腸收縮機能에 미치는 Diazepm의 影響

林良洙,朴海根 충남대학교 의과대학 지역사회의학연구소 1987 충남의대잡지 Vol.14 No.2

This study was carried out to determine the effect of diazepam on the isolated intestinal smooth muscles. The intestinal mucle strips were prepared from mouse duodenum (about 2cm long) and were arranged isometrically, in vitro. Intestinal motility was recorded on a Physiograph (Four-A, Narco Biosystem) with force transducer (F-60) by means of Magnus method in Lock's solution. Diazepam significantly inhibited (p<0.001) the contractility of isolated smooth muscle in concentration of 0. 02, 0. 04, 0. 05, and 0.08mg/ml by dose dependently, and ceased the contraction in the concentration of 0.08mg/ml, and the effect of diazepam was not affected by presamina(10^-6M) propranolol (10^-4M), hexamethonium (10-5M), and acetylcholine (10-4b1). Diazepam inhibited the K^+-induced contraption by dose dependently and also in Ca^++-free Lock's solution, and effect of diazepam (0.08mg/ml) on muscle contraction was same pattern by the, effect of verapamil (10-7M). Diazepam (0.08mg/ml) decreased ^45Ca^++-uptake by the isolated intestinal muscle strip significantly (p<0.05) but more potent effect was observed by verapamil (10^-7M). These results suggested that diazepam inhibited the contractility by inhibiting the Ca++ movement by means of direct interaction with receptor in the muscle membrane.

Improved Micropropagation of Root Chicory, Cichorium intybus L. var. sativus.

Lim,Jung-Dae,Yang,Deok-Chun,Lee,Hyeon-Yong,Kim,Jong-Dai,Lee,Jin-Ha,Sung,Eun-Soo,Yu Chang-Yeon 한국자원식물학회 2004 Plant Resources Vol.7 No.1

The establishment of an efficient protocol for plant regeneration and micropropagation from leaf explant cultures of Chicory, Cichorium intybus L. var. sativus. is reported. Callus formation rate appeared 100% from explant in all growth regulators, but calli formed in the prensence of naphthaleneacetic acid (NAA) were appeared very compact and non-embryogenic state. The regenerated shoots were obtained from leaf explant cultures on solid MS medium containing different concentrations of cytokinins and auxin. The highest number of shoots (5.7) per explant and shoot growth (2.8cm) was obtained on MS medium containing 0.1 mg BAP L^-1 and 0.1 mg NAA L^-1. Indole acetic acid was the most suitable auxin for root formation among three auxins tested. 2,4-D had no effect on shoot and root formation.

한국판 섬망 평가 척도-98(K-DRS-98)의 표준화 연구

임경옥,김수영,이양현,이선우,김정란 大韓神經精神醫學會 2006 신경정신의학 Vol.45 No.6

Objective : This study was conducted to develop and to validate the Korean version of Delirium Rating Scale-Revised-98(K-DRS-98), which is a scale for diagnosing delirium and evaluating its severity. Method : After developing the K-DRS-98, 102 patients were rated by it among 4 diagnostic groups, such as delirium (N=25), dementia (N=27), schizophrenia (N=25) and others (N=25). To test for reliability, K-DRS-98 was independently administered by two psychiatrist. To test for validity, Korean version of Mini-Mental State Examination (MMSE-K) and Clinical Global Impression (CGI) were administered simultaneously. Statistical analysis was done with SPSS window version 12 package and statistical significance was p<0.05. Result : Intemal consistencies (Cronbach α) of two raters were 0.867 and 0.858, respectively. Inter-rater reliability (κ) was 0.893 for severity items of K-DRS-98 and κ value of diagnosis items was 0.969. In Delirium group, Pearson correlation Coefficients (r) of K-DRS-98 were -0.682 for MMSE-K and 0.667 for CGI. In comparison Delirium group with Others, ANOVA post hoc multiple comparison LSD was statistically significant (p<0.001). The cutoff score to diagnosis of delirium can be recommended 16 for seventy items and 21.5 for total score, respectively. Conclusion : The K-DRS-98 was showed good reliability and validity for the assessment of delirium. The K-DRS-98 is an easy and useful tool for diagnosing delirium and assessing its severity.

칼슘제 수관살포가 참다래의 과실 품질과 저장에 미치는 영향

임경호,나양기,임동근,마경철,조윤섭,김월수,이상현,박용서 全南大學校 農業科學技術硏究所 2001 農業科學技術硏究 Vol.36 No.-

This study were carried out to improve Kiwifruit quality and storage life. Three kinds of calcium compound were sprayed and calcium content of fruits, weight loss during fruit storage and fruit quality were investigated. Calcium contents within leaves and fruit were lower in Clef-non treatment than that of control. The calcium content in fruit pericarp of Kalk-H and CaCl2 was 0.04 to 0.05% higher than that of control. Fruit weight and soluble solids content at harvest was a little higher but acidity and fruit hardness was lowered. Fruit weight loss of Kalk-H and CaCl2 treatment was 1.39 to 1.53% lower than that of control during storage. The soluble solids of ripen fruit was 1.0 to 1.3% higher in all treatment and 0.8% higher in Kalk-H treatment in 120 of after storage. Fruit hardness of control fruit was higher at harvest but that of CaCl2 treatmented fruit was 0.39㎏/φ 5㎜ higher in 120 days of storage.

복숭아 품종별 경지 삽목에 있어서 삽수기부의 Wounding이 발근 및 활착에 미치는 영향

林敬鎬,金炳三,金月洙,羅良基,鄭淳柱 전남대학교 농업과학기술연구소 2000 農業科學技術硏究 Vol.35 No.-

The effect of wounding method on rooting and field adaptation was studied in 'Sunaga Wase' peach and several cultivars in order to establish mass production system of rooted cutting. Rooting was more than 90% in 'Sunaga Wase', 'Kurakata wase', 'Wolbongjosaeng' and 'Wolmijosaeng', and Root number, weight and length showed similar tendency, however, taking root in field was the highest, as much as 75.8% 'in Sunaga Wase'. Modified wounding tool (MWT) was more effective than current method because rooted cutting with MWT showed high root growth including rooting, root number, root weight and saved wounding time.

철강업체와 용접봉 제조업체에 근무하는 생산직 근로자의 직업성 요통 유병률과 관련 요인

임현술,김수근,김덕수,김두희,이종민,김양호 大韓産業醫學會 1999 대한직업환경의학회지 Vol.11 No.1

A cross-sectional study was conducted for detecting the risk factors and to propose an effective control program for occupational low back pain. The subjects were 1,665 male production workers employed at a steel factory and a welding material manufacturing factory. The data were collected by a self-reported questionnaire and a medical examination with a rehabilitation specialist for ten days in September, 1997. The contents of the questionnaire were as follows: general characteristics, physical characteristics, employment status, type of work, working environment and the experience of low back pain. The number of cases with symptoms of occupational low back pain were 321, so the point prevalence was 19.3 persons/100 persons. The number of cases with a history of occupational low back pain for one year were 554, so the one year period prevalence was 33.3 persons/100 persons. The point and one year period prevalences of occupational low back pain showed no significant differences in age, marital status, educational level and body mass index. The point and one year period prevalences of occupational low back pain showed no significant differences in alcohol drinking, smoking, stretching exercise and regular exercise. The point and one year period prevalences of occupational low back pain were significantly higher in the unsatisfied group that the satisfied group (p<0.01). However, no significant differences were found among tenures and shift work. The point and one year period prevalences of occupational low back pain were significantly higher in the lifting of heavy materials group than the nonlifting group(p<0.01). However, no significant differences were found among posture of the waist and the working posture. Through the multivariate logistic regression, significantly associated factors with occupational low back pain were found to be dissatisfaction with job (point prevalence: OR=1.78, 95% CI: 1.21-2.61: one year prevalence : OR=1.76, 95% CI: 1.26-2.47), lifting of heavy materials(point prevalence OR=1.94 95% CI : 1.44-2.61; one year prevalence: OR=2.17, 95% CI : 1.70-2.77) and tenure (point prevalence : OR=1.03, 95% CI : 1.01-1.06; one year prevalence : OR=1.02, 95% CI : 1.00-1.05).

Benson's Group Additivity Method를 이용한 염화다환방향족 화합물의 열역학적물성치 평가와 생성반응경로에 관한 연구

임지선,박자영,원양수,최성필 嶺南大學校 環境問題硏究所 1995 環境硏究 Vol.15 No.1

도시폐기물 소각시설에서 다이옥신류는 chlorobenzene, chlorophenols, PCBs등의 염소성분이 포함된 방향족화합물과 함께 폐기물의 소각처리시 불완전 연소로 인해 주로 생성된다. 이들 다이옥신 생성에 대한 반응메카니즘의 예측에 필요한 다이옥신을 형성하는 전구물질인 분자 및 radical의 정확한 열역학적 물성치를 평가하기 위해 Benson's group additivity method에서는 고려되지 않는 Cl, F, OH, CH3등과 같은 2개 이상의 치환기가 결합된 방향족화합물에 대한 computer code인 THERM을 이용하여 엔탈피(Hf), 엔트로피(St), 열용량(Cp)을 평가하였다. 또한 이와 같은 열역학적 물성치 평가법의 신뢰성을 검토하기 위해 다양한 방향족화합물에 대한 실험적으로 측정된 문헌치와 평가치와의 절대오차는 para-cresol의 0.02kcal/mole에서 hexamethylbenzene의 3.46kcal/mole로 좁은 범위를 나타내었다. 또한 다이옥신을 생성하는 전구물질들의 열역학적 물성치를 THERM을 이용해 간접적으로 평가함으로써 다이옥신을 형성하는 주요 생성반응 경로에 대해 살펴본 결과는 다이옥신을 형성하는 기초반응(elementary reaction)중 욤소수가 많은 반응물질일수록 반응이 더 잘 일어남을 알수 있었다. Chlorinated dioxins are often observed in effluent from oxidation or incineration such as chlorobenzenes, chlorophenols and PCBs. It would be of significant value to have an accurate and fundamental understanding of the mechanism for dioxin formation, in addition to the knowledge of dioxin thermodynamic properties, in order to assist in the design of stategies to effectively control or reduce emissions of these compounds. Very little has been published on the thermodynamic properties and elementary reactions which lead to formation of dioxins. Benson group additivity method, when used for the estimation of thermodynamic properties of molecules, does not account for all interactions between functional groups or atoms on aromatics, such as chlorines, hydroxyl or ether linkages. Therefore thermodynamic properties of dioxins are estimated by THERM based on Benson's group additivity method corrected by interactions group. Absolute errors between our predictions and literature values range from a low of 0.02 kcal/mole for paracresol to a high 3.46kcal/mole for hexamethylbenzene. We use these thermodynamic calculations to show the feasibility of several elementary reaction pathways leading to dioxin formation, where the presence of chlorine acts to enhance or lower the Gibbs free energy of reactions.

아고용한 Zr-Nb 2원계 합금의 미세조직 및 부식특성

林潤洙,崔洋鎭,河憲永,魏明鏞 大田産業大學校 2000 한밭대학교 논문집 Vol.17 No.1

Effect of niobium content on the microstructure and corrosion characteristic of hypo-solubility in binary Zr-Nb alloys were studied. The specimens with 0.2 and 0.4wt.% of niobium were prepared under various annealing temperatures from 400℃ to 800℃ and times from 30 to 5.000 minutes after vacuum arc remelting. The microstructures behavior was observed by a polarized optical microscope. TEM and micro-vickers hardness tester. The recrystallization temperature of the alloys slightly increased with niobium content due to increase of activation energy. The grain growth of the alloys more 0.2 than 0.4 wt.% of niobium occured rapidly. The specimens for corrosion test were prepared by annealing with 590℃ for 2hr to be recrystallized and performed in distilled water at 360℃ using a static mini-autoclave and the corrosion characteristic was measured by weight gains with exposure time. With increasing Nb content from 0.2 to 0.4wt.% the corrosion resistance in Zr-xNb binary alloys decreased an d oxide structure was slowly transformed from tetragonal -ZrO2 to monoclinic-ZrO2.

열처리시 냉간가공된 Zircaloy-4합금의 미세조직 및 재결정 거동

林潤洙,崔洋鎭,鄭蓮眺,魏明鏞 大田産業大學校 1999 한밭대학교 논문집 Vol.16 No.1

Effects of heat-treatment on the microstructure and recrystallization behavior of cold-worked Zircaloy-4 were studied. We used 70% cold-rolled, thin strip specimens. Heat-treatment of the specimens were performed at temperatures between 300℃ and 800℃ for 30 to 5,000 minutes. The recrystallization behavior were observed by means of polarized optical microscopy and TEM. Hardness were measurement by Micro-victors hardness tester. As the annealing time increased, the temperature region of hardness drop moved to lower, because the recovery and recrystallization could occur in lower temperature. The recrysatllization of cold-worked Zircaloy-4 alloys was completed between 500℃ and 600℃ for 60 min. The size of recrystallized grain visibly increased at 800℃ for above 600 min. The activation energy(Q) for recrystallization of Zircaloy-4 alloys was determined by the time for constant fraction technique and it was 253KJ/mo1.

비가림 및 망사 시설재배가 참다래의 수체생육 및 과실품질에 미치는 영향

나양기,마경철,임동근,김병삼,임경호,김월수,이상현,박용서 全南大學校 農業科學技術硏究所 2001 農業科學技術硏究 Vol.36 No.-

This studies were conducted to investigate the effects of rain shelter and netting on the tree growth, fruit set fruit quality of kiwifruit (Actinidia deliciosa). In rain shelter and net house, shoot falling wasn't occurred by strong wind, and fruit set, fruit weight and also fruit malformation, side flowering increased at the same time. In rain shelter house the increment temperature forced blooming date and increased shoot length, leaf number and diameter but in net house these tendencies were not observed. Relative light intensity of rain shelter house was higher than that of net house with standard of field culture (relative light intensity: 100%). Soluble solid content was higher in rain shelter house, and acid content was higher in net house. With the effect of rain sheltering the occurrence of bacterial bloom rot and canker significantly decreased in both rain shelter and net house but insect injury increased. These data showed that rain shelter house is more suitable for kiwi fruit culture.