal status, and intrinsic muscle involvement, perineural invasion, lymphovascular emboli and resection margin involvement. Results. Five year overall survival rate was 97.1% in stage I and 76.2% in stage II, and 5-yr disease free survival rate was 76.7% in stage I and 43.5% in stage II. Rates of occult nodal metastasis in stage I and II were 15.4% and 42.9%, respectively. Overall regional recurrence rate was 15.9%, which consisted of 10.2% in stage I and 35.7% in stage II. The success rate of salvage treatment was 100% in stage I and 40% in stage II. Higher T stage, higher histologic grade, depth of invasion ≥3 mm, presence of intrinsic muscle involvement were significantly related to regional recurrence (P=0.035, P=0.011, P=0.016, P=0.009, respectively). In stage I, the non-END group (n=36) showed 13.9% of regional recurrence rate, while END group (n=13) did not have any regional recurrence (P=0.198). Five year disease free survival rate of END group was significantly higher than non-END group (100% and 68.7%, respectively, P=0.045). Conclusion. We recommend to perform END in early stage SCC of the oral tongue if the primary tumor has T2 stage, and T1 stage with higher histologic grade, depth of invasion more than 3 mm, or presence of intrinsic muscle involvement. Objectives. This study analyzed various clinical and histopathologic factors for patients with early stage squamous cell carcinoma (SCC) of the oral tongue to define a high risk group for regional recurrence and finally to find out the indication of elective neck dissection (END). Methods. Retrospective chart review was performed for 63 patients with T1-T2N0 SCC of the oral tongue who underwent partial glossectomy with/without END. Clinical and histopathologic factors assessed were age, gender, clinical T stage, tumor cell differentiation, depth of invasion, pathologic nodal status, and intrinsic muscle involvement, perineural invasion, lymphovascular emboli and resection margin involvement. Results. Five year overall survival rate was 97.1% in stage I and 76.2% in stage II, and 5-yr disease free survival rate was 76.7% in stage I and 43.5% in stage II. Rates of occult nodal metastasis in stage I and II were 15.4% and 42.9%, respectively. Overall regional recurrence rate was 15.9%, which consisted of 10.2% in stage I and 35.7% in stage II. The success rate of salvage treatment was 100% in stage I and 40% in stage II. Higher T stage, higher histologic grade, depth of invasion ≥3 mm, presence of intrinsic muscle involvement were significantly related to regional recurrence (P=0.035, P=0.011, P=0.016, P=0.009, respectively). In stage I, the non-END group (n=36) showed 13.9% of regional recurrence rate, while END group (n=13) did not have any regional recurrence (P=0.198). Five year disease free survival rate of END group was significantly higher than non-END group (100% and 68.7%, respectively, P=0.045). Conclusion. We recommend to perform END in early stage SCC of the oral tongue if the primary tumor has T2 stage, and T1 stage with higher histologic grade, depth of invasion more than 3 mm, or presence of intrinsic muscle involvement.