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( Dong Hoon Yang ),( Suk Kyun Yang ),( Sang Hyoung Park ),( Ho Su Lee ),( Sun Jin Boo ),( Jae Ho Park ),( Soo Young Na ),( Kee Wook Jung ),( Kyung Jo Kim ),( Byong Duk Ye ),( Jeong Sik Byeon ),( Seung 대한소화기학회 2015 Gut and Liver Vol.9 No.1
Background/Aims: C reactive protein (CRP) is a serologic activity marker in Crohn`s disease (CD), but it may be less useful in evaluating CD activity in ileal CD patients. We aimed to investigate the usefulness of CRP as a disease activity marker in CD according to disease location. Methods: Korean CD patients in a single hospital were evaluated. Factors associated with elevated CRP concentration at the time of diagnosis of CD and the association between the physician`s prediction regarding upcoming surgery and the sites of the lesions directly related to surgery were analyzed. Results: Of 435 CD patients, 25.7%, 6.9%, and 67.4% had ileal, colonic, and ileocolonic CD, respectively. Multivariate analysis revealed that an elevated erythrocyte sedimentation rate, reduced serum albumin, CD activity index (CDAI) >220, and ileocolonic/colonic location were associated with an elevated CRP level and that the CRP level was significantly correlated with the CDAI in all CD patients (γ=0.466, p<0.01). However, the correlation coefficient was dependent on the location, with values of 0.395, 0.456, and 0.527 in patients with an ileal, ileocolonic, and colonic disease location, respectively. Surgery for ileal lesions was less predictable than surgery for ileocolonic or colonic lesions during follow up. Conclusions: CRP is less useful as a disease activity marker in patients with ileal CD than those with ileocolonic or colonic CD. (Gut Liver 2015;9:80 86)
( Jung Hwan Lee ),( Yoo Kyung Cho ),( Mu Suk Lee ),( Seung Hyoung Kim ),( Seung Uk Jeong ),( Soo Young Na ),( Sun Jin Boo ),( Hyun Joo Song ),( Eun Kwang Choi ),( Heung Up Kim ),( Byung Cheol Song ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Background: Most hepatic cysts are asymptomatic liver disease. Rarely, hepatic cysts will be symptomatic because of increasing size, infection and hemorrhage. We describe clinical characteristics of symptomatic hepatic cysts and its effective treatment. Methods: We performed a retrospective review of all patients diagnosed with symptomatic hepatic cysts between May 2009 and April 2013 in Jeju National University Hospital. Twenty one symptomatic hepatic cysts (mean diameter 10.7 cm, ranged 4.5- 16 cm) in 14 patients (12 women and 2 men, aged 51-81 years) were enrolled. Results: Symptoms of hepatic cysts were right upper abdominal pain (10 patients), recurrent lower extremities edema (2 patients), fever (3 patients), right shoulder radiating pain (1 pstient). All symptomatic hepatic cysts were treated with percutaneous drainage (mean volume 480 ml ± 325 ml). Three infected cysts were diagnosed by cystic fl uid analyses and treated using antibiotics. After cystogram, 20 hepatic cysts were performed 99.9% ethanol sclerotherapy three times in a row. There were few minor complications including pain, nausea, vomiting. During follow-up (11 months), there was no recurrence. The mean diameter of remained cysts decreased to 3.2 cm with an average volume reduction rate of 92.3 % (from 464.1 cm3 to 35.8 cm3). Conclusions: Percutaneous drainage and ethanol sclerotherapy is a very effective and safety treatment method of symptomatic hepatic cysts.
Park, Yoon-Sung,Hong, Sung-Jin,Boo, Yoo-Kyung,Hwang, Eun-Suk,Kim, Hyun Jung,Cho, Seung-Hee,Na, Kyung-In,Cho, En-Hi,Shin, Sang-Sook The Korean Academy of Tuberculosis and Respiratory 2012 Tuberculosis and Respiratory Diseases Vol.73 No.1
Background: The epidemiology of tuberculosis (TB) has been assessed based on the data of the analysis of TB patients notified to the surveillance system in Korea. However, the national status of TB is not validated through this surveillance system. The objective is to determine the epidemiology of TB and to understand the accurate status of TB patients treated in private institutions. Methods: Medical records of 53,579 patients who had been diagnosed with TB in 2008 were analyzed. Results: Among 53,579 patients, the number of sputum smear positive cases was 15,639(29.2%) and the number of new cases was 39,191 (73.1%). The drug resistance rate of new cases was 5.3%, while the rate stood at 13.3% for TB patients with treatment history. The number of multi-drug resistant TB (MDR-TB) patients was 2,472 (4.6%), which consists of 2.9% of new cases and 9.3% of TB patients with prior treatment history. The number of extensively drug-resistant TB patients was 749 (1.4%), consisting of 1.1% of new cases and 2.2% of TB patients with prior treatment history. In terms of treatment outcomes, 66.4% of all TB patients, 70.5% of new cases, 64.4% of relapse cases, and 46.8% of MDR-TB cases were cured or completed. It was inferred that in 2008, the total number of TB patients reached 70,767, 145.6 per 100,000 people (95% confidence interval, 145.5~145.7). Conclusion: We conclude that the medical records review of the Health Insurance Review and Assessment Service (HIRA) data can be very effective in promoting the understanding of the current status of TB in private institutions.
나부석,송수진,송종민,우호걸,권영남,이도경,안태범,Boo Suk Na,Soo Jin Song,Jong Min Song,Ho Geol Woo,Young Nam Kwon,Dokyung Lee,Tae-Beom Ahn 대한소화기암연구학회 2015 Journal of digestive cancer reports Vol.3 No.2
Pancreatic cancer is commonly presented with distant metastasis. However metastasis to central nervous system (CNS) of pancreatic cancer was rarely reported. 79-years-old man was hospitalized with sudden onset right arm dysesthesia and weakness. In brain magnetic resonance imaging, multifocal high signal intensity lesions in cerebral and cerebellar cortices were observed. Leptomeningeal and parenchymal enhanced lesions were also noted in contrast-enhanced T1 images suggesting a metastasis from the pancreatic cancer. Stroke like manifestation of CNS metastasis of pancreatic cancer is extremely rare. Careful history taking and evaluation should be performed to find the origin of the sudden neurologic deficit.
( Yoon Sung Park ),( Sung Jin Hong ),( Yoo Kyung Boo ),( Eun Suk Hwang ),( Hyun Jung Kim ),( Seung Hee Cho ),( Kyung In Na ),( En Hi Cho ),( Sang Sook Shin ) 대한결핵 및 호흡기학회 2012 Tuberculosis and Respiratory Diseases Vol.73 No.1
Background: The epidemiology of tuberculosis (TB) has been assessed based on the data of the analysis of TB patients notified to the surveillance system in Korea. However, the national status of TB is not validated through this surveillance system. The objective is to determine the epidemiology of TB and to understand the accurate status of TB patients treated in private institutions. Methods: Medical records of 53,579 patients who had been diagnosed with TB in 2008 were analyzed. Results: Among 53,579 patients, the number of sputum smear positive cases was 15,639(29.2%) and the number of new cases was 39,191 (73.1%). The drug resistance rate of new cases was 5.3%, while the rate stood at 13.3% for TB patients with treatment history. The number of multi-drug resistant TB (MDR-TB) patients was 2,472 (4.6%), which consists of 2.9% of new cases and 9.3% of TB patients with prior treatment history. The number of extensively drug-resistant TB patients was 749 (1.4%), consisting of 1.1% of new cases and 2.2% of TB patients with prior treatment history. In terms of treatment outcomes, 66.4% of all TB patients, 70.5% of new cases, 64.4% of relapse cases, and 46.8% of MDR-TB cases were cured or completed. It was inferred that in 2008, the total number of TB patients reached 70,767, 145.6 per 100,000 people (95% confidence interval, 145.5∼145.7). Conclusion: We conclude that the medical records review of the Health Insurance Review and Assessment Service (HIRA) data can be very effective in promoting the understanding of the current status of TB in private institutions.
송수진,나부석,송종민,우호걸,이도경,안태범,Song, Soo Jin,Na, Boo Suk,Song, Jong Min,Woo, Ho Geol,Lee, Dokyung,Ahn, Tae-Beom 대한임상신경생리학회 2015 Annals of Clinical Neurophysiology Vol.17 No.2
A 59-year old man was admitted for drowsiness and stiff neck. CSF examination showed lymphocytic pleocytosis and PCR for herpes simplex virus (HSV)-1 was positive in CSF. Brain MRI revealed enhanced lesions in left temporal lobe. His symptom improved with acyclovir. Follow-up studies showed red blood cells in CSF and a hematoma in the left temporal lobe. There was no additional symptom related to the hematoma. He was discharged after conservative care. Although rare, hematoma can develop in HSV-1 meningoencephalitis.