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      • KCI등재

        Preparation and simulation performance of light carbon fiber paper-based electromagnetic shielding materials

        Liu Zhi,Liu Chenhui,Wang Yu,Mi Ruozhen,Gao Xueping 한국탄소학회 2024 Carbon Letters Vol.34 No.5

        The arrival of the 5G era has made electromagnetic pollution a problem that needs to be addressed, and flexible carbon-based materials have become a good choice. In this study, wet continuous papermaking technology was used to prepare carbon fiber paper (CFP) with a three-dimensional conductive skeleton network; Molybdenum disulfide (MOS2)/ iron (Fe) @ carbon fiber paper-based shielding material was prepared by impregnating and blending molybdenum disulfide/iron (MOS2/Fe) phenolic resin MOS2/ Fe@ CFP. The morphology, structure, electrical conductivity, mechanical properties, hydrophobicity, and electromagnetic shielding properties of the composite were characterized. The results show that the three-dimensional network structure based on a short carbon fiber paper-based conductive skeleton and the synergistic effect of the MOS2 dielectric wave absorbing agent and Fe magnetic wave absorbing agent have good electromagnetic shielding performance. Conduct electromagnetic shielding simulation using HFSS software to provide options for the structural design of CFP. The electromagnetic shielding performance of CFP reaches 70 dB, and the tensile strength reaches 34.39 MPa. Based on the mechanical properties, the compactness of carbon fiber paper is ensured. The lightning damage model test using CST software expands the direction for the use of carbon fiber paper. In summary, MOS2/Fe @CFP with excellent shielding performance has great application prospects in thinner and lighter shielding materials, as well as high sensitivity, defense and military equipment.

      • KCI등재

        近代时期中国短篇小说的内容试探

        劉美景(Liu Mi-Kyoung) 대한중국학회 2005 중국학 Vol.25 No.-

          Novels in China were recognized as the humble literature style and remained on the periphery for a long time. Getting to modern ages, novels were understood by the ways a save-the-nation drive and the Enlightenment and began to be written actively. Also novels occupied the central part of literature due to their diverse theories. Although the process was fairly unnatural, it aroused unprecedented development. Later it led to the birth of new novels of China after 4th May. It tried to study Zhuboshi; such as the social reality, wishes and anguish which they wanted to include by exploring novel theories and real creation of short stories which were actively discussed at that time.

      • KCI등재

        수직 시각에서 도시 건축 사진의 시지각 법칙 분석 - 홍콩 건축 사진을 중심으로 -

        유미 ( Liu Mi ),양종훈 ( Yang Jong Hoon ),이상은 ( Lee Sang Eun ) 한국사진학회 2021 AURA Vol.0 No.46

        This study observes the vertical perspective methods in urban architectural photography and takes Hong Kong building images as an example to explore the rendering method and effect based on the theory "Gestalt Laws of Organization" of Gestalt psychology. In the observation of building images with a vertical perspective, the authors first group the subjects by the shooting perspectives (a vertical front view or a vertical upward view), then, based on the Gestalt Laws of Organization, draw the conclusion about the role of shooting perspective in image composition as well as justifying the use of such perspectives in building images. The study shows, building images with a vertical front view are more flat, which feature will enhance the Equality of the forms of visual elements, and further take the advantages of the Gestalt Laws of Organization to connect these elements to realize an order-based coherence. While for building images with a vertical upward front view, the Law of Figure-ground is used as a major tool to define the visual hierarchy of the buildings and the sky, then create a perspective and gradient effect through the Law of Continuity and Law of Proximity to further improve the "three-dimensional rendering" and "spatial rendering". The study justifies the usage of vertical perspective in building photography, and the exploration and in-depth study of Gestalt Laws in building images could facilitate the understanding of connotations in the image composition.

      • KCI등재

        Loss of MicroRNA-137 Impairs the Homeostasis of Potassium in Neurons via KCC2

        Ting-Wei Mi,Xiao-Wen Sun,Zhi-Meng Wang,Ying-Ying Wang,Xuan-Cheng He,Cong Liu,Shuang-Feng Zhang,Hong-Zhen Du,Chang-Mei Liu,Zhao-Qian Teng 한국뇌신경과학회 2020 Experimental Neurobiology Vol.29 No.2

        Neuropsychiatric disorders are the leading cause of mental and intellectual disabilities worldwide. Current therapies against neuropsychiatric disorders are very limited, and very little is known about the onset and development of these diseases, and their most effective treatments. MIR137 has been previously identified as a risk gene for the etiology of schizophrenia, bipolar disorder, and autism spectrum disorder. Here we generated a forebrain-specific MIR137 knockout mouse model, and provided evidence that loss of miR-137 resulted in impaired homeostasis of potassium in mouse hippocampal neurons. KCC2, a potassium-chloride co-transporter, was a direct downstream target of miR-137. The KCC2 specific antagonist VU0240551 could balance the current of potassium in miR-137 knockout neurons, and knockdown of KCC2 could ameliorate anxiety-like behavior in MIR137 cKO mice. These data suggest that KCC2 antagonists or knockdown might be beneficial to neuropsychiatric disorders due to the deficiency of miR-137.

      • KCI등재

        Ginsenoside Re Inhibits Osteoclast Differentiation in Mouse Bone Marrow-Derived Macrophages and Zebrafish Scale Model

        Park, Chan-Mi,Kim, Hye-Min,Kim, Dong Hyun,Han, Ho-Jin,Noh, Haneul,Jang, Jae-Hyuk,Park, Soo-Hyun,Chae, Han-Jung,Chae, Soo-Wan,Ryu, Eun Kyoung,Lee, Sangku,Liu, Kangdong,Liu, Haidan,Ahn, Jong-Seog,Kim, Y Korean Society for Molecular and Cellular Biology 2016 Molecules and cells Vol.39 No.12

        Ginsenosides, which are the active materials of ginseng, have biological functions that include anti-osteoporotic effects. Aqueous ginseng extract inhibits osteoclast differentiation induced by receptor activator of NF-${\kappa}B$ ligand (RANKL). Aqueous ginseng extract produces chromatography peaks characteristic of ginsenosides. Among these peaks, ginsenoside Re is a major component. However, the preventive effects of ginsenoside Re against osteoclast differentiation are not known. We studied the effect of ginsenoside Re on osteoclast differentiation, RANKL-induced tartrate-resistant acid phosphatase (TRAP) activity, and formation of multinucleated osteoclasts in vitro. Ginsenoside Re hampered osteoclast differentiation in a dose-dependent manner. In an in vivo zebrafish model, aqueous ginseng extract and ginsenoside Re had anti-osteoclastogenesis effects. These findings suggest that both aqueous ginseng extract and ginsenoside Re prevent bone resorption by inhibiting osteoclast differentiation. Ginsenoside Re could be important for promoting bone health.

      • KCI등재

        Folic acid supplementation regulates key immunity-associated genes and pathways during the periparturient period in dairy cows

        Khan Muhammad Zahoor,Zhang Zhichao,Liu Lei,Wang Di,Mi Siyuan,Liu Xueqin,Liu Gang,Guo Gang,Li Xizhi,Wang Yachun,Yu Ying 아세아·태평양축산학회 2020 Animal Bioscience Vol.33 No.9

        Objective: The current research was aimed to profile the transcriptomic picture of the peripheral blood lymphocytes (PBLs) associated with immunity in Chinese Holsteins supplemented orally with coated folic acid during the periparturient period. Methods: The total of 123 perinatal cows were selected for this study and divided into three groups; group A (n = 41, 240 mg/500 kg cow/d), group B (n = 40, 120 mg/500 kg cow/d) and group C (n = 42, 0 mg/cow/d) based on the quantity of folic acid fed. Three samples of PBLs were selected from each folic acid treated group (high, low, and control) and RNA sequencing method was carried out for transcriptomic analysis. Results: The analysis revealed that a higher number of genes and pathways were regulated in response to high and low folic acid supplementation compared to the controls. We reported the novel pathways tumor necrosis factor (TNF) signaling, antigen processing and presentation, Staphylococcus aureus infection and nuclear factor (NF)-kappa B signaling pathways) and the key genes (e.g. C-X-C motif chemokine ligand 10, TNF receptor superfamily member 1A, cluster difference 4, major histocompatibility complex, class II, DQ beta, NF-kappa-B inhibitor alpha, and TNF superfamily 13) having great importance in immunity and anti-inflammation in the periparturient cows in response to coated folic acid treatment. Conclusion: Collectively, our study profiled first-time transcriptomic analysis of bovine lymphocytes and compared the involved cytokines, genes, and pathways between high vs control and low vs control. Our data suggest that the low folic acid supplementation (120 mg/500 kg) could be a good choice to boost appropriate immunity and anti-inflammation as well as might being applied to the health improvement of perinatal dairy cows.

      • KCI등재

        Ginsenoside Rk1 inhibits HeLa cell proliferation through an endoplasmic reticulum signaling pathway

        Qiuyang Li,Hang Sun,Shiwei Liu,Jinxin Tang,Shengnan Liu,Pei Yin,Qianwen Mi,Jingsheng Liu,Lei yu,Yunfeng Bi 고려인삼학회 2023 Journal of Ginseng Research Vol.47 No.5

        Background: Changes to work-life balance has increased the incidence of cervical cancer among youngerpeople. A minor ginseng saponin known as ginsenoside Rk1 can inhibit the growth and survival ofhuman cancer cells; however, whether ginsenoside Rk1 inhibits HeLa cell proliferation is unknown. Methods and results: Ginsenoside Rk1 blocked HeLa cells in the G0/G1 phase in a dose-dependentmanner and inhibited cell division and proliferation. Ginsenoside Rk1 markedly also activated theapoptotic signaling pathway via caspase 3, PARP, and caspase 6. In addition, ginsenoside Rk1 increasedLC3B protein expression, indicating the promotion of the autophagy signaling pathway. Protein processingin the endoplasmic reticulum signaling pathway was downregulated in Gene Ontology (GO) andKyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses, consistent with tealtimequantitative PCR and western blotting that showed YOD1, HSPA4L, DNAJC3, and HSP90AA1expression levels were dramatically decreased in HeLa cells treated with ginsenoside Rk1, with YOD1was the most significantly inhibited by ginsenoside Rk1 treatment. Conclusion: These findings indicate that the toxicity of ginsenoside Rk1 in HeLa cells can be explained bythe inhibition of protein synthesis in the endoplasmic reticulum and enhanced apoptosis, with YOD1acting as a potential target for cervical cancer treatment.

      • KCI등재

        Black rice anthocyanidins prevent retinal photochemical damage via involvement of the AP-1/NF-κB/Caspase-1 pathway in Sprague-Dawley Rats

        Hao Jia,Wei Chen,Xiuhua Wu,Shuai Li,Hong Liu,Jiru Liao,Weihua Liu,Mantian Mi,Longjian Liu,Daomei Cheng,Xiaoping Yu 대한수의학회 2013 Journal of Veterinary Science Vol.14 No.3

        The effects of black rice anthocyanidins (BRACs) on retinal damage induced by photochemical stress are not well known. In the present study, Sprague-Dawley rats were fed AIN-93M for 1 week, after which 80 rats were randomly divided into two groups and treated with (n = 40) or without BRACs (n =40) for 15 days, respectively. After treatment, both groups were exposed to fluorescent light (3,000 ± 200 lux; 25oC), and the protective effect of dietary BRACs were evaluated afterwards. Our results showed that dietary BRACs effectively prevented retinal photochemical damage and inhibited the retinal cells apoptosis induced by fluorescent light (p < 0.05). Moreover, dietary BRACs inhibited expression of AP-1 (c-fos/c-jun subunits), up-regulated NF-κB (p65) expression and phosphorylation of IκB-α, and decreased Caspase-1 expression (p < 0.05). These results suggest that BRACs improve retinal damage produced by photochemical stress in rats via AP-1/NF-κB/Caspase-1apoptotic mechanisms.

      • KCI등재

        국내 옥수수 품종 및 계통의 미숙배 배양으로부터 Yellowish Friable Embryogenic 캘러스 (YFEC) 생산과 식물체 재생

        조미애,박윤옥,김진석,박기진,민황기,유장렬,최필선,Cho Mi-Ae,Park Yun-Ok,Kim Jin-Suck,Park Ki-Jin,Min Hwang-Ki,Liu Jang-Ryol,Choi Pil-Son 한국식물생명공학회 2005 식물생명공학회지 Vol.32 No.2

        국내 옥수수 3품종 (두메찰, 미백찰, 흑점찰)과 5 계통(HW1, KL103, HW3, HW4, KW7)의 미숙배를 1 mg/L 2,4-D, 25 mM proline, 100 mg/L casamino acid, 3 mM MES, 1.7 mg/L $AgNO_3$, Eriksson's vitamin 및 20 g/L sucrose가 첨가된 MS배지 (SEM)에 5주 동안 배양하였다. 각 계통 및 품종의 체세포배 발생 빈도는 HW1 (45.20%), KL103 (5.75%), HW3 (37.20%), HW4 (30.10%), KW70 (55.20%), 미백찰 (18.74%), 흑점찰 (22.41%), 두메찰 (36.72%)이었으며, 모델 품종인 Hi II type에서는 10% 이하였다. Hi II계통에서 형성되는 type II캘러스와 같은 노란색의 부드러운 배발생캘러스 (yellowish friable embryogenic callus, YFEC)는 오직 HW3와 흑점찰 품종에서 형성되었으며, 반면 다른 품종 및 계통에서는 late-embryo단계의 단단한 체세포배가 직접 발생되거나 형태적으로 비정상 모양을 갖는 단단하고 팽창된 체세포배가 발생 되었다. 노란색의 부드러운 배발생캘러스 (yellowish friable embryogenic callus, YFEC)는 동일배지에서 빠르게 증식 되었고 6개월 이상 배발생 능이 유지 되었으며, 1차 재분화 배지와 2차 재분화배지에 옮겼을 때 모두 식물체로 전환 되었다. 그러나 단단한 노란색의 배발생캘러스와 비정상 형태의 체세포배는 동일배지에서 매우 느리게 증식되었고, 재분화 배지에서 낮은 식물체 전환율 (25%)을 보였다. 따라서 본 연구로부터 선발된 HW3와 흑점찰은 향후 국내 옥수수 유전자원을 이용한 형질전환 시스템 개발연구에 이용 될 수 있을 것으로 예상된다. Immature embryos of 3 cultivars (Du Me Chal, Mi Baek Chal, Heug Jeom Chal) and 5 genotypes (HW1, KL103, HW3, HW4, KW7) were cultured on medium containing MS salts, Eriksson's vitamins, 1 mg/L 2,4-dichlorophenoxyacetic acid, 25 mM proline, 100 mg/L casamino acid, 3 mM MES, 1.7 mg/L $AgNO_3$ and 20 g/L sucrose (SIM). Frequency of somatic embryo formation on explant of immature embryos showed in HW1 (45.20%), KL103 (5.75%), HW3 (37.20%), HW4 (30.10%), KW70 (55.20%), Mi Baek Chal (18.74%), Heug Jeom Chal (22.41%), Du Me Chal (36.72%) and Hi II type (<10%), respectively. Yellowish friable embryogenic callus (YFEC) such as type II callus of Hi II genotype only produced from the HW3 and Heug Jeom Chal, whereas other cultivars and genotypes were directly formed somatic embryos with late-embryonic stages or expanded yellowish compact somatic embryo with morphological abnormality. The yellowish friable embryogenic callus (YFEC) could be proliferated on the same medium, which were maintained embryogenic capacity for 6 months over. Upon transfer to first regeneration and second regeneration medium, somatic embryos converted to plantlets at a frequency of approximately 100%. However, the expanded somatic embryos with abnormal morphology were slowly proliferated when subcultured on the same medium, and some of them were degenerated or converted to plantlets at a frequency of approximately 25%. Accordingly, The Heug Jeom Chal and HW3 genotype will be further used for development of high frequency transformation system in domestic maize germplasm.

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