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        증례 : 정상면역을 가진 성인에서 발생한 식도 방선균증 1예

        김현수 ( Hyun Soo Kim ),천종운 ( Jong Woon Cheon ),김민수 ( Min Su Kim ),정창길 ( Chang Kil Jung ),김경록 ( Kyung Rok Kim ),최재원 ( Jae Won Choi ),강동우 ( Dong Woo Kang ),김선영 ( Sun Young Kim ) 대한소화기학회 2013 대한소화기학회지 Vol.61 No.2

        Hyun Soo Kim, Jong Woon Cheon, Min Su Kim, Chang Kil Jung, Kyung Rok Kim, Jae Won Choi, Dong Woo Kang and Sun Young Kim1 Departments of Internal Medicine and Pathology1, DongKang Medical Center, Ulsan, Korea Actinomycosis is a chronic suppurative disease and caused by Actinomycosis species, principally Actinomyces israelii, which are part of the normal inhabitant on the mucous membrane of the oropharynx, gastrointestinal tract, and urogenital tract. It usually affects cervicofacial, thoracic and abdominal tissue. Cervicofacial type has the highest percentage of occurrence with 50%. Actinomycosis frequently occurs following dental extraction, jaw surgery, chronic infection or poor oral hygiene. It may also be considered as an opportunistic infection in immunocompromised patients such as malignancy, human immunodeficiency virus infection, diabetes mellitus, steroid usage or alcoholism. But, actinomycosis rarely occurs in adults with normal immunity and rare in the esophagus. We report an unusual case of esophageal actinomycosis which was developed in a patient with normal immunity and improved by therapy with intravenous penicillin G followed oral amoxicillin, and we also reviewed the associated literature.

      • KCI등재

        스카이브릿지 설치위치에 따른 고층건물의 진동제어 성능평가

        김현수,박용구,고현,이의현,이동근,Kim, Hyun-Su,Park, Yong-Koo,Ko, Hyun,Lee, Ui-Hyun,Lee, Dong-Guen 한국공간구조학회 2010 한국공간구조학회지 Vol.10 No.3

        In this study, the vibration control effect according to the installation location of the sky-bridge and the difference of natural periods of the connected buildings has been investigated. To this end, 40-story and 50-story building structures connected by a sky-bridge were used as example structures and the equivalent modeling method was used. Boundary nonlinear time history analyses were performed using El Centro and Taft earthquakes to investigate the dynamic behavior of the example structures and vibration control effect of the sky-bridge. Based on numerical results, it has been shown that displacement responses can be effectively controlled as the installation floor of the sky-bridge increases and acceleration responses can be effectively reduced when the sky-bridge is installed on the mid-stories of the example building. 본 연구에서는 스카이브릿지 설치위치 및 연결된 구조물의 고유진동주기 차이에 따른 전체 구조물의 진동제어 효과를 분석하였다. 이를 위하여 스카이브릿지로 연결된 40층과 50층 구조물을 예제 구조물로 사용하였고, 등가모형화기법을 이용하여 예제 모델을 구성하였다. El Centro 및 Taft 지진을 사용하여 경계비선형 시간이력해석을 수행하였고 구조물의 동적거동과 진동제어 효과를 분석하였다. 해석결과 변위응답은 스카이브릿지를 상부층에 설치할수록 더 효과적으로 제어할 수 있었고 가속도응답은 구조물의 중간층부근에 설치할 때 더 효과적으로 저감시킬 수 있었다.

      • KCI등재후보

        Rat periodontal ligament cell에서의 RANKL mRNA의 발현

        김현수,정현주,김영준,김옥수,Kim, Hyun-Soo,Chung, Hyun-Ju,Kim, Young-Joon,Kim, Ok-Su 대한치주과학회 2004 Journal of Periodontal & Implant Science Vol.34 No.2

        As the periodontal ligament cells show similar phenotype with osteoblasts, periodontal ligament cells are thought to play an important role in alveolar bone remodeling. According to recent studies, receptor activation of nuclear factor $^{\kappa}B$ ligand (RANKL) and osteoprotegerin (OPG) are expressed in periodontal ligament cells during tooth movement. Also periodontal ligament cells is known to play an important role in the progression of periodontal disease. This study was designed how the expression of RANKL and OPG in periodontal ligament cells was regulated by IL-1 ${\beta}in$ the concentration of $0.01{\sim}10$ ng/ml. The results are as follows; 1. Periodontal ligament cells which stimulated by 1L-1 ${\beta}$ increased soluble RANKL synthesis by dose-dependent pattern in the concentration of $0.01{\sim}10$ ng/ml. 2. 1L-1 ${\beta}$ induced mRANKL expression in dose-dependent manner in the concentration of $0.01{\sim}5$ ng/ml. 3. mOPG expression was not to be influenced by 1L-1 ${\beta}$. These results suggested that rat periodontal ligament cells could regulate osteoclastogenesis by stimulation of production of RANKL.

      • KCI등재

        초대형 골조시스템 전용 전후처리 및 해석프로그램의 개발

        김현수,이동근,Kim Hyun-Su,Lee Dong-Guen 한국전산구조공학회 2006 한국전산구조공학회논문집 Vol.19 No.3

        근래에 들어서 사회적 및 경제적인 요구에 의하여 건축구조물이 점차 고층화 및 대형화됨에 따라서 다양한 형식의 구조시스템이 연구 및 개발되고 있다. 비교적 최근에 개발된 초대형 골조시스템은 초대형부재의 조합으로 횡방향 강성을 충분히 발휘함으로써 초고층건물에 적합한 구조시스템으로 인식되고 있다. 그러나 이러한 초대형 골조시스템을 적용한 건물의 거동을 예측하기 위해서는 매우 많은 수의 절점과 요소로 이루어진 유한요소 모델을 해석해야 하므로 상당한 양의 해석시간과 엔지니어의 노력이 필요하게 된다. 따라서 본 연구에서는 초대형 골조시스템 전용 해석프로그램을 개발하여 초대형 골조구조물의 해석과 설계에 소요되는 시간과 노력을 줄이고자 한다. 이를 위하여 초대형 골조구조물의 특징을 활용한 효율적인 모형화기법과 행렬응축기법을 사용하여 해석에 사용되는 자유도수를 최소화도록 만든 해석모델이 개발되었다. 예제구조물의 해석을 수행하여 본 연구에서 개발된 프로그램을 사용한 결과와 일반적인 해석방법에 의한 결과와 비교함으로써 개발된 프로그램의 효율성과 정확성을 검증하였다. Recently, various types of structural systems for skyscrapers are studied as the height and size of the building structures rapidly increase due to social and economical needs. The mega frame system among them, which is the structural system developed recently, is known as a suitable structural system for skyscrapers because this structural system has sufficient stiffness against the lateral forces by combination of mega members which consist of many columns and girders. Since the mega frame structure has significant numbers of elements and nodes, it takes tremendous times and computer memories to analyze and design the structures. Therefore, the exclusive structural analysis program for mega frame system is developed to reduce the efforts and time required for the analysis and design of mega frame structure. To this end, an efficient modelling technique using the characteristics of mega frame structures and an efficient analytical model, which uses a few DOFs selected by the user using the matrix condensation method, are developed in this study. Static and dynamic analyses are conducted using an example structure. The effectiveness and accuracy of the developed program we verified by the comparison between the results of the proposed method and the conventional method.

      • KCI등재

        경사진 고층건물의 진화최적화 알고리즘에 기반한 지진응답 제어

        김현수,강주원,Kim, Hyun-Su,Kang, Joo-Won 한국공간구조학회 2021 한국공간구조학회지 Vol.21 No.3

        A tilted tall building is actively constructed as landmark structures around world to date. Because lateral displacement responses of a tilted tall building occurs even by its self-weight, reduction of seismic responses is very important to ensure structural safety. In this study, a smart tuned mass damper (STMD) was applied to the example tilted tall building and its seismic response control performance was investigated. The STMD was composed of magnetorheological (MR) damper and it was installed on the top floor of the example building. Control performance of the STMD mainly depends on the control algorithn. Fuzzy logic controller (FLC) was selected as a control algorithm for the STMD. Because composing fuzzy rules and tuning membership functions of FLC are difficult task, evolutionary optimization algorithm (EOA) was used to develop the FLC. After numerical simulations, it has been seen that the STMD controlled by the EOA-optimized FLC can effectively reduce seismic responses fo the tilted tall building.

      • KCI등재

        용담호 조류군집의 시공간적 분포와 조류발생 요인분석

        김현수,정일환,Kim, Hyun-su,Jeong, Il-hwan 한국지하수토양환경학회 2015 지하수토양환경 Vol.20 No.7

        Spatial and temporal changes in algal population in Yongdam reservoir and ecological factors that induced the changes in the size and composition of algal population were investigated by monthly sampling at ten locations in the reservoir. Nutritional state of the reservoir was identified to be phosphorus-limited with nitrogen to phosphorus (N : P) ratio much greater than 17 in most samples. Algal population was dominated by three taxonomic groups, diatoms, chlorophytes and cyanobacteria. Although explosive algal growth was not observed in the summer, algal population showed transition with time of the dominant algal type from diatoms in the winter to cyanobacteria in the summer. Chlorophyta was not the dominant group in the reservoir although they maintained relatively stable number of cells in the reservoir and showed increase in population from March to May. The application of statistical methods revealed that the factors inducing changes in cell number of each group were water temperature for diatoms and cyanobacteria and phosphorus concentration for chlorophyte. Fluctuation of cyanobacterial population was mainly observed near the inlet of tributaries while diatoms showed higher variation inside the reservoir.

      • KCI등재

        동해 연근해에서 위상 추정기를 갖는 적응형 등화기의 실험적 성능 검증

        김현수,최동현,서종필,정재학,김성일,Kim, Hyeon-Su,Choi, Dong-Hyun,Seo, Jong-Pil,Chung, Jae-Hak,Kim, Seong-Il 한국음향학회 2010 韓國音響學會誌 Vol.29 No.4

        위상동기식 변조기법은 주파수 대역폭의 효율과 전송 신뢰도를 높일 수 있으나 수중 채널의 시변 다중경로에 의해 인접 심볼간 간섭이 발생되어 수중통신에 적용하는 데 어려움이 있다. 본 논문에서는 동해 연근해에서 위상동기 변조방식인 BPSK와 QPSK 신호를 전송하고, 시간에 따라 변화하는 다중경로와 위상변동에 의해 왜곡된 수신신호를 보상하기 위한 위상 추정기를 결합한 적응형 등화기를 제안한다. 해상실험을 통해 전송된 위상동기식 변조신호가 수중채널의 시변 다중경로 특성에 의해 왜곡되었음을 보였고 제안된 방법에 의해 왜곡된 신호가 보정됨을 보였다. BPSK와 QPSK 신호 전송시 300 m 거리에서 각각 0.0078, 0.0376의 비트 오류율을 보였으며, 1000 m 거리에서는 0.0146, 0.0293의 비트 오류율을 보였다. Phase coherent modulation techniques in underwater acoustic channel can improve bandwidth efficiency and data reliability, but they are made difficult by time-varying intersymbol interference. This paper proposes an adaptive equalizer combined with phase estimator which compensates distortions caused by time-varying multipath and phase variation. The experiment in the East sea demonstrates phase coherent signals are distorted by time-varying multipath propagation and the proposed scheme equalizes them. Bit error rate of BPSK and QPSK are 0.0078 and 0.0376 at 300 meter horizontal distance and 0.0146 and 0.0293 at 1000 meter respectively.

      • KCI등재

        적응형 스마트 공유 TMD의 MIMO 제어알고리즘개발

        김현수,강주원,Kim, Hyun-Su,Kang, Joo-Won 한국공간구조학회 2015 한국공간구조학회지 Vol.15 No.2

        A shared tuned mass damper (STMD) was proposed in previous research for reduction of dynamic responses of the adjacent buildings subjected to earthquake loads. A single STMD can provide similar control performance in comparison with two traditional TMDs. In previous research, a passive damper was used to connect the STMD with adjacent buildings. In this study, a smart magnetorheological (MR) damper was used instead of a passive damper to compose an adaptive smart STMD (ASTMD). Control performance of the ASTMD was investigated by numerical analyses. For this purpose, two 8-story buildings were used as example structures. Multi-input multi-output (MIMO) fuzzy logic controller (FLC) was used to control the command voltages sent to two MR dampers. The MIMO FLC was optimized by a multi-objective genetic algorithm. Numerical analyses showed that the ASTMD can effectively control dynamic responses of adjacent buildings subjected to earthquake excitations in comparison with a passive STMD.

      • KCI등재

        일방향 중공슬래브의 휨강도 산정방법에 관한 연구

        김현수,임준호,강주원,Kim, Hyun-Su,Lim, Jun-Ho,Kang, Joo-Won 한국전산구조공학회 2012 한국전산구조공학회논문집 Vol.25 No.6

        중공슬래브 시스템은 슬래브 두께가 증가해도 자중은 크게 증가하지 않고, 일반슬래브에 비해서 휨성능이 크게 저하되지 않는 장점이 있다. 이러한 경제적인 건물 설계 및 친환경 구조물 구현을 가능하게 하는 시스템에도 불구하고 중공슬래브의 활용도는 현재로서는 낮다고 할 수 있다. 특히 국내의 건축분야에 있어서는 매우 낮은 편이다. 이러한 현 상황의 가장 큰 이유는 중공슬래브의 적용을 위한 구조 해석 및 설계방법이 일반화되어 있지 않다는 것이다. 본 연구에서는 실질적인 압축영역을 고려하기 위해 가정한 중공 단면형상에서 중립축 위치에 따른 압축응력블럭의 체적으로 휨강도 산정식을 제시하였다. 기존 중공부 상부만을 압축영역으로 고려한 휨강도 산정방법은 가장 보수적인 방법으로 판단되며 2개의 대체단면을 설정하여 휨내력을 산정하는 것이 더 실질적인 방법으로 판단된다. The hollow slab has advantages that its self-weight does not greatly increase notwithstanding the increase of its thickness and its flexural performance does not significantly degrade in comparison with general reinforced concrete slab. However, the utilization of the hollow slab is currently being underestimated in spite of structural system that enables economic design of building and construction of eco-friendly structure. the significant reasons for this situation is that the method of structural analysis and design for hollow slab is not generalized. In this study, to consider practical compressive zone of hollow slab, the equation for its flexural strength is proposed by the volume of compressive stress block according to neutral axis location in hollow section assumed. Existing estimation method of flexural strength of hollow slab considering only compressive zone above hollow part is evaluated as the most conservative method and the method estimating flexural strength by two alternative cross-section of hollow slab is evaluated as more practical method.

      • KCI등재

        스마트 TMD의 최적설계를 위한 파라메터 연구

        김현수,강주원,Kim, Hyun-Su,Kang, Joo-Won 한국공간구조학회 2017 한국공간구조학회지 Vol.17 No.4

        A smart tuned mass damper (TMD) was developed to provide better control performance than a passive TMD for reduction of earthquake induced-responses. Because a passive TMD was developed decades ago, optimal design methods for structural parameters of a TMD, such as damping constant and stiffness, have been developed already. However, studies of optimal design method for structural parameters of a smart TMD were little performed to date. Therefore, parameter studies of structural properties of a smart TMD were conducted in this paper to develop optimal design method of a smart TMD under seismic excitation. A retractable-roof spatial structure was used as an example structure. Because dynamic characteristics of a retractable-roof spatial structure is changed based on opened or closed roof condition, control performance of smart TMD under off-tuning was investigated. Because mass ratio of TMD and smart TMD mainly affect control performance, variation of control performance due to mass ratio was investigated. Parameter studies of structural properties of a smart TMD was performed to find optimal damping constant and stiffness and it was compared with the results of optimal passive TMD design method. The design process developed in this study is expected to be used for preliminary design of a smart TMD for a retractable-roof spatial structure.

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