단순헤르페스뇌염에서 무증상 혈종

송수진,나부석,송종민,우호걸,이도경,안태범,Song, Soo Jin,Na, Boo Suk,Song, Jong Min,Woo, Ho Geol,Lee, Dokyung,Ahn, Tae-Beom 대한임상신경생리학회 2015 Annals of Clinical Neurophysiology Vol.17 No.2

A 59-year old man was admitted for drowsiness and stiff neck. CSF examination showed lymphocytic pleocytosis and PCR for herpes simplex virus (HSV)-1 was positive in CSF. Brain MRI revealed enhanced lesions in left temporal lobe. His symptom improved with acyclovir. Follow-up studies showed red blood cells in CSF and a hematoma in the left temporal lobe. There was no additional symptom related to the hematoma. He was discharged after conservative care. Although rare, hematoma can develop in HSV-1 meningoencephalitis.

장애유아의 통합교육에 관한 비 장애유아 부모의 인식

송수진(Song, Soo Jin) 한국인권사회복지학회 2012 인권복지연구 Vol.- No.11

본 연구는 장애유아의 통합교육에 대한 일반유아 부모의 일반적 생각과, 장애통합교육에 대한 학습 및 교육면, 정서 및 사회성 발달에 대한 긍정적•부정적 영향에 대해 알아보고자 함을 목적으로 하였다. 연구방법은 통합교육에 관한 일반유아 부모의 인식에 대하여 알아보기 위하여 장애통합 교육을 시행하고 있는 인천시 남동구 법인어린이집의 일반 유아 부모를 대상으로 설문지를 배포하였으며, 수거된 123개의 설문지를 분석하였다. 이상과 같은 연구과정을 통해 다음과 같은 결과를 얻었다. 첫째, 통합교육에 대한 일반적 생각에서는 중간 점수 이상의 긍정적인 인식을 가지고 있는 것으로 나타났다. 둘째, 장애유아 통합교육으로 인한 학습 및 교육면에 있어서 학습 진도가 늦어질 수 있으나, 배려하는 마음을 갖고, 협력하면 나아질 거라는 긍정의 생각을 갖고 있으며, 교사들로부터 교육적인관심을 덜 받지 않을 것이라는 긍정보다는 보통의 결과가 나타났다. 또 학습 진도에 방해가 되거나 일반유아가 소홀히 다루어지지 않을 것이라는 인식도 보통의 긍정보다는 보통의 결과가 나타났다. 그러나 장애유아와 일반유아가 함께 단계별로 배우는 과정에서 인간의 존엄성을 느끼고, 배우는 기회가 더 많을 것으로 나타났다. 셋째, 통합교육을 통한 정서 및 사회성 발달 면에 있어서 장애유아들은 일반유아의 행동을 모방하고 상호작용을 통해서 사회적인 가능을 빠르게 학습하게 되며, 일반유아들은 타인을 배려하는 마음과 사람들의 다양성을 잘 수용할 것이라고 인식하고 있는 것으로 나타났다. 따라서 결론적으로 일반유아 부모들은 장애통합에 대해 긍정적인 인식을 갖고 있다는 것을 알 수 있는데 그 이유는 통합교육을 통해 장애유아가 또래와의 관계 속에서 사회적응 능력의 발달과 대인 관계 형성 기술 발달에 도움을 받기 때문에 긍정적인 인식을 갖고 있는 것으로 조사되었다. The purpose of this study is to find out the parents's role in the integration education of disabled infants, the general perspectives of non-disabled infants's parents, the need of the integration education with disabled infants, and the influential factors of the integration education with disabled infants. This study is largely divided into 5 chapters, Chapter 1 describes the purpose, scope and the method of the study and Chapter 2 looks into the need of the integration education with disabled infants, educational effects of the integration education and the parents' role. In Chapter 3, the evidence analysis on the parents' role, In Chapter 4, perspectives on integration education was made limited on the sample. Based on Chapter 5 concludes as non-disabled infants attitude and perspectives are influenced by the adults around them and their parents' perspectives and attitued on the disability and the integration education will make direct influence on their children, they should play supportive role accordingly. This study suggests it requires non-disabled infants parents' active efforts so the intants as the future society members may have correct perspectives on the disability and play basic roles to make the togetherness society. Multiple aspects of parents education program support is expected to make the opportunity to prepare the changes in perspectives of non disable infants parents, in order to achieve suuccessful integration education with disabled infants.

소나무림의 간벌이 생체량과 토양의 호흡 및 메탄발생에 미치는 영향

송수진 ( Su Jin Song ),장경수 ( Kyoung Soo Jang ),황인채 ( In Chae Hwang ),윤동준 ( Dong Jun Yun ),최종회 ( Jong Hoe Choi ),이계한 ( Kye Han Lee ) 한국임학회 2014 산림과학 공동학술대회 논문집 Vol.2014 No.-

본 연구는 간벌에 따른 수목의 생체량과 토양 이산화탄소와 메탄발생량을 추정하고 연간 탄소 동태 파악을 목적으로 수행되었다. 식재 후 5년 된 소나무 묘포장에 대조구, 간벌지(50%), 개벌지, 나지를 3 반복으로 조성하여 2012년 3월부터 2014년 2월까지 수목 생장량은 매 년 1회, 토양 호홉량은 매 월 1회 측정하였으며, 메탄발생량은 2012년 5월부터 2013년 4월까지 매 월 1회 측정하였다. 수목 생체량은 실험 7개월 전 간벌을 통한 벌채와 실험이 마무리 된 직후 벌채를 통해 유도된 바이오매스 상대생장식을 이용하였다. 직경생장은 대조구와 간벌지간의 유의한 차이가 있었으나 (p<0.05)수고생장은 유의한 차이가 나타나지 않았다. 조사기간 동안 대조구, 간벌지, 개벌지, 나지에서의 연간토양 호흡량은 3.71, 3.90, 4.17, 4.56 kg C m-2·yr-1으로 나지에서 가장 높았고 메탄발생량은 각각 4.98-34.6, 1.62-31.99, 3.11-28.82, 1.28-19.33 μg C m-2 h-1이며, 연간 메탄발생량은 각각 0.15, 0.10, 0.09, 0.06 g C m-2 yr-1이었다. 토양 호흡량은 토양 온도와 토양 메탄발생은 토양수분과 각각 유의적인 상관관계가 있었다 (p<0.05). 연구 결과 간벌은 임목의 생체량을 증가시키고 토양 메탄발생량을 감소시켰으나, 토양 호흡량에는 큰 영향을 미치지 않았다. Objectives of the study were to examine carbon dynamics via NPP, soil CO2 and CH4 efflux following thinning and understand short-term carbon-partitioning patterns after thinning in a young Pinus densiflora stand. We established stand with 50% of thinning, clear-cut, trenched without roots, and control stands with three pseudo-replicated plots. Soil CO2 efflux was measured using infrared gas analyser(IRGA) from March 2012 to February 2014, CH4 emission was measured from May 2012 to April 2013, and NPP of aboveground and coarse-roots were estimated by derived allometric equations. Mean diameter increment in the thinning was significantly higher in control stand (p<0.05). However, annual height increment was not significantly different between the stands. Annual total soil respiration in control, thinned, clear cut, and trenched was 3.71, 3.39, 4.17, 4.56 kg C m-2 yr-1, respectively. Soil methane emissions ranged 4.98-34.60, 1.62-31.99, 3.11-28.82, and 1.28-19.33 μmol m-2 s-1 in control, thinned, clear-cut, and trenched, respectively. Annual total soil methane emissions in control, thinned, clear-cut, and trenched was 0.15, 0.10, 0.09, 0.06 kg C m-2 yr-1, respectively. Soil CO2 efflux was significantly related to soil temperature (p<0.05) and soil CH4 emission was significantly related to soil moisture (p<0.05). The results indicate that carbon dynamics via NPP has increased and CH4 efflux has decreased by thinning. However, soil CO2 was little affected by thinning.

소나무 유령림의 임목밀도 조절이 탄소 동태에 미치는 영향

송수진 ( Su-jin Song ),장경수 ( Kyoung-soo Jang ),황인채 ( In-chae Hwang ),안기완 ( Ki-wan An ),이계한 ( Kye-han Lee ) 한국임학회 2016 한국산림과학회지 Vol.105 No.3

본 연구는 소나무림의 간벌에 따른 임분의 바이오매스 변화, 토양 CO₂ 발생량, 낙엽 및 뿌리의 분해율을 조사하여 연간 탄소 동태를 파악하고자 수행되었다. 8년생 소나무 묘포장에 대조구, 간벌지(50%), 개벌지를 각 3 방형구씩 조성하였고, 나지는 한 방형구를 조성하였다. 측정은 2012년 3월부터 2014년 2월까지 이뤄졌다. 연평균 근원직경 증가는 대조구 0.89 cm, 간벌지 1.48 cm로 대조구보다 간벌지에서 컸다(p<0.05). 연평균 순생산량은 대조구 5.17 kg C m^­2 yr^­1, 간벌지 4.85 kg C m^-2 yr^-1로 나타났다. 연간 토양 CO₂ 발생량은 대조구, 간벌지, 개벌지, 나지에서 각각 3.71, 3.90, 4.17, 4.56 kg CO₂ m^-2 yr^-1으로 식생의 제거는 토양 CO₂ 발생을 증가시켰다(P<0.05). 토양 CO₂발생은 토양온도와 양의 상관관계가 있으나 토양수분과는 뚜렷한 관계가 나타나지 않았다. 순생태계생산량(NEP)은 대조구 1.57 kg C m^-2 yr^-1, 간벌지 1.36 kg C m^-2 yr^-1, 개벌지 -0.67 kg C m^-2 yr^-1, 나지 -1.25 kg C m^-2 yr^-1으로, 식생 유무에 따른 차이를 나타냈다(P<0.05). 간벌은 임분 내 개체목의 근원직경과 탄소량을 증가시켰고, 1년 후 간벌재로 반출 된 탄소량의 86%를 회복했다. 또한 토양 CO₂ 발생량을 증가시켰고, 순생태계생산량을 증가시켰다. 소규모의 연구임에도 불구하고, 본 연구의 결과는 간벌에 의한 임분 밀도 조절이 소나무 유령림의 탄소저장량 증대와 생장에 있어 효과적임을 보여 주었다. 이는 우리나라에서 기후변화 완화를 위한 적극적인 소나무림의 경영이 필요함을 시사한다. 추후 실제 소나무림에서 영급별, 간벌 강도별, 지위별 등 다양한 변수를 고려한 장기적 연구가 수행되어야 할 것이다. The objective of this study was to examine carbon dynamics with biomass, soil CO₂ efflux, litter and root decomposition after tree density control in young Pinus densiflora stands. The stands were established with 50% thinning, clear-cut, and control stands with three pseudo-replicated plots and a bare soil plot in 8-year-old Pinus densiflora nursery field. Monthly measurements were conducted from March 2012 to February 2014 and aboveground biomass and coarse-roots were estimated by derived allometric equations. Average diameter growth at root collar in control and thinned was 0.89 cm and 1.48 cm per year, respectively, and the diameter growth of control stand was significantly higher than that of thinned stands (p<0.05). Total biomass was estimated to 5.17, 4.85 kg C m^-2 per year in control and thinned, respectively. Annual soil CO₂ efflux in control, thinned, clear cut, and bare soil was 3.71, 3.90, 4.17, 4.56 kg CO₂ m^-2 yr^-1, respectively and removing trees significantly increased soil CO₂ efflux (p<0.05). Net Ecosystem Production (NEP) was 1.57, 1.36, -0.67, -1.25 kg C m^-2 yr^-1 in control, thinned, clear cut and bare soil in the young Pinus densiflora stands. NEP was significantly decreased by removing trees. Thinning increased diameter at root collar and carbon of individual tree and recovered 86% of carbon removed by thinning after one-year. In addition, soil CO₂ efflux increased and NEP increased by thinning. Results of this study, tree density control such as thinning increased the carbon storage and growth of the young Pinus densiflora stands.

SH-SY5Y 세포에서 도네페질과 병용투여시 신경보호 효과를 나타내는 한약재의 in vitro 선별 연구

송수진 ( Sue-jin Song ),류천봉 ( Quan Feng Liu ),홍민호 ( Min-ho Hong ),김근우 ( Geun-woo Kim ),구병수 ( Byung-soo Koo ) 대한한방신경정신과학회 2019 동의신경정신과학회지 Vol.30 No.3

Objectives: The purpose of this study was to evaluate the neuroprotective effects of donepezil and 33 kinds of herbal extract combinations in SH-SY5Y cells with Aβ _25-35 treatment. Methods: MTT assay was performed to measure the cell viability of each herbal extract combined with donepezil against Aβ-induced neurotoxicity. The most active extracts were then subjected to assess the effects on CREB phosphorylation and COX-2 expressions through the western blot analysis. Results: There were eight herbal extracts representing significant increase on the cell viability: 1) Erycibe obtusifolia, 2) Polygonum multiflorum, 3) Polygala tenuifolia, 4) Illicium verum, 5) Santalum album, 6) Loranthus parasticus, 7) Platycladus orientalis, and 8) Zanthoxylum piperitum. Especially, when Santalum album and donepezil were treated together, the phosphorylation of CREB significantly increased and COX-2 protein expression was significantly inhibited. Conclusions: Among the screened herbal extracts, combination treatment of each of the eight herbs and donepezil showed neuroprotective effects in SH-SY5Y cells. Additionally, the combination of Santalum album and donepezil suggested cognitive improvement by up-regulation of p-CREB and down-regulation of COX-2.

급성뇌졸중 양상으로 발현된 췌장암의 연수막 전이

나부석,송수진,송종민,우호걸,권영남,이도경,안태범,Boo Suk Na,Soo Jin Song,Jong Min Song,Ho Geol Woo,Young Nam Kwon,Dokyung Lee,Tae-Beom Ahn 대한소화기암연구학회 2015 Journal of digestive cancer reports Vol.3 No.2

Pancreatic cancer is commonly presented with distant metastasis. However metastasis to central nervous system (CNS) of pancreatic cancer was rarely reported. 79-years-old man was hospitalized with sudden onset right arm dysesthesia and weakness. In brain magnetic resonance imaging, multifocal high signal intensity lesions in cerebral and cerebellar cortices were observed. Leptomeningeal and parenchymal enhanced lesions were also noted in contrast-enhanced T1 images suggesting a metastasis from the pancreatic cancer. Stroke like manifestation of CNS metastasis of pancreatic cancer is extremely rare. Careful history taking and evaluation should be performed to find the origin of the sudden neurologic deficit.

혈중 E2 농도가 체외수정술의 임신율에 미치는 영향

박세희 ( Sea Hee Park ),주보선 ( Bo Sun Joo ),송수진 ( Soo Jin Song ),김경서 ( Kyung Sue Kim ),문성은 ( Sung Eun Moon ),문화숙 ( Hwa Sook Moon ) 대한산부인과학회 2008 Obstetrics & Gynecology Science Vol.51 No.11

목적: hCG 투여 당일 혈중 E2 농도가 체외수정술의 임신결과에 미치는 효과를 조사하고자 한다. 방법: 체외수정시술을 시행받은 455 주기를 대상으로 hCG 주사 당일 측정한 E2 농도에 따라 A군 (<1,000 pg/mL), B군 (1,000~2,000 pg/mL), C군 (2,000~3,000 pg/mL), D군 (3,000~4,000 pg/mL), E군 (≥4,000 pg/mL)으로 나눈 다음 체외수정술 결과를 비교하였다. 결과: hCG 투여 당시 혈중 E2 농도는 평균 3,745.3 pg/mL였으며, 채취된 평균 난자수는 10.1개였다. 148주기 (32.5%)에서 임상적 임신이 확인되었으며, 착상률 12.2%, 분만율 18.7%였다. E2 농도가 증가할수록 채취된 난자수는 증가된 경향을 나타냈다. 임신율 또한 E2 농도가 증가함에 따라 점차 증가하다가 D군 (50.0%)에서 가장 높은 다음, E군에서 다시 감소하였다. 38세 미만 여성에서는 전체 환자 군에서와 유사한 결과를 보인 반면, 38세 이상 여성에서는 임신율과 분만율 모두 C군에서 유의하게 가장 높았다. 결론: 이러한 결과는 혈중 E2 농도가 농도 의존적으로 임신결과에 영향을 미칠 수 있으며, 임신결과와 양성적 상관관계를 가지는 최적의 E2 농도 범위가 있음을 시사하고 있다. 과도한 E2 농도에 의한 임신결과의 저해는 여성 나이가 38세 이상일 경우 더욱 민감하였다. Objective: To evaluate the effects of serum E2 levels on the day of hCG administration on the pregnancy outcome of IVF-ET after controlled ovarian hyperstimulation (COH). Methods: Data of 455 cycles of fresh IVF-ET with COH were retrospectively investigated. Serum E2 levels on the day of hCG administration were categorized into 5 groups; A (<1,000 pg/mL), group B (1,000~2,000 pg/mL), group C (2,000~3,000 pg/mL), group D (3,000~4,000 pg/mL), and group E (≥ 4,000 pg/mL). Results: Mean E2 levels on the day of hCG administration were 3,745.3 pg/mL and mean number of retrieved oocytes were 10.1. Of 455 cycles, 148 (32.5%) cycles were clinically pregnant. Implantation rate was 12.2% and delivery rate was 18.7%. The number of obtained oocytes increased with increasing levels of serum E2. Pregnancy rate gradually increased as E2 levels increased up to the group D, but began to fall in the group E. In younger women (<38 yrs), the IVF-ET outcomes were similar to those of total patients but in older women (≥38 yrs), pregnancy rate and delivery rate were significantly higher in the group C than other groups. Conclusions: This result shows that serum E2 levels have a concentration-dependent effect on the pregnancy outcome and there is an optimal range of E2 levels to achieve for a successful pregnancy. Excessive E2 levels seem more deleterious to the pregnancy outcome in older women aged ≥38 years.

식이 섬유소 및 실크 펩타이드 보충이 영양소 섭취상태, 체적지수 및 복부 비만에 미치는 영향에 관한 연구

이성희,최애진,송수진,류정민,노숙령,황영희 대한영양사협회 2002 대한영양사협회 학술지 Vol.8 No.2

This study is to investigate consequent nutrient intake status, influence of body mass index(BMI), and fat distribution on the silk amino peptide(SAP) and dietary fiber supplementation. During 2 months of this research(January to March, 2002), 45 women aged 20yr - 30yr(average age 24.6yr) were selected as subjects. Nutrient intake was investigated by questionnaire, 24-hr recall method. Antropometric assessments of the subjects were investigated by SBIA method(Segmental bioimpedance assay, In body 3.0). The results are as follows: mean body weight 57.7kg, mean body height 161.9cm mean BMI 22.0, and mean food habit score was 8.47. Defecation frequency was increased by dietary fiber supplementation. Frequency of pain during defecation was significantly decreased by dietary fiber supplementation(p<0.01). Feeling of residual feces was significantly improved by dietary fiber supplementation(p<0.001). Status of energy and carbohydrate intakes significantly decreased after dietary fiber supplementation(p<0.05). Body fat and WHR(waist hip ratio) significantly decreased after dietary fiber supplementation(p<0.001), and percent body fat was decreased by dietary fiber supplementation, significantly(p<0.05). Above results of this study show that dietary fiber-added routine diet improves defecation condition, and lessens body fat, percent body fat without losing body muscle. Especially, declination of abdominal fat and WHR were notable. That meant decreased risk factor.