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        • KCI등재

          Molecular Characterization of Fusarium Graminearum Virus 2 Isolated from Fusarium graminearum Strain 98-8-60

          유지숙,김국형,이경미,손문일 한국식물병리학회 2011 Plant Pathology Journal Vol.27 No.3

          Fusarium graminearum virus 2 (FgV2) infects Fusarium graminearum strain 98-8-60 and has at least five segments of double-stranded RNAs (dsRNAs), denoted as dsRNA-1 to dsRNA-5. In this study, the genome of FgV2 was sequenced and its phylogenetic relationship with other mycoviruses was analyzed. The lengths of FgV2 dsRNAs 1–5 ranged from 2414 to 3580 base pairs (bp). The 5' and 3' untranslated regions (UTRs) are highly conserved, and each dsRNA segment had 78–105and 84–306 bp of 5' and 3' UTRs, respectively. Each dsRNA segment contained a single open reading frame (ORF). Computer analysis of dsRNA-1 revealed a putative open reading frame (ORF) that shows high sequence identity with an RNA-dependent RNA polymerase (RdRp) containing eight conserved motifs. dsRNAs 2−5also each contain one putative ORF coding for products of unknown function. The sequences of FgV2 dsRNA-2and dsRNA-3 have significant sequence identity with Magnaporthe oryzae chrysovirus 1 (MoCV1) dsRNA-3and -4, respectively. When compared to other dsRNA mycoviruses in a phylogenetic analysis of the putative RdRp protein, FgV2 was found to form a distinct virus clade with Aspergillus mycovirus 1816 and MoCV1 in the family Chrysoviridae.

        • KCI등재

          Genetics in Diabetes Mellitus - Contribution to the Classification and Management

          유지숙 대한소아내분비학회 2012 Annals of Pediatirc Endocrinology & Metabolism Vol.17 No.4

          Diabetes mellitus (DM) can be classified as type 1, type 2, and other specific types according to the underlying causes. Other specific types include genetic defects of β-cell function, insulin action, and other genetic syndromes associated with diabetes. Most childhood diabetes has been thought of as type 1 diabetes mellitus (T1DM), but the incidence of type 2 (T2DM) in childhood is rapidly increasing and it can be caused by monogenic defect. In some cases, it might not be easy to determine the type of diabetes and to choose the appropriate treatment. Many susceptible genes to the development of T1DM, T2DM as well as the causative genes of the monogenic diabetes have been identified due to the development of genome-wide association studies,candidate gene analysis and familial linkage studies. Study of the genetic factors in diabetes mellitus is valuable because it enables more appropriate management, and better prediction of disease progression. Therefore, it is important to consider the genetic factors in the management of childhood diabetes.

        • KCI등재

          무의미수화 따라하기에 나타난 농 아동의 수화소 특성

          유지숙,김화수 이화여자대학교 특수교육연구소 2013 특수교육 Vol.12 No.1

          수화 언어 습득을 이해하기 위해서는 다양한 음운론적 습득에 대한 이해가 필요하나 국내에서 이를 살펴보는 연구들을 찾아보기 어렵다. 본 연구는 수화소 습득에 대한 이해를 증진시키고 관련된 기초자료를 축적시키는 데 이바지하기 위한 목적으로 수행되었다. 이에 본 연구에서는 양쪽 귀 모두 90dB HL 이상 청력 손실이 있는 6~10세 사이의 농 아동 8명을 대상으로 무의미수화 따라하기 과제를 적용함으로써 수화소의 습득을 알아보았다. 또한 REVT의 수용어휘력검사를 수정․보완하여 수화로 전환시킨 어휘이해능력을 측정하고 무의미수화 따라하기 수행 능력과의 상관을 살펴보았다. 연구 결과 첫째, 수화의 조동적 복잡성 수준이 높아질수록 농 아동의 무의미수화 따라하기 수행점수가 낮아졌으며, 수준 간 유의미한 차이가 있었다. 특히, 수준1-수준4, 수준2-수준4, 수준3-수준4에서 수행점수 차이가 통계적으로 유의하였다(p<.001). 둘째, 수화소의 유형에 따른 수화소 따라하기 수행을 분석한 결과, 수형-내부적수동, 경로수동-내부적수동 간에 따라하기의 수행점수 차이가 통계적으로 유의하였다(p<.001, p< .01). 즉, 농 아동들은 수화가 조동적으로 복잡해질수록 습득에 어려움을 보이며 수화소를 습득할 시 내부적수동을 습득하는 데에서 가장 많은 어려움을 가지는 것으로 나타났다. 셋째, 무의미수화 따라하기 수행능력과 수화 이해능력 간의 상관관계를 분석한 결과 정적 상관관계가 유의하였다(p<.05). 이는 무의미수화 따라하기 수행 능력이 어휘 이해 능력과 연결되며 어휘 이해 능력과 무의미수화 따라하기 수행 능력이 서로를 예측할 수 있는 중요한 요인이 될 수 있음을 보여준다 The purpose of this study was to understand the acquisition of sign language and to accumulate the basic data of cheremes acquisition. In order to achieve this purpose, this study use the nonsign repetition task for 8 Deaf Children at aged 6-10. Hearing loss degree of participants was upper than 90dB HL. The children’s receptive vocabulary was assessed by vocabulary test with sign which was developed by modifying and complimenting receptive vocabulary test of REVT. And this study investigated the relationship between nonsign repetition ability and vocabulary ability of sign language using performance score of each test. The central findings were as follows: First, The more complex the level of phonetic complexity of handshape and movement, the deaf children’s repetition accuracy has been lowered. Specially, there were significant differences statistically in performance score between level 1 and level 4, between level 2 and level 4 and between level 3 and level 4(p<.001). Second, Analysis of the results of cheremes repetition performance according to chereme’s type, performance score differences were statistically significant between handshape and internal movement and between path movement and internal movement(p<.001, p<.01). In other words, The more complex cheremes(handshape and movement), deaf children had difficulties in acquiring signs and when children’s cheremes acquisition, they have many difficulties in internal movement acquisition. Third, deaf children’s performance ability of nonsign repetition correlated significantly with ability to understand the vocabulary of sign language(p<.05). It show that nonsign repetition skills is associated with the ability of vocabulary comprehension and that this two abilities could be factors which predict to each other.

        • KCI등재

          Endocrine disorders and the neurologic manifestations

          유지숙 대한소아내분비학회 2014 Annals of Pediatirc Endocrinology & Metabolism Vol.19 No.4

          The nervous system and the endocrine system are closely interrelated and both involved intimately in maintaining homeostasis. Endocrine dysfunctions may lead to various neurologic manifestations such as headache, myopathy, and acute encephalopathy including coma. It is important to recognize the neurologic signs and symptoms caused by the endocrine disorders while managing endocrine disorders. This article provides an overview of the neurologic manifestations found in various endocrine disorders that affect pediatric patients. It is valuable to think about ‘endocrine disorder’ as a cause of the neurologic manifestations. Early diagnosis and treatment of hormonal imbalance can rapidly relieve the neurologic symptoms. Better understanding of the interaction between the endocrine system and the nervous system, combined with the knowledge about the pathophysiology of the neurologic manifestations presented in the endocrine disorders might allow earlier diagnosis and better treatment of the endocrine disorders.

        • KCI등재후보

          공기식 PVT 컬렉터에 적용된 타공 베플의 변수에 따른 열 성능 향상을 위한 연구

          유지숙,김진희,김준태 한국태양에너지학회 2019 한국태양에너지학회 논문집 Vol.39 No.6

          Photovoltaic thermal (PVT) collectors are devices that simultaneously produce electricity and heat. Research on conventional air-type PVT collector focuses on installing baffles to enhance the collector's thermal performance. However, the baffles have pressure drop inside the collector which degrades the thermal performance. Thus, it is necessary to design baffles to smoothen the flow inside the air-type PVT collector. Alternatively, installing perforated baffles in air-type PVT collectors can reduce the collector weight, but parameters such as the diameter of the perforated holes and the height of the perforated plates should be considered. Therefore, the main aim of this study was to analyze thermal characteristics of each variable of perforated baffles installed inside air-type PVT collector. For this purpose, the uniformity of air flow in the collector was compared through NX program, and the resultant heat gain and thermal efficiency of the air-type PVT collector were compared and analyzed. Therefore, the main aim of this study was to analyze thermal characteristics of each variable (Baffle angle, length, height, pitch, perforated ratio) of perforated baffles installed inside air-type PVT collector. For this purpose, the uniformity of air flow in the collector was compared through CFD program, and the resultant heat gain and thermal efficiency of the air-type PVT collector were compared and analyzed. As a result, the maximum outlet temperature was increased by 1.45 times and the heat gain was increased by 193.8 Wth, depending on the perforated baffle plate, compared to the collector without the baffle. The heat transfer performance showed that the maximum internal velocity was 1.61 times higher and the Reynolds number was 1.06 times higher depending on the parameters of the baffle plate.

        • 무의미수화 따라하기에 나타난 농 아동의 수화소 특성

          유지숙,김화수 국제다문화의사소통학회 2012 국제다문화의사소통학회 학술대회 Vol.2012 No.11

          본 연구는 좋은 쪽 귀의 청력이 90dB HL 이상인 6~10세의 수화를 사용하는 농 아동 8명을 대상으로 하여 무의미수화 따라하기 과제를 적용함으로써 수화소(수동, 수형)의 습득을 알아보았다. 또한 REVT 의 수용어휘력검사를 수정․보완하여 수어어휘 이해능력을 측정하고 무의미수화 따라하기 수행 능력 과의 상관을 살펴보았다. 연구 결과, 첫째, 먼저 농 아동들은 수화에 포함된 수형과 수동이 음성적으로 복잡할수록 따라하기 정확성이 낮아졌다. 특히, 수준1-수준4, 수준2-수준4 간의 수행점수 차이가 통계 적으로 유의하였다(p<.01, p<.05). 둘째, 수화소의 유형에 따른 수화소 따라하기 수행을 분석한 결과, 수형-내부적수동, 경로수동-내부적수동 간에 따라하기의 수행점수 차이가 통계적으로 유의하였다 (p<.05, p<.01). 즉, 농 아동들은 수화소(수형, 수동)가 복잡해질수록 습득에 어려움을 보이며, 수화소를 습득할 시, 내부적수동을 습득하는 데에서 많은 어려움을 가진다는 것으로 해석할 수 있다. 셋째, 무의 미수화 따라하기 수행능력과 수어어휘 이해능력 간의 상관관계를 분석한 결과, 정적 상관관계가 유의 하였다(p<.05). 이는 무의미수화 따라하기 수행 능력이 어휘 이해 능력과 연결되며, 어휘 이해 능력과 무의미수화 따라하기 수행 능력이 서로를 예측할 수 있는 중요한 요인이 될 수 있음을 보여준다. This study considered cheremes(handshape and movement)acquisition using the nonsign repetition task for 8 Deaf Children at aged 6-11. Hearing loss degree of participants was upper than 90dB HL. The children's receptive vocabulary was assessed by vocabulary test with sign which was developed by modifying and complimenting receptive vocabulary test of REVT. And this study investigated the relationship between nonsign repetition ability and vocabulary ability of sign language using performance score of each test. The central findings were as follows: First, The more complex the level of phonetic complexity of handshape and movement, the deaf children's repetition accuracy has been lowered. Specially, there were significant differences statistically in performance score between level 1 and level 4 and between level 2 and level 4(p<.01, p<.05). Second, Analysis of the results of cheremes repetition performance according to chereme's type, performance score differences were statistically significant between handshape and internal movement and between path movement and internal movement(p<.05, p<.01). In other words, The more complex cheremes(handshape and movement), deaf children had difficulties in acquiring signs and when children's cheremes acquisition, they have many difficulties in internal movement acquisition. Third, deaf children's performance ability of nonsign repetition correlated significantly with ability to understand the vocabulary of sign language(p<.05). It show that nonsign repetition skills is associated with the ability of vocabulary comprehension and that this two abilities could be factors which predict to each other.

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