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이원남(Wonnam Lee),서동규(Dong-Kyu Seo),조승범(Seung-Beom Cho),선희석(Hee-Suk Sun),김기원(Ki-Won Kim),신연철(Yeon-Cheul Shin) 대한기계학회 2002 대한기계학회 춘추학술대회 Vol.2002 No.5
The stabilization of fuel-lean laminar premixed flames with the triple flame configuration has been studied experimentally using a slot burner. The presence of fuel-rich flames significantly lowers the equivalence ratio limit for stable fuel-lean flames. The stable fuel-rich/lean combustion was obtained at the over-all equivalence ratio below 0.6. The increase of fuel flow rate in fuel-rich flames makes the fuel-lean flame more stable; however, the stability of fuel-lean flames was not sensitive to the equivalence ratio of a fuel-rich flame in the range of 1.3-2.4. The similar tendency on the stable fuel-lean combustion utilizing triple flame configuration was observed for both methane and propane flames, which indicates that the fuel-rich/lean combustion can be practical for the combustion systems using natural gas or LPG as fuel.
저온 플라즈마를 이용한 디젤엔진 soot 제거에 관한 연구
채재우(J.O.Chae),황재원(J.W.Whang),김관영(K.Y.Kim),이창신(C.S.Lee),선희석(H.S.Sun),김건우(G.O.Kim) 한국자동차공학회 1998 한국자동차공학회 춘 추계 학술대회 논문집 Vol.1998 No.5_1
The importance of the elimination of air-pollution caused by the increase of energy demands is requested seriously in these days. Especially, the diesel engine exhaust gas is very harmful and difficult to reduce with current methods. The exhaust gas treatment technology using non-thermal plasma is one of the advanced method, and has advantage of high removal efficiency with low energy consumption. In this study, the experiment is carried with 1 cylinder agricultural diesel engine, and it is shown the soot removal efficiency with various engine R.P.M. and different reactor types(square-shape electrode reactor, planar-type reactor, and mixed type reactor).<br/>
만성 B형 간염과 간경변 환자에서 Lamivudine 저항성 B형 간염 바이러스의 출현양상 및 YMDD motif 돌연변이 검출
강성호,박태욱,박영민,정규원,안병민,배시현,김부성,박두호,이창돈,변병훈,최종영,신제현,차상복,선희석 대한간학회 2001 Clinical and Molecular Hepatology(대한간학회지) Vol.7 No.1
Background/Aims: Lamivudine is an antiviral nucleoside analogue effective for the treatment of hepatitis B virus (HBV) infection via the inhibition of DNA polymerase activity. The mutations, however, in YMDD motif, such as YVDD and YIDD, have been found to interfere with the therapeutic efficacy of lamivudine. This study was performed to identify the role of such mutant-type HBV among Korean hepatitis B patients with chronic hepatitis or cirrhosis receiving lamivudine treatment. Methods: Serum samples were collected from four groups of patients; patients with breakthrough (group I, n = 8); patients who showed no response after the treatment (group II, n = 6); patients who showed good response (group III, n = 6); patients with chronic hepatitis B without any treatment (group IV, n = 4). Mutations were detected by PCR-cloning and automated sequencing. Results: Mutations in YMDD were found in only 4 (50%) in group I and were negative in group II. No mutations could be identified in the serum samples collected before treatment and from groups III and IV. YVDD mutation was found to be associated with two additional mutations, 'L-to-M' in 528th amino acid and 'L-to-V' in 577th amino acid. Conclusions: Lamivudine resistance appeared in three different patterns: (1) breakthrough related to the mutations in YMDD motif; (2) breakthrough not related to the YMDD mutations; and (3) primary non-responder not related to the YMDD mutations.(Korean J Hepatol 2001;7:15-33)