혼합액정(80CB+50CB)의 네마틱-스멕틱 A 상전이 근처의 네마틱상에서 휨 탄성상수(K₃)에 관한 광산란 실험연구

임동건,이민규,변영태,유영훈,김두철 濟州大學校 基礎科學硏究所 1990 基礎科學硏究 Vol.3 No.1

액정 8OCB(octyloxycyanobiphenyl)에 액정 5OCB(pentyloxycyanobiphenyl)를 무게비로 혼합하여 혼합액정 (8OCB+5OCB)을 만들었다. 이 혼합액정은 5OCB의 무게비에 따라 McMillan지수 (??)가 감소하였다. 그리고 Rayleigh 광산란 실험방법을 이용하여, 순수 8OCB와 혼합액정의 네마틱-스멕틱 A 상전이 근처의 네마틱상에서 산란된 빛의 세기를 온도와 함수로 측정하였다. 실험데이타 분석결과는 휨(bend) 탄성 상수에 비례하는 세로방향 상관거리(??)는 McMillan 지수에 관계없이 임계지수 ??=0.66±0.03을 갖고 발산하였다. 이 값은 de Gennes의 모델에서 제시된 ??=0.67과 일치함을 알수있다. By utilizing Rayleigh scattering technique, we have measured the temperature dependence of scattered light intensity near nematic to smectic-A phase transition point in the pure 8OCB(octyloxycyanobiphenyl) and its mixtures contaning 5, 10, 15 weight percentage of 5OCB(pentyloxycyanobiphenyl). From analysis of these data. it is found that the longitudinal correlation length (??) diverges with critical exponent ??=0.66±0.03 independent on McMillan parameter (??). This result is consistent with de Gennes model (??).

5세 남아의 Influenza 종격동기종 및 대엽성 폐렴 1례

오희성,한유진,연은경,선동신,송준환,박경배,박준수,김영통,남해선,최영진,김용배 순천향의학연구소 2009 Journal of Soonchunhyang Medical Science Vol.14 No.3S

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Taguchi Approach for Anti-heat Stress Prescription Compatibility in Mice Spleen Lymphocytes In Vitro

Xiao-yu Zhu,Gui-lin Cheng,Feng-hua Liu,Jin Yu,Yu-jie Wang,Tong-quan Yu,Jian-qin Xu,Ming Wang 대한약학회 2011 Archives of Pharmacal Research Vol.34 No.7

Heat stress (HS) may induce immunosuppression as well as inhibit the proliferation of lymphocytes. This study evaluated the effects on immune function of our prescription on splenic lymphocytes under HS as well as its compatibility. The effects of four herbal extracts from Agastache rugosa, Atractylodes lancea, Cortex Phellodendri, and Gypsum Fibrosum on heat treated splenic lymphocytes were investigated and the compatibility of the prescription was also explored by using the Taguchi method. This study revealed changes in proliferation by traditional Chinese medicines of splenic lymphocytes after HS. Proliferation in the HS group was significantly lower than the control group. Under HS, the effects of higher concentrations of Agastache rugosa (100 and 200 μg/mL), Atractylodes lancea (100 and 200 μg/mL), Cortex Phellodendri (50 and 100 μg/mL) and Gypsum Fibrosum (100 and 200 μg/mL) caused a significant increase on ConA/LPS-induced proliferation of lymphocytes than lower concentrations. We, therefore, conclude that the prescription of traditional Chinese medicines may recover splenic lymphocytes from the immunosuppression induced by HS. The Taguchi design, which allows rapid and high efficiency for the selection of the best conditions for our prescription on HS-treated splenic lymphocytes, demonstrated that Agastache rugosa (200 μg/mL), Atractylodes lancea (200 μg/mL), Cortex Phellodendri (100 μg/mL) and Gypsum Fibrosum (100 μg/mL)were the optimal conditions for the prescription. The validation experiment confirmed that our composition in optimum extraction conditions enhanced effects on ConA or LPS-stimulated lymphocytes under HS. The results showed that the Taguchi optimization approach is a suitable method for optimization of the composition of prescription.

Mutational Analysis of Key EGFR Pathway Genes in Chinese Breast Cancer Patients

Tong, Lin,Yang, Xue-Xi,Liu, Min-Feng,Yao, Guang-Yu,Dong, Jian-Yu,Ye, Chang-Sheng,Li, Ming Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.11

Background: The epidermal growth factor receptor (EGFR) is a potential therapeutic target for breast cancer treatment; however, its use does not lead to a marked clinical response. Studies of non-small cell lung cancer and colorectal cancer showed that mutations of genes in the PIK3CA/AKT and RAS/RAF/MEK pathways, two major signalling cascades downstream of EGFR, might predict resistance to EGFR-targeted agents. Therefore, we examined the frequencies of mutations in these key EGFR pathway genes in Chinese breast cancer patients. Methods: We used a high-throughput mass-spectrometric based cancer gene mutation profiling platform to detect 22 mutations of the PIK3CA, AKT1, BRAF, EGFR, HRAS, and KRAS genes in 120 Chinese women with breast cancer. Results: Thirteen mutations were detected in 12 (10%) of the samples, all of which were invasive ductal carcinomas (two stage I, six stage II, three stage III, and one stage IV). These included one mutation (0.83%) in the EGFR gene (rs121913445-rs121913432), three (2.50%) in the KRAS gene (rs121913530, rs112445441), and nine (7.50%) in the PIK3CA gene (rs121913273, rs104886003, and rs121913279). No mutations were found in the AKT1, BRAF, and HRAS genes. Six (27.27%) of the 22 genotyping assays called mutations in at least one sample and three (50%) of the six assays queried were found to be mutated more than once. Conclusions: Mutations in the EGFR pathway occurred in a small fraction of Chinese breast cancers. However, therapeutics targeting these potential predictive markers should be investigated in depth, especially in Oriental populations.

The Relationship Among Rumination, Coping Strategies, and Subjective Well-being in Chinese Patients With Breast Cancer: A Cross-sectional study

Yu Liu,Tong-tong Jiang,Tie-ying Shi 한국간호과학회 2020 Asian Nursing Research Vol.14 No.4

Purpose: To investigate the relationship between rumination, coping strategies, and subjective wellbeing(SWB) and test the mediating effects of coping strategies on rumination and SWB in patientswith breast cancer (BC). Methods: This cross-sectional study assessed rumination, coping strategies, and SWB using the GeneralWell-being Schedule, the Chinese Event-Related Rumination Inventory, and the Medical Coping ModesQuestionnaire in BC patients admitted to a tertiary general hospital in China. Results: SWB was positively associated with the total score for rumination (r ¼ .32, p < .01), deliberaterumination (r ¼ .75, p < .01), and confrontation (r ¼ .58, p < .01). The relationship between ruminationand SWB was mediated by confrontation (indirect effect ¼ .74). Conclusion: BC diagnosis can affect patient's SWB. These findings indicate that rumination andconfrontation have direct and indirect effects on SWB. Therefore, psychological interventions focused onimproving coping may increase SWB. Notwithstanding, larger longitudinal studies are needed to furtherexamine the relationship between cognitive processes, coping strategies, and SWB.

Differential response to abiotic conditions, predation risk, and competition determine breeding site selection by two anuran species

Tong Lei Yu,Yan Shu Guo 한국통합생물학회 2013 Animal cells and systems Vol.17 No.2

Sympatry of species has been a central debate in ecology for decades but the mechanisms that allow coexistence are still heatedly disputed. The main paradigms include the importance of abiotic conditions, predation risk, and competition as determinants of community structure. In this study, we investigated oviposition-site selection of two anuran species, Asiatic toads (Bufo gargarizans) and dark-spotted frogs (Pelophylax nigromaculata), which coexist in southwestern China. We sampled the abiotic and biotic attributes of 36 B. gargarizans breeding sites and 34 adjacent unused sites, and 30 P. Nigromaculata spawning sites and 36 nearby unused sites. Our results showed that these two anuran species differed in the use of the main habitat types. B. gargarizans selected larger spawning sites with low levels of disturbance, high dissolved oxygen content, and the presence of fish. Conversely, P. nigromaculata preferred smaller waterbodies that were shallow, clear, and free of fish and B. gargarizans tadpoles. We conclude that differential habitat use and differences in response to abiotic conditions, predation risk, and competition, contributes to facilitating local coexistence and high species diversity in pond communities.

Trusted Computing Dynamic Attestation Using a Static Analysis based Behaviour Model

Tong Li,Yang Lin,Xueyuan Kong,Yue Yu,Fajiang Yu 한국정보기술융합학회 2011 JoC Vol.2 No.1

The Feast of “Culture”

Yu Tong Xi,Yukun Lee 한국콘텐츠학회 2013 ICCC International Digital Design Invitation Exhib Vol.2013 No.-

전시참가업체의 관계편익이 전시회 만족과 충성도에 미치는 영향 - 전환비용의 매개효과를 중심으로 -

진우동 ( Yu Tong Chen ),소단단 ( Dan Dan Su ),김봉석 ( Bong Seok Kim ) 서울과학기술대학교 과학문화전시디자인연구소 2014 한국과학예술융합학회 Vol.16 No.-

본 연구의 목적은 전시회에 대한 관계편익(relational benefits)이 전시회 참가업체의 만족과 참가업체의 충성도에 미치는 영향관계와 전환비용이 그 사이에 어떠한 효과를 미치는 지를 파악하여 장기적으로 경쟁력과 수익성을 갖춘 전시회로 발전시키기 위한 전략적 시사점을 제공하고자 한다. 도출된 각 요인들을 바탕으로 관계편익, 전환비용, 만족도, 충성도에 대한 영향관계를 검증(연구가설 1~6) 한 결과, 관계편익 중 심리적 편익과 경제적 편익이 만족과 충성도에 유의한 영향을 미치는 것으로 나타났으며, 경제적 편익이 전환비용에 유의한 영향을 미치는 것으로 나타났다. 경제적 편익이 충성도에 직접영향을 나타냈고 전환비용이 그 사이에 직접효과 및 간접효과를 나타냈기 때문에 전환비용이 경제적 편익과 충성도의 사이에 매개효과가 있다고 할 수 있다. 마찬가지로 전환비용이 만족도과 충성도에 매개효과가 있다고 할 수 있으며 만족도도 심리적과 충성도 사이, 경제적 편익과 충성도 사이에 매개효과가 나타났다. 본 연구는 전시회 주최자가 관계편익을 관리해야 하는 궁극적인 목표를 규명하였다. 또한, 전시회 참가업체들이 관계편익을 지각한다는 것을 확인하였으므로, 전시회주최자들의 이러한 관계편익 지각은 참가업체에게 제공하는 서비스들을 통하여 관계고객 세분화 (relationship customer segmentation)가 가능하다는 것을 의미한다. The purpose of this research is to analyze how relational benefit about exhibition influences exhibition participating company`s satisfactory level and participating company`s loyalty and how switching costs`s influence on the relation. The purpose of the analysis is to provide the long term strategy for developing competitive and profitable exhibition. As the verified result on the influential relationship among relational benefit, switching cost, satisfactory level and loyalty based on generated each factor shows (research hypothesis 1~6): psychological benefit and economical benefit has influence on satisfactory level and loyalty, economical benefit has noticeable influence on switching cost, satisfactory level has noticeable influence on loyalty, and switching cost has noticeable influence on loyalty. Since the economical benefit and switching cost have showed direct or indirect influence on loyalty and switching cost, it would be safe to assume switching cost is acting as mediation between economical benefit and loyalty. Switching cost is mediation between satisfactory level and loyalty; satisfactory level is mediation between psychological benefit, and satisfactory level is acting as mediation between loyalty and economical benefit. This research has established the ultimate purpose why exhibition sponsor must manage the relational benefit. Since it is confirmed that exhibition participating companies override the relational benefit, relational customer segmentation is possible through service provided by participating companies.

[P3-220606] 식물매개 및 동물매개 기반의 치유농업 활동이 성인의 전전두엽 활성에 미치는 영향

오소라(Yu Tong Wu),김선옥(Seon-Ok Kim),최나윤(Na-Yoon Choi),유나연(Na-Yeon Yoo),김윤진,박신애(Sin-Ae Park) 인간식물환경학회 2022 인간식물환경학회 학술대회 Vol.2022 No.춘계