공황 장애 환자의 인지-행동 치료 1례

강동우,최영희,이정흠,정영조,Kang, Dong-Woo,Choi, Young-Hee,Lee, Jung-Hum,Chung, Young-Cho 한국정신신체의학회 1996 정신신체의학 Vol.4 No.2

In spite of its prominent effects on reduction of panic attacks and preveniton of relapse, cognitive-behavioral therapy(CBT) for panic disorder is seldomly utilized and studied in this country. for the past year, authors have modified CBT program for panic disorder that was based on PCT(panic control program) designed by Dr. Barlow and Dr. Craske. Our program is composed of informational component, somatic management skills, cognitive restructuring, interoceptive exposure and in vivo exposure. One patient has significantly improved by this program and satisfied with the treatment result. The aim of this article is to present our experience of treating a panic patient with CBT.

Mossbauer 효과에 의한 제주도 찰흙의 함철 광물의 열적 거동과 상변환에 관한 연구

강동우,김두철,류재연,고정대,홍성락,송관철 ( Dong Woo Kang,Doo Chul Kim,Jai Yon Ryu,Jeong Dae Ko,Sung Rak Hong,Kwan Cheol Song ) 한국광물학회 1997 광물과 암석 (J.Miner.Soc.Korea) Vol.10 No.2

수도권의 주택점유 특성 변화로 분석한 슈바베의 가설

강동우,이성우,김현중,Kang, Dong-Woo,Lee, Seong-Woo,Kim, Hyun-Joong 한국토지주택공사 토지주택연구원 2012 LHI journal of land, housing, and urban affairs Vol.3 No.1

본 연구는 1990년 이후 인구 및 사회경제적으로 고도화된 경제발전의 특징을 보이는 수도권의 주택점유 특성변화를 분석하기 위해서 슈바베의 가설을 검정하였다. 슈바베의 가설은 한 나라의 경제발전에 따라 주택수요를 결정하는 요인이 사회경제적 요인 보다는 인구학적 요인으로 옮겨갈 것이라는 것이다. 슈바베의 가설을 검정하기 위해 본 연구에서는 1980년부터 2005년까지 통계청에서 제공하는 인구주택총조사 자료를 이용하여 약 25년동안 노정된 수도권 자가소유에 대한 수요 변화의 특성을 분석하였다. 본 연구에서는 Binary probit모형과 Blinder-Oaxaca 해체기법을 응용하였으며, 연구결과는 두 가지 연구가설이 성립하는 것으로 나타났다. 자가소유로 측정한 주택수요변화의 경우 사회경제적 요인보다는 인구학적 변화의 영향력이 1980년대 이후 지속적으로 증대되어 온 것으로 드러났다. 요약하면, 수도권 주택시장의 경우 주택점유에 있어서 가구의 경제적 능력보다는 인구학적 특성변화에 따른 주택소비 구입의사의 중요성이 점차 증대되고 있는 것으로 나타나 슈바베의 가설이 유효함을 보여주고 있다. The Schwabe's law explains the housing demand weighs more on demographic factors rather than on socio-economic factors as societies achieve higher level of economic development. Based on Schwabe's law, the present study constructs a hypotheses to analyze changes of housing demand with respect to housing tenure change in Seoul Metropolitan Area (SMA) during the periods of 1980 to 2005. To test the hypotheses, the authors take advantage of the Population and Housing Census 2% data from 1980 to 2005. The authors apply binary probit with decomposition method to verify our hypotheses. The authors found that the influence of socio-economic factors on housing tenure have been weakened in the housing market during the periods of 1980 to 2005. On the other hand, the relative influence of demographic factors have been strengthened in the housing market during the periods. The present study concludes that housing demand in the SMA have been dramatically changed from socio-economic characteristics to demographic factors to decide housing tenure during the periods, which confirms the hypotheses of the present study.

멀티프라이머리 디스플레이를 위한 3D-LUT 색 신호 분리 방법

강동우,조양호,김윤태,최원희,하영호,Kang Dong-Woo,Cho Yang-Ho,Kim Yun-Tae,Choe Won-Hee,Ha Yeong-Ho 대한전자공학회 2005 電子工學會論文誌-SP (Signal processing) Vol.42 No.6

본 논문에서는 멀티 프라이머리 디스플레이(multi-primary display; MPD)에서 색 재현을 위해 선형 LAB 색공간에서 3차원 took-up-table(3D-LUT)을 이용한 색신호 분리방법을 제안한다. 제안한 방법은 인간 지각의 3가지 속성을 반영하는 선형 LAB 색공간에서 작성된 MPD 색역의 경계를 적은 용량의 메모리를 가지는 3D-LUT로 작성한다. 이때 색역 경계점의 자극치와 MPD의 색신호의 선형관계를 이용하여 3D-LUT에는 휘도 및 색상에 대한 채도와 색신호 조합이 저장된다. 작성된 3D-LUT에 기반하여 입력 자극치에 대응하는 MPD 색신호를 주변 색역 경계점의 색신호 변화를 고려하여 색역 경계점과 입력의 채도비로 보간한다. 그 결과, MPD 색신호가 연속적 계조를 가지도록 하였다. 또한 선형 LAB 색공간에서 색역 경계 LUT를 사용하여 연산의 복잡도를 감소시키고 MPD의 부드러운 색신호 변화를 유도하였다. This paper proposes the color decomposition method for multi-primary display (MPD) using a 3-dimensional look-up-table (3D-LUT) in a linearized LAB space. The proposed method decomposes conventional three-primary colors into the multi-primary control values of a display device under constraints of tristimulus match. To reproduce images on the MPD, the color signals should be estimated from a device-independent color space, such as CIEXYZ and CIELAB. In this paper, the linearized LAB space is used due to its linearity and additivity in color conversion. The proposed method constructs the 3-D LUT, which contain gamut boundary information to calculate color signals of the MPD. For the image reproduction, standard RGB or CIEXYZ is transformed to the linearized LAB and then hue and chroma are computed to refer to the 3D-LUT. In the linearlized LAB space, the color signals of a gamut boundary point with the same lightness and hue of an input point are calculated. Also, color signals of a point on gray axis are calculated with the same lightness of an input. With gamut boundary points and input point, color signals of the input points are obtained with the chroma ratio divided by the chroma of the gamut boundary point. Specially, for the hue change, neighboring boundary points are employed. As a result the proposed method guarantees the continuity of color signals and computational efficiency, and requires less amount of memory.

뇌파의 임상적 유용성 : 뇌파소견과 뇌전산화 단층촬영 검사 및 뇌자기공명 영상검사 소견을 비교하여

강동우,이영호,최영희,정영조,Kang, Dong-Woo,Lee, Young-Ho,Choi, Young-Hee,Chung, Young-Cho 대한수면의학회 1996 수면·정신생리 Vol.3 No.2

To demonstrate the clinical usefulness of electroencephalography (EEG) and factors increasing the usefulness of EEG, the authors evaluated each relationship between EEG related factors and clinical variables, and neuroimaging studies (CT and MRI)-related factors, and factors which are related with routine neurological examination for 207 patients who had been evaluated with both of EEG and neuroimaging study(CT or/and MRI). The results were as follows: 1) Abnormality of EEG findings had significant relationships with chief complaints, diagnosis, medication use, seizure attack, pathological reflex, and level of consciousness. However there were no significant correlations between abnormality of EEG findings and neuroimaging studies (CT and MRI)- related factors. 2) Laterality of EEG findings had significant relationships with abnormality, laterality, and focality of CT findings, and also with abnormality of MRI findings. But there were no significant correlations between laterality of EEG findings and clinical variables, and neurological examination-related factors. 3) Anterior-posterior distribution of EEG findings was significantly related with medication use. 4) Focality of EEG findings had significant relationships with sex, sensory dysfunction sign, and cerebellar dysfunction sign. But there were no significant correlations between focality of EEG findings and neuroimaging studies(CT and MRI) related factors. 5) Abnormal EEG pattern had significant correlations with various factors, such as age, chief complaints, duration from onset of symptom to taking MRI, seizure attack, abnormality and nature of lesion in CT findings, cortical atrophy in MRI findings, motor dysfunction sign, sensory dysfunction sign, and pathological reflex. 6) With abnormality on sleep activation, age, age of onset, seizure attack, ventricular enlargement in CT findings, and abnormality of MRI findings were significantly correlated. 7) With abnormality on hyperventilation activation, duration of illness and laterality of MRI findings were significantly correlated. Above results may suggest that abnormality of EEG findings is more closely related with functional change of the brain than structural changes of the brain and laterality of EEG findings is vice versa. And also that medication use has an influence on anterior versus posterior distribution of EEG findings and focality of EEG findings is not related with structural changes of the brain. Activation with sleep may be effective to show age differences and provocation of seizure activity and hyperventilation may be effective to detect the abnormal EEG findings by cerebrovascular insufficiency.

도시형 한옥의 리모델링을 통한 공공건축물 활용 가능성 연구

강동우(Kang, Dong-Woo),김민규(Kim, Min-Gyu),김도경(Kim Do-Kyung) 대한건축학회 2015 대한건축학회논문집 Vol.31 No.10

Hanok which is the traditional residence style of Korea has been existing for a long time. Recently, Hanok is being actively used through the newly-built building and remodeling for the residence purpose. However, few public buildings which follow the traditional Korea Architecture are founded. This Study is specialized in utilization of traditional Korea architecture building using as a public building. Hyehwa-dong community service center is nominated one of the suitable case. Hyehwa-dong community service center, as a case of the study, shows the positive possibilities of utilization of urban Hanok. Also, Hyehwa-dong community service center makes use of the historicity and Identity of Hyehwa-dong by Remodeling of the existing residence urban Hanok. This study has been performed through observation method and survey method investigation for the user of Hyehwa-dong community service center. The investigation result shows that users of Hyehwa-dong community service center feel inconvenience because of lack of enough inner space comparing other general public center. Even though the center has not enough space, the users want the building to be used as a public center because the building has the close relationship between traditional exterior space and interior space. Based on the investigation result, remodeling of the existing Hanok as a public building has positive potential as well as this dissertation is able to be used as not only a reference but also invigorating the Hanok.

실리콘 기반의 고주파 위상 배열 시스템에 관한 연구

강동우(Dong-Woo Kang) 한국전자파학회 2014 한국전자파학회논문지 Vol.25 No.1

본 논문에서는 최근 실리콘 기반의 소자를 이용하여 microwave 대역에서 millimeter wave 대역까지 동작하는 위상배열 시스템 개발에 관한 연구를 리뷰하고자 한다. 우선 위상 배열 시스템의 중요한 부품인 위상 변위기를 CMOS 공정을 이용한 설계 방법에 대해 논의한다. 그리고 수동형 위상 변위기를 송수신 모듈에 적용하여 한 채널에서 16 채널까지 확장하여 실리콘 칩에 구현을 하였다. 35 ㎓ 대역에서 동작하는 4 채널 송수신 칩은 200 ㎽ 이하의 저전력 성능을 보여주었다. 또한, 44 ㎓ 대역에서 16 channel로 확장하여 송신 출력과 선형성을 향상시킬 수 있었다. 능동형 위상 변위기는 Ku band 대역에서 동작하는 2-antenna 4-beam 수신기에 적용하였다. 한 칩에서 4개의 서로 다른 방향의 신호가 존재함으로 신호 간의 커플링을 최소화 하는 방법을 소개하고, 이를 측정을 통해 검증하였다. This paper reviews the research on silicon based phased array system operating from microwave to millimeter wave frequencies. First, the design of phase shifter using CMOS technology is presented. The passive phase shifter is applied to the transmit/receive module from one to 16 channel in a single chip. The 35 ㎓ 4-element T/R module consumes less than 200 ㎽ both transmit and receive modes. The architecture can extend to 16-channel operating at 44 ㎓, thereby improving transmit power and linearity. The Ku-band 2-antenna 4-element receiver was developed using active phase shifter based on vector sum method. It is important to minimize coupling between beams because the chip contains four independent beams. The method of coupling is presented and verified.

Fuzzy Control System에서 효과적인 비퍼지화 방법에 관한 연구

강동우(Dong Woo Kang),이상배(Sang Bae Lee) 한국지능시스템학회 1994 한국지능시스템학회 학술발표 논문집 Vol.- No.-

Thrichoderma atroviride 배양액의 tyrosinase 억제제에 관한 연구

강동우(Dong Woo Kang),김규민(Kyu-Min Kim),김예성(Ye-Seong Kim),서유진(Yu-Jin Seo),송다영(Da-Yeong Song),오다윤(Da-Yun Oh),최시온(Si-On Choi),황주현(Ju-Hyeon Hwang),김삼웅(Sam Woong Kim),방규호(Kyu Ho Bang),갈상완(Sang Wan Gal) 한국생명과학회 2021 생명과학회지 Vol.31 No.1

현대인에게 미백화장품은 미를 나타내는 중요한 요소이다. 균류는 미백에 연관된 다양한 물질대사산물을 생산한다. 본 연구에서 미백기능성 화장품에 소재를 탐색하기 위해 Trichoderma atroviride 배양액에 물질대사산물에 의한 tyrosinase inhibitors를 조사하였다. 또한, 억제 효과는 식의약안전처에 미백화장품 원료로 승인된 알부틴과 비교하였다. T. atroviride 배양액에 물질대사산물은 알부틴의 활성보다 높은 tyrosinase 억제 활성을 보였다. T. atroviride 배양액에 포함된 tyrosinase inhibitors 중 일부는 열에 안정한 반면에, 일부는 열에 불안정하였다. 본 물질들은 약산성~중성 pH 영역에서는 안정하였지만, 그 외 영역에서는 매우 불안정하였다. Proteinase K에 의해 활성 영향이 거의 없었기 때문에 inhibitor들은 대부분 물질대사산물로 구성된 것으로 추정된다. 따라서 본 T. atroviride 배양액에 물질대사산물은 미백화장품 소재로써 잠재적 가치가 있는 것으로 제의된다. In today’s society, functional whitening cosmetics are important to beauty. Fungi are known to produce a variety of whitening-related metabolites. In this study, we searched for tyrosinase inhibitors with metabolic products derived from Trichoderma atroviride supernatant in order to apply a material for whitening functional cosmetics. In addition, the inhibitory effect was compared to arbutin, which has already been approved as a whitening raw material by the Korea Ministry of Food and Drug Safety (KMFDS). The metabolites from the T. atroviride supernatant showed higher tyrosinase inhibitory activity than that of arbutin. Some of the tyrosinase inhibitors were stable to heat, whereas some were unstable. The heat unstable material was exhibited in the case of samples treated with little amounts, such as 0.02~0.2%. They were very unstable in acidic and alkali pHs, especially under acidic conditions. However, it was found that a weakly-acidic to neutral pH range was the optimal working pH, especially neutral pH. Since the activity of the inhibitory substances in the T. atroviride supernatant was maintained regardless of proteinase K treatment, it was assumed that the metabolites, but not the bioactive peptides, were involved in the activity. In summary, we propose that the metabolites derived from T. atroviride supernatant have strong potential as whitening raw material.

Trichoderma viridescens SW-1 미백 기능성소재의 생화학적 특성

강동우(Dong Woo Kang),김판길(Pan Gil Kim),김삼웅(Sam Woong Kim),방규호(Kyu Ho Bang),김철호(Chul Ho Kim),이상원(Sang Won Lee),갈상완(Sang Wan Gal) 한국생명과학회 2021 생명과학회지 Vol.31 No.7

최근 기능성 화장품 시장의 증가와 더불어 안전성과 기능성을 가진 제품에 대한 소비자들의 요구가 증대됨에 따라 안전성, 기능성, 안정성을 가진 새로운 기능성 화장품 소재의 개발 필요성이 대두 되고 있다. 본 연구에서는 야생 버섯에 자생하는 균류에 대하여 tyrosinase 저해 활성 및 항산화 활성에 대하여 우수한 기능성을 가지는 균주를 선발 하였으며, 선발된 균주를 동정 후 T. viridescens SW-1으로 명명하였다. 배양 기간별 tyrosinase 저해 활성을 측정한 결과 3일차에서 가장 강한 활성을 나타내었으며, 3일차 배양 상등액을 이용하여 농도별 활성을 측정한 결과 상등액 5% 이상 처리시 94% 이상의 저해활성을 유지하는 것으로 확인 되었다. 상등액을 온도별 처리 후 저해율을 확인한 결과 tyrosinase 저해 활성이 유지되었으며 이에 따라 우수한 열 안정성을 확인 하였다. 세포생존율 측정 결과 10% 상등액 처리시까지 세포 독성이 나타나지 않았으며 세포에서의 멜라닌 함량 조사 결과 10% 상등액 처리시 세포내 27.1%, 세포외 7.5%의 저해율을 확인하였다. 본 연구에서 T. viridescens SW-1 배양 상등액의 세포독성 및 항균, 멜라닌 합성 저해 등의 기능성, 열처리 후 tyrosinase 저해활성 확인을 통한 열 안정성을 확인 하였다. 따라서 T. viridescens SW-1 배양 상등액을 활용한 미백기능성 원료로써 활용 가능성이 높기 때문에 향후 산업화를 위한 연구가 수행되어야 할 것이다. In this study, in order to isolate excellent whitening agents from fungal cultural broth, various fungi were collected from wild areas in South Korea and then screened for tyrosinase inhibition activity, as tyrosinase is a precursor for the biosynthesis of melanin in regulating skin color. A fungus strain that inhibits tyrosinase activity has been identified and confirmed as Trichoderma viridescens (later renamed T. viridescens SW-1) via ITS sequencing. In T. viridescens SW-1, tyrosinase inhibitory activity was strongest on day three of culture. A 5% culture broth showed a tyrosinase inhibitory activity greater than 90% and exhibited high thermostability on day three. At 10% culture broth, the accumulations of intra- and extracellular melanin were inhibited above 27.1% and 7.5%, respectively. In summary, the physical and functional properties of the tyrosinase inhibitory substances of T. viridescens SW-1 included high levels of inhibition of melanin synthesis and antioxidative activity as well as thermostability. Therefore, we suggest that the whitening substance identified from the cultural broth of T. viridescens SW-1 has potential for application as a functional cosmetic ingredient.