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거대첨규 콘딜로마로부터 속발된 음경암 1치험예 : A Case Report
김수현,정충식,노준,박도영,장대수 조선대학교 1994 The Medical Journal of Chosun University Vol.19 No.2
The giant condyloma or carcinoma-like condylima is relatively rare. Although the disease is considered clinically mailgant. the possiblity of maligant changes from them are controversial even among the investigators but cannot be entirely overlooked. Most authorists consider that they get the possibility of malignant change. A case of malignancy of the penis which have apparently been transformed from giant condyloma acuminatum of the penis is herein presented with review of literature.
李丁柱,金仁湖,姜光鏞,張敏守 慶尙大學校 기초과학연구소 1988 基礎科學硏究所報 Vol.4 No.-
Bi_2(M_0O_4)_3 single crystal was grown by Czochralski technique. From the UV-VIS spectrum and the IR spectra Bi_2(M_0O_4)_3crystal was turned out having a indirect absorption process with energy gap, 2.8eV and having complicate absorption edge with maximum value in vicinity of 1860cm^-1. According to the crystallographic point group(2/m) and monoclinic system,Bi_2(M_0O_4)_3 crystal has two Raman active modes(Ag, Bg mode). Thus, the evolution of Raman spectra with temperature corresponding to selected experimental configuration-x(zz)y (Ag-mode), x(yx)y(Bg-mode)-was observed. From photoluminescence experiment, a violet-fluorescent light was observed. But we had a difficulty in analyzing the broad -spectra detected actually.
Kim, Ji-Hee,Lee, Kwang-Soon,Lee, Dong-Keon,Kim, Joohwan,Kwak, Su-Nam,Ha, Kwon-Soo,Choe, Jongseon,Won, Moo-Ho,Cho, Byung-Ryul,Jeoung, Dooil,Lee, Hansoo,Kwon, Young-Guen,Kim, Young-Myeong Mary Ann Liebert 2014 Antioxidants & redox signaling Vol.21 No.18
<P>Aims: Hypoxia induces expression of various genes and microRNAs (miRs) that regulate angiogenesis and vascular function. In this study, we investigated a new functional role of new hypoxia-responsive miR-101 in angiogenesis and its underlying mechanism for regulating heme oxygenase-1 (HO-1) and vascular endothelial growth factor (VEGF) expression. Results: We found that hypoxia induced miR-101, which binds to the 3 ' untranslated region of cullin 3 (Cul3) and stabilizes nuclear factor erythroid-derived 2-related factor 2 (Nrf2) via inhibition of the proteasomal degradation pathway. miR-101 overexpression promoted Nrf2 nuclear accumulation, which was accompanied with increases in HO-1 induction, VEGF expression, and endothelial nitric oxide synthase (eNOS)-derived nitric oxide (NO) production. The elevated NO-induced S-nitrosylation of Kelch-like ECH-associated protein 1 and subsequent induction of Nrf2-dependent HO-1 lead to further elevation of VEGF production via a positive feedback loop between the Nrf2/HO-1 and VEGF/eNOS axes. Moreover, miR-101 promoted angiogenic signals and angiogenesis both in vitro and in vivo, and these events were attenuated by inhibiting the biological activity of HO-1, VEGF, or eNOS. Moreover, these effects were also observed in aortic rings from HO-1(+/-) and eNOS(-/-) mice. Local overexpression of miR-101 improved therapeutic angiogenesis and perfusion recovery in the ischemic mouse hindlimb, whereas antagomiR-101 diminished regional blood flow. Innovation: Hypoxia-responsive miR-101 stimulates angiogenesis by activating the HO-1/VEGF/eNOS axis via Cul3 targeting. Thus, miR-101 is a novel angiomir. Conclusion: Our results provide new mechanistic insights into a functional role of miR-101 as a potential therapeutic target in angiogenesis and vascular remodeling. Antioxid. Redox Signal. 21, 2469-2482.</P>
Risk factors and outcomes of bloodstream infections with metallo-β-lactamase-producing Acinetobacter
Kim, Yeon-a,Yong choi, Jun,Ki kim, Chang,Oh kim, Chang,Soo kim, Myung,Hoon choi, Suk,Sik chin, Bum,Hoon han, Sang,Sung lee, Han,Kyoung choi, Hee,Jin jeoung, Su,Goo song, Young,Hwa yum, Jong,Yong, Dong Informa UK (TaylorFrancis) 2008 Scandinavian journal of infectious diseases Vol.40 No.3
DESIGN OF A LOW-COST 2-AXES FLUXGATE MAGNETOMETER FOR SMALL SATELLITE APPLICATIONS
Su-Jeoung Kim,장영근,오화석,Byoung-Young Moon 한국우주과학회 2005 Journal of Astronomy and Space Sciences Vol.22 No.1
This paper addresses the design and analysis results of a 2-axes magnetometer forattitude determinationof small satellite. A low-cost and efcient 2-axes uxgatemag-netometer was selected as the most suitable attitude sensor for LEO microsatelliteswhich require a low-to-medium level pointing accuracy. An optimization trade-offstudy has been performed for the development of 2-axes uxgate magnetometer. Allthe relevant parameters such as permeability, demagnetization factor, coil diameter,corethickness,andnumberofcoilturnswereconsideredforthesizingofasmallsatel-lite magnetometer. The magnetometer which is designed, manufactured, and testedin-house as described in this paper satises linearity requirement for determining at-titude position of small satellites. On the basis of magnetometer which is designed inSpace System Research Lab. (SSRL), commercial magnetometer will be developed.
DEVEL OPMENT OF ULTRA-LIGHT 2 AXES SUN SENSOR FOR SMALL SATELLITE
Su-Jeoung Kim,장영근,오화석,Sun-Ok Kim,Byoung-Young Moon 한국우주과학회 2005 Journal of Astronomy and Space Sciences Vol.22 No.1
This paper addresses developmentof the ultra-lightanalog sun sensors for small satel-lite applications. The sun sensor is suitable for attitude determination for small satel-lite because of its small, light, low-cost, and low power consumption characteristics.The sun sensor is designed, manufactured and characteristic-tested with the target re-quirementsof. ..Æ FOV (Field of View) and pointingaccuracyof. .Æ . Since the sunsensor has nonlinearcharacteristics betweenoutputmeasurementvoltage and incidentangle of sunlight, a higher order calibration equation is required for error correction.The error was calculated by using a polynomial calibration equation that was com-puted by the least square method obtained from the measured voltages vs. anglescharacteristics. Finally, the accuracies of 1-axis and 2-axes sun sensors, which consistof 2 detectors, are compared.
IL - 5에 의해 활성화된 호산구가 폐섬유모세포에 의한 교원질 젤 수축에 미치는 영향
김유영,김윤근,이병재,민경업,조상헌,김상훈,박흥우,김상헌,이수연,전순영,정재원,장윤석 대한알레르기학회 2001 천식 및 알레르기 Vol.21 No.2
Background:Subepithelial fibrosis plays a major role in the development of irreversible airway obstruction in asthma. Eosinophils are major effector cells in allergic inflammation, and it has been suggested that eosinophil-derived mediators such as transforming growth factor-β (TGF-β) play a role in the pathogenesis of airway remodeling. Objective : The aim of this study was to evaluate whether eosinophils activated by IL-5 plays a major role in the collagen gel contraction by lung fibroblasts. Method : Various cell numbers of lung fibroblasts were cultured in collagen gels to determine the appropriate numbers of fibroblasts. Purified human peripheral blood eosinophils were activated by IL-5 for 3 days, and TGF-β Mrna expression was evaluated using semiquantitative RT- PCR. The cultured supernatants with or without TGF-β were added to the collagen gel media with lung fibroblasts, and collagen gel diameter was serially measured to evaluate collagen gel contraction. Results : The amount of collagen gel conion was significantly associated with the number of fibroblasts (p$lt; 0.05), and TGF-β significantly contracted the collagen gel to contract in a dose-dependent manner (p$lt; 0.05). However, supernatants derived from IL-5-activated eosinophils did not contract the collagen gel compared to controls (p$gt; 0.05). Moreover, expression of TGF-β Mrna in eosinophils was the same before and after stimulus of IL-5. Conclusion: Activated eosinophils by IL-5 may play a minor role in the collagen gel contraction by lung fibroblasts.