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아동학대 예방 및 피해 아동의 효율적 지원을 위한 개선방안
송수진(Song Sue Jin) 한국가족법학회 2016 가족법연구 Vol.30 No.3
As a social issue which has existed world-wide for a long time, child abuse is a problem that we must solve together. In order to prepare an improvement plan to prevent child abuse and to quickly and efficiently protect and support abused children, this study will examine current problems within the existing child abuse punishment law, including the child welfare law, Civil law, related contents from the special law on domestic violence, and current problematic points of the support system process for child abuse. First of all, in the preventive stages of child abuse, there is a need to create a social atmosphere that respects children, guarantees children’s rights, and which changes the attitude of parents towards their children and their awareness on parental rights. For this purpose, the parts of the Civil law that states ‘parent and children’ or ‘parental rights’ must be changed to ‘obligation or responsibility of parents.’ Occupational group of ‘Person who is obliged to report’ should be expanded, and there is a need to reinforce education. And most importantly, to fundamentally prevent child abuse, corporal punishment on children should be completely banned, and legislation that disallows the exemption of corporal punishment as a justifiable act under article 915 of the Civil law which regulates the disciplinary authority of parents, should be legalized. Secondly, in the stages of protection and support for abused children, the types and ranges of child abuse should be extended, and in the event that emergency measures need to be taken on the site of child abuse, the regulation that respects the abused child’s thoughts should be deleted so that the abused child can be realistically protected. Also, for the safe supporting of abused children, when moving out to site, the accompaniment by an employee of the Child protection institute (counsellor), and a police officer should be made obligatory, and penalty or punishment rules should be determined for the abuser who refuses an onsite investigation. As well, legislation should aid the situation by means of such as appointing a lawyer that represents the child in all processes of handling the child abuse case. The law needs to be revised in order to activate a guardian system that appropriately utilizes measures that limits parental rights, reinforces local infrastructure to protect abused children, and develops a comprehensive approach on child abuse. Lastly, in order to prevent child abuse and have an efficient support system, eventually a thorough inspection and management should be done through a control tower which looks over not only child abuse but also domestic violence, and abuse of the elderly, which are all organically related. As well, changing the citizens’ awareness of child abuse through continuous publicity activities and preventive education is the most important.
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SH-SY5Y 세포에서 도네페질과 병용투여시 신경보호 효과를 나타내는 한약재의 in vitro 선별 연구
송수진 ( Sue-jin Song ),류천봉 ( Quan Feng Liu ),홍민호 ( Min-ho Hong ),김근우 ( Geun-woo Kim ),구병수 ( Byung-soo Koo ) 대한한방신경정신과학회 2019 동의신경정신과학회지 Vol.30 No.3
Objectives: The purpose of this study was to evaluate the neuroprotective effects of donepezil and 33 kinds of herbal extract combinations in SH-SY5Y cells with Aβ <sub>25-35</sub> treatment. Methods: MTT assay was performed to measure the cell viability of each herbal extract combined with donepezil against Aβ-induced neurotoxicity. The most active extracts were then subjected to assess the effects on CREB phosphorylation and COX-2 expressions through the western blot analysis. Results: There were eight herbal extracts representing significant increase on the cell viability: 1) Erycibe obtusifolia, 2) Polygonum multiflorum, 3) Polygala tenuifolia, 4) Illicium verum, 5) Santalum album, 6) Loranthus parasticus, 7) Platycladus orientalis, and 8) Zanthoxylum piperitum. Especially, when Santalum album and donepezil were treated together, the phosphorylation of CREB significantly increased and COX-2 protein expression was significantly inhibited. Conclusions: Among the screened herbal extracts, combination treatment of each of the eight herbs and donepezil showed neuroprotective effects in SH-SY5Y cells. Additionally, the combination of Santalum album and donepezil suggested cognitive improvement by up-regulation of p-CREB and down-regulation of COX-2.
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박세희 ( Sea Hee Park ),주보선 ( Bo Sun Joo ),송수진 ( Soo Jin Song ),김경서 ( Kyung Sue Kim ),문성은 ( Sung Eun Moon ),문화숙 ( Hwa Sook Moon ) 대한산부인과학회 2008 Obstetrics & Gynecology Science Vol.51 No.11
목적: hCG 투여 당일 혈중 E2 농도가 체외수정술의 임신결과에 미치는 효과를 조사하고자 한다. 방법: 체외수정시술을 시행받은 455 주기를 대상으로 hCG 주사 당일 측정한 E2 농도에 따라 A군 (<1,000 pg/mL), B군 (1,000~2,000 pg/mL), C군 (2,000~3,000 pg/mL), D군 (3,000~4,000 pg/mL), E군 (≥4,000 pg/mL)으로 나눈 다음 체외수정술 결과를 비교하였다. 결과: hCG 투여 당시 혈중 E2 농도는 평균 3,745.3 pg/mL였으며, 채취된 평균 난자수는 10.1개였다. 148주기 (32.5%)에서 임상적 임신이 확인되었으며, 착상률 12.2%, 분만율 18.7%였다. E2 농도가 증가할수록 채취된 난자수는 증가된 경향을 나타냈다. 임신율 또한 E2 농도가 증가함에 따라 점차 증가하다가 D군 (50.0%)에서 가장 높은 다음, E군에서 다시 감소하였다. 38세 미만 여성에서는 전체 환자 군에서와 유사한 결과를 보인 반면, 38세 이상 여성에서는 임신율과 분만율 모두 C군에서 유의하게 가장 높았다. 결론: 이러한 결과는 혈중 E2 농도가 농도 의존적으로 임신결과에 영향을 미칠 수 있으며, 임신결과와 양성적 상관관계를 가지는 최적의 E2 농도 범위가 있음을 시사하고 있다. 과도한 E2 농도에 의한 임신결과의 저해는 여성 나이가 38세 이상일 경우 더욱 민감하였다. Objective: To evaluate the effects of serum E2 levels on the day of hCG administration on the pregnancy outcome of IVF-ET after controlled ovarian hyperstimulation (COH). Methods: Data of 455 cycles of fresh IVF-ET with COH were retrospectively investigated. Serum E2 levels on the day of hCG administration were categorized into 5 groups; A (<1,000 pg/mL), group B (1,000~2,000 pg/mL), group C (2,000~3,000 pg/mL), group D (3,000~4,000 pg/mL), and group E (≥ 4,000 pg/mL). Results: Mean E2 levels on the day of hCG administration were 3,745.3 pg/mL and mean number of retrieved oocytes were 10.1. Of 455 cycles, 148 (32.5%) cycles were clinically pregnant. Implantation rate was 12.2% and delivery rate was 18.7%. The number of obtained oocytes increased with increasing levels of serum E2. Pregnancy rate gradually increased as E2 levels increased up to the group D, but began to fall in the group E. In younger women (<38 yrs), the IVF-ET outcomes were similar to those of total patients but in older women (≥38 yrs), pregnancy rate and delivery rate were significantly higher in the group C than other groups. Conclusions: This result shows that serum E2 levels have a concentration-dependent effect on the pregnancy outcome and there is an optimal range of E2 levels to achieve for a successful pregnancy. Excessive E2 levels seem more deleterious to the pregnancy outcome in older women aged ≥38 years.
KCI
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