CG실험에 의한 실내마감재의 평가 예측 모델 작성

이진숙,진은미,박유미 대한건축학회 2003 대한건축학회논문집 Vol.19 No.2

The purpose of this study is to evaluate the features of the finishing material according to their type and color. The purpose of this in order is to improve the pleasantness of the interior, by using the proper finishing materials, in planning the interior, and to apply it to framing the prediction model for practical use in interior design, This stud was conducted by evaluating experiment manufactured with the CG(Computer Graphics). The process of the study is as follows, 1) The finishing materials used in the interior based on the previous study was classified. The color range of the selected finishing materials was examined. 2) The evaluation experiment using the CG was conducted on the basis of the selected finishing materials. 3) With that result, the evaluation properties was analyzed according to evaluating variables(that is, the finishing material, hue, value, and chroma) for the interior image. 4) Finally, the prediction model of the interior finishing materials was framed with the image type. Through the Factor Analysis of 19 Adjectives, 8 representative image types such as 「Open·Bright」, 「Gorgeous·Strong」, 「Quiet·Natural」, 「Smooth·Elaborate」, 「Coarse·Rough」, 「Elegant·Refined, 「Warm」」 and 「Cool」 were extracted. The prediction model was framed for the 8 representative image types. The 「Open·Bright」, 「Quiet·Natural」, 「Cool」images are as follows, 1) When you want to produce the 「Open·Bright」image, it is ideal to use wallpaper as finishing material and Y or B in hues. The higher the value and middle chroma you use. The bigger 「Open·Bright」 the efficiency you achieve. 2) When you want to produce the 「Quiet·Natural」 image, it is good to use woods for finishing materials, You can get a better image with the YR or R in hues, with higher value and lower chroma. 3) When you want to produce the 「Cool」image, it is better to use stones for finishing materials. Cool colors and the hue of B, PB, BG are recommended. The lower value and chroma are effective as well.

한국형 가정보육시설의 디자인지침 개발을 위한 이론적 고찰

이유미(You-Mi Lee),김미희(Mi-Hee Kim) 전남대학교 생활과학연구소 2005 生活科學硏究 Vol.15 No.-

Family day care centers in apartment complexes, which are popular in Korea, have merits as day care centers for young children due to their homey environments, closeness to children’s homes, and available outdoor playgrounds utilizing open space in the complexes. Thus, there is a great potential to develop a design guideline for family day care in apartments which are in demand now. The purpose of this study is to provide basic information for developing a design guideline for family day care centers. Therefore, this study aimed to investigate the important issues that influence the development of design family day care center. These issues are environment behavior. Murtha & Lee’s User Benefit Criteria, and Pattern theory. As a result, this study provides basic data for developing a design guideline for family day care and as a base for the next study.

Function of the pentose phosphate pathway and its key enzyme, transketolase, in the regulation of the meiotic cell cycle in oocytes

Kim, Yunna,Kim, Eun-Young,Seo, You-Mi,Yoon, Tae Ki,Lee, Woo-Sik,Lee, Kyung-Ah The Korean Society for Reproductive Medicine 2012 Clinical and Experimental Reproductive Medicine Vol.39 No.2

Objective: Previously, we identified that transketolase (Tkt), an important enzyme in the pentose phosphate pathway, is highly expressed at 2 hours of spontaneous maturation in oocytes. Therefore, this study was performed to determine the function of Tkt in meiotic cell cycle regulation, especially at the point of germinal vesicle breakdown (GVBD). Methods: We evaluated the loss-of-function of Tkt by microinjecting Tkt double-stranded RNAs (dsRNAs) into germinal vesicle-stage oocytes, and the oocytes were cultured in vitro to evaluate phenotypic changes during oocyte maturation. In addition to maturation rates, meiotic spindle and chromosome rearrangements, and changes in expression of other enzymes in the pentose phosphate pathway were determined after Tkt RNA interference (RNAi). Results: Despite the complete and specific knockdown of Tkt expression, GVBD occurred and meiosis was arrested at the metaphase I (MI) stage. The arrested oocytes exhibited spindle loss, chromosomal aggregation, and declined maturation promoting factor and mitogen-activated protein kinase activities. The modified expression of two enzymes in the pentose phosphate pathway, Prps1 and Rbks, after Tkt RNAi and decreased maturation rates were amended when ribose-5-phosphate was supplemented in the culture medium, suggesting that the Tkt and pentose phosphate pathway are important for the maturation process. Conclusion: We concluded that Tkt and its associated pentose phosphate pathway play an important role in the MI-MII transition of the oocytes' meiotic cell cycle, but not in the process of GVBD.

공동주택단지 옥외공간계획 수준 평가를 위한 정성적 평가지표 선정에 관한 연구

이유미,김성우 대한건축학회 2003 대한건축학회논문집 Vol.19 No.1

This study aims to select qualitative indicators as a means to evaluate the quality of outdoor spaces design in multi-family housing. According to the analysis of correctness and usefulness of qualitative indicators in outdoor spaces, the qualitative indicators are selected. The correctness and usefulness of qualitative indicators are examined by 2 words. One is analyzing the results of experts' questionnaire survey about the criteria of preference of 16 multi-family housing. As a result 6 environmental qualitative indicators are proposed and 18 environmental qualitative detail indicators are proposed. 6 environmental qualitative indicators are: Recreational Space Planning, Green Space Planning, Pedestrian Space Planning, Traffic Road and Parking Space Planning. Building Blocks Planning and Landscaping.

소목(Caesalpinia sappan) 추출물의 Streptococcus mutans에 대한 성장, 산생성, 부착 및 비수용성 글루칸 합성 억제에 미치는 영향

유용욱,유현희,김윤정,유미선,서세정,이황,이흥수 대한구강보건학회 2003 大韓口腔保健學會誌 Vol.27 No.2

Streptococcus mutans is known as the causative bacterial playing the most important role in forming plaque and it is being noticed as major causative bacteria of dental caries. Therefore, development of more effective, substantial and safe preventive agent against dental caries and periodontal disease is honestly required. The present study was designed to investigate the effect of chloroform extract(CE), n-butanol extract(BE),methanol extract(ME) and water extract(WE) of Caesalpinia on the growth, acid production, adhesion, and insoluble glucan synthesis of Streptococcus mutans. The CE, BE, ME and WE decreased the growth and acid production of S.mutans than that of control, especially, the ME was more effective than other extracts. The effect of CE, BE, ME and WE on the adherences to saliva-coated hydroxyapatite bead(S-HA) were evaluated. At the concentration of 2,000 ㎍/㎖, the CE showed 32% rate of bacterial adherence to S-HA, whereas, other extracts of the same concentration producedgreater than 50% rate. The CE and BE were significantly decreased the reduction rates of water insoluble glucan formation from sucrose by crude glucosyltransferase of S.mutans. Thus, the application of C. sappan can be considered a useful and a practical method for the prevention of dental caries.

공동주택단지의 옥외환경에 대한 정성적 평가지표와 거주자만족도사이의 상관성분석 연구

이유미,김성우 대한건축학회 2003 대한건축학회논문집 Vol.19 No.7

This study aims to investigate the usefulness of qualitative indicators proposed in Multi0Family Housing according to the analyzing works such as correlation analysis between the residents' satisfaction and the qualitative indicators etc. Therefore the 4 analyzing works are as follows : 1) analyzing the results of questionnaire survey on the experts about the evaluation of whole outdoor spaces of 15 multi-family housings. 2) analyzing the results of questionnaire survey on the residents about the evaluation of whole outdoor spaces of 15 multi-family housings. 3) analyzing the evaluation results of 15 multi-family housing by quantitative indicators 4)analyzing the results of researcher's evaluating of the site plans of 15 multi-family housings. As a result, 6 environmental qualitative basic indicators are proposed and 20 environmental qualitative detail indicators are proposed. 6 environmental qualitative basic indicators are Recreational Space Planning, Green Space Planning, Pedestrian Space Planning, Traffic Road and Parking Space Planning, Building Blocks Planning and Landscaping. The characteristics of environmental qualitative indicators proposed are as follows : 1) environmental qualitative basic indicators suggested are able to evaluate the area which are difficult to quantitative analysis according to above 6 plannings 2) environmental qualitative detail indicators suggested help evaluate objectively and concretely.

공동주택단지 옥외환경 평가를 위한 정성적 평가 지표의 활용가능성 분석에 관한 연구

이유미 상명대학교 자연과학연구소 2002 自然科學硏究 Vol.9 No.-

본 연구는 선행 연구에서 예비 선정된 정성적 평가지표의 활용가능성을 전문가의 옥외환경 질 평가 결과를 기반으로 하여 분석하였다. 정성적 평가를 위한 '기본 평가지표'의 활용가능성 분석을 위해 '전체 옥외환경의 질'과 정성적 평가를 위한 '기본 평가지표'간의 상관성 분석한 결과, 선행연구에서 제시된 6개의 '기본 평가지표' 모두 '전체 옥외환경의 질' 평가결과와 관계가 있는 활용가능성 높은 지표들임을 확인 할 수 있었다. 또 예비 선정한 정량적 평가 지표별 '세부 평가지표'의 활용가능성 분석을 위해 단지별 전문가 평가결과 분석, 도면에 의한 기본자료 분석, 예비 선정한 세부지표에 의한 각 단지 평가결과 분석을 실시하였다. 그 결과, 선행연구에서 예비 선정된 6개의 '기본 평가지표'와 18개의 '세부 평가지표'의 활용가능성을 확인하였으며 또 활용가능성이 높은 '휴식 및 놀이를 위한 옥외공간계획'과 관련된 새로운 '세부 평가지표' 2개를 추가 제안하였다.

청소년의 신체증상과 자아 존중감에 관한 연구

이미숙,최영,유지숙 대한신경정신의학회 2000 신경정신의학 Vol.39 No.2

연구목적: 본 연구는 Thomas의 청소년 증상목록(Adolescent Symptom Checkist : ASC)을 한국판으로 표준화하고 우리 청소년들이 호소하는 비특이적인 신체증상의 빈도, 성별, 학교 계열별, 학년별 차이, 자아존중감과 상관성을 알아보고 외국의 결과와 비교하고자 한다. 방법: 광주광역시 인문계, 실업계 남·녀 고등학생 794명이 참여하였으며 그들의 평균 연령은 17세 였다. 우리말로 번역된 Thomas 등의 청소년 증상목록(ASC), Rosenberg의 자존감 척도(Self-esteem Scale) 그리고 간이정신진단 검사 9개 척도 중 우울증 척도와 신체화 척도 문항이 사용되었다. 통계처리는 SPSS 8.0을 이용하여 내적 일치도 Cronbach a를 구하고 남녀군, 학교 계열별 비교는 t-test, 학년간의 비교는 ANOVA를 사용하였다. 결과: ASC의 내적일치도는 Cronbach a .89로 매우 높았다. 문항간 상관의 평균은 .29(.09∼.58)로 모든 문항간 상관은 계적으로 유의하였으며 문항 - 전체 상관의 평균은 .49(.23∼.63) 이었다. 또한 간이 정신진단 검사의 신체화와 우울 하위척도와는 정적 상관이 있었다. 전체 대상군의 약 17.8%가 고위험군이 었으며 외국의 11∼15% 보다 높았다. 69.4%는 지난 1년 동안 비특이적 신체증상을 주소로통 원을 찾은적이 있었고 26.2%는 최근 병원 치료를 받은 기왕력이 있었다. 남·녀의 신체증상은 p<.01 수준으로 여자에서 유의하게 높았으나 자아존중감의 남녀차이는 없었다. 인문계와 실업계간의 신체증상과 자아존 중감의 차이는 없었다. 그리고 학년간의 신체증상은 <.05 수준으로 학년이 올라감에 따라 증가하였으나 자아존중감은 차이가 없었다. 신체증상과 자아존중감의 상관은 p<.01 수준에서 부적 상관이 있었으며 이것은 남·녀, 인문계, 실업계, 각 학년 모두에서 일관되었다. 결론: ASC는 청소년의 신체증상을 평가하는 도구로서 신뢰도가 높아 임상에서의 유용성을 시사한다. 또한 청소년의 상당한 수가 의미있는 신체증상을 호소하며, 여학생이 남학생보다, 학년이 높을수록 신체증상 이 증가하며 신체증상을 많이 호소하는 청소년은 낮은 자아존중감을 갖는다는 것을 알았다. Objectives: The aims of this study were to develop the Korean version of Adolescent Symptom Checklist(ASC) which was devised by Thomas et al.(1988), to investigate descriptive data of somatic symptoms which our adolescents reported and to find the correlation between somatic symptom and self-esteem. And furthermore we compared our results with those of foreign countries. Method: The subject group was composed of 794 students who go to commercial or academic high school in kwangju city. they completed self rating questionnaires which include ASC, Self-esteem scale and somatization and depression subscales of SCL-90-R. The descriptive statistice, reliability and validity of ASC, means of somatic symptom and self-esteem for each group and correlation of somatic symptom and self-esteem were examined. We would consider an adolescent as belonging to high risk group if their score on the ASC was one or more standard deviations above the mean. Results: Seventeen point eight percent of all subjects were in high risk group and the pacentage was higher than 11-15% of foreign countries. Sixth nine point four percent had visited to hospital due to their somatic symptoms during the past 12months and 26.2% were treated by doctors recently. Internal consistency(Cronbach a .89) was high. Inter-item correlations were all positive and ranged from .09 to .58 with a mean of .29 and item-total correlations varied from .35 to .60 with a mean of .48. The ASC was significantly correlated with the somatization and depression subscales of SCL-90-R. Somatic symptoms of female group were much more frequent than those of male group. The higher their grade is, the more somatic symptoms they complained. There were signiticant negative correlations between somatic symptoms and self-esteem in all groups. Conclusions: By the result of this study, we suggest that ASC can be used as a tool for evaluation of adolescent's somatic symptoms. We showed that the frequency of somatic symptoms in adolescents were higher in females than in males, and were higher in upper grade than in lower grade. We also showed that the more somatic symptoms they complained, the lower self-esteem they had.

N-Arylnortropinone 유도체의 합성연구

李龍均,朴유미,鄭大一,金寅植,朴鍾勳,盧信愛,鄭逸守,朴敏洙 東亞大學校附設基礎科學硏究所 1998 基礎科學硏究論文集 Vol.15 No.1

Tropinone 화합물들은 색다른 고리계의 존재로 아주 오래전부터 약리학적으로 매우 흥미로운 연구과제로 주목되어 최근에 그들의 합성법,?? 입체적 구조분석?? 그리고 약리학적인 연구??가 활발히 진행되고 있다. Tropinone 1은 흔히 마약으로 알려져 있는 cocaine 2, 소염작용과 항경련성 작용 및 심장박동수를 조절 등 다양한 약리작용을 하는 tropane spirohy-dantoin ?? 그리고 안과질환을 검사 할 때 눈의 동공을 확장시키는 데 사용하는 atropine ??등을 합성하는 데 중요한 중간체이다. ??????????? Trigo, G, G등 ??은 aliphatic amine과 succinic aldehyde를 acetonedicarboxylic acid와 반응하여 nortropane 유도체를 합성하였으며, 그 후 [3+2] nitrone cycloaddition? 과 [3+4] cyclocoupling? 을 거치는 tropane alkaloid의 새로운 합성법이 개발되었다. 최근 lzquier M. L. 등¹은 acetonedicarboxylic acid를 사용하여 1차 지방족 amine과 succinic aldehyde대신 2,5-dimethoxytetrahydrofuran을 반응시켜 N-alkyl nortropinone 유도체를 합성하였다. 그러나 일반적으로 빙초산 속에서 amine과 2,5-dimethoxytetrahydrofuran을 반응시키면 pyrrole 유도체가 합성되어진다.?? 이러한 사실은 분명히 반응조건(예, 산, 온도)에 따른 다양한 화학이 존재한다고 볼 수 있다. 따라서 우리는 반응조건, 즉 산의 변화 및 온도 변화에 의한 amine과 2,5-dimethoxytetrahydrofuran의 반응을 자세하게 검토하면서 새로운 N-arylnortropinone 유도체를 합성하고자 한다.

광중합기를 이용한 광학적 치아우식활성도 검사법

이난영,김미라,오유향,이창섭,이상호 大韓小兒齒科學會 2004 大韓小兒齒科學會誌 Vol.31 No.4

레이저와 플라스마 광, 할로겐 광 중합기를 이용하여 각 개인의 우식 활성도를 측정할 수 있는지를 규명하기 위해 7-8세 아동 45명을 대상으로 치아의 순면과 협면에 각 광원을 조사하고 특수 필터를 사용하여 초기 치아우식증으로 판별된 치아의 개수를 측정하여 기존의 우식활성도 측정방법인 dDfFtT rate와 mutans streptococci 측정법 Lactobacilli 측정법과 비교, 평가하고 그 특이도, 민감도, 예측력을 평가하였다. 1. 아르곤 레이저, 플라스마 광, 할로겐 광 조사시 육안검사시 보다 유의하게 많은 초기우식 병소가 관찰되었다(p<0.05). 2. 아르곤 레이저, 플라스마 광, 할로겐 광을 이용한 우식활성도 측정법은 dDfFtT rate와 양의 상관관계(γ= 0.42, 0.41, 0.39)를 보였다(p<0.01). 3. 기존의 우식활성도 측정방법을 기준으로 하여 평가한 결과 특이도와 민감도, 예측력은 모두 레이저가 가장 높았으며 플라스마 광, 할로겐 광 순으로 나타났다. 이상의 결과를 종합하여 볼 때 아르곤 레이저와 플라스마 광, 할로겐 광을 이용한 형광법은 모두 양호한 진단학적 지표를 보여줌으로써 향후 광학적 우식활성검사법으로 활용 가능성이 높을 것으로 사료된다. The purpose of this study was to develop a practical caries activity test by fluorescence using laser, plasma light and halogen light. The subjects of study were 45 children of 7-8 years old. Argon laser, plasma light and halogen light were irradiated to buccal or labial surface of all teeth. Fluorescence of initial carious lesion from teeth was observed through barrier filter and the number of teeth showing lesion was counted. Visual examination for the dDfFtT, mutans streptococci screening test and Lactobacilli colony counting were also done. Data analysis was accomplished by Axelsson's method. The result from the present study can be summarized as follows. 1. Laser, plasma light and halogen light could detect the initial carious lesions better than visual examination(p<0.05). 2. There was positive correlation between laser(r=0.42), plasma light(r=0.41), halogen light(r=0.39) and dDfFtT rate(p<0.01). 3. The specificity, sensitivity and predictive value was showed highest value in laser. but was showed favorable value in plasma light and halogen light. In regard to above results, laser, plasma light and halogen light all considered to be reliable method for determining individual caries activity. And they were also considered to be practical method because it would be simple, inexpensive, and time saving method.