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      • 콘크리트 덧씌우기 전후 비교조사에 따른 덧씌우기공법의 지지력 및 하중전달 특성 연구

        권순민,서영찬 漢陽大學校 工學技術硏究所 1997 工學技術論文集 Vol.6 No.1

        A 290m 2-lane experimental concrete overlay was constructed in 88 Express Highway to investigate it's feasibility in Korea. The test section consists of both bonded and unbonded type overlays. Pavement condition of the existing slab was surveyed before overlay, and construction feasibility of concrete overlay was checked during construction. After overlay, delamination, crack, deflection(using FWD), and load transfer at various temperature conditions have been measured periodically. Findings from the study can be summarized as follows. (1) The overlays performed successfully during at least 1 year after construction, (2) Overlay reduced deflection by 47% in bonded overlay section and by 57% in unbonded overlay section, (3) Unbonded overlay showed better load transfer than bonded overlay, (4) Joints transfer dowel bar showed better load transfer than those without dowel bar, and (5) Load transfer efficiency varied with temperature conditions.

      • KCI등재후보

        재해성 요추 추간판 탈출증의 역학 및 임상적 연구 : 비재해성 추간판 탈출증과 비교분석

        권순용,이승구,장일석,김지홍,임영 대한산업의학회 2000 대한직업환경의학회지 Vol.12 No.2

        Objectives : The purpose of study was to define the clinical and epidemiological factors of HNP and to provide the meaningful sources for establishing a prognosis and a rationale for clinical management of occupational low back problem. Methods : This study was performed at eight branch hospitals of Catholic University of Korea and several governmental hospitals for occupational disorders around the Kyunggi province of Korea since Jan. 1985. We analyzed the several factors about lumbar HNP through comparative study of the hospital admission series of each 200 patients in both occupation- and nonoccupation related, subjected to epidemiologic and clinical investigation, respectively. Results : 1. Mean age of occupational HNP was younger (30.9±8.8) than non-occupational HNP (35.2±10.5) (p〈0.05). 2. The duration of clinical symptom before admission was longer in non-occupational HNP(19.9±22.8 Mo.) than in occupational HNP(6.9±12.4 Mo.) (p〈0.05). 3. The symptomatic attack before admission was more frequent in non-occupational HNP(3.7±1.9) than in occupational HNP(2.5±0.9) (p(0.05) 4. There were no significant differences in physical findings between two groups, except for low rate (63%) of straight leg raising test (SLR) limitation in occupational HNP compared to non-occupational HNP(83%) (p〈0.05). 5. Even though The main reason for operative intervention was a failure of conservative treatment in both groups (p〈0.05), extruded subligamentous type was predominant(50%) in occupational HNP (p〈0.05), whereas extruded transligamentous type occupied major portion (67.8%) in non-occupational HNP (p〈0.05). Conclusion : The clinical results were poor in occupational HNP in both conservative and operative management groups, compared to non-occupational HNP (p〈0.05) and mean durations admission and re-admission rate was higher in occupational HNP, compared to non-occupational HNP (p〈0.05).

      • Cantharis의 세포독성

        殷載淳,權鎭,全焄,吳贊鎬,蘇俊魯 우석대학교 의약품개발연구소 1996 藥學硏究誌 Vol.1 No.-

        The cytotoxicity of cantharidine(CTD), the main component of Cantharis, and the combined effect of CTD and anti-tumor drugs on HeLa. Hep G2,SK-OV3. KOHS-NP, BALB/c 3T3 cells, mouse splenocytes and human lymphocytes were estiated by MTT colorimetry assay. CTD inhibited the proliferation of anti-tumor cells, BALB/C 3T3, mouse spleen cells and human lymphocytes. CTD increased the cytotoxicity of mitomycin C, cisplatin or mercaptopurine on tumor cells and BALB/c 3T3 cells. These results indicate that cantharidine has the cytotoxicity of tumor cells, fibroblast cells and immunocytes.

      • 사군자탕이 L1210 세포를 이식한 마우스의 면역세포에 미치는 영향

        殷載淳,金大根,柳東和,權鎭,徐龍勳,蘇俊魯,全焄,吳贊鎬 우석대학교 의약품개발연구소 1997 藥學硏究誌 Vol.2 No.-

        The purpose of this research was to investigate effects of Sa-Kunja-Tang(SKT) on immune cells of L1210 cell-transplanted mice. The apoptosis and T lymphocytes subopoulation were tested using a flow cytometry, and the proliferation was tested using a MTT assay. Nitric oxide production from mouse peritoneal macrophage was tested using a Griess reagents, and the phagocytic activity of mouse peritoneal macrophage was tested using a lucigenin chemiluminescence. SKT suppressed apoptosis of T-lymphocytes induced by L1210 transplantation. SKT decreased nitric oxide production from mice peritoneal macrophages increased by L1210 transplantation, and the phagocytic activity decreased by L1210 transplantation. These results suggest that SKT suppresses T lymphocyte apoptosis and macrophage activity in L1210 transplanted mice.

      • 사군자탕이 항암제를 투여한 마우스의 면역세포에 미치는 영향

        殷載淳,金大根,柳東和,權鎭,洪鍾星,蘇俊魯,全焄,吳贊鎬 우석대학교 의약품개발연구소 1997 藥學硏究誌 Vol.2 No.-

        The purpose of this research was to investigate effects of Sa-Kunja-Tang(SKT) on immune cells of antitumor drugs administered mice. The apoptosis and T lymphocytes subpopulation were tested using a flow cytometry, and the proliferation was tested using a MTT assay. The administration of etoposide. vincristine or doxorubicin increased the apoptosis of T-lymphocytes, but the action of doxorubicin was decreased by the administration of SKT. The administration of etoposide or vincristine decreased helper T and cytotoxic T cells population of T lymphocytes, but the action of vincristine was recovered by the administration of SCT. The administration of etoposide, vincristine or doxorubicin decreased the proliferation of T-lymphocytes, but the action of doxorubicin was increased by the administration of SKT. These results suggest that SKT has a regulative function of T-lymphocytes in anti-tumor drugs administered mice.

      • L1210 세포증식에 대한 Glycyrrhizin의 억제작용 기전

        殷載淳,徐龍勳,權鎭,柳東和,吳贊鎬,蘇俊魯,全焄,黃甲洙 우석대학교 의약품개발연구소 1996 藥學硏究誌 Vol.1 No.-

        The purpose of this research was to investigate the mechanism of inhibitory action of Glycyrrhizin(GZ) on the proliferation of mouse leukemia cell-line, L1210 cells. The cytotoxic activity was tested using a colorimetric tertrazolium assay(MTT assay), the apoptosis was tested using flow cytometry. Nitric oxide(NO) production form mouse peritoneal macrophage was tested using a Griess method and the phagocytosis of human polymorphonuclear cells was tested using a lucigenin chemiluminescence. GZ ingibited the proliferation of L1210, BALB/c 3T3 cells and mouse thymocytes at 50 ug/ml/ GZ did not affect nitric oxide production from mouse peritoneal macrophages in vitro, but ingibited nitric oxide production from lipopolysaccharide and y-interferon treated macrophages. Macrophages of GZ-administered mice accelerated NO production. The proliferation of L1210 cells apoptosis of L1210 cells were induced by co-culture with macrophage of GZ-administered mice. The apoptosis of L1210 cells were induced by co-culture with macrophage of GZ-administered mice. GZ increased the phagocytosis of human polymorphonuclear cells. These results suggest that GZ inhibit the proliferation of L1210 cells not only as a direct cytotoxic agent o tumor cells, but also by the enhancement of NO production and phagocytic activity.

      • KCI등재

        初等敎師의 專門性과 養成大學의 敎科敎育

        장찬익,권순달,최낙준 서울교육대학교 2001 한국초등교육 Vol.13 No.1

        This paper premises that the teacher's performance is different depending on the subject matter in teacher education. The objects of this paper are as follows. At first, this research is reviewed how curriculums of three type teachers education colleges - eleven national universities of education. K national university of education, E womans university - in korea is operating. Secondly, Teacher's performance is interviewed by 26 teachers in 9 elementary schools. They had studied subject matters in each other colleges and universities for elementary teachers. Data is analyzed by triangulations. The results showed that 11 national university of education demands high a grades for student in order to get the certification of teacher. Those of both teachers colleges of university is low. But pre-service subject matter education does not satisfy all of teachers. They assert that curriculums are changed not theory but practical. methods. This study appears that teachers are cultivated the knowledge and teaching method of subject matter in pre-service education.

      • 구름베어링 설계용 Expert System 개발에 관한 연구

        김호룡,권순천 연세대학교 산업기술연구소 1990 논문집 Vol.22 No.2

        In the study, an expert system for the design of rolling bearings has been developed by using GURU which is expert system building tool and by constructing knowledge base which consist of rules and facts. The developed system is composed of three parts : the first one is the bearing selection part that recommands the correct combination of ball and roller bearing to support a shaft for a given set of operationg conditions, as initial stage of bearing design. After requesting the minimum amout of input data from the engineer, the second part calculates the parameters and compares with data-base which constains the specifications of bearing. If the results do not satisfy the selection criterion, the search process is repeated. When the malfunction occurs, the last part displays the causes of bearing failure and the countermeasures for correction. As the result of applying this algorithm to the several real design examples, the proper bearing combination and the bearing dimensions are obtained. Throuth inserting the expertise into the knowledge base, the conceptual design process which could not easily be manipulated by conventional CAD approach could be implemented in computer.

      • KCI등재후보

        대량의 각혈로 사망한 장티푸스 1예

        한상우,유진홍,권순석,김성훈,박지찬,홍은정,최경성,박용완,장준희,안지원,박유경,강지영,박상미,신완식 대한감염학회 2004 감염과 화학요법 Vol.36 No.5

        We experienced a 25 year-old male patient with typhoid fever complicated with massive hemoptysis. Pulmonary complication in typhoid fever is very rare and to our knowledge, there has been no report of hemoptysis as a main cause of death with this disease. We herein report a rare case of typhoid fever.

      • 백삼에 있어 수침처리가 체형 및 사포닌 함량에 미치는 영향

        한윤경,이이,이문순,권숙희,정찬문 충북대학교 연초연구소 2009 煙草硏究 Vol.22 No.-

        본 연구는 수침 처리가 백삼제품의 원형복원에 미치는 영향을 조사하여 백삼제품 제조에 사용한 원료수삼의 품질을 평가하기 위한 기초자료를 얻고자 수행하였던 바 결과를 요약하면 다음과 같다. 백삼의 수침처리는 원료수삼과 같은 수준으로 원형을 복원할 수 있어 제품에 사용된 원료수삼의 뇌두의 경흔적, 동체부위의 피해정도 그리고 내부조직의 나이테 관찰이 용이하여 연근판별 및 품질평가가 가능하였다. 백삼제품의 ginsenoside 함량은 제조회사에 따라 다소 차이가 있었으며 panaxadiol계 사포닌은 ginsenoside-Rb₁이 많고, panaxatriol계 사포닌은 ginsenoside-Rg₁이 높게 나타났다. 그리고 수침에 의한 백삼의ginsenoside 함량은 수침온도가 증가할수록 감소하는 경향이었다. This study was conducted to investigate the effects of soaking treatment in white ginseng and evaluated quality evaluation of raw ginseng and ginsenoside. Restoration to the original state of the raw ginseng can be achieved by soaking treatment in white ginseng. Stem vestige at rhizome and damage of main root of the swelled white ginseng was examined by eyes and annual rings by microscope easily. Soaking treatment made it easy to be examined the identification of root age and quality evaluation of white ginseng. The content of ginsenoside showed difference among the three products. The content of ginsenoside-Rb1 was highest among the constituents of protopanaxadiol saponin and the content of ginsenoside-Rg1 among that of protopanaxatriol saponin. The higher the soaking temperature was, the lower the content of ginsenoside in the white ginseng was.

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