악성 흉수, 결핵성 흉수 및 부폐렴 삼출액과 농흉에서 Interferon-gamma, Interleukin-2 Receptor, Interleukin-6, Interleukin-10 농도의 비교

김명훈,김승준,박용근,김석찬,이숙영,김영균,김관형,문화식,송정섭,박성학,Kim, Myung-Hoon,Kim, Seung-Joon,Park, Yong-Keun,Kim, Seok-Chan,Lee, Sook-Young,Kim, Young-Kyoon,Kim, Kwan-Hyoung,Moon, Hwa-Sik,Song, Jeong-Sup,Park, Sung-Hak 대한결핵및호흡기학회 2000 Tuberculosis and Respiratory Diseases Vol.49 No.5

연구배경 : Cytokine은 주요한 염증 매개 물질로서 질환에 따라 다른 양상을 보일 수 있어, 흉수를 일으키는 다양한 원인 질환의 감별에 이용되어 왔다. 이 중에서 악성 흉수, 결핵성 흉수, 부폐렴 삼출액 및 농흉에서 INF-${\gamma}$, IL-2R, IL-6, IL-1를 동사에 측정하여 비교한 연구는 많지 않아 본 연구를 시행하게 되었다. 방법 : 흉수를 주소로 내원한 환자 중에서 흉수 천자로 삼출액이 확인된 환자들을 대상으로 흉수를 채취하여, ELISA kit를 이용하여 INF-${\gamma}$, IL-2R, IL-6, IL-10 농도를 측정하였다. 결과 : 악성 흉수, 결핵성 흉수, 부폐렴 삼출액 및 농흉에서 흉수 내의 cytokine의 순서대로, INF-${\gamma}$는 $16.7{\pm}50$, $295.5{\pm}585.5$, $10.0{\pm}0$ pg/ml, IL-2R은 $3247.4{\pm}1713.3$, $7423.5{\pm}3752.8$, $3790.2{\pm}3201.1$ pg/ml, IL-6는 $600{\pm}12.8$, $556.4{\pm}161.7$, $514.4{\pm}224.8$ pg/ml, IL-10은 $28.2{\pm}55.5$, $11.3{\pm}11.7$, $98.4{\pm}141.7$ pg/ml로 각각 측정되어, 결핵성 흉수가 다른 원인의 흉수에 비해 IL-2R 농도가 의 있게 높았으며, IFN-${\gamma}$ 농도도 높은 경향을 나타내었으며, 부폐렴 삼출액에서는 IL-10농도가 다른 원인의 흉수에 비해 의미있게 높았다. 결론 : 결론적으로 흉수 내의 IL-2R농도 측정은 결핵성 흉수와 다른 원인의 흉수를 감별하는데 어느 정도 도움이 될 것으로 사료되며, IL-10 측정은 부폐렴 삼출액과 다른 원인의 흉수를 감별하는데 어느 정도 도움을 줄 것으로 생각된다. Background : Cytokines are chemical mediators that control and modulate many inflammatory processes. They work in different fashions in a variety of diseases. Discriminating between malignant effusion, tuberculous effusion, and parapneumonic effusion are crucial from the clinical view-point in Korea. In the current study, interferon-gamma (IFN-${\gamma}$), soluble interleukin-2 receptor (IL-2R), interleukin-6 (IL-6) and interleukin-10 (IL-10) were measured for this purpose. Methods : Pleural fluids from patients with malignant disease, tuberculosis, parapneumonic effusion and lung empysema were collected and gauged using commercial ELISA kits. Results : 34 patients were enrolled in this study. Among these 15 cases were malignant effusions, 12 were tuberculosis pleurisy and 7 were parapneumonic effusion and lung empyema. The levels of cytokines measured in this study were as follows, in order of frequency, malignant effusion, tuberculous effusion, parapneumonic effusion and lung empyema. The levels of INF-${\gamma}$ were higher in tuberculous effusion than in malignant or parapneumonic effusion ($295.5{\pm}585.5$ vs. $16.7{\pm}50$ vs. $10.0{\pm}0$ pg/ml, p>0.05). The levels of IL-2R were higher in tuberculous effusion than in malignant or parapneumoruc effusion ($7423.5{\pm}3752.8$ vs. $3247.4{\pm}1713.3$ vs. $3790.2{\pm}3201.1$ pg/ml, p<0.05). No significant differences were found in the levels of IL-6 between the groups ($600{\pm}12.8$ pg/ml in malignant effusion, $556.4{\pm}161.7$ pg/ml in tuberculous effusion, $514.4{\pm}224.8$ pg/ml in parapneumoruc effusion). IL-10 levels were higher in parapneumoruc effusion than in malignant or tuberculous effusions ($98.4{\pm}141.7$ vs. $28.2{\pm}55.5$ vs. $11.3{\pm}11.7$ pg/ml, p<0.05). Conclusion : These results suggest that the measurement of IL-2R levels in pleural fluids may be a useful means of differentiating between tuberculous effusion and pleural effusions of other origins, and that the measurement of IL-10 levels in pleural fluids may be useful to differentiate between parapneumonic effusion and pleural effusions of other origins.

정상근과 근막 유발점이 활성화된 근육의 초음파 영상의 비교

김명훈,김수현,김현진,Kim, Myung-Hoon,Kim, Su-Hyon,Kim, Hyun-Jin 대한물리치료학회 2013 대한물리치료학회지 Vol.25 No.2

Purpose: The objective of this study was to offer primary clinical data examining whether change of imaging structure and quantitative evaluation of muscle activity on myofascial trigger points can lead to implementation of an analytical technique for evaluation of myofascial pain diagnoses. In addition, we examined the effect of a variety of mediation techniques, in order to examine neuromuscular physiological characteristics of myofascial trigger points muscle by comparing differences in pressure pain threshold and ultrasound imaging. Methods: Participants in the study included 30 adults in their twenties. The subjects were divided into the normal and myofascial trigger points groups. Clinical outcomes were evaluated by pressure pain threshold for pain and ultrasound imaging was performed for evaluation of the structural characteristics of muscle. Independent t-test was used for statistical analysis. Results: The two groups showed statistical significance in the change in pressure pain threshold (p<0.05). Findings of ultrasound imaging analysis showed no significant differences, increased muscle thickness was observed (p>0.05). Findings of ultrasound imaging analysis showed significant differences, increased muscle echodensity was observed (p<0.05). Findings on ultrasound imaging analysis showed significant differences, increased muscle white area index was observed (p<0.05). Conclusion: From these results, active myofascial trigger points muscle showed quality deterioration on ultrasound imaging. Thorough evaluation of imaging structure and physiological characteristics can be useful quantitative analytical techniques for diagnosis of myofascial pain syndrome and a primary factor reflected in physical therapy intervention.

전자기록 환경에서의 '업무친화적' 기록관리 방향성 분석

김명훈,Kim, Myoung-Hun 한국과학기술정보연구원 과학기술정보센터 2007 Journal of Information Science Theory and Practice Vol.38 No.4

본고에서는 전자기록 환경에서의 기록관리 패러다임 변화에 대한 한 단면으로서, '업무친화적' 기록 관리의 향방에 대해 논의하고자 한다. 우선 전자기록 환경의 특성을 기반으로 업무와 기록, 기록관리의 상관관계를 심층적으로 분석한 다음, 전자기록 환경에서 기록관리가 지니게 되는 의미 및 역할의 방향성을 제시코자 한다. 이를 통해 본고에서는 종래의 라이프사이클 체제하에서 간과되어 왔던 현용기록관리의 의의 및 역할을 전자기록 환경에서 재정립함과 더불어, 나아가 기록관리와 정보관리의 연계를 위한 이론적 기반을 제공할 것이다. This article analyzes the direction of 'business-Friendly' record management in electronic records environment which means paradigm shift in record management. In the first place, this article investigates the interrelationship of business, records and record management through natures of electronic records, and analyzes direction of purposes and roles of record management in electronic records environment. After all, this article rebuilds a significance and roles of record management in active stage, and provides theoretical bases for close relation between record management and information management in electronic records environment.

물리치료사의 직무만족과 이직의도에 관한 연구

김명훈,Kim, Myung-Hoon 대한물리치료과학회 2001 대한물리치료과학회지 Vol.8 No.1

This study was attempted to examine the relationship between job satisfaction and turnover intention of physical therapist in order to suggest some method to enhance their job performance and the degrees of job satisfaction. High turnover intention of physical therapist is one of the serious problems at the present time which providing low quality physical therapy. The data were collected from July 1, to August 31, 2000 and analyzed by ANOVA, Pearson Correlation Coefficients. The summarized result are as follows: 1. The job satisfaction score of physical therapists showed the highest of the pride of patient treatment and total mean score was 2.96. 2. Those who were in the range of 26 to 30 years of age showed the strongest desire to leave the hospital 3. There were 68.8% in male. 47.6% in female who hoped to turnover intention. 4. There were significant difference between those who want to leave and those who want remain in relation patient number, work hospital work years. 5. There were no significant difference between those who want to turnover intention and those who want remain in relation patient number and work years. 6. The major reason for job satisfaction were work time and work areas.

영국의 의료체계

김명훈,Kim, Myeong-Hun 대한병원협회 1993 대한병원협회지 Vol.22 No.1.2

키네시오 테이핑과 발목관절 근력 운동이 균형지수에 미치는 변화

김명훈,이정훈,김찬규,Kim, Myung-Hoon,Lee, Jeong-Hun,Kim, Chan-Kyu 대한물리치료학회 2009 대한물리치료학회지 Vol.21 No.3

Purpose: This study examined that effect of a change in balance index on ankle Kinesio taping, muscle strength exercises and taping after muscle strength exercises in 30 healthy adult subjects. Methods: The Sway Index of the left, right, front and back on stable, toes up and linear were compared using a Balance System, a balance experimental instrument. Results: The pre and post experimental balance index regarding stable, toes up, and linear were taken for the Kinesio taping group, lower extremities muscle strengthening group, and muscle strengthening with the Kinesio taping group. Statistically significant decreases were observed in all variables except for the left and right pre and post experiment results under stable conditions. Conclusion: The balance index of exercise with taping was lower than that of exercise only. There is a need for objective research on the long-term applications and post-exercise. The body balance appears to be influenced by ankle stabilization using taping.

레코드 컨티뉴엄과 평가, 그리고 기록콘텐츠 -기록콘텐츠 개념 정립을 위한 시론-

김명훈,Kim, Myoung-Hun 한국과학기술정보연구원 과학기술정보센터 2010 Journal of Information Science Theory and Practice Vol.41 No.3

본고에서는 레코드 컨티뉴엄 이론 속에 내재된 평가 논리를 기반으로, 전자기록 환경 속에서 기록이 지닌 의미 및 기록관리의 역할을 모색해 보고자 한다. 레코드 컨티뉴엄 이론에서 의도하는 평가 논리는 최근의 다원화 된 사회에서 기록의 의미 및 기록관리의 역할을 모색하는 데 유용한 이론적 기반을 제시해 줄 수 있다. 아울러 레코드 컨티뉴엄의 평가 논리를 통해 모색된 증거성을 지닌 가치 있는 기록의 의미 및 활용성 확대를 위한 방안으로 '기록콘텐츠'의 개념화를 시도하였다. This article intends to explore the meaning of record and role of record management in electronic record environments, based on appraisal theory of Records Continuum. Appraisal theory of Records Continuum can provide to explore the mean of record and role of record management in new social environment. And it try to build the Concept of archival contents for expanding the meaning and utilization of record based on appraisal theory of Records Continuum.

사진 디지털아카이브 구축에 관한 연구 : 민주화운동 사진기록을 중심으로

김명훈,현종철,Kim, Myoung-Hun,Hyun, Jong-Chul 한국과학기술정보연구원 과학기술정보센터 2006 Journal of Information Science Theory and Practice Vol.37 No.3

본 연구에서는 민주화운동 관련 사진들을 기반으로 한 사진 디지털아카이브 구축 프로세스를 분석하였다. 사진 디지털아카이브를 디지털 객체를 대상으로 수집, 분류, 기술, 저장, 활용시키는 통합적 시스템으로 규정한 후, 사진의 고유성을 반영한 메타데이터의 도출 및 분류체계 수립 사례를 제시하였다. 특히 사진 디지털아카이브의 분류체계 수립 시, 기존의 기본분류체계 외에 다양한 검색어를 활용한 다원분류체계를 설계함으로써, 문자화된 의미전달이 부재한 사진들 간의 통합성 및 상호연계성을 창출시켜 활용성을 극대화시킬 수 있는 방안을 제시하고자 하였다. This article analyze a constructing process of photographic digital archive based on photographs of korean democratization movements. After photographic digital archive defines as integrated systems in which photographic digital objects collect, classify, describe, preserve and access, this article explains metadata elements and classification schema reflecting a special quality of photograph. Especially, this article presents dynamic classification structure using subject keywords. After all, this method provides integrity and interrelationship with photographes which promote usability of photographic digital objects.

전자기록 환경에서의 기능평가 프로세스 분석

김명훈,Kim, Myoung-Hun 한국과학기술정보연구원 과학기술정보센터 2008 Journal of Information Science Theory and Practice Vol.39 No.4

본고에서는 기록물의 내용이 아닌 기록이 생성된 기능에 기반을 두고 행해지는 전자기록 환경에서의 기능평가 프로세스를 분석하였다. 전자기록 환경에서 기능평가는 가장 보편화된 평가방식으로, 기록물의 생산 이전단계부터 수행되는 연속적인 업무 프로세스를 형성하게 된다. 종국적으로 기능평가를 기반으로 하는 전자기록 환경에서의 평가는 업무맥락 및 기록품질을 지님과 동시에, 조직의 영위 및 업무 수행에 필수적인 전자기록을 선별해 주게 된다. This article minutely examines functional appraisal process that focuses on not content but function in which the records are created. Taking everything into consideration, functional appraisal in electronic record environments constitutes consecutive process that is performed organically in pre-creation stage of records. Ultimately functional appraisal in electronic record environments is organic process selecting electronic records across phases of whole record management, which assure business context and recordness, and need to run organization and perform business.

정상안압녹내장, 고안압녹내장 및 정상 대조군 사이의 식생활 습관 비교

김명훈,박성철,이선희,기창원,Myung Hun Kim,Sung Chul Park,Seonheui Lee,Changwon Kee 대한안과학회 2011 대한안과학회지 Vol.52 No.2

Purpose: To compare the dietary patterns between normal or high tension glaucoma patients and a normal control population. Methods: A survey using the self-assessment food-frequency questionnaire was given to normal tension glaucoma (NTG) or high tension glaucoma (HTG) patients who visited a glaucoma clinic between June 2008 and September 2008. Healthy Korean subjects who had received routine health examinations at Samsung Medical Center between October 2007 and September 2008 were evaluated with the same questionnaire. Statistical analysis of variable factors including fatty fish, seaweeds, soy products and greasy meats, was performed to compare between groups. Results: Sixty-two of NTG patients, 25 of HTG patients and 29,376 normal subjects were included in the present study. The mean age of each group was 51.3 ± 13.4, 51.8 ± 17.4 and 50.5 ± 10.4 years, respectively. No significant difference in dietary pattern was found between the subjects with glaucoma and the normal controls (p > 0.2 in all factors). The dietary pattern of NTG and HTG patients showed no statistically significant difference in all factors (p > 0.2). Conclusions: There was no significant difference in a dietary pattern between glaucoma patients and normal subjects. In terms of glaucoma, no possible beneficial or harmful food was found. J Korean Ophthalmol Soc 2011;52(2):216-221