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      • 2004 상반기 부산 지역에서 유행한 인플루엔자의 임상 역학적 분석 및 인플루엔자 진단에 있어서의 신속 항원 검사법

        최소영,이나영,김성미,김길현,정진화,최임정,조경순,Choi, So Young,Lee, Na Young,Kim, Sung Mi,Kim, Gil Heun,Jung, Jin Hwa,Choi, Im Jung,Cho, Kyung Soon 대한소아감염학회 2004 Pediatric Infection and Vaccine Vol.11 No.2

        목 적 : 인플루엔자는 매년 전 세계적인 유행을 일으키는 급성 호흡기 질환으로 높은 이환율과 사망률을 보이나 국내에서는 진단법에 있어 임상 진단에 의존하고 있는 실정이다. 본 저자들은 2004년 상반기 부산 지역에서의 인플루엔자의 역학적 특성과 임상 양상 및 인플루엔자의 진단에 있어서 신속 항원 검사법인 QuickVue 인플루엔자 테스트의 유용성에 대하여 연구하여 인플루엔자 감시 및 진단, 치료에 있어서 기초 자료를 제공하고자 한다. 방 법 : 2004년 1월부터 6월까지 부산 메리놀병원 외래, 입원 및 응급실 방문 환아 중 인플루엔자 바이러스 감염이 의심이 되는 환아의 발병 시기, QuickVue 인플루엔자 테스트의 결과 및 인플루엔자 바이러스 배양 결과와 인플루엔자 바이러스가 배양된 환아들의 발병 시기, 성별, 연령, 임상진단, 임상 양상, 검사 소견, 인플루엔자 예방 접종 유무, QuickVue 인플루엔자 테스트 결과 및 치료 경과에 대하여 후향적으로 조사, 분석하였다. 결 과 : 1) 연구 기간 중 621명의 인플루엔자 의심 환아 중 QuikcVue 인플루엔자 테스트 양성은 181례(29.1%), 인플루엔자 바이러스 배양 양성은 79례(12.7%)이었다. 2) QuickVue 인플루엔자 테스트 양성 181례 중 74례(40.8%)에서 인플루엔자 바이러스가 배양되었고 QuickVue 인플루엔자 테스트 음성 440례 중 5례(1.1%)에서 인플루엔자 바이러스가 배양되었다. 3) 인플루엔자 바이러스가 분리된 환아들 중 A형 인플루엔자가 65례(82.2%), B형 인플루엔자가 14례(17.7%)이었다. 4) 인플루엔자 의심 환아 621명의 발병 월별 분포는 2004년 1월 32례(5.1%), 2월 67례(10.8%), 3월 298례(47.9%), 4월 204례(32.8%), 5월 14례(2.2%), 6월 6례(0.9%)로 3, 4월까지 집중적으로 발생하였고 인플루엔자 바이러스가 분리된 79명의 발병 월별 분포는 3월 49명(62%), 4월 30명(37.9%)이었다. 5) 인플루엔자 바이러스가 분리된 79명 중 남아가 44명(55.6%), 여아가 35명(44.3%)으로 남녀 성비는 1.2 : 1로 남아가 더 많았다. 6) 인플루엔자 바이러스가 분리된 79명의 환아들의 중앙연령은 4년 6개월(11개월~16세) 이었고, A형은 4세 7개월(11개월~16세), B형은 5세 9개월(13개월~14세)로 A형이 B형보다 중앙 연령이 낮았다. 7) 인플루엔자 바이러스가 분리된 환아들의 임상진단은 기관지염이 27례(34.1%)로 가장 많았고, 폐렴 21례(25.3%), 합병증을 동반하지 않은 인플루엔자 18례(22.7%), 급성 중이염14례(17.7%), 크룹 5례(6.3%), 천식악화 3례(3.7%), 부비동염 1례(1.2%), 열성 경련 1례(1.2%)순이었으며 2가지 이상의 진단명을 가진 경우도 흔하였다. 8) 인플루엔자 바이러스가 분리된 환아들의 임상양상으로는 발열이 79명(100%)의 환자에서 나타났고 기침은 71명(89.8%)에서 나타났고 그 외 흔한 증상은 비루 71명(89.8%), 인두통 48명(60.7%), 두통 38명(48.1%), 오한 36명(45.5%), 근육통 30명(37.9%), 소화불량 28명(35.4%), 복통 19명(24.0%), 설사 16명(20.2%), 구토 5명(6.3%), 경련 2명(2.5%)순으로 나타났다. 9) 인플루엔자 바이러스가 분리된 환아들의 진찰 소견으로는 인두 발적 70명(88.6%), 편도 비대 41명(51.8%), 건성 수포음 26명(32.9%), 수포음 8명(10.1%), 고막 충혈 8명(10.1%), 결막 충혈 5명(6.3%), 천명 3명(3.7%), 협착음이 3명(3.7%)에서 동반되었다. 결 론 : 인플루엔자는 매년 겨울과 봄에 유행하는 소아 호흡기 감염의 중요한 원인으로 소아의 건강상에 많은 영향을 끼치고 있으므로 적절한 예방, 진단, 치료가 필수적이다. 인플루엔자의 진단에는 보편적으로 임상적 진단과 바이러스 배양법이 사용 Purpose : Although influenza is one of the most important cause of acute respiratory tract infections in children, virus isolation is not popular and there are only a few clinical studies on influenza and diagnostic methods. We evaluated the epidemiological and clinical features of influenza in children and rapid antigen detection test(QuickVue influenza test) on fist half of the year 2004 in Busan. Methods : From January 2004 to June 2004, throat swab and nasal secretion were obtained and cultured for the isolation of influenza virus and tested by rapid antigen detection test(QuickVue influenza test) in children with suspected influenza infections. The medical records of patients with influenza virus infection were reviewed retrospectively. Results : Influenza viruses were isolated in 79(17.2%) out of 621 patients examined. Influenza virus was isolated mainly from March to April 2004. The ratio of male and female with influenza virus infection was 1.2 : 1 with median age of 4 years 6month. The most common clinical diagnosis of influenza virus infection was bronchitis. There was no difference between influenza A and B infection in clinical diagnosis and symptoms. All patients recovered without severe complication. The sensitivity obtained for rapid antigen detection test (QuickVue influenza test) was 93.6% and the specificity was 80.2%, the positive predictive value 40.8%, the negative predictive value 98.8%. Conclusion : With rapid antigen detection test, it is possible early detection of influenza in children. reduction in use of antimicrobial agent and early use of antiviral agent.

      • KCI등재

        대구지역 여대생의 거주형태에 따른 식사 행동과 영양소 섭취 및 질적 상태에 관한 연구

        이영순,정귀영,김성미,Lee Young-Soon,Jung Kwey-Young,Kim Sung-Mee 동아시아식생활학회 2006 동아시아식생활학회지 Vol.16 No.1

        This is an analysis of the dietary behavior, nutrient intake status and INQ(Index of nutritional quality) of 129 college women according to their residences in the Daegu area. The average height and weight were 160.0 cm and 54.5 kg respectively. Diet intake data were obtained by using the 24-hour recall method to evaluate the usual diet of the subjects. The energy intake of the group, living alone was higher than that of living a roommate and living at home. Ca, Fe, Zn and folate intakes were low in all the groups. The composition rate of carbohydrate, protein and fat for energy intake was 58.9 : 15.5 : 25.6 in living alone, 59.9 : 15.1 : 25.0 in living with a roommate and 61.2 : 15.5 : 23.3 in living at home, compared with the preferred of 65 : 15 : 20. The group living alone showed significantly better mean adequacy ratio(MAR, 0.7) than the other groups (p<0.05). The group living with a roommate showed significantly better INQ in vitamin $B_6$ (p<0.01) and Fe (p<0.05) than the other groups did In conclusion, this study indicates that nutrient intake in college women in Daegu is considerably lower than the RDA values. Furthermore the group living alone showed better dietary behavior and nutrient intake status than the other groups. A nutrition education program for college women is necessary.

      • KCI등재

        영남지역 초등학생과 고등학생의 식습관 및 음식기호도에 관한 연구

        윤영옥,이영순,김성미,Yoon Young-Ok,Lee Young-Soon,Kim Sung-Mee 동아시아식생활학회 2006 동아시아식생활학회지 Vol.16 No.1

        To analyze the dietary behavior and food preference of Korean youth, we surveyed 140 elementary school 6th grade students and 154 high school first grade students in Youngnam Provinces. The average height and weight for the elementary school students were 153cm and 45.3kg for boys and 153.4cm and 44.6kg for girls. The body types depending on the body mass index(BMI) were 45.7% for under-weight, 47.1% for standard, 3.6% for overweight and 3.6% for obesity. The average height and weight for the high school students were 172.5cm and 64.5kg for boys and 160.1cm and 51.7kg for girls. The body types depending on the BMI were 11.0% for under-weight, 70.8% for standard, 13.0% for overweight and 5.2% for obesity. In their food preference, they preferred one-dish food to main dishes and rice with cereals was more popular among high school students. There were higher standard scores in fruit, snack, fried, and Kimchi dishes and high school students showed a high preference especially for snack and fried foods. The Kimchi dishes were more popular among elementary school students and they showed high scores in those dishes regardless of how they were cooked. There was the lowest preference for Korean vegetable salad and the highest for food cooked with meat In conclusion, a difference was found in the food preference of elementary school and high school students and the nutrient intake of elementary school students was lower than that of high school students. Therefore, elementary schools should provide proper nutritional education for students.

      • KCI등재

        2002년 부산 지역에서 유행한 무균성 뇌막염에 대한 임상적 고찰

        박지현,이나영,김길현,정진화,조경순,김성미,Park, Ji Hyun,Lee, Na Young,Kim, Gil Hyun,Jung, Jin Hwa,Cho, Kyung Soon,Kim, Sung Mi 대한소아청소년과학회 2003 Clinical and Experimental Pediatrics (CEP) Vol.46 No.9

        목 적 : 2002년 부산 지역에서 집중 발생한 무균성 뇌막염의 임상 양상 및 원인 바이러스를 알아보고자 본 연구를 시행하였다. 방 법 : 2002년 1월부터 12월까지 부산 메리놀병원에 무균성 뇌막염으로 입원하였던 276명의 환아를 대상으로 임상 소견을 조사하였고, 이 중 244명은 뇌척수액, 대변, 인후 도말 검체로 바이러스 배양 검사를 실시하였다. 결 과 1) 성별 분포는 남아 160례, 여아 116례로 남녀비는 1.4 : 1이었다. 2) 연령별 분포는 5개월에서 14세까지였으며, 평균 연령은 $5.7{\pm}6.2$세였고, 1-4세에서 114례(41.3%)로 호발하였다. 3) 환자의 발생 시기는 5-7월에 집중 발생하였다. 4) 임상 증상은 발열, 두통, 구토 순으로 나타났고, 6-7월에는 호흡기계 감염 증상이 동반되었으며, 11-12월에는 10세 이상의 소아에서 발열 없이 두통 및 오심이 특징적으로 나타났다. 5) 말초 혈액 소견상 $10,000/mm^3$ 이상이 34.8%, ESR 20 mm/hr 이상이 56.1%, CRP 양성이 61.0%로 말초 혈액 검사로는 세균성 감염과 감별 진단이 어려웠다. 6) 뇌척수액 검사상 백혈구수는 $86.5{\pm}180.2/mm^3$, 단백질은 평균 $41.7{\pm}32.9mg/dL$, 당은 평균 $56.4{\pm}9.9mg/dL$이었다. 7) 재원 기간은 평균 $4.7{\pm}7.2$일이었고, 이 중 요추 천자를 시행한 군이 시행하지 않은 군에 비해 재원 기간이 훨씬 짧고 증상 소실도 빨랐으며, 항생제 사용 기간도 짧았다. 8) 뇌척수액 바이러스 배양 검사상 echovirus 6이 14례, echovirus 9가 8례, coxsakie virus B3가 4례, echovirus 25가 1례, coxsakie virus B4가 1례, untypable virus가 4례에서 검출 되었다. 결 론 : 2002년도에 부산 지역에서 무균성 뇌막염의 대유행이 있었으며, 원인 바이러스는 echovirus 6, 9, 25, coxsakie virus B3, B4이었다. Purpose : There was a outbreak of aseptic meningitis in Busan, 2002. We report the clinical features and causative viruses. Methods : Two hundred seventy six children with aseptic meningitis who were admitted to the Department of Pediatrics, Maryknoll Hospital between January and December, 2002 were included. CSF, stool and throat swab viral cultures were done in 244 of these children. Results : The male to female ratio was 1.4 : 1. Age of patients varied from five months to fourteen years old. Average age was $5.7{\pm}6.2years$ old and mostly between one and four years.(41.3%) Monthly distribution revealed that the number of patients increased from May to July. The main symptoms were fever, headache and vomiting in this order. Respiratory tract infection symptom was associated from June to July and headache and nausea without fever were characteristically observed in children more than 10 years old from November to December. In peripheral blood examination, leukocytosis(WBC>$10,000/mm^3$) showed in 34.8%, ESR was increased in 56.1%, and CRP was positive value in 61%. Therefore differential diagnosis was difficult through peripheral blood examination. CSF findings revealed mean leukocyte count $86.5{\pm}180.2/mm^3$, protein $41.7{\pm}32.9mg/dL$, glucose $56.4{\pm}9.9mg/dL$. Median hospitalized period was $4.7{\pm}7.2days$ and compared with non-tapping group, hospitalized period was shorter and subsidance of symptoms was faster, therefore antibiotics injection period was shorter in the spinal tapping group. Virus was isolated in 31 cases of 244. The causative agents were echovirus 6, echovirus 9, echovirus 25, coxsakie virus B3, B4. Conclusion : There was an epidemics of aseptic meningitis in Busan, 2002; the causative agent was echovirus 6, 9, 25, coxsakie virus B3, B4.

      • 소아 급성 하기도 감염의 바이러스 원인 및 임상 양상 (2002년 부산 지역)

        이나영,박지현,김길현,정진화,조경순,김성미,Lee, Na Young,Park, Ji Hyun,Kim, Gil Hyun,Jung, Jin Hwa,Cho, Kyung Soon,Kim, Sung Mi 대한소아감염학회 2003 Pediatric Infection and Vaccine Vol.10 No.1

        목 적 : 호흡기 바이러스는 인간에게 가장 전염성이 강한 병원체의 하나로 급성 호흡기 감염 특히 하기도 감염증은 소아에서의 유병률과 사망률의 주요 원인이 되고 있다. 저자들은 하기도 감염증에 이환된 환아들을 대상으로 influenza A, B virus, adenovirus, enterovirus의 감염 연령 분포와 계절적 유행 양상, 바이러스별 임상 양상을 알기 위하여 이 연구를 시작하였다. 방 법 : 2002년 1월부터 2002년 12월까지 부산 메리놀병원에 입원하거나 외래 방문한 하기도 감염증 소아들을 대상으로 인후 가검물, 콧물, 타액 분비물 등을 채취하여 바이러스를 동정하였고, 검사를 시행한 568명 중 바이러스가 동정된 54명을 대상으로 호발 연령, 유행 시기, 임상 증상을 후향적으로 조사하였다. 결 과 : 1) 대상 환아의 연령 분포는 2개월부터 14세 사이였고, 남녀비는 1.8 : 1이었다. 3~6세가 29.6%로 가장 많았고, 2~3세 사이가 14.8%, 12세 이상이 13% 순이었다. 2) 동정된 바이러스는 influenza A virus가 59.3%로 가장 많았고, enterovirus가 33.3%, adenovirus 5.6%, influenza B virus 1.9%였고, parainfluenza virus와 RSV는 동정되지 않았다. 3) 임상 양상은 폐렴이 51.9%로 가장 많았고, 기관지염이 31.5%, 크루프 9.3%, 모세기관지염 7.4%의 순이었다. 4) 호흡기 바이러스는 각각의 유행 시기가 있어, influenza A virus는 3~5월, 11월에 2차례의 유행이 있어 주로 겨울에 유행하는 양상을 보였으며, influenza B virus는 3월에, adenovirus는 3월과 7월에, enterovirus는 3~7월에 유행하여 주로 봄부터 여름까지 유행하는 양상을 보였다. 결 론 : 2002년 부산 지역 호흡기 바이러스 감염의 주된 원인은 influenza virus였다. 이러한 결과는 influenza virus의 유행을 보여주는 것으로 이에 대한 지속적인 감시와 예방, 조기 진단과 치료가 필요하다고 하겠다. Purpose : Respiratory viruses are one of the most infectious agent in human. Acute lower respiratory tract infection(ALRTIs) is associated with significant morbidity and mortality in children. This study is performed to investigate the etiologic organism, age and sex distribution, clinical manifestations and seasonal occurrence of ALRTIs in children. Methods : Viral agent was evaluated with nasopharyngeal aspirates, rhinorrhea and saliva collected from 568 patients. We confirmed viral agents in 54 patients who were younger than 15 year old. They had visited Maryknoll Hospital, Busan in Korea from January, 2002 to December, 2002 for ALRTIs. Results : The viral pathogens identified were Influenza A virus(59.3%), Enterovirus(33.3%), Adenovirus(5.6%), and Influenza B virus(1.9%). Parainfluenza virus and Respiratory syncytial virus were not detected. The occurrence of acute lower respiratory infections was high between 3 & 6 years old. The clinical patterns include pneumonia(51.9%), bronchitis(31.5%), croup(9.3%), bronchiolitis(7.4%). The respiratory viral agents had their characteristic seasonal patterns. Conclusion : Influenza A virus was the most common cause of acute lower respiratory tract infections in Busan area during the 2002. ALRTIs had high occurrence between 3 to 6 years old. And the most common clinical patterns were pneumonia and bronchitis.

      • KCI등재후보

        영남지역 기혼여성의 사회·경제적 수준이 외식행동에 미치는 영향

        김성미,이영순 동아시아식생활학회 2004 동아시아식생활학회지 Vol.14 No.2

        The purpose of this study was to investigate the effects of socioeconomic status on the eating-out satisfaction, eating-out expenditure, meal balance and dietary attitude of 251 married females in Youngnam Area. The monthly frequency of eating out with family was 2.5 visits with an expenditure of 116,000 won in this study. Korean food was the most frequently selected type of board for breakfast, lunch and dinner. The respondents satisfied with the taste of the food the most, whereas least satisfied with the sanitation. The average expenditure for eating-out was 62,000 won per visit with the average of 39,000 won in the lowest income group and 78,000 won in the highest one. Regarding the meal balance score, the overall score was 3.48 with the lowest score(2.98) being recorded for the dairy products and the highest score(3.95) for vegetables. As for the dietary attitude score, breakfast scored the highest(3.79) and consideration of balanced workload, exercise, rest and dining activities received the lowest score(2.57). Meal balance and attitude scores were not significantly different among the eating-out expenditure levels. The eating-out expenditure demonstrated a positive correlation with total food expenditures, household income, educational attainment and others. The low income group who had low meal balance scores and dietary attitude scores tended to spend proportionally more on eating-out. In conclusion, the studies revealed that the respondents favored the Korean food and did not satisfied with the sanitation most when eating-out. In terms of eating-out expenses, the group with the highest income and educational attainment spent the most on eating-out and food expenditures.

      • KCI등재

        대구 일부 지역 중학생의 식행동·체질량지수와 영양소 섭취상태에 관한 연구

        정귀영,이영순,김성미 동아시아식생활학회 2005 동아시아식생활학회지 Vol.15 No.1

        Dietary behavior, body mass index(BMI) and nutrient intake status of 185 boys and 205 girls in 3rd grade middle school students in Daegu area were analyzed. Boys were 168.6㎝ tall and weighed 61.3㎏ on the average and girls 158.5㎝ and 54.4㎏, respectively. From their BMIs, 17.9% were classified as the underweight, 54.2% as the average, 14.7% as the overweight and 13.2% as the obesity. The average energy intake per day was 2222.6 ㎉ for boys, 1796.2 ㎉ for girls which were 83.3% and 86.6% of the RDA, respectively. Composition rate of carbohydrate, protein, fat in relation to energy intake was 62.4 : 16.5 : 21.1 for boys and 58.8 : 16.0 : 25.2 for girls. Protein was taken low and carbohydrate and fat were high in this study. Particularly, fat intake rate of girls was high. Calcium, iron, vitamin A, and vitamin B2 did not meet the RDA and especially calcium was taken 63.9% for boys and 54.01% for girls. Most of the students have tendency to eat irregularly and to overeat. For the nutrients intake, calories and calcium intake were lower than the RDA regardless of gender and iron intake was not enough for girls only. In relation to BMI, obesity group students were taking lower calories and proteins than the normal students were. No consistent trend was shown for boys about nutrient intake in relation to eating speed. Students had a correct perception of their body image which was similar to that of their mothers. Nutrient average intake is under the average and the percentile under 70% of RDA was high contrary to the fact that nutrient intake like calcium and iron was exceedingly important particularly in the growth process. Therefore, nutritional education for the proper intake of nutrients was required for the students in Daegu area. Especially, education has to be focused on the balanced diet and correct food choices for the proper dietary behaviors.

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