자궁근종에서 Phospholipase C 동종효소들의 발현에 관한 연구

윤혜원,류임주,김창미,심재철,서영석 대한해부학회 1995 Anatomy & Cell Biology Vol.28 No.4

선천성 판상 피부 골종 1예

이미애,김진형,황규광,박혜진,조소영 대한피부과학회 1999 大韓皮膚科學會誌 Vol.37 No.7

Osteoma cutis is a rare, benign, frequently congenital tumor of the skin composed of bone tissue, showing neither invasive nor metastasizing tendency. The term osteoma cutis is applied to cases of primary cutaneous ossification in which there is no evidence of Albrights hereditary osteodystrophy. Congenital platelike osteoma cutis is a clinically different variant of primary cutaneous osteoma. We report the case of a 10-month-old male infant who presented with two walnut-sized firm, poorly demarcated plaques containing pinhead-sized erythematous papules on the abdomen and the right leg and multiple variably sized erythematous subcutaneous nodules on the left leg sinee birth. The initial lesions did not enlarge nor did new lesions develop. A biopsy specimen of the abdominal lesion showed bony plate and cartilaginous structures in the subcutaneous fat tissue. There was no history of any skin disease prior to the development of osteoma.

직업적 아크릴아미드 폭로에 의한 다발성 신경병증

정해관,권용욱,어경윤,김병준,양정선,정철,진영우,이미영,강성규 大韓産業醫學會 1998 대한직업환경의학회지 Vol.10 No.3

Authors report a first Korean case of polyneuropathy in an acrylamide producing factory together with an environmental and epidemiologic survey for the ten workers of the same workplace and 46 workers in the production and manufacturing acrylamide in Ulsan, Korea. The case is 30 years old man who worked in the production of the acrylamide for two years. In August, 1997, he had a weakness of the lower extremity with loss of body weight of 15 Kg which progressed to paresthesia of the limbs, the loss of vibration sense, difficulty in walking, speech disturbance, dysuria, constipation, difficulty in erection and swallowing difficulty. Neurologic examination showed a complete loss of vibration and position sense, and loss of deep tendon reflex in all the limbs. There was a contact dermatitis-like skin lesion on the feet. Electrodiagnostic test showed a generalized polyneuropathy of moderate degree involving motor and sensory component of peripheral and cranial nerves. After 8 months' cessation from exposure and supportive care, his symptoms were completely resolved, but abnormality in electrodiagnostic test and vibrotactile perception threshold still persisted, although much improved than before. There were 11 workers in the same workplace of the case, producing acrylamide by microorganism as a catalyst. Environmental monitoring of the workplace revealed air borne concentration of the acrylamide to be from 0.05 to 0.23 mg/m3 by personal sampling and from 7.65 to 11.65 mg/m3 by area sampling during filter exchanging process, which far exceeds TLV-TWA of 0.03 mg/m3. However, acrylamide was not detected from the plasma of the workers. Symptom questionnaire showed a markedly higher complain of neurologic symptoms, compared to the workers of the other acrylamide producing companies. Electrodiagnostic test showed a several workers are in the lower normal range without definite abnormality. Vibrotactile perception threshold by Vibratron Ⅱ showed a significantly increased threshold in the workers of the same workplace compared to the other acrylamide workers and significantly decreased test score of color vision compared to normal controls. After improvement of the production process and strict wearing of the protective device, most workers reported the improvement of clinical symptoms, but vibrotactile perception threshold was not improved. These result suggests the need for the effective environmental monitoring together with a periodic biological monitoring. Development of effective screening test is urgently needed to control and assess the skin absorption of acrylamide.

치과용 접착제가 복합레진 인레이와 레진시멘트의 결합력에 미치는 영향

송미혜,박수정,조현구,황윤찬,오원만,황인남 大韓齒科保存學會 2008 Restorative Dentistry & Endodontics Vol.33 No.5

본 연구는 레진시멘트의 레진인레이에 대한 접착 시 접착제 혹은 primer의 사용이 결합력에 영향을 미치는지 평가하기위해 시행하였다. 직경 5 mm,높이 4.5 mm의 원기둥 형태로 제작한 레진인레이(Tescera, Bisco, USA)의 표면을 1000번,1500번 그리고 2000번 사포로 주수 하에서 연마하여 평편한 면을 형성한 후 레진인레이의 표면에 sandblasting을 시행한 후 표면에 1분 동안 silane을 도포하였다. 2군으로 나누어 한 군은 대조군으로,다른 한 군은 표면에 동일한 제조사의 접착제나 프라이머를 도포한 후 중합하였다. 레진인레이 상에 3 mm 직경의 구멍이 형성된 아크릴판을 고정하고,구멍에 레진 시멘트를 주입하여 경화시켰다. 레진 시멘트는 Panavia-F(Kyrary), Varolink-II(Ivoclar-Vivadent), RelyX Unicem (3M ESPE),Duolink (Bisco)와 자가중합형인 Multilink(Ivoclar-Vivadent)를 사용하였다. 제작된 시편을 만능물성시험기에 위치시고 전단결합강도를 측정하였다. 측정 결과 접착제나 프라이머를 도포한 군은 대조군에 비해 전단결합강도가 증가하였다 (p < 0.05). 하지만 Variolink-II와 Panavia-F는 전단결합강도의 차이를 보이지 않았다. 대조군에서는 각 레진 시멘트 간에 전단결합강도의 유의한 차이를 보였으며 (p < O.O1),Variolink-II가 가장 높은 결합강도를 보인 반면,자가중합형인 Multilink가 가장 낮은 결합강도를 보였다. 하지만,접착제나 프라이머를 도포한 군에서는 각 제품 간에 전단결합강도의 차이를 보이지 않았다. 이상의 결과 이원중합형이나 자가중합형 레진시멘을 이용하여 레진인레이 부착 시 silane 처리 후 접착제나 프라이머의 도포가 결합 강도의 증가를 위해 필요하리라 사료된다. This study analyzed the influence of dental adhesive/primer on the bond strength between indirect resin composite and the resin cement. Seventy disc specimens of indirect resin composite (Tescera Dentin. Bisco) were fabricated. And bonding area of all specimens were sandblasted and silane treated for one minute. The resin cements were used with or without application of adhesive/primer to bonding area of indirect resin restoration: Variolink-II (Ivoclar-Vivadont): Exite DSC, Panavia-F (Kuraray): ED-Primer, RelyX Unicem (3M ESPE): Single-Bond. Duolink (Bisco): One-step. Mulitlink (Ivoclar-Vivadent): Multilinh Primer. Shear bond strength was measured by Instron universal testing machine. Adhesive application improved shear bond strength (p < 0.05). But Variolink II and Panavia-F showed no statistically significant difference according to the adhesive application. With the above results. when resin inlay is luted by resin cement it seems that application of dental adhesive/primer is necessary in order to improve the bond strength.

The Relationship between Empathy Ability and Work Consciousness according to the DISC Behavioral Types of Some Dental Hygiene Students

Mi-Hae Yun,Eun-Joo Na 대한예방치과학회 2023 International Journal of Clinical Preventive Denti Vol.19 No.4

Objective: This study analyzes the relationship between DISC behavior type, empathy, and career preference among dental hygiene students enrolled in the Department of Dental Hygiene, and analyzes factors that affect career preference. Methods: A survey was conducted on a total of 245 students attending the Department of Hygiene. Results: Empathy ability was found to be 3.54 for cognitive empathy and 3.42 for emotional empathy, and was similarly high in the stable and sociable types among the DISC behavior types. In terms of job preference, the D type and C type preferred honor, while the I type preferred aptitude and interest. The S type most strongly preferred stability and advancement. Conclusion: In terms of correlations, cognitive empathy was significantly positively correlated with affective empathy, interest in aptitude and interest, and preference for stability and advancement, and affective empathy was significantly correlated with preference for honor and preference for stability and advancement. Hierarchical regression was performed to investigatethe effects of each factor on job preference. Cognitive preference and DISC profiles affected job preference, but affective empathy did not affect job preference.

Clinical Study on 3-Year-Fluoride Iontophoresis Program for Lao Children

Mi-Hae Yun,Na-Young Kim,Eun-Joo Na,Ja-Won Cho 대한예방치과학회 2017 International Journal of Clinical Preventive Denti Vol.13 No.3

Objective: For the oral health promotion for Laos children, the fluoride application program as one of the important preventive project has been done for 3 years at Vientiane city in Laos, and the preventive effects were examined by oral examination. Methods: 2,146 of school children were participated divided with 2 groups as 1,127 of experimental group and 1,019 in the control group, at age 7 to 11 years, from the year 2013 to 2016, through supplying the 2% NaF was applied with the ion tophoresis method on the permanent molar teeth for the experimental group children, otherwise serve the oral health education as tooth-brushing instruction only for the control group children. 4 times oral examinations were done at before the program, a year later, 2 years later and 3 years later. The data was suggested every year and compared with the experimental group and the control, in order to estimate the preventive effect for fluoride application program. Results: Caries prevention effect was revealed as 34.4% in 3rd grade, −21.2% in 4th grade 15.8% in 5th grade estimated with DMFT index and compared with the control group, more over, 42.3%, 7.6%, and 49.4% of prevention effect measured by DMFS index. Conclusion: Fluoride applicaion program was effective to promote the oral health and contributed for the prevention of dental caries for Laos school children, so it was recommended to extend the program more widely in Laos.

Variations of Oral Cavity Environment according to Sodium Lauryl Sulfate of Dentifrice Containing Antimicrobial Agents

Mi-Hae Yun,Cheon-Hee Lee,Eun-Joo Na,Su-Kyung Jwa 대한예방치과학회 2013 International Journal of Clinical Preventive Denti Vol.9 No.2

Objective: In this study, SLS, which is a component of the interrupt made that contain Hyangyunje is Representative materials such as dry mouth, bad breath, causing a lot of controversy this not be combined and when combined with hyanggyunje Even penetration of the mouth, it was attempted to Yakunitato the interrupt agent many developments by examine the correlation between bad breath and mouth indexes or when it is not coupled when they are coupled. Methods: The study to compare the difference between the toothpaste JEGAN average, by performing sample T-test experiments among corresponding (paired t-test) over time for each to obtain the following results. Results: Results were compared hygiene index in the mouth of the control group interrupt zero after brushing with experimental group the results were compared to four weeks prior to experimentation the experimental group and control group, a statistically significant difference is generated from the one week experiment,Up to 4 weeks before the experiment in the case of groups, statistically there was no difference, and the difference when compared to the fourth week before the experiment toward that of the control group (p<0.05). Conclusion: It was confirmed that excel interrupts a combination of antimicrobial agents as a result of further research in the first lauryl sodium sulfate when it was ruled out in the oral cavity and a reduction in bad breath, and the humidity was increased in the oral cavity, oral cavity cleansing effect.

Validity and reproducibility of a food frequency questionnaire to assess dietary nutrients for prevention and management of metabolic syndrome in Korea

Yun-Jung Bae,Hae-Yeon Choi,Mi-Kyung Sung,Mi-Kyung Kim,Mi-Kyeong Choi 한국영양학회 2010 Nutrition Research and Practice Vol.4 No.2

Little data exists on metabolic syndrome (MetS) related with intake, especially for the South Korean. The purpose of this study was to develop and evaluate a food frequency questionnaire (FFQ) for nutritional assessment in the population with MetS in South Korea. Randomly selected female participants, mean age 21.9 years (n = 38) were invited to answer the FFQ twice (FFQ1 and FFQ2) over a nine-month interval and to complete twelve-day diet records (DR) during the months between in South Korea. The correlation coefficients for nutrient intake between FFQ1 and FFQ2 varied from 0.253 (niacin) to 0.573 (cholesterol), and the energy intake-adjusted correlation coefficients ranged from 0.187 for protein to 0.662 for iron. The energy intake-adjusted and de-attenuated correlation coefficients for comparison of FFQ1 and the DRs ranged between 0.277 (vitamin B₁) and 0.768 (fiber), and between 0.229 (zinc) and 0.859 (fat) for comparison of DRs with FFQ2. The percentages of study subjects classified into the same quartiles in both the DRs and FFQ1 ranged from 15.8% (vitamin B6) to 47.4% (calcium), and for the same quartiles in DRs and FFQ2 from 13.2% (vitamin B1) to 44.7% (potassium). The FFQ has reasonably good validity and reproducibility. Further research is needed for an assessment of reproducibility and validation of present FFQ in the subjects with MetS.

Issues pertaining to Mg, Zn and Cu in the 2020 Dietary Reference Intakes for Koreans

Hae-Yun Chung,Mi-Kyung Lee,Wookyoung Kim,Mi-Kyeong Choi,Se-Hong Kim,Eunmee Kim,Mi-Hyun Kim,Jung-Heun Ha,Hongmie Lee,Yun-Jung Bae,In-Sook Kwun 한국영양학회 2022 Nutrition Research and Practice Vol.16 No.no.sup1

In the current years, it has now become necessary to establish standards for micronutrient intake based on scientific evidence. This review discusses issues related to the development of the 2020 Dietary Reference Intakes for Koreans (KDRI) for magnesium (Mg), zinc (Zn), and copper (Cu), and future research directions. Following issues were encountered when establishing the KDRI for these minerals. First, characteristics of Korean subjects need to be applied to estimate nutrient requirements. When calculating the estimated average requirement (EAR), the KDRI used the results of balance studies for Mg absorption and factorial analysis for Zn, which is defined as the minimum amount to offset endogenous losses for Zn and Mg. For Cu, a combination of indicators, such as depletion/repletion studies, were applied, wherein all reference values were based on data obtained from other countries. Second, there was a limitation in that it was difficult to determine whether reference values of Mg, Zn, and Cu intakes in the 2020 KDRI were achievable. This might be due to the lack of representative previous studies on intakes of these nutrients, and an insufficient database for Mg, Zn, and Cu contents in foods. This lack of database for mineral content in food poses a problem when evaluating the appropriateness of intake. Third, data was insufficient to assess the adequacy of Mg, Zn, and Cu intakes from supplements when calculating reference values, considering the rise in both demand and intake of mineral supplements. Mg is more likely to be consumed as a multi-nutrient supplement in combination with other minerals than as a single supplement. Moreover, Zn-Cu interactions in the body need to be considered when determining the reference intake values of Zn and Cu. It is recommended to discuss these issues present in the 2020 KDRI development for Mg, Zn, and Cu intakes in a systematic way, and to find relevant solutions.

일부 여고생들의 구강보건지식 및 태도와 주관적인 구강건강상태와의 상관관계

윤미혜(Mi-Hae Yun),김민형(Min-Hyung Kim),민경혜(Kyoung-Hye Min) 융복합지식학회 2018 융복합지식학회논문지 Vol.6 No.2

본 연구는 일부 여고생의 구강건강지식도, 구강건강태도, 주관적인 구강건강상태를 파악하여 치과의료서비스로부터 구강관리가 소홀한 여고생들에게 적합한 구강보건교육 프로그램의 기초자료로 활용하기 위하여 일부 대전지역의 여고생을 대상으로 자기기입식 방법으로 설문조사를 실시하여 분석하였다. 구강건강지식도는 0.70점, 구강건강태도는 3.24점, 주관적 구강건강상태는 0.21점으로 낮게 나타났으며, 구강건강지식도는 성적이 좋을수록 높고, 구강건강태도는 구강보건교육을 경험한 여고생에게서 높게 나타났다. 구강건강지식도와 구취, 구강건강태도와 치아우식증이 통계적으로 유의하였다. 이에 여고생들에게 올바른 구강건강에 대한 자가인지도 및 상태를 파악하기 위한 구체적인 정보를 제공하며 지속적인 구강보건교육 프로그램을 적용할 필요가 있다고 사료된다. This study was conducted to investigate the oral health knowledge, oral health attitude, and subjective oral health status of female highschool students. For the female highschool students, who do not receive the sufficient oral care from the dental services, this research was analyzed to be utilized as the basic data for the oral health education programs effectively. The result came out accordingly: knowledge was 0.70, attitude was 3.24, and the subjective status was 0.21. The statistical data shows the significant considerations of oral health knowledge, bad breathing habit, oral health attitude, and dental caries. The results of this study imply that it is necessary to provide the female highschool students with specific information on the oral health program to be aware of their oral health attitude and oral health status. As a preventive program, it is essential to provide the educational programs to alert the female highschool students continuously.