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배경륜,이영수,김병규,하근진,김소연,최지용,김기식 대한심장학회 2010 Korean Circulation Journal Vol.40 No.1
Coronary embolism is an uncommon cause of myocardial infarction. A 48-year-old male presented with typical chest pain of an MI. There was no definite ST segment change on electrocardiogram (ECG) and no elevation of myocardial enzymes. Coronary angiography (CAG) revealed occlusion of the distal left anterior descending coronary artery (dLAD), the distal left circumflex coronary artery (dLCX), the diagonal branch (D) and the obtuse marginal branch (OM), with a large filling defect in the left main coronary artery (LMA) that caused the myocardial infarction. We considered the possibility that coronary embolization was caused by the migration of a thrombus in the LMA during CAG. We did balloon angioplasty in the dLAD, dLCX, OM and D and treated the patient with glycoprotein IIb/IIIa receptor antagonist. However, thrombi remained in the dLAD, OM, and dLCX. After 3 days of anti-thrombotic treatment, follow-up CAG revealed only slight resolution of thrombi in the LAD. After triple antiplatelet agent medication for 1 year, a follow-up CAG showed a resolution of the thrombi in all coronary arteries.
배경륜(Kyoung-ryun Bae),왕세명(Semyung Wang) 대한기계학회 2002 대한기계학회 춘추학술대회 Vol.2002 No.5
A reliability-based topology optimization (RBTO) using the finite element method is presented. A 2-D finite<br/> element model is constructed for topology optimization. Young’s modulus is considered as uncertain variables. In order<br/> to compute reliability constraints, two methods . RIA, PMA . are used. To find the reliability index, the limit state<br/> function is linearly approximated at each iteration. This approximation method is called as the first order reliability<br/> method (FORM), which is widely used in reliability-based design optimization (RBDO). Numerical examples show the<br/> effectiveness of the proposed method.
홍승표,이영수,배경륜,정진욱,김소연,이진배,류재근,최지용,김기식,장성국,신임희 대한심장학회 2008 Korean Circulation Journal Vol.38 No.3
Background and Objectives: Hyperuricemia is known to be a risk factor for atherosclerosis, as is gender. The variables related to metabolic syndrome (MS), as well as other cardiovascular risk factors such as serum uric acid (SUA), differ according to gender. The aim of this study was to evaluate the relationship between SUA and the variables of MS according to gender. Subjects and Methods: We randomly recruited 675 subjects (373 men and 302 women), who underwent health screening. The subjects were divided into four groups according to SUA quartiles. We compared each quartile of the SUA with the incidence of MS. The variables included body mass index (BMI), hypertension, fasting blood glucose (FBS), high-density lipoprotein (HDL) cholesterol, triglyceride (TG), and the MS score. Results: The incidence of MS in men was significantly increased compared to women, and the incidence of MS was increased according to the SUA values in women. The MS scores tended to increase according to the SUA values in both genders. The incidence of high BMI, high blood pressure, and high TG were correlated with the SUA values in both genders. However, HDL-cholesterol was correlated with MS scores in women, and fasting glucose was not correlated with MS in either gender. Conclusion: The variables of the MS might be independently associated with SUA values in both genders. In addition, the incidence of MS in women might be significantly increased according to the SUA values. However, large scale follow-up studies will be required to confirm these possibilities. (Korean Circ J 2008;38:152-160) 배경 및 목적고요산혈증은 죽상동맥 경화증의 위험인자로 알려져 있다. 다른 위험인자로 성별이 알려져 있으나 성별은 고정 인자로 작용하고 있다. 이러한 성별의 차이는 대사증후군의 인자와 혈청 요산과 같은 심혈관계 위험인자에서도 나타난다. 이에 저자들은 국내 성인 건강 검진 수진자를 대상으로 하여 혈청 요산 농도와 대사증후군발생 위험 인자들과의 상관관계를 알아보고자 하였다.방 법2006년 3월부터 2006년 6월까지 본원에서 건강검진을 받은 성인 남자 373명, 성인 여자 302명 등 총 675명을 대상으로 혈청 요산 농도를 백분위에 의거하여 4군으로 분류한 후 성별에 따라 혈청 요산 농도에 따른 대사증후군 인자와의 관련성과 대사증후군의 유병률을 판정하였다. 결 과 대사증후군의 유병률은 여성보다 남성에서 더 높았고. 혈청 요산 농도가 증가함에 따른 대사증후군의 유병률은 여성에서만 통계적으로 유의하게 상관관계가 있었다 (p=0.011). 남녀 모두에서 혈청 요산 농도가 증가함에 따라 대사증후군 정의에 해당하는 항목을 만족시키는 개수의 평균 수치가 증가함을 관찰할 수 있었다. 남녀 모두에서 혈청 요산 농도가 높아질수록 높은 체질량지수, 고혈압, 높은 중성 지방농도를 보였다. 하지만 혈청 고밀도 지단백 콜레스테롤 농도는 남성에서 보다 여성에서 더 밀접한 관계를 보였고, 공복혈당의 경우 관련성이 없었다. 결 론 대사증후군의 인자들은 남녀 모두에서 혈청 요산 농도와 독립적인 상관관계를 보였다. 대사증후군의 유병률은 여성보다 남성에서 높았으나, 혈청 요산 농도의 증가에 따른 대사증후군의 유병률은 여성에서만 통계적으로 유의한 양의 상관관계를 보였다. 그러나 이들의 인과 관계를 알기 위해서는 향후 전향적 연구가 필요할 것으로 생각된다.
공터키안(Empty sella)을 동반한 급성췌장염으로 발현된 부갑상선 선종 1예
전언주,오지혜,배경륜,장샛별,전승운,정의달,손호상,원규장 영남대학교 의과대학 2009 Yeungnam University Journal of Medicine Vol.26 No.1
The incidence of coexisting hyperparathyroidism and empty sella syndrome is rare and the etiology and incidence of their coexistence is not known. The association of hyperparathyroidism and the empty sella syndrome may be related to multiple endocrine neoplasia (MEN) syndrome due to a genetic disorder. We experienced a rare case of hyperparathyroidism presenting as acute pancreatitis combined with empty sella. We report here a 37-year old female who manifested epigastric pain because of acute pancreatitis. She had hypercalcemia due to parathyroid adenoma. A pituitary gland was not visible in the sella turcica on MRI scans. On genetic analysis, she did not show a mutation of the MENIN gene. Empty sella is thought to be a coincidental finding with hyperparathyroidism.
혈액투석 환자에서 쇄골하정맥 도관 삽입 후 쇄골에 발생한 골수염 1예
박철연 ( Chul Yun Park ),배경륜 ( Kyung Ryun Bae ),전승운 ( Seung Woon Jun ),곽진호 ( Jin Ho Kwak ),이인희 ( In Hee Lee ),안기성 ( Ki Sung Ahn ) 대한신장학회 2008 Kidney Research and Clinical Practice Vol.27 No.5
Osteomyelitis (OM) of the clavicle is a rare complication of the central venous catheterization and has been reported infrequently in the literature. We report here a case of OM of the left clavicle complicating right subclavian vein catheterization performed for hemodialysis (HD). A 41-year-old male patient on HD for 3 months complained of pain and mass over the left sternoclavicular joint. Computerized tomography showed a demarcated soft tissue mass. Bone scan demonstrated increased tracer uptake in the left clavicle compatible with OM. The patient underwent surgical exploration with removal of the necrotic bone and he was treated with antibiotics including vancomycin. Afterward he remained well on HD. In conclusion, OM should be considered in any dialysis patient who develops pain and signs of inflammation in the sternoclavicular area after central venous catheterization for HD.